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| 1 | Copy number variation and selection during reprogramming to pluripo- teney显示文摘 | Hussein SM Batada NN Vuoristo S | 2011 | Nature2011，471，7336： | 1 |
| 2 | Evolution of chromosome organization driven by selection for reduced gene expression noise显示文摘 | Batada N N Hurst L D | 2007 | Nature Genetics2007，39，： | 1 |
| 3 | Copy number variation and selection during reprogramming to pluripotency显示文摘 | Hussein SM Batada NN Vuoristo S | | 0，，7336： | 1 |
| 4 | Copynumber variation and selection during reprogramming topluripotency显示文摘 | HUSSEIN S M BATADA N N VUORISTO S | 2011 | Nature2011，471，7336： | 1 |
| 5 | Copy number variation and selection during reprogramming to pluripotency 显示文摘 | Hussein SM Batada NN Vuoristo S | 2011 | Nature2011，471，7336： | 1 |
| 6 | Effect of exercise intensity and duration on capillary glucose responses in pregnant women at low and high risk for gestational diabetes显示文摘 | S.‐M. Ruchat M. H. Davenport I. Giroux M. Hillier A. Batada M. M. Sopper R. McManus J.‐A. Hammond M. F. Mottola | 2012 | Diabetes Metab Res Rev2012，，： | 1 |
| 7 | Effect of exercise intensity and duration on capillary glucose responses in pregnant women at low and high risk for gestational diabetes显示文摘 | S.‐M. Ruchat M. H. Davenport I. Giroux M. Hillier A. Batada M. M. Sopper R. McManus J.‐A. Hammond M. F. Mottola | 2012 | Diabetes Metab Res Rev2012，，8： | 1 |
| 8 | Copy number variation and selection during reprogramming to pluripotency显示文摘 | Hussein SM Batada NN Vuoristo S | 2011 | Nature2011，471，7336： | 1 |
| 9 | Copy number variation and selection during reprogramming to pluripotency 显示文摘 | Hussein SM Batada NN Vuoristo S | 2011 | Nature2011，471，7336： | 1 |
| 10 | Copy number variation and selection during reprogramming to pluripoteney显示文摘 | Hussein SM Batada NN Vuoristo S | 2011 | Nature2011，471，7336： | 1 |
| 11 | Copy number variation and selection during reprogramming to pluripotency显示文摘 | Hnssein S M Batada N N Vuoristo S Ching R W Autio R N(a)rv(a)E Ng S Sourour M H(a)m | | 0，，7336： | 1 |
| 12 | In- spiring Children as Storytellers in India 显示文摘 | Ameena Batada Ira Joshi Garima Sharma Swati Mehta | 2010 | Yong children november2010，65，6： | 1 |
| 13 | Evolutionary and physiologi- cal importance of hub proteins 显示文摘 | BATADA N N HURST L D TYERS M | 2006 | PLoS Computational Biology2006，2，7： | 1 |
| 14 | Copy number variation and selection during reprogramming to pluripotency显示文摘 | Hussein SM Batada NN Vuodsto S | 2011 | Nature2011，471，7336： | 1 |
| 15 | Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors显示文摘The conversion of somatic cells into pluripotent stem cells via overexpression of reprogramming factors involvesepigenetic remodeling. DNA methylation at a significant proportion of CpG sites in induced pluripotent stem cells(iPSCs) differs from that of embryonic stem cells (ESCs). Whether different sets of reprogramming factors influencethe type and extent of aberrant DNA methylation in iPSCs differently remains unknown. In order to help resolvethis critical question, we generated human iPSCs from a common fibroblast cell source using either the Yamanakafactors (OCT4, SOX2, KLF4 and cMYC) or the Thomson factors (OCT4, SOX2, NANOG and LIN28), and determinedtheir genome-wide DNA methylation profiles. In addition to shared DNA methylation aberrations present in all ouriPSCs, we identified Yamanaka-iPSC (Y-iPSC)-specific and Thomson-iPSC (T-iPSC)-specific recurrent aberrations.Strikingly, not only were the genomic locations of the aberrations different but also their types: reprogrammingwith Yamanaka factors mainly resulted in failure to demethylate CpGs, whereas reprogramming with Thomsonfactors mainly resulted in failure to methylate CpGs. Differences in the level of transcripts encoding DNMT3b andTET3 between Y-iPSCs and T-iPSCs may contribute partially to the distinct types of aberrations. Finally, de novoaberrantly methylated genes in Y-iPSCs were enriched for NANOG targets that are also aberrantly methylated insome cancers. Our study thus reveals that the choice of reprogramming factors influences the amount, location,and class of DNA methylation aberrations in iPSCs. These findings may provide clues into how to produce humaniPSCs with fewer DNA methylation abnormalities. | Aline C Planello Junfeng Ji Vivek Sharma Rajat Singhania Faridah Mbabaali Fabian Müller Javier A Alfaro Christoph Bock Daniel D De Carvalho Nizar N Batada | 2014 | Cell Regeneration2014，3，1： | 0 |
| 16 | 用FPGA实现智能天线的波束赋形功能显示文摘 | Deepak BoppanaAsif Batada Altera公司 | 2004 | 中国集成电路2004，13，12： | 0 |
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