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| 1 | An H3K27me3 demethylase-HSFA2 regulatory loop orchestrates transgenerational thermomemory in Arabidopsis显示文摘Global warming has profound effects on plant growth and fitness.Plants have evolved sophisticated epigenetic machinery to respond quickly to heat,and exhibit transgenerational memory of the heat-induced release of post-transtriptional gene silencing(PTGS).However,how thermomemory is transmitted to progeny and the physiological relevance are elusive.Here we show that heat-induced HEAT SHOCK TRANSCRIPTION FACTOR A2(HSFA2)directly activates the H3K27me3 demethylase RELATIVE OF EARLY FLOWERING 6(REF6),which in turn derepresses HSFA2.REF6 and HSFA2 establish a heritable feedback loop,and activate an E3 ubiquitin ligase,SUPPRESSOR OF GENE SILENCING 3(SGS3)-INTERACTING PROTEIN 1(SGIP1).SGIP1-mediated SGS3 degradation leads to inhibited biosynthesis of trans-acting siRNA(tasiRNA).The REF&HSFA2 loop and reduced tasiRNA converge to release HEAT-INDUCED TAS1 TARGET 5(HTT5),which drives early flowering but attenuates immunity.Thus,heat induces transmitted phe no types via a coordi nated epigenetic network involvi ng histone demethylases,tran scriptio n factors,and tasiRNAs,ensuring reproductive success and transgenerational stress adaptation. | Junzhong Liu Lili Feng Xueting Gu Xian Deng Qi Qiu Qun Li Yingying Zhang Muyang Wang Yiwen Deng Ertao Wang Yuke He Isabel Baurle Jianming Li Xiaofeng Cao Zuhua He | 2019 | Cell Research2019，29，5： | 10 |
| 2 | Soluble liver antigen: isolation of a 35-kd recombinant protein(SLA-p35) specifically recognizing sera from patients with autoimmune hepatitis 显示文摘 | Volkmann M Martin L Baurle A | 2001 | Hepatology2001，33，： | 1 |
| 3 | Hybrid simulation approach for cavity flows :blending , algorithm, and boundary treatment issues显示文摘 | Baurle R A Tam C J | 2003 | AIAA Journal2003，41，8： | 1 |
| 4 | Fundamental studies of cavity- based flameholder concepts for supersonic combustors 显示文摘 | Gruber M R Baurle R A | 2001 | Journal of Propulsion and Power2001，17，1： | 1 |
| 5 | Fundamental studies of cavity-based flameholder concepts for supersonic combustors 显示文摘 | Gruber M R Baurle R A Mathur T | 2001 | Journal of Propulsion and Power2001，17，1： | 1 |
| 6 | Red blood cell function in hypoxia at altitude and exercise显示文摘 | Heimomair Baurl | | 0，，： | 1 |
| 7 | Fundamental studies of cavity-based flameholder concepts for supersonic combustors 显示文摘 | Gruber M R Baurle R A | 2001 | Journal of Propulsion and Power2001，17，1： | 1 |
| 8 | The timing of developmental transitions in plants显示文摘 | Baurle I Dean C | 2006 | Cell2006，125，4： | 1 |
| 9 | Dependence of Parvalbumin expression of Purkinje cell input in the deep cerebellar nuclei显示文摘 | Baurle J Hoshi M Grusser-Cornehls U | 1998 | J Comp Neurol1998，392，： | 1 |
| 10 | Fundamental Studies of Cavity-Based Flameholder Concepts for Supersonic Combustors 显示文摘 | Gruber M R Baurle R A Mathur T | 2001 | Journal of Propulsion and Power2001，17，1： | 1 |
| 11 | The timing of developmental transi- tions in plants 显示文摘 | BAURLE I DEAN C | 2006 | Cell2006，125，： | 1 |
| 12 | Hybrid simulation approach for cavity flows: blending algorithm and boundary treatment issues显示文摘 | Baurle R A Tam C J Edwards J R | 2003 | AIAA Journal2003，41，8： | 1 |
| 13 | Hybrid Simulation Approach for Cavity Flows: Blending, Algorithm, and Boundary Treatment Issues 显示文摘 | R A Baurle C J Tam | 2003 | AIAA Journal (S0001-1452)2003，841，8： | 1 |
| 14 | Obesity in children and young people: a crisis in public health 显示文摘 | Lobstein T BaurL Uauy R | 2004 | Obes Rev2004，，： | 1 |
| 15 | Fundamental studies of cavity-based flameholder concepts for supersonic combustors显示文摘 | Gruber M R Baurle R A Mathur T K | 2001 | Journal of Propulsion and Power2001，17，1： | 1 |
| 16 | Lowglycemicindexorlowglycemicloaddietsforoverweightandobesity显示文摘 | ThomasDE ElliottEJ BaurL | 2007 | CochranceDatabaseSystRew2007，18，： | 1 |
| 17 | Hybrid Simulation Approach for Cavity Flows:Blending,Algorithm,and Boundary Treatment Issues显示文摘 | Baurle R A Tam C J Edwards J R | 2003 | AIAA Journal2003，41，8： | 1 |
| 18 | The timing of developmental transitions in plants显示文摘 | BAURLE I DEAN C | 2006 | Cell2006，125，4： | 1 |
| 19 | Differential regulation of bcl-2, bax,c-fos, jun-b, and krox-24 expression in the cerebellun of purkinje cell degenerationmutant mice 显示文摘 | Gillardon F Baurle J Wickert J | 1995 | J Neuro Res1995，41，5： | 1 |
| 20 | Apicalmeristems:the plant' s fountain of youth显示文摘 | BAURLE I LAUX T | | 0，，： | 1 |
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