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73篇 您的检索式:作者名="BURK RF"
    题名 作者 年代 出处 被引量
1中国成人硒需要量研究显示文摘目的探讨使人体血浆硒蛋白P(SEPP1)达到饱和的硒摄入量,以评估硒需要量,为膳食硒参考摄入量DRIs的修订提供参考。方法对98名低硒健康受试者(体重平均58kg)进行为期40w的双盲补硒实验。随机分为七组,补硒(以硒蛋氨酸形式)剂量分别为0、21、35、55、79、102和125μg/d。定期检测血浆中谷胱甘肽过氧化物酶(GPX3)活性、SEPP1含量和硒含量等硒状态功能指标。选择剂量响应曲线的饱和平台起始点的相应摄入量作为该指标的需要量。结果在实验40w时,使血浆SEPP1含量达到饱和的硒摄入量为49μg/d;使血浆GPX3活性达到饱和的硒摄入量为35μg/d;血浆硒不能达到饱和平台,故不能用来作为评价硒需要量的指标。结论就当前人体实验而言,血浆SEPP1含量是反映硒营养状态和测定硒需要量的最佳指标。所以,满足SEPP1合成的硒摄入量49μg/d,经体重和个体变异等因素适当调节后,可作为人体硒需要量和修订膳食硒参考摄入量DRIs的参考。夏弈明 KE Hill 李平 徐家沅 周定友 RF Burk 2011营养学报2011,33,2:25
2Biochemical studies of a selenium-deficient population in China: measurement of selenium, glutathione peroxidase and oxidant defenses in blood 显示文摘Xia Y Hill KE and Burk RF 1989J Nutr1989,119,:1
3Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeosta?sis 显示文摘Burk RF Hill KE 2005Annu Rev Nutr2005,25,1:1
4Effects of chemical form of selenium on plasma biomarkers in a high-dose human supplementation trial显示文摘Burk RF Norsworthy BK Hill KE 2006Cancer Epidemiol Biomarkers Prev2006,15,:1
5Selenium, an antioxidant nutrient 显示文摘Burk RF 2002Nutr Clin Care2002,5,2:1
6Determination of thioredoxin reductase activity in rat liver supernatant显示文摘Hill KE Me Collum GW Burk RF 1997Anal Biochem1997,253,2:1
7Deletion of selenoprotein P upregulates urinary selenium excretion and depresses whole-body selenium content 显示文摘Burk RF Hill KE Motley AK 2006Biochim Biophys Acta2006,1760,:1
8Deletion of selenoprotein P upregulates urinary selenium excretion and depresses whole-body selenium content 显示文摘Burk RF Hill KE Motley AK 2006Biochim Biophys Acta2006,1760,12:1
9Plasma, Selenium in pa- tients with eirrhosis显示文摘Burk RF Early DS Hill KE 1998Hepatology1998,23,3:1
10Purification of selenoprotein P from human plasma显示文摘Akesson B Bellew T Burk RF 1994Biochim Biophys Acta1994,1204,2:1
11Production of Selenium deficiency in the rat显示文摘Burk RF 1987MethodsEnzymol1987,143,:1
12Biochemical studies of a selenium- deficient population in China, Measurement of selenium,glutathione peroxidase and other oxidant defense indices inblood显示文摘Xia YM Hill KE Burk RF 1989J Nutr1989,119,9:1
13Differential functions of the Apoer2 intracellular domain in selenium uptake and cell signal?ing 显示文摘Masiulis I Quill TA Burk RF 2009Bioi Chem2009,390,1:1
14Glutathione peroxidase- 3 produced by the kidney binds to a population of basement membranes in the gastrointestinal tract and in other tissues显示文摘Burk RF O/son GE Winfrey VP 2011Am J Physiol Gastrointest Liver Physiol2011,301,1:1
15Glutathione peroxidase activity in sele-nium-deifcient rat liver显示文摘Lawrence RA Burk RF 0,,:1
16Carbon tetrachloride hepatotoxicity: an example of free radical - mediated injury 显示文摘Williams AT Burk RF 1990Semin Liver Dis1990,10,4:1
17Orphan selenoproteins 显示文摘Burk RF Hill KE 1999Bioessays1999,21,3:1
18Biological activity of selenium显示文摘Burk RF 1983Annu Rev Nutr1983,3,:1
19Selenium recent clinical advances显示文摘Burk RF 2001Curr Opin Gastroonterol2001,17,:1
20A prospective study of plasma selenoprotein P and lung cancer risk among low -in- come adults显示文摘EPPLEIN M BURK RF CAI Q 2014Cancer Epidemiol Biomarkers Prev2014,23,7:1
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