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| 1 | Efficacy of low dose peginterferon alpha-2b with ribavirin on chronic hepatitis C显示文摘AIM: To assess the effi cacy of peginterferon alpha 2b at doses of 50 μg weekly and 80 μg weekly (based on body weight) plus ribavirin in HCV genotype 2 and genotype 3 chronic hepatitis C patients. METHODS: During the study period of Jan 2002 to Dec 2003, all patients diagnosed as chronic hepatitis C or HCV related compensated cirrhosis were treated with peginterferon alpha 2b 50 μg S/C weekly (body weight < 60 kg) or 80 μg S/C weekly (body weight > 60 kg) plus ribavirin 800 mg/d for 24 wk. RESULTS: Overall 28 patients, 14 patients in each group (based on body weight) were treated during the period. Out of 28 patients, 75% were genotype 3, 18% were genotype 2 and 7% were genotype 1. The mean dose of peginterferon alpha 2b was 0.91 μg/kg in group 1 and 1.23 μg/kg in group 2 respectively. The end of treatment and sustained virologic response rates were 82% and 78% respectively. Serious adverse effects were seen in 3.5% patients. CONCLUSION: Low dose peginterferon alpha 2b in combination with ribavirin for 24 wk is effective in HCV genotype 2 and 3 chronic hepatitis C patients. | Rajesh Gupta CH Ramakrishna Sandeep Lakhtakia Manu Tandan Rupa Banerjee D Nageshwar Reddy | 2006 | World Journal of Gastroenterology2006，12，34： | 10 |
| 2 | Healing property of the Piper betel phenol, allylpyrocatechol against indomethacin-induced stomach ulceration and mechanism of action显示文摘AIM: To evaluate the protective activity of allylpyrocatechol (APC), the major antioxidant constituent of Piper betel, against the indomethacin-induced stomach ulceration in the rat model and correlates with its antioxidative and mucin protecting properties. METHODS: Male Sprague-Dawley rats were divided into five groups. Normal control rats (group Ⅰ) were given the vehicle oral dose of gum acacia in distilled water (1 mL per rat); ulcerated control and treated rats (groups Ⅱ-Ⅴ) were given a single dose of indomethacin (30 mg/kg body wt.); group Ⅱ rats were sacrificed 4 h after indomethacin administration; groups Ⅲ-Ⅴ rats were given the vehicle (1 mL per rat) or APC (2 mg/kg body wt.) or misoprostol (1.43 μg/kg body wt.) once daily by oral intubation for 7 d starting from 4 h after the indomethacin administration. After 7 d, the stomach tissues were excised for histological examination and biochemical analysis. RESULTS: Treatment with APC (2 mg/kg body wt per day) and misoprostol (1.43 μg/kg body wt per day) for 7 d could effectively heal the stomach ulceration as revealed from the ulcer index and histopathological studies. Compared to the zero day ulcerated group, treatment with APC and misoprostol reduced the ulcer index by 93.4% and 85.4% respectively (P < 0.05). Both APC and misoprostol accelerated ulcer healing observed in natural recovery (P < 0.05), their respective healing capacities not being significantly different. The healing capacities of APC and misoprostol could be attributed to their antioxidant activity as well as the ability to enhancethe mucin content of the gastric tissues. Compared to the ulcerated untreated rats, those treated with APC and misoprostol showed near normal MDA levels, while the protein levels were 86% and 78% of the normal value respectively (P < 0.05). Likewise, both APC and misoprostol increased the SOD, catalase, and mucin levels significantly (P < 0.05), the effect of APC being better. CONCLUSION: APC can protect indomethacin-induced gastric ulceration due to its antioxidative and mucin protecting properties. | S Bhattacharya D Banerjee AK Bauri S Chattopadhyay SK Bandyopadhyay | 2007 | World Journal of Gastroenterology2007，13，27： | 4 |
| 3 | Integrating demand side options in electric utility planning: a multi-objective approach显示文摘 | Chattopadhyay D Banerjee R Parikh J | 1995 | IEEE Trans on Power Systems1995，10，2： | 2 |
| 4 | Aromatization of propene and n-butene over H-galloaluminosilicate (ZSM-5 tpe) zeolite显示文摘 | Choudhary V R Panjala D Banerjee S | | 0，，： | 2 |
| 5 | Glass and Mineral Chemistry of Northern Central Indian Ridge Basalts:Compositional Diversity and Petrogenetic Significance显示文摘The glass and mineral chemistry of basalts examined from the northern central Indian ridge (NCIR) provides an insight into magma genesis around the vicinity of two transform faults: Vityaz (VT) and Vema (VM). The studied mid-ocean ridge basalts (MORBs) from the outer ridge flank (VT area) and a near-ridge seamount (VM area) reveal that they are moderately phyric plagioclase basalts composed of plagioclase (phenocryst [An60-90] and groundmass [An35-79]), olivine (Fo81-88), diopside (Wo45-51, En25-37, Fs14-24), and titanomagnetite (FeOt~63.75 wt% and TiO2~22.69 wt%). The whole-rock composition of these basalts has similar Mg# [mole Mg/mole(Mg+Fe2+)] (VT basalt:~0.56-0.58; VM basalt:~0.57), but differ in their total alkali content (VT basalt:~2.65; VM basalt:~3.24). The bulk composition of the magma was gradually depleted in MgO and enriched in FeOt, TiO2, P2O5, and Na2O with progressive fractionation, the basalts were gradually enriched in Y and Zr and depleted in Ni and Cr. In addition, the ΣREE of magma also increased with fractionation, without any change in the (La/ Yb)N value. Glass from the VM seamount shows more fractionated characters (Mg#: 0.56-0.57) compared to the outer ridge flank lava of the VT area (Mg#: 0.63-0.65). This study concludes that present basalts experienced low-pressure crystallization at a relatively shallow depth. The geochemical changes in the NCIR magmas resulted from fractional crystallization at a shallow depth. As a consequence, spinel was the first mineral to crystallize at a pressure >10 kbar, followed by Fe-rich olivine at <10 kbar pressure. | Dwijesh RAY Ranadip BANERJEE Sridhar D IYER Basavaraju BASAVALINGU Subir MUKHOPADHYAY4 | 2009 | Acta Geologica Sinica(English Edition)2009，83，6： | 2 |
| 6 | Pesticide-induced oxidative stress:perspectives and trends显示文摘 | | 2001 | Rev Environ Health2001，16，： | 1 |
| 7 | Overexpression of E2F-1 in lung and liver metastases of human colon cancer is associated with gene amplification显示文摘 | Iwamoto M Banerjee D Menon LG | 2004 | Cancer Biol Tber2004，3，4： | 1 |
| 8 | A practical Approach for Routing and Wave- length Assignment in Large Wavelength-Routed Optical Networks显示文摘 | D Banerjee B Mukherjee | 1996 | IEEE Journal on Selected Areas in Communications1996，14，5： | 1 |
| 9 | Some principles for designing a wide area optical network显示文摘 | Mukherjee B Banerjee D Mukherjee A | 1996 | IEEE/ACM Transactions on Networking1996，4，5： | 1 |
| 10 | Equivalent dose estimation using a single aliquot of polymineral ne grains 显示文摘 | Banerjee D | 2001 | Radiation Measurements2001，33，： | 1 |
| 11 | Enhancement of electron field emission by carbon coating on vertically aligned Si nanowires显示文摘 | DAS N S BANERJEE D CHATTOPADHYAY K K | 2011 | Applied Surface Science2011，257，22： | 1 |
| 12 | Grain size and geochemical partitioning of heavy metals in sediments of the Damodar River--a tributary of the lower Ganga, India显示文摘 | Singh A K Hasnain S I Banerjee D K | 1999 | Environmental geology1999，39，1： | 1 |
| 13 | The de- scriptive epidemiology of e:pilepsy- a review 显示文摘 | BANERJEE P N FILIPPI D ALLEN HAUSER W | 2009 | Epilepsy Res2009，85，1： | 1 |
| 14 | Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis显示文摘 | Hernandez SL Banerjee D Garcia A | | 0，，01： | 1 |
| 15 | Early splenic metastaasis in a case of re- nal adenocarcinoma显示文摘 | Pal KK Guha D Banerjee D | 1995 | J Indian Med Assoc1995，93，7： | 1 |
| 16 | A comparative study of oral tramadol andibuprofen in postoperative pain in operations of lower abdomen显示文摘 | Banerjee M Bhaumik D J Ghosh A K | 2011 | J Indian MedAssoc2011，109，62： | 1 |
| 17 | Nanoscale TiB Pre- cipitates in Laser Deposited Ti-matrix Composites 显示文摘 | BANERJEE R GENC A HILL D | 2005 | Scripta Materialia2005，53，： | 1 |
| 18 | Rhinological complications of sublabjal transseptal transsphenoidal surgery for sellar and suprasellar lesion:prevention and management显示文摘 | Banerjee D | 1996 | Neurosurg Rev1996，19，： | 1 |
| 19 | Wavelength-routed Optical Networks: Linear Formulation, Resource Budgeting Tradeoffs, and a Reconfiguration Study显示文摘 | Banerjee D Mukherjee B | 2000 | IEEE/ACM Trans on Networking2000，8，5： | 1 |
| 20 | Increased resistance to methotrexate in human hematopoietic cells after gene transfer of the Ser31 DHFR mutant显示文摘 | Flasshove M Banerjee D Bertino J R | 1995 | Leukemia1995，9，1： | 1 |
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