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| 1 | Reliability and validity of the WHOQOL BRIEF in a sample of Brazilian outpatients with major depression 显示文摘 | Bedim M T Pavanello D P Caldieraro M A K | 2005 | Qual Life Res2005，14，2： | 1 |
| 2 | High-frequency re- petitive transcranial magnetic stimulation accelerates and enhances the clinical response to antidepressants in major depression: a meta-analysis of randomized, double-blind, and sham-controlled trials 显示文摘 | Bedim MT Van den Eynde F Daskalakis ZJ | 2013 | J Clin Psychiatry2013，74，2： | 1 |
| 3 | Quality of life and de- pression symptoms in patients with major depression and end - stage renal disease: amatehed pair study 显示文摘 | Bedim MT Mattevi BS Duarte AP | 2006 | J Psyehosom Res2006，61，5： | 1 |
| 4 | A systematic review and meta- analysis on the efficacy and acceptability of bilateral repetitive tran- seranial magnetic stimulation (rTMS) for treating major depression 显示文摘 | Bedim MT Vanden EF Daskalakis ZJ | 2012 | Psyehol Med2012，1，： | 1 |
| 5 | Quality of life and depressive symptoms inpatients with major depression and end-stage renal disease:A matched-pair study显示文摘 | Bedim MT Mattevi BS Duarte APG | | 0，，： | 1 |
| 6 | High-fre- quency repetitive transcranial magnetic stimulation acceler- ates and enhances the clinical response to antidepressants in major depression: a meta-analysis of randomized, double- blind, and sham-controlled trims 显示文摘 | Bedim MT Van den Eynde F Daskalakis ZJ | 2013 | J Clin Psychiatry2013，74，2： | 1 |
| 7 | Response, remission and drop-out rates following high-frequency repetitive tran- scranial magnetic stimulation (rTMS) for treating major depression: a systematic review and meta-analysis of randomized, double-blind and sham-controlled trials显示文摘 | Bedim MT van den Eynde F Tovar-Perdomo S | 2014 | Psychol Med2014，44，2： | 1 |
| 8 | Efficacy and acceptability of high frequency repetitive Iranscranial magnetic stimulation (rTMS) versus electroconvulsive therapy (ECT) for major depression: a systematic review and meta-analysis of random- ized trials 显示文摘 | Bedim MT Van den Eynde F Daskalakis ZJ | 2013 | Depress Anxiety2013，30，7： | 1 |
| 9 | High-frequency repedi- tire transcranial magnetic stimulation accelerates and enhances the clinical response to antidepressants in major depression:a meta-analy- sis of randomed, double-blind, and sham-controlled trials 显示文摘 | Bedim MT Van den Eynde F Daskalakis ZJ | 2013 | J Clin Psychiatry2013，74，2： | 1 |
| 10 | Temporal pattern of humoral immune response in mild cases of COVID-19显示文摘BACKGROUND Understanding the humoral response pattern of coronavirus disease 2019(COVID-19)is one of the essential factors to better characterize the immune memory of patients,which allows understanding the temporality of reinfection,provides answers about the efficacy and durability of protection against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),and consequently helps in global public health and vaccination strategy.Among the patients who became infected with SARS-CoV-2,the majority who did not progress to death were those who developed the mild COVID-19,so understanding the pattern and temporality of the antibody response of these patients is certainly relevant.AIM To investigate the temporal pattern of humoral response of specific immunoglobulin G(IgG)in mild cases of COVID-19.METHODS Blood samples from 191 COVID-19 real-time reverse transcriptase-polymerase chain reaction(RT-qPCR)-positive volunteers from the municipality of Toledo/Paraná/Brazil,underwent two distinct serological tests,enzyme-linked immunosorbent assay,and detection of anti-nucleocapsid IgG.Blood samples and clinicoepidemiological data of the volunteers were collected between November 2020 and February 2021.All assays were performed in duplicate and the manufacturers'recommendations were strictly followed.The data were statistically analyzed using multiple logistic regression;the variables were selected by applying the P<0.05 criterion.RESULTS Serological tests to detect specific IgG were performed on serum samples from volunteers who were diagnosed as being positive by RT-qPCR for COVID-19 or had disease onset in the time interval from less than 1 mo to 7 mo.The time periods when the highest number of participants with detectable IgG was observed were 1,2 and 3 mo.It was observed that 9.42%of participants no longer had detectable IgG antibodies 1 mo only after being infected with SARS-CoV-2 and 1.57%were also IgG negative at less than 1 mo.At 5 mo,3.14%of volunteers were IgG negative,and at 6 or 7 mo,1 volunteer(0.52%)had no detectable IgG.During the period between diagnosis by RT-qPCR/symptoms onset and the date of collection for the study,no statistical significance was observed for any association analyzed.Moreover,considering the age category between 31 and 59 years as the exposed group,the P value was 0.11 for the category 31 to 59 years and 0.32 for the category 60 years or older,showing that in both age categories there was no association between the pair of variables analyzed.Regarding chronic disease,the exposure group consisted of the participants without any comorbidity,so the P value of 0.07 for the category of those with at least one chronic disease showed no association between the two variables.CONCLUSION A temporal pattern of IgG response was not observed,but it is suggested that immunological memory is weak and there is no association between IgG production and age or chronic disease in mild COVID-19. | Isadora Maria Pilati Campos Milena Marques Gabrielle Caroline Peiter Ana Paula Carneiro Brandalize Mauricio Bedim dos Santos Fabrício Freire de Melo Kádima Nayara Teixeira | 2023 | World Journal of Biological Chemistry2023，14，2： | 0 |
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