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3篇 您的检索式:作者名="Bailu Zhang"
    题名 作者 年代 出处 被引量
1Somatic copy number alterations are predictive of progression-free survival in patients with lung adenocarcinoma undergoing radiotherapy显示文摘Objective:Lung cancer is the most common cause of cancer-related deaths worldwide.Somatic copy number alterations(SCNAs)have been used to predict responses to therapies in many cancers,including lung cancer.However,little is known about whether they are predictive of radiotherapy outcomes.We aimed to understand the prognostic value and biological functions of SCNAs.Methods:We analyzed the correlation between SCNAs and clinical outcomes in The Cancer Genome Atlas data for 486 patients with non-small cell lung cancer who received radiotherapy.Gene set enrichment analyses were performed to investigate the potential mechanisms underlying the roles of SCNAs in the radiotherapy response.Our results were validated in 20 patients with lung adenocarcinoma(LUAD)receiving radiotherapy.Results:SCNAs were a better predictor of progression-free survival(PFS)in LUAD(P=0.024)than in lung squamous carcinoma(P=0.18)in patients treated with radiotherapy.Univariate and multivariate regression analyses revealed the superiority of SCNAs in predicting PFS in patients with LUAD.Patients with stage I cancer and low SCNA levels had longer PFS than those with high SCNA levels(P=0.022).Our prognostic nomogram also showed that combining SCNAs and tumor/node/metastasis provided a better model for predicting long-term PFS.Additionally,high SCNA may activate the cell cycle pathway and induce tumorigenesis.Conclusions:SCNAs may be used to predict PFS in patients with early-stage LUAD with radiotherapy,in combination with TNM,with the aim of predicting long-term PFS.Therefore,SCNAs are a novel predictive biomarker for radiotherapy in patients with LUAD.Fan Kou Lei Wu Yan Guo Bailu Zhang Baihui Li Ziqi Huang Xiubao Ren Lili Yang 2022Cancer Biology & Medicine2022,19,5:1
2Pervaporationpropertiesandcharacterizationofpoly(vinylalcohol)/cellulosenanocrystalcompositemembranes显示文摘BaiLu Zhang Liping Qu Ping etal 2011ChemiGcalJournalofChineseUniversities2011,,4:1
3Underpotential Deposition Preparation of Pt-loading AuNPs/Reduced Graphene Oxide and Its Catalytic Detection of Catechol显示文摘Ultralow 装载磅的 Au nanoparticles 被使用 underpotential 在减少的 graphene 氧化物(RGO ) 的表面上制作了免职(UPD ) 单层氧化还原作用代替过程。Pt/Au/RGO 修改了电极展览向儿茶酚和对苯二酚的一项优秀 electrocatalytic 活动。在优化条件下面,在对苯二酚和儿茶酚之间的 peak-to-peak 的分离是 197 mV,它是足够宽的区分 benzenediol 的异构体。儿茶酚被 Pt/Au/RGO/GCE 面对对苯二酚与低察觉限制检测。Cong Wang Zhihua Guo Li Zhang Na Zhang Keying Zhang Bailu Fei Hongyan Wang Jigui Xu Hongwei Shi Miao Qin Lei Ren Xingxing Wu 2016Chinese Journal of Chemistry2016,34,11:0
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