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| 1 | 2022年WHO甲状腺肿瘤分类概述显示文摘2022年WHO第5版甲状腺肿瘤分类按细胞起源、病理特征、分子分型及生物学行为,分为良性、低危组和恶性。新分类变化不少,作者做了综述。将发育异常甲状舌管纳入;为避免结节性甲状腺肿定义为增生性、肿瘤性或矛盾的“腺瘤样增生”,编委会达成共识,命名为甲状腺滤泡结节性病变(FND)。基于分子谱和侵袭性,多种形态亚型的甲状腺乳头状癌(PTC)代表了BRAF样癌(浸润性生长、核非典型明显);而包裹型浸润性乳头状癌滤泡变异型/[IEFVPC,分子检测证实与滤泡性甲状腺癌(FTC)关系密切,不再归于PTC]与FTC代表RAS样癌(膨胀性生长、核非典型轻度)。 | Baloch ZW Asa SL Barletta JA 方三高(译) 魏建国(校) | 2022 | 诊断病理学杂志2022，29，12： | 63 |
| 2 | 山新杨PdPapGH12基因克隆及其响应胁迫的组织表达显示文摘为筛选林木抗性基因,培育高抗转基因林木,以山新杨(Populus davidiana×P.alba var.pyramidlis)为试材,采用RT-PCR技术克隆获得1560 bp的PdPapGH12(Potri.004G109200.1)基因cDNA,生物信息学分析表明该基因编码519个氨基酸,该蛋白属于亲水性酸性蛋白。依据亚细胞定位预测结果推测其在胞内发挥水解的作用。蛋白结构分析发现PdPapGH12与4个杨树品种的9条GHs序列具有高度一致性。qRT-PCR分析显示,PdPapGH12在茎基、老叶和根中表达量更高。并发现200 mmol/L NaCl、pH为10的Na_(2)CO_(3)溶液和聚乙二醇6000(PEG 6000;质量分数30%)胁迫48 h其在茎尖、叶和根中均上调表达;5种植物致病病原真菌胁迫48 h均使其在茎尖的表达下调。只有核盘菌使其在叶中表达显著上调;尖孢镰刀菌、链格孢菌和立枯丝核菌使其在根内表达显著上调。受激素诱导48 h,ABA(100μmol/L)仅使其在根部表达上调;SA(100μmol/L)仅使其在叶中表达上调,而JA(100μmol/L)使其在叶和根中的表达均上调。结果表明PdPapGH12参与植物抵抗逆境胁迫和激素诱导的信号途径。 | 李素 陈芳 殷缘 田广宇 陈晓璇 王天真 范诺 ABDUL WAHID BALOCH 张荣沭 | 2021 | 森林工程2021，37，4： | 14 |
| 3 | Genotypic Characterization of Methicillin-resistant Staphylococcus aureus Isolated from Pigs and Retail Foods in China显示文摘Objective To investigate the genotypic diversity of Methicillin-resistant Staphylococcus aureus(MRSA) isolated from pigs and retail foods from different geographical areas in China and further to study the routes and rates of transmission of this pathogen from animals to food. Methods Seventy-one MRSA isolates were obtained from pigs and retail foods and then characterized by multi-locus sequencing typing(MLST), spa typing, multiple-locus variable number of tandem repeat analysis(MLVA), pulsed-field gel electrophoresis(PFGE), and antimicrobial susceptibility testing. Results All isolated MRSA exhibited multi-drug resistance(MDR). Greater diversity was found in food-associated MRSA(7 STs, 8 spa types, and 10 MLVA patterns) compared to pig-associated MRSA(3 STs, 1 spa type, and 6 MLVA patterns). PFGE patterns were more diverse for pig-associated MRSA than those of food-associated isolates(40 vs. 11 pulse types). Among the pig-associated isolates, CC9-ST9-t899-MC2236 was the most prevalent clone(96.4%), and CC9-ST9-t437-MC621(20.0%) was the predominant clone among the food-associated isolates. The CC9-ST9 isolates showed significantly higher antimicrobial resistance than other clones. Interestingly, CC398-ST398-t034 clone was identified from both pig-and food-associated isolates. Of note, some community-and hospital-associated MRSA strains(t030, t172, t1244, and t4549) were also identified as food-associated isolates. Conclusion CC9-ST9-t899-MC2236-MDR was the most predominant clone in pigs, but significant genetic diversity was observed in food-associated MRSA. Our results demonstrate the great need for improved surveillance of MRSA in livestock and food and effective prevention strategies to limit MDR-MRSA infections in China. | WANG Wei LIU Feng ZULQARNAIN Baloch ZHANG Cun Shan MA Ke PENG Zi Xin YAN Shao Fei HU Yu Jie GAN Xin DONG Yin Ping BAI Yao LI Feng Qin YAN Xiao Mei MA Ai Guo XU Jin | 2017 | Biomedical and Environmental Sciences2017，30，8： | 13 |
| 4 | 黏虫热休克蛋白Hsp90基因的克隆及不同温度对其诱导反应显示文摘热休克蛋白是昆虫体内一种很重要的抗逆蛋白,Hsp90是热休克蛋白家族中的重要成员。本试验利用高通量测序法获得Hsp90的c DNA的全长序列,通过Real-time PCR探讨黏虫各龄期、组织和黏虫3龄幼虫受到不同高、低温胁迫不同时间的Hsp90基因的相对表达量。在黏虫体内得到Hsp90的c DNA全长序列(Gen Bank登录号MF773751)2422 bp,命名为Ms Hsp90,编码717个氨基酸,分子量约为82.576 ku,等电点是4.98,序列包含有Hsp90的保守序列,与鳞翅目夜蛾科的甜菜夜蛾、苜蓿夜蛾、斜纹夜蛾亲缘关系较近,且氨基酸序列相似性都在98%以上。Real-time PCR结果显示黏虫的不同发育阶段和组织中均有Ms Hsp90表达,其中2龄幼虫和后肠的相对表达量最高。40℃处理6 h的相对表达量最高,处理12、24、48 h时,20℃的相对表达量最高。上述分析可知,Ms Hsp90相对表达量的高低表明在黏虫不同组织,不同发育阶段和不同时间、温度处理中发挥的作用存在差异。 | 杨静 Nasir Ali Baloch 樊东 | 2017 | 中国生物防治学报2017，33，5： | 11 |
| 5 | The Ability of Baseline Triglycerides and Total Cholesterol Concentrations to Predict Incidence of Type 2 Diabetes Mellitus in Chinese Men and Women:A Longitudinal Study in Qingdao, China显示文摘Objectives The purpose of this study was to assess the association between triglycerides(TG),total cholesterol(TC)at baseline,and type 2 diabetes mellitus(T2DM)incidence in a general Chinese population.Further,it aimed to evaluate the ability of TG and TC to predict T2DM incidence.Methods Qingdao Diabetes Prevention Program participants recruited between 2006 and 2009 were followed up in 2012–2015.TG,TC,and T2DM status were measured.Cox proportional hazards models were used to estimate the association between TG,TC,and T2DM incidence.The receiver operating characteristic(ROC)curve was used to evaluate the ability of TG and TC to identify T2DM participants.Results The incidence of T2DM significantly increased with TG in women and TC in both men and women(Ptrend<0.05).Univariate Cox regression indicated that higher TG{borderline high TG[hazards ratio(HR):2.05;95%confidence interval(CI):1.40,3.00]and hypertriglyceridemia[HR:2.64;95%CI:1.68,4.15]}and TC[hypercholesterolemia(HR:2.05;95%CI:1.43,2.95)]were significantly associated with increased risk of T2DM incidence in women but not in men.Multivariate Cox regression showed that hypertriglyceridemia in women(HR:1.78,95%CI:1.07,2.97),borderline high TC in men(HR:1.61,95%CI:1.04,2.48),and hypercholesterolemia in women(HR:1.68,95%CI:1.81,2.61)had a higher significant risk of T2DM incidence.The optimal cutoff values of TG were>1.15 and>1.23 mmol/L in men and women,respectively.For TC,they were>5.17 and>5.77 mmol/L in men and women,respectively.The area under the ROCs of TG and TC were 0.54(0.51–0.57)and 0.55(0.52–0.58),respectively,in men,and 0.60(0.58–0.62)and 0.59(0.56–0.61),respectively,in women.Conclusion Elevated TG and TC were risk factors for T2DM incidence.However,no predictive capacity was found for both factors to identify T2DM incidence in Chinese men and women.Hence,TG and TC levels in both Chinese men and women might be used for decreasing the incidence of T2DM but no clinical predictive capacity for T2DM. | CUI Jing MA Ping SUN Jian Ping Zulqamain Baloch YIN Fan XIN Hua Lei REN Jie TAN Ji Bin WANG Bing Ling | 2019 | Biomedical and Environmental Sciences2019，32，12： | 7 |
| 6 | 木霉对月季幼苗生长的影响显示文摘为了研制促进月季生长的木霉生防菌肥,采用本实验室分离鉴定的哈茨木霉T6施于月季盆栽土壤中,分析木霉菌对“十姐妹”月季硬枝扦插发芽、幼苗生长、防御酶活性和内源激素水平的影响。结果表明:施用哈茨木霉T6的月季硬枝出芽率和幼苗枝条长度分别是对照的1.4和1.82倍;并且枝条和叶的干重、枝条和叶的含水率均显著增加。此外显著提高了叶中3种防御酶SOD、POD、CAT的活性及6种内源激素IAA、GA 3、ZT、ABA、SA和JA的水平。说明木霉T6具有促进月季生长和提高其抗性的作用,研究结果为研制促进月季生长的生物菌肥提供理论依据。 | 邓俊杰 ABDUL MAJEED BALOCH 侯雪月 李嘉哲 茶新有 张荣沭 | 2020 | 植物研究2020，40，5： | 4 |
| 7 | Effect of seedling age and water depth on morphological and physiological aspects of transplanted rice under high temperature显示文摘To study the effect of high temperature, rice seedlings 20, 30, 40 and 50 d were kept at 5, 10, 15 and 20 cm water depth in a water pool. Meteorological findings indicated that water temperature varied up to 10 cm but became stable below this depth. Deep water inflicted higher tiller mortality, minimal increase in dry weight of aerial parts and leaf area, decrease in root length, and decrease in root dry weight especially at 20 cm water depth and produced an unbalanced T/R ratio (top versus root dry weight). However, deep water tended to increase plant length. These parameters, however, excel in shallow water. Older seedlings, with the exception of root dry weight, could not perform well compared to young seedlings in all physiological and morphological aspects. The study revealed that seedlings, particularly young ones, stand well in shallow water and can cope with high temperature. | KHAKWANI Abdul Aziz SHIRAISHI Masaaki ZUBAIR Muhammad BALOCH Mohammad Safdar NAVEED Khalid AWAN Inayatullah | 2005 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2005，6，5： | 4 |
| 8 | Growth and yield of rice as affected by transplanting dates and seedlings per hill under high temperature of Dera Ismail Khan, Pakistan显示文摘Studies were initiated for two consecutive years to find out the effect of time of transplanting and seedlings hill?1 on the productivity of rice in Dera Ismail Khan district of North West Frontier Province (NWFP), Pakistan. The experiment was laid out in a randomized complete block design with split plot arrangements. Main plots consisted of four transplanting dates viz. 20th and 27th of June and 4th and 11th of July while sub-plots contained 1, 2, 3 or 4 seedlings hill?1. Among transplanting dates, June 20th planted crop gave highest paddy yield and net return with 1 seedling hill–1. It explains that the use of more seedlings hill?1 not only adds to cost but is also a mere wastage of natural resources. Based on research findings, we conclude that the use of 1 seedling hill?1 is most appropriate for timely sowing otherwise 4 seedlings hill–1 should be used to compensate for the yield gap in late transplanted rice. | BALOCH Mohammad Safdar AWAN Inayat Ullah HASSAN Gul | 2006 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2006，7，7： | 3 |
| 9 | 小麦矮秆基因Rht-8对株高和其它农艺性状的遗传效应(英文)显示文摘分析矮秆基因Rht-8的遗传力及其对小麦株高及相关农艺性状的影响。利用三个小麦品种晋麦47、西峰20、丰产3号分别与Rht-8的供体亲本济宁13杂交,以其F2分离群体分析Rht-8的遗传效应。结果表明,丰产3号和济宁13后代的遗传力最高(74.32%),西峰20、晋麦47与济宁13后代的遗传力分别为69.49%、67.60%。Rht-8在西峰20和济宁13的F2中具有较强的效应,株高和穗下节分别降低了30.26%和19.20%。在丰产3号和晋麦47与济宁13的F2中,株高和穗下节分别降低了27.14%和26.15%、14.86%和14.59%。Rht-8减少了有效分蘖个数,对其他性状则无明显的不利影响。相关性分析表明株高与分蘖数显著正相关(r为0.415,0.355,0.489),与穗下节显著正相关(r为0.408,0.450,0.500);株高与穗长、每穗小穗数、穗粒数没有显著相关性。 | Baloch Ghulam Asghar 李翠 胡银岗 | 2014 | 干旱地区农业研究2014，32，1： | 3 |
| 10 | 西瓜果肉番茄红素含量及果实相关性状QTL分析显示文摘目的与意义:番茄红素是重要的天然类胡萝卜素,对人体具有保健作用,同时也是红色果肉西瓜中的主要色素,是决定西瓜果实品质的重要因素之一.栽培西瓜较低的DNA多态性阻碍了高质量遗传图谱的构建和番茄红素含量主效QTL的研究.该研究中,笔者成功地利用自行开发的CAPS标记构建了一个包含16个连锁群的西瓜遗传连锁图谱,该图谱将有利于西瓜果肉番茄红素含量关键基因确定及其克隆的进一步研究,同时为西瓜果肉番茄红素含量分子育种提供行之有效的分子标记. | 王超楠 刘识(编译) 高鹏 王学征 Angela R.Davis Abdul Majeed Baloch 栾非时 | 2019 | 中国瓜菜2019，32，8： | 3 |
| 11 | Characteristic spectral studies and in vitro antifungal activity of some Schiff bases and their organotin (Ⅳ) complexes显示文摘The synthesis and in vitro antifungal activity of some Schiff bases and their Sn (Ⅳ) complexes has been tested against plant pathogenic fungi and it is found that they possess excellent fungicidal activity. On the basis of ^1H-, ^13C-,^119Sn NMR-, ^119Sn Mǒssbauer, IR and Elemental analysis the tetrahedral geometry is proposed for the synthesized compounds. | Wajid Rehman Musa Kaleem Baloch Bakhtiar Muhammad Amin Badshah Khalid M.Khan | 2004 | Chinese Science Bulletin2004，49，2： | 3 |
| 12 | 中国30年来新发病毒性传染病与病毒溯源综述显示文摘2019年底,COVID-19在全球暴发,给全人类带来灾难.新发传染病在全球范围内频繁发生、迅速蔓延,由于缺乏有效的应对措施,往往造成严重后果.发现和鉴定病原体是开发新的治疗药物及疫苗的基础,明确病原体来源及其传播途径则是制定防控方案的前提.针对冠状病毒、流感病毒和虫媒病毒等我国30年(1990~2021)来发生的主要传染病流行特点与传播来源进行比较分析,深入阐述了这些新发病原体主要为动物来源,冠状病毒广泛存在于脊椎动物,流感病毒主要在野生鸟类中发现,虫媒病毒主要通过吸血节肢动物在动物和人之间传播.病毒在动物间、动物媒介自然传播,构成病原体自然传播链,在特殊情况下病原体传播给易感者,可能造成人与人之间传播.密切监控病原体在宿主动物的存在与活动状态,与携带传染性病毒的动物保持安全距离,可以最大程度地减少病毒从动物传播给人类的风险.基于'提前预警、主动防御'的客观需求,亟待开展动物携带病原谱调查与传播风险评价,针对性开发预防性疫苗和抗病毒药物,制定切实可行的'未来病毒'防控措施. | 尹建华 BALOCH Zulqarnain 夏雪山 | 2021 | 昆明理工大学学报(自然科学版)2021，46，4： | 3 |
| 13 | Malaria:elimination tale from Yunnan Province of China and new challenges for reintroduction显示文摘Background::Eradication of infectious disease is the sanctified public health and sustainable development goal around the world.Main body::Three antimalarial barriers were developed to control imported malarial cases,and an effective surveillance strategy known as the'1-3-7 approach'was developed to eliminate malaria from the Chinese population.From 2011 to 2019,5254 confirmed malaria cases were reported and treated in Yunnan Province,China.Among them,4566 cases were imported from other countries,and 688 cases were indigenous from 2011 to 2016.Since 2017,no new local malarial case has been reported in China.Thus,malaria has been completely eliminated in Yunnan Province.However,malaria is detected in overseas travellers on a regular basis,such as visitors from neighbouring Myanmar.Conclusion::Hence,the strategies should be further strengthened to maintain a robust public health infrastructure for disease surveillance and vector control programs in border areas.Such programs should be supported technically and financially by the government to avert the possibility of a malarial resurgence in Yunnan Province. | Heng-Lin Yang Zulqarnain Baloch Jian-Wei Xu Xiao-Dong Sun Zu-Rui Lin Yao-Wu Zhou Xiao-Tao Zhao Quan Lv Shi-Yuan Xu Chun-Li Ding Qi-Yan Chen Peng Tian Kai-Xia Dung Xue-Shan Xia Hong-Ning Zhou | 2021 | Infectious Diseases of Poverty2021，10，4： | 3 |
| 14 | Effect of Establishment Methods and Weed Management Practices on Some Growth Attributes of Rice显示文摘Studies were carried out for two years to evaluate the effect of methods of sowing and weed control practices on the productivity of transplanted and direct wet-seeded rice in Dera Ismail Khan, NWFP, Pakistan. The experiment was laid out in a randomized complete block design with a split plot arrangement. The planting techniques viz. transplanting and direct seeding were maintained in main plots while weed control practices included the use of granular herbicide Sunstar 15WG (ethoxy sulfuron), Machete 60EC (butachlor), conventional hand weeding, and the weedy check (control) were assigned to the sub-plots. Data were recorded on weed parameters like weed density and dry weed biomass 60 and 90 days after sowing (DAS); agronomic parameters including plant population, number of panicles and paddy yield and physiological parameters like leaf area index and net assimilation rate 45 and 90 DAS. The planting methods and weed management significantly influenced most of the parameters studied. The data revealed that the paddy yield and its components were significantly higher in the transplanted method than that in direct-seeded method, while the weed density and biomass were lower in the transplanted plots than the direct-seeded plots. Among weed management tools, the maximum paddy yield was obtained in hand weeding, closely followed by herbicide application Machete 60EC during both cropping seasons. | Mohammad Safdar BALOCH Inayat Ullah AWAN Gul HASSAN Abdul Aziz KHAKWANI | 2006 | Rice science2006，13，2： | 2 |
| 15 | Agricultural Extension in Balochistan, Pakistan:Date Palm Farmers' Access and Satisfaction显示文摘This study analyzed information gathered from 200 date palm households in the mountainous Panjgur District of Balochistan in Pakistan with the aim of determining date farmers' access to and satisfaction with agricultural extension services. Information was collected through a structured questionnaire survey, group discussions and semistructured personal interviews. The findings of the analysis revealed very poor access to extension services. The results of logistic regression analysis identified five variables out of six which significantly influence date farmers' access to extension services: household head's age, household head's literacy, number of date palm trees owned, mostly inherited date palm trees, and percentage of dead date palm trees. The overwhelming majority of farmers were dissatisfied with all three main types of extension services being provided by public extension officials. Explanations for this as well as for associations between access to extension services and the six independent variables are provided. Important policy conclusions are drawn based on the findings. | BALOCH A.Mumtaz THAPA B.Gopal | 2014 | Journal of Mountain Science2014，11，4： | 2 |
| 16 | Metabolic investigations in patients with hepatitis B and C显示文摘AIM:To investigate the similarities and dissimilarities in patients with hepatitis B and hepatitis C,clinically and metabolically. METHODS:Fifty patients with hepatitis B virus and hepatitis C virus infection were included in this study, along with fifty healthy controls for comparison purposes.Intravenous blood(10 mL)samples from patients and healthy subjects were collected and made to clot before serum was separated and immediately levels of the enzymes,alkaline phosphatase(ALK),creatinine phosphokinase(CPK),lactate dehydrogenase (LDH),serum glutamate oxaloacetate transaminase(sGOT)and serum glutamate pyruvate transaminase(sGPT)were determined by a kit method.For total con-tent of each metal the serum samples were analyzed using atomic absorption spectrophotometry.Levels of cholesterol,triglycerides,urea,creatinine and uric acid were determined using a kit method on Microlab 300. RESULTS:Serum magnesium and copper levels remained unchanged,whereas the concentration of zinc decreased and iron increased significantly in both groups of patients.Total antioxidant activity was significantly decreased in both hepatitis B and C.Among the enzymes analyzed,ALK,s-GPT,LDH and s-GOT were all significantly increased in both patients with hepatitis B and C whereas CPK was significantly decreased in patients with hepatitis B and remained unchanged in patients with hepatitis C. CONCLUSION:The information accumulated by this study will help provide a better understanding of involved metabolic processes in order to design appropriate therapeutic approaches for treating these patients,so they can recover and lead normal lives. | Abdul Aziz Mastoi Bikha Ram Devrajani Syed Zulfiquar Ali Shah Qasim Rohopoto Sikander Ali Memon Marya Baloch Ghulam Ali Qureshi Waqas Sami | 2010 | World Journal of Gastroenterology2010，16，5： | 2 |
| 17 | Evaluation of the fishery status for King Soldier Bream Argyrops spinifer in Pakistan using the software CEDA and ASPIC显示文摘Catch and effort data were analyzed to estimate the maximum sustainable yield(MSY) of King Soldier Bream, Argyrops spinifer(Forssk?l, 1775, Family: Sparidae), and to evaluate the present status of the fish stocks exploited in Pakistani waters. The catch and effort data for the 25-years period 1985–2009 were analyzed using two computer software packages, CEDA(catch and effort data analysis) and ASPIC(a surplus production model incorporating covariates). The maximum catch of 3 458 t was observed in 1988 and the minimum catch of 1 324 t in 2005, while the average annual catch of A. spinifer over the 25 years was 2 500 t. The surplus production models of Fox, Schaefer, and Pella Tomlinson under three error assumptions of normal, log-normal and gamma are in the CEDA package and the two surplus models of Fox and logistic are in the ASPIC package. In CEDA, the MSY was estimated by applying the initial proportion(IP) of 0.8, because the starting catch was approximately 80% of the maximum catch. Except for gamma, because gamma showed maximization failures, the estimated results of MSY using CEDA with the Fox surplus production model and two error assumptions, were 1 692.08 t(R 2 =0.572) and 1 694.09 t( R 2 =0.606), respectively, and from the Schaefer and the Pella Tomlinson models with two error assumptions were 2 390.95 t( R 2 =0.563), and 2 380.06 t( R 2 =0.605), respectively. The MSY estimated by the Fox model was conservatively compared to the Schaefer and Pella Tomlinson models. The MSY values from Schaefer and Pella Tomlinson models were the same. The computed values of MSY using the ASPIC computer software program with the two surplus production models of Fox and logistic were 1 498 t(R 2 =0.917), and 2 488 t( R 2 =0.897) respectively. The estimated values of MSY using CEDA were about 1 700–2 400 t and the values from ASPIC were 1 500–2 500 t. The estimates output by the CEDA and the ASPIC packages indicate that the stock is overfished, and needs some effective management to reduce the fishing effort of the species in Pakistani waters. | Aamir Mahmood MEMON 刘群 Khadim Hussain MEMON Wazir Ali BALOCH Asfandyar MEMON Abdul BASET | 2015 | Chinese Journal of Oceanology and Limnology2015，33，4： | 2 |
| 18 | Carbon and nitrogen removal ina granular bed baffled reactor 显示文摘 | Baloch M I Akunna J C Collier P J | 2006 | Environmental Technology2006，27，2： | 1 |
| 19 | Distribution and diversity of hepatitis B virus genotypes in Yunnan, China显示文摘 | Binghui Wang Yue Feng Zheng Li Haiping Duan Ting Zhao Amei Zhang Li Liu Zulqarnain Baloch Xueshan Xia | 2014 | Virol2014，，10： | 1 |
| 20 | The performance of a phase separated granular bed bioreactor treating brewery wastewater 显示文摘 | BALOCH M I AKUNNA J C COLLIER P J | 2007 | Bioresource Technology2007，98，： | 1 |
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