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| 1 | Non-invasive means of measuring hepatic fat content显示文摘Hepatic steatosis affects 20% to 30% of the general adult population in the western world. Currently, the technique of choice for determining hepatic fat deposition and the stage of fibrosis is liver biopsy. However, it is an invasive procedure and its use is limited, particularly in children. It may also be subject to sampling error. Non-invasive techniques such as ultrasound, computerised tomography (CT), magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H MRS) can detect hepatic steatosis, but currently cannot distinguish between simple steatosis and steatohepatitis, or stage the degree of fibrosis accurately. Ultrasound is widely used to detect hepatic steatosis, but its sensitivity is reduced in the morbidly obese and also in those with small amounts of fatty infiltration. It has been used to grade hepatic fat content, but this is subjective. CT can detect hepatic steatosis, but exposes subjects to ionising radiation, thus limiting its use in longitudinal studies and in children. Recently, magnetic resonance (MR) techniques using chemical shift imaging have provided a quantitative assessment of the degree of hepatic fatty infiltration, which correlates well with liver biopsy results in the same patients. Similarly, in vivo 1H MRS is a fast, safe, non-invasive method forthe quantification of intrahepatocellular lipid (IHCL) levels. Both techniques will be useful tools in future longitudinal clinical studies, either in examining the natural history of conditions causing hepatic steatosis (e.g. non-alcoholic fatty liver disease), or in testing new treatments for these conditions. | Sanjeev R Mehta E Louise Thomas Jimmy D Bell Desmond G Johnston Simon D Taylor-Robinson | 2008 | World Journal of Gastroenterology2008，14，22： | 21 |
| 2 | Models and algorithms for road network design:A review and some new developments显示文摘 | YANG H BELL M G H | 1998 | Transport Review1998，18，3： | 2 |
| 3 | Effects of purified dies containing different combinations of arachidonic and docosahexaenoic acid on survival, growth and fatty acid composition of juvenile turbot (Scophthalmus maximus) 显示文摘 | Castell J D Bell J G Tocher D R | 1994 | Aquaculture1994，1，： | 2 |
| 4 | Benefiting from network position: firm capabilities, structural holes, and performance 显示文摘 | Zaheer A Bell G | 2005 | Strategic Management Journal2005，26，9： | 1 |
| 5 | Abundance and partitioning of OH in a hlgh-pressure magmatic system: Megacrysts from the Monastery kimberlite, South Africa显示文摘 | Bell D B Rossman G R Moore R O | 2004 | J Petrol2004，45，： | 1 |
| 6 | Relationship between degree of viremia and disease manifestations in calves with experimentally induced bovine viral diarrhea virus infection显示文摘 | Bell T G | 2001 | Americal Journal of Veterinary Research2001，62，7： | 1 |
| 7 | A game theory approach to measuring the performance reliability of transport networks显示文摘 | Bell M G H | 2000 | Transportation Research: Part B2000，34，6： | 1 |
| 8 | Interleukin 12p40 is required for dendritic cell migration and T cell priming af- ter Mycobacterium tuberculosis infection 显示文摘 | Khader S Partida Sanchez S Bell G | 2006 | J Exp Med2006，203，7： | 1 |
| 9 | Positional enhancer-blocking activity of the chickenβ-globin 5'HS4 insulators in transiently transfected cells显示文摘 | Recillas-Targa F Bell AC Felsenfeld G | 1999 | Proc Nail Acad Sci USA1999，96，14： | 1 |
| 10 | Analysis of fMRI data by blind separation into independent spatial components 显示文摘 | Mckeown M J Makelg S Brown G G Jung T P Kinderman S S Bell A J and Sejnowski T J | 1998 | Human Brain Mapping1998，6，： | 1 |
| 11 | A physicochemical study of the aging of colloidal sillica gels used in zeolite Y synthesis显示文摘 | Ginter D M Went G T Bell A T | 1992 | Zeolites1992，12，： | 1 |
| 12 | Development of broodstock diets for the European sea bass (Dicentrarchus labrax)with special emphasis on the importance of n-3 and n-6 HUFA to reproductive performance 显示文摘 | Bruce M P Oyen F Bell J G | 1999 | Aquaculture1999，177，： | 1 |
| 13 | A high-order projection method for tracking fluid interface in variable density incompressible flows显示文摘 | Puckett E G Almgren A S Bell J B | 1997 | Compute Phys1997，130，： | 1 |
| 14 | Modeling the capacity and level of service of urban transportation network显示文摘 | YANG HAI BELL M G H MENG QIANG | 2000 | Transportation Research Part B2000，34，4： | 1 |
| 15 | Assessment of cement o-PFA and lime-PFAused to stabilizer clay-size materials显示文摘 | Bell F G | 1994 | Bulletin of theIntermational Association of Engineering Geology1994，，49： | 1 |
| 16 | Lithography using ultrathin resist films显示文摘 | See E G Pike C Bell S | 2000 | U J Vac Sci Technol B2000，18，： | 1 |
| 17 | Shortest path in a network with time-dependent flow speed 显示文摘 | Kiseok Sung Michael G H Bell Myeongki Seong | 2000 | European Journal of Operational Re- search2000，121，1： | 1 |
| 18 | Evaluation of two post core systems using two different methods( fracture strength test and a finite elemental stress analysis ) 显示文摘 | Eskitaseioglu G Bell S Kalkan M | 2002 | J Endod2002，28，9： | 1 |
| 19 | Some effects of selenium deficiency on glutathione peroxidase activity and tissue pathology in rainbow trout (Salmo gairdneri) 显示文摘 | BELL J G PIRIE B ADRON J W | 1986 | Br J Nutr1986，55，2： | 1 |
| 20 | Noninvasive assessment of pul- monary artery flow and resistance by cardiac magnetic resonance in congenital heart diseases with unrestricted left-to-right shunt 显示文摘 | Bell A Beerbaum P Greil G | 2009 | JACC Cardiovasc Imaging2009，2，11： | 1 |
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