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| 1 | Targeted therapy in advanced metastatic colorectal cancer: Current concepts and perspectives显示文摘The introduction of new cytotoxic substances as well as agents that target vascular endothelial growth factor(VEGF)and epidermal growth factor receptor(EGFR)signaling has improved clinical outcome of patients withmetastatic colorectal cancer(mCRC).In this review we summarize the most relevant clinical data on VEGF and EGFR targeting regimens in mCRC.The effects of available treatment strategies for mCRC are often temporary,with resistance and disease progression developing in most patients.Thus,new treatment strategies are urgently needed.Some GI peptides including gastrin and gastrin releasing peptide,certain growth factors such as insulin-like growth factor-ⅠandⅡand neuropeptides such as growth hormone releasing hormone(GHRH)are implicated in the growth of CRC.Experimental investigations in CRC with antagonistic analogs of bombesin/gastrin-releasing peptide,GHRH,and with cytotoxic peptides that can be targeted to peptide receptors on tumors,are summarized in the second part of the review. | Florian Hohla Thomas Winder Richard Greil Ferenc G Rick Norman L Block rew V Schally | 2014 | World Journal of Gastroenterology2014，20，20： | 3 |
| 2 | Review: aqueous tape casting of ceramic powders显示文摘 | Hotza D Greil G | 1995 | Materials Science and Engineering1995，202，： | 1 |
| 3 | Noninvasive assessment of pul- monary artery flow and resistance by cardiac magnetic resonance in congenital heart diseases with unrestricted left-to-right shunt 显示文摘 | Bell A Beerbaum P Greil G | 2009 | JACC Cardiovasc Imaging2009，2，11： | 1 |
| 4 | Noninvasive assessment of pulmonary artery flow and resistance by cardiac magnetic reso-nance in congenital heart diseases with unrestricted left-to-right shunt显示文摘 | Bell A Beerbaum P Greil G | | JACC Cardiovasc Imaging0，，： | 1 |
| 5 | Three-dimensional mor- phological magnetie resonance imaging in infants and children with congenital heart disease显示文摘 | Fenchel M Greil G F Martirosian P et ol | 2006 | Pediatr Radiol2006，36，12： | 1 |
| 6 | Noninvasive assessment of pulmonary artery flow and resistance by cardiac magnetic resonance in congenital heart diseases with unrestricted left-to-right shunt显示文摘 | Bell A Beerbaum P Greil G | 2009 | JACC Cardiovasc Imaging2009，2，11： | 1 |
| 7 | Neoadjuvant chemother-apy and targeted therapy in breast cancer:past, present, and future显示文摘 | Gampenrieder SP Rinnerthaler G Greil R | | 0，，： | 1 |
| 8 | Neoadjuvant Chemotherapy and Targeted Therapy in Breast Cancer: Past,Present,and Future显示文摘 | Gampenrieder SP Rinnerthaler G Greil R | 2013 | J Oncol2013，2013，73： | 1 |
| 9 | Coronary magnetic resonance angiography in adolescents and young adults with Kwasaki disease显示文摘 | Greil G F Stuber M Botnar R M | 2002 | Circulation2002，105，8： | 1 |
| 10 | Effect of acquisition parameters on the accuracy of Velocity Encoded Cine Magnetic Resonance hnaging blood flow measurements 显示文摘 | Greil G Geva T Maier SE | 2002 | J Magn Reson Imaging2002，15，1： | 1 |
| 11 | Imaging of aortopulmo- nary collateral arteries with high resolution multidetector CT 显示文摘 | Greil G F M Schoebinger | 2006 | Pediatr Radio12006，36，6： | 1 |
| 12 | Leg ulcers associated with long-term hydroxyurea therapy显示文摘 | Weinlich G Schuler G Greil R | 1998 | JAm Acad Dermatol1998，39，2： | 1 |
| 13 | Effect of Acquisition Parameters on the Accuracy of Velocity Encoded Cine Magnetic Resonance Imaging Blood Flow Measurements显示文摘 | Greil G Geva T Maier SE | 2002 | Magn Reson lmaging2002，15，1： | 1 |
| 14 | Effect of acquisition parameters on the accuracy of velocity encoded cine magnetic resonance imaging blood flow measurements 显示文摘 | Greil G Geva T Maier SE | 2002 | J Magn Reson Imaging2002，15，1： | 1 |
| 15 | Neoadjuvant chemotherapy and targe- ted therapy in breast cancer: past, pres- ent,and future显示文摘 | Gampenrieder SP Rinnerthaler G Greil R | 2013 | J Oncol2013，2013，73： | 1 |
| 16 | The impact of hemoglobin levels on fatigue and quality of life in cancer patients显示文摘 | Holzner B Kemmler G Greil R | 2002 | Ann Oncol2002，13，： | 1 |
| 17 | Neoadjuvant chemotherapy and targeted therapy in breast cancer:past,present,and future显示文摘 | Gampenrieder SP Rinnerthaler G Greil R | 2013 | J Oncol2013，2013，73： | 1 |
| 18 | Randomized phase II study of the anti-epidermal growth factor receptor monoclonal antibody cetuximab with cisplatin versus cisplatin alone in patients with metastatic triplenegative breast cancer显示文摘 | BASELGA J GóMEZ P GREIL R | 2013 | J Clin Oncol2013，31，20： | 1 |
| 19 | Changes in carotid artery flow velocities after stent implantation: a fluid dynamics study with laser Doppler anemometry显示文摘 | Greil O Pflugeil G Weigand K | 2003 | J Endovasc Ther2003，10，2： | 1 |
| 20 | Effect of acquisition parameters on the accuracy of velocity encoded cine magnetic resonance imaging blood flow measurements显示文摘 | Greil G Geva T Maier SE | 2002 | J Magn Reson Imaging2002，15，1： | 1 |
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