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137篇 您的检索式:作者名="Bendayan"
    题名 作者 年代 出处 被引量
1Alteration of chaperonin60 and pancreatic enzyme in pancreatic acinar cell under pathological condition显示文摘AIM: To investigate the changes of chaperonin60 (Cpn60)and pancreatic enzymes in pancreatic acinar cells, and to explore their roles in the development of experimental diabetes and acute pancreatitis (AP).METHODS: Two different pathological models were replicated in Sprague-Dawley rats: streptozotocininduced diabetes and sodium deoxycholate-induced AP. The contents of Cpn60 and pancreatic enzymes in different compartments of the acinar cells were measured by quantitative immunocytochemistry.RESULTS: The levels of Cpn60 significantly increased in diabetes, but decreased in AP, especially in the zymogen granules of the pancreatic acinar cells. The elevation of Cpn60 was accompanied with the increased levels of pancreatic lipase and chymotrypsinogen in diabetes.However, a decreased Cpn60 level was accompanied by high levels of lipase and chymotrypsinogen in AP.The amylase level was markedly reduced in both the pathological conditions.CONCLUSION: The equilibrium between Cpn60 and pancreatic enzymes in the acinar cells breaks in AP, and Cpn60 content decreases, suggesting an insufficient chaperone capacity. This may promote the aggregation and autoactivation of the premature enzymes in the pancreatic acinar cells and play roles in the development of AP.Yong-Yu Li Moise Bendayan 2005World Journal of Gastroenterology2005,11,46:2
2Worth its weight in gold 显示文摘Bendayan M 2001Science2001,291,5507:1
3Functional expression and localization of P-glycoprotein in the central nervous system: relevance to the pathogenesis and treatment of neurological disorders 显示文摘Lee G Bendayan R 2004Pharm Res2004,21,8:1
4Multidrug resistance associated proteins: expression and function in the central nervous sys- tem 显示文摘Dallas S Miller DS Bendayan R 2006Pharmacol Rev2006,58,2:1
5Nanotechnological advances for the delivery of CNS therapeutics显示文摘Wong IlL Wu XY Bendayan R 2012Adv Drug Deliv Rev2012,64,7:1
6Multidrug resistance-associated proteins: expression and function in the central nervous system显示文摘Dallas S Miller DS Bendayan R 2006Pharmacol Rev2006,58,2:1
7Cross-talk between adipose and gastric leptins for the control of food intake and energy metabolism显示文摘Philippe G. Cammisotto émile Levy Ludwik J. Bukowiecki Moise Bendayan 2010Progress in Histochemistry and Cytochemistry2010,,3:1
8In situ localization of p-glycoprotein (abcb1) in human and rat brain 显示文摘Bendayan R Ronaldson PT Gingras D 2006J Histochem Cytochem2006,54,10:1
9A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymerlipid hybrid nanoparticle syslem显示文摘Wong HL Bendayan R Rauth AM 2006J Pharmacol Exp Ther2006,317,:1
10Effect of tissue processing on colloidal gold cytochemistry 显示文摘Bendayan M Nanci A Kan FW 1987J Histochem Cytochem1987,35,9:1
11Ultrastructural localization of antigenic sites on osmium-fixed tissues applying the protein Agold technique显示文摘Bendayan M Zollinger M 1983J Histochem Cytochem1983,31,:1
12Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles显示文摘Ho Lun Wong Reina Bendayan Andrew Rauth Yongqiang Li Xiao Wu 0,,:1
13High-resolution ultrastructura study of the rat glomerular basement membrane in long-term experimental diabetes显示文摘Inoue S Bendayan M 1995Ultrastruct Pathol1995,19,3:1
14Expression of ATP-binding cassette membrane transporters in rodent and human Sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier 显示文摘Robillard KR Hoque T Bendayan R 2012J Pharmacol Exp Ther2012,340,:1
15Muhidrug resistance-associated proteins: expression and function in the central nervous system显示文摘Dallas S Miller DS Bendayan R 2006Pharmacol Rev2006,58,2:1
16Successful steroid withdrawal in lung transplant recipients: result of a pilot study显示文摘Shitrit D Bendayan D Sulkes J 2005Respir Med2005,99,5:1
17Pulmonary hypertension-classifica- tion and treatment: new guidelines 显示文摘Bendayan D Kramer MR 2005Harefuah2005,144,3:1
18Hyperuricemia as a prognostic factor in pulmonary arterial hypertension显示文摘Bendayan D Shitrit D Ygla M 2003Respir Med2003,97,2:1
19Concomitant upper - lobe bullous emphysema, lower - lobe interstitial fibrosis and pulmonary hypertension in heavy smokers: report of eight cases and review of the literature显示文摘Grubstein A Bendayan D Schactman I 2005Respir Med2005,99,8:1
20Active tuberculosis andhuman immunodeficieney virus co-infection in Israel: a retro- spective study 显示文摘Bendayan D Littman K Polansky V 2010Isr Med Assoc J2010,12,2:1
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