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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Randomized Controlled trial of outpatient mentalization-based treatment versus structured clinical management for borderline personality disorder显示文摘 | Bateman A Fonagy P | 2009 | Am J Psychiatry2009，166，： | 1 |
| 3 | Mucosal expression of cyclooxygenase isoforms 1 and 2 is increased with worsening damage to the gastric mucosa显示文摘 | A C Bateman R L Mehta | 2005 | Histopathology2005，46，3： | 1 |
| 4 | Psychotherapy for Borderline Personality Disorder: mentalization- based treatment显示文摘 | Bateman A Fonagy P | 2004 | New York: Oxford University Press2004，，： | 1 |
| 5 | Bound and path effects in double and triple bounded dichotomous choice contingent valuation 显示文摘 | Langford I H Jones A P | 2001 | Resources and Energy Economics2001，23，： | 1 |
| 6 | Mixing of cordierit granitoid and proxene gabbro, and fractionation, in the Santa Olallatonlite (Andaluc) 显示文摘 | MART M P CASTRO A | 1992 | Lithos1992，28，： | 1 |
| 7 | Antibodies to type Ⅱ collagen in SLE : a role in the pathogenesis of deforming arthristis 显示文摘 | Choi E K Gatenby P A Bateman J F | 1990 | Immunol Cell Biol1990，，： | 1 |
| 8 | The Pfam protein families database 显示文摘 | Punta M Coggill P C Eberhardt R Y Mistry J Tate J Boursnell C Pang N Forslund K Ceric G Clements J Hcger A Holm L Sonnhammer E L Eddy S R Bateman A Finn R D | 2012 | Nucleic Acids Research2012，40，： | 1 |
| 9 | Appling GIS to environmental and resource economics显示文摘 | Bateman I J Jones A P Lovett A A | 2002 | Environmental and Resource Economics2002，22，： | 1 |
| 10 | DUFs:families in search of function显示文摘 | Bateman A Coggill P Finn R D | 2010 | Acta Crystallographica Section F-Structural Biology and Crystallization Communications2010，66，10： | 1 |
| 11 | The granulin gene family:from cancer to dementia显示文摘 | Bateman A Bennett H P | 2009 | Bioessays2009，31，： | 1 |
| 12 | RNIE:genome-wide prediction of bacterial intrinsic terminators显示文摘 | GARDNER P P BARQUIST L BATEMAN A | 2011 | Nucleic Acids Research2011，39，14： | 1 |
| 13 | Granulins:the structure and function of an emerging family of growth factors显示文摘 | Bateman A Bennett H P | 1998 | Journal of Endocrinology1998，158，： | 1 |
| 14 | Mechanism for the role of magnesia in the sintering of alumina containing small amounts of a liquid phase 显示文摘 | BATEMAN C A BENNISON S J HA1MER M P | 1989 | J Am Ceram Soc1989，72，7： | 1 |
| 15 | Reducing gain-loss asymmetry: A virtual reality choice experiment valuing land use change显示文摘 | Bateman I J Day B H Jones A P | 2009 | Journal of Environmental Economics and Management2009，58，1： | 1 |
| 16 | Tiotropium is noninferior to sal-meterol in maintaining improved lung function in B16-Arg/Arg patients with asthma显示文摘 | Bateman E D Kornmann 0 Schmidt P Pivovarova A Engel M Fabbri L M | 2011 | J Allergy Clin Im-munol2011，128，： | 1 |
| 17 | The Pfam protein families database 显示文摘 | Finn RD Mistry J Tate J Coggill P Heger A Pollington JE Gavin OL Gunasekaran P Ceric G Forslund K Holm L Sonnhammer EL Eddy SR Bateman A | 2010 | Nucleic Acids Res2010，38，： | 1 |
| 18 | The effectiveness of partial hospitalisation in the treatment of borderline personality disorder: a randomized controlled trial显示文摘 | Bateman A W Fonagy P | 1999 | American Journal of Psychiatry1999，156，： | 1 |
| 19 | Effectiveness of partial hospitalization in the treatment of borderline personality disorder: A randomized con- trolled trial显示文摘 | Bateman A Fonagy P | 1999 | Am J Psychiatry1999，156，： | 1 |
| 20 | KIR and their role in disease 显示文摘 | Williams A P Bateman A R Khakoo S I | 2005 | Molecular Interventions2005，5，4： | 1 |
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