|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Impaired immune reaction and increased lactate and C-reactive protein for early prediction of severe morbidity and pancreatic fistula after pancreatoduodenectomy显示文摘Background: Prediction of complications after pancreatoduodenectomy (PD) remains of interest. Blood parameters and biomarkers during rst and second postoperative days (POD1, POD2) may be early indi- cators of complications. Methods: This case-control study included 50 patients. Baseline, POD1 and POD2 values of leukocytes, neutrophils, lymphocytes, platelets, hemoglobin, C-reactive protein (CRP), procalcitonin and arterial lactate were compared between individuals presenting Clavien ≥ III morbidity, pancreatic stula (PF) or clinically relevant PF (CRPF) and those without these morbidities. Common variables reaching signi cance were further analyzed in order to calculate a predictive score. Results: Severe morbidity, PF and CRPF rates were 28.0%, 26.0% and 14.0%, respectively. Patients with severe morbidity had lower leukocytes on POD2 (P=0.04). Patients with PF presented higher CRP on POD2 (P=0.001), higher lactate on POD1 (P=0.007) and POD2 (P=0.008), and lower lymphocytes on POD1 (P=0.007) and POD2 (P=0.008). Patients with CRPF had lower leukocytes and neutrophils on POD1 (P =0.048, P =0.038), lower lymphocytes on POD1 (P =0.001) and POD2 (P =0.003), and higher CRP on POD2 (P =0.001). Baseline parameters and procalcitonin obtained no statistical associations. Score was de ned according to lymphocytes on POD1 < 650/μL and CRP on POD2 ≥ 250 mg/L allocating patients in 3 risk categories. PF and CRPF rates were statistically higher as risk category increased (P<0.001). Receiver operating characteristic curves and Hosmer Lemeshow tests showed a good accuracy. Conclusions: Impaired immunological reaction during early postoperative period (lower leukocytes and, particularly, lymphocytes) in response to surgical aggression would favor complications after PD. Likewise, acidosis (higher arterial lactate) could behave as risk factor of PF. An elevated CRP on POD2 is also an early biomarker of PF. Our novel score based on postoperative lymphocyte count and CRP seems reliable for early prediction of PF. | Mario Rodriguez-Lopez Francisco J.Tejero-Pintor Martin Bailon-Cuadrado Asterio Barrera-Rebollo Baltasar Perez-Saborido David Pacheco-Sanchez | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，1： | 8 |
| 2 | Microbiological Survey of the Human Gastric Ecosystem Using Culturing and Pyrosequencing Methods显示文摘 | Susana Delgado Raúl Cabrera-Rubio Alex Mira Adolfo Suárez Baltasar Mayo | 2013 | Microbial Ecology2013，，3： | 2 |
| 3 | Biochemistry and geneticsof insect resistance to Bacillus thuringiensis insecticidal crystalproteins 显示文摘 | Juan F Baltasar E Yolanda 'B^etal | 1995 | FEMS Microbiology Letters1995，132，12： | 1 |
| 4 | Sleeve gastrectomy in a 10-year-old child显示文摘 | Baltasar A Serra C Bou R | 2008 | Obes Surg2008，18，6： | 1 |
| 5 | Selected criteria for lactic acid bacteria to be used as functional starter cultures in dry sausages production: An update 显示文摘 | Mohammed S A Baltasar M | 2007 | Meat Science2007，76，： | 1 |
| 6 | Phenotypic and molecular identification of yeast species associated with Spanish blue-veined Cabrales cheese显示文摘 | Pablo álvarez-Martín Ana Belén Flórez Teresa María López-Díaz Baltasar Mayo | 2007 | International Dairy Journal2007，，8： | 1 |
| 7 | Laparoscopic sleeve gastrectomy: a multi-purpose operation 显示文摘 | Baltasar A Serra C Perez N | 2005 | Obes Surg2005，15，： | 1 |
| 8 | Laparoscopie reoperative sleeve gastrectomy 显示文摘 | Serra C Baltasar A Perez N | 2007 | Cir Esp2007，82，1： | 1 |
| 9 | Laparoscopic sleeve gastrectomy: a multipurpose bariatric operation 显示文摘 | Baltasar A Serra C Perez N | 2005 | Obes Surg2005，15，8： | 1 |
| 10 | PCR-DGGE as a tool for characterizing dominant microbial populations in the Spanish blue-veined Cabrales cheese显示文摘 | Ana Belén Fl'rez Baltasar Mayo 2006 | 2006 | International Dairy Journal2006，16，： | 1 |
| 11 | Use of a Roux limb to correct esophagogastric junction fistulas after sleeve gastrectomy 显示文摘 | Baltasar A Bou R Bengochea M | | Obes Surg0，17，10： | 1 |
| 12 | An autonomous wave-powered desalination system 显示文摘 | MATT Folley BALTASAR Penate Suarez Trevor Whittaker | 2008 | Desalination2008，220，： | 1 |
| 13 | Laparoscopic sleeve gastrectomy:a multipurpose bariatric operation显示文摘 | Baltasar A Serra C Pérez N | 2005 | Obes Surg2005，15，8： | 1 |
| 14 | An autonomous wave-powered desalination system显示文摘 | Matt Folley Baltasar Pe?ate Suarez Trevor Whittaker | 2008 | Desalination2008，220，： | 1 |
| 15 | Duodenal switch:an effective therapy for morbid obesity-intermediate reults显示文摘 | Baltasar A Bou R Bengochea M et a1 | 2001 | Obes Surg2001，11，1： | 1 |
| 16 | Antibiotic Susceptibility of Lactobacillus and Bifidobacterium Species from the Human Gastrointestinal Tract显示文摘 | Susana Delgado Ana Belén Flórez Baltasar Mayo | 2005 | Current Microbiology2005，，4： | 1 |
| 17 | Microbial diversity and succession during the manufacture and ripening of traditional, Spanish, blue-veined Cabrales chees, as determined by PCR-DGGE显示文摘 | Ana Belen Florez Baltasar Mayo | 2006 | International Journal of Food Microbiology2006，110，2： | 1 |
| 18 | Selection criteria for lactic acid bacteria to be used as functional starter cultures in dry sausage production:An update显示文摘 | Mohammed Salim Ammor Baltasar Mayo | 2007 | Meat Science2007，76，： | 1 |
| 19 | Identification of tet (M) in two Lactococcus lactis strains isolated from a Spanish traditional starter-free cheese made of raw milk and conjugative transfer of tetracycline resistance to lactococci and enterococci显示文摘 | Ana Belén Flórez Mohammed Salim Ammor Baltasar Mayo | 2007 | International Journal of Food Microbiology2007，，2： | 1 |
| 20 | PCR- DGGE as a tool for characterizing dominant microbial populations in the Spanish blue- veined Cabrales cheese显示文摘 | Ana Belen Florez Baltasar Mayo | 2006 | International Dairy Journal2006，16，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员