|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Laparoscopic natural orifice specimen extraction-colectomy: A systematic review显示文摘Over the last 20 years, laparoscopic colorectal surgery has shown equal efficacy for benign and malignant colorectal diseases when compared to open surgery. However, a laparoscopic approach reduces postoperative morbidity and shortens hospital stay. In the quest to optimize outcomes after laparoscopic colorectal surgery, reduction of access trauma could be a way to improve recovery. To date, one method to reduce access trauma is natural orifice specimen extraction(NOSE). NOSE aims to reduce access trauma in laparoscopic colorectal surgery. The specimen is delivered via a natural orifice and the anastomosis is created intracorporeally. Different methods are used to extract the specimen and to create a bowel anastomosis. Currently, specimens are delivered transcolonically, transrectally, transanally, or transvaginally. Each of these NOSEprocedures raises specific issues with regard to operative technique and application. The presumed benefits of NOSE-procedures are less pain, lower analgesia requirements, faster recovery, shorter hospital stay, better cosmetic results, and lower incisional hernia rates. Avoidance of extraction site laparotomy is the most important characteristic of NOSE. Concerns associated with the NOSE-technique include bacterial contamination of the peritoneal cavity, inflammatory response, and postoperative outcomes, including postoperative pain and the functional and oncologic outcomes. These issues need to be studied in prospective randomized controlled trials. The aim of this systematic review is to describe the role of NOSE in minimally invasive colorectal surgery. | Albert M Wolthuis Anthony de Buck van Overstraeten André D'Hoore | 2014 | World Journal of Gastroenterology2014，20，36： | 65 |
| 2 | Catalytic domain of PDC-E2 contains epitopes recognized by antimitochondrial antibodies in primary biliary cirrhosis显示文摘AIM:To search for further immunodominant peptides of the pyruvate dehydrogenase complex E2-component (PDC-E2) recognized by antimitochondrial antibodies (AMA) in primary biliary cirrhosis (PBC). METHODS:Sera from 95 patients with PBC were tested by enzyme-linked immunosorbent assay against 33 synthetic overlapping peptides (25 amino acids; aa) covering the entire length of the E2-subunit of PDC-E2. Furthermore,the inner lipoyl peptide 167-184 was used in an unlip oylated and a lipoylated form as well as coupled to ovalbumin. Sera from 11 AMA negative/ANA posit ive PBC patients,63 patients with other liver disorders and 22 healthy blood donors served as controls.RESULTS:Of the 95 PBC-sera,74% reacted with the peptide 475-499 and 58% with the pept ide 407-431 located within the catalytic domain of PDC-E2. Patients with other disorders or healthy controls were positive in only up to 18%. Antibodies to the unlipoylatedand lip oylated pept ide 167-184 within the inner lipoyl domain were found in only 5% and 11% of the PBC sera,respectively; using ovalbumin-coupled peptides,the incidence increased up to 57% (unlipoylated form). CONCLUSION:Peptides within the catalytic site of PDC-E2 rather than the previously reported lipoyl binding peptide 167-184 may represent major immunodomin ant epitopes recognized by AMA in PBC. | Sandra Braun Christoph Berg Sandra Buck Michael Gregor Reinhild Klein | 2010 | World Journal of Gastroenterology2010，16，8： | 13 |
| 3 | Mechanical thrombectomy in patients with M1 occlusion and NIHSS score≤5:a single-centre experience显示文摘Background:The recent success of several mechanical thrombectomy trials has resulted in a significant change in management for patients presenting with stroke.However,it is still unclear how to manage patients that present with stroke and low National Institutes of Health Stroke Scale(NIHSS)≤5.We sought to review our experience of mechanical thrombectomy in patients with low NIHSS and confirmed M1 occlusion.Methods:We retrospectively analysed our prospectively maintained database of all patients undergoing mechanical thrombectomy between January 2008 and August 2016.We identified 41 patients with confirmed M1 occlusion and low NIHSS(≤5)on admission to our hospital.We collected demographic,radiological,procedural and outcome data.Results:The mean age of patients was 72±14,with 20 male patients.Associated medical conditions were common with hypertension seen in∼80%.Just over 50%presented with NIHSS 4 or 5.The average ASPECTS score on admission was 8.8(range 6–10),and the average clot length 10 mm.Angiographically Thrombolysis in Cerebral Infarction(TICI)≥2b was obtained in 87.8%of patients.7 patients had haemorrhage on follow-up,2 of which were symptomatic.Of 40 patients with 90-day follow-up,75%had modified Rankin Scale(mRS)score 0–2.There were 3 deaths at 90 days.Conclusions:Mechanical thrombectomy in patients with low NIHSS and proximal large vessel occlusion is technically possible and carries a high degree of success with good safety profile.Patients with low NIHSS and confirmed occlusion should be considered for mechanical thrombectomy. | P Bhogal P Bucke O Ganslandt H Bazner H Henkes M Aguilar Perez | 2016 | Stroke & Vascular Neurology2016，1，4： | 9 |
| 4 | Transanal total mesorectal excision:Towards standardization of technique显示文摘AIM: To describe the role of Transanal total mesorectal excision(Ta TME) in minimally invasive rectal cancer surgery, to examine the differences in patient selection and in reported surgical techniques and their impactson postoperative outcomes and to discuss the future of Ta TME. METHODS: MEDLINE(Pub Med), EMBASE, and The Cochrane Library were systematically searched through the 1st of March 2015 using a predefined search strategy. RESULTS: A total of 20 studies with 323 patients were included. Most studies were single-arm prospective studies with fewer than 100 patients. Multiple transanal access platforms were used, and the laparoscopic approach was either multi- or single port. The procedure was initiated transanally or transabdominally. If a simultaneous approach with 2 operating surgeons was chosen, the operative time was significantly reduced. CONCLUSION: Ta TME was also associated with better TME specimens and a longer distal resection margin. Ta TME is thus feasible in expert hands, but the learning curve and safety profile are not well defined. Longterm follow-up regarding anal function and oncological outcomes should be performed in the future. | Albert M Wolthuis Gabriele Bislenghi Anthony de Buck van Overstraeten André D'Hoore | 2015 | World Journal of Gastroenterology2015，21，44： | 9 |
| 5 | Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process显示文摘Aging is a dynamic and progressive process that begins at conception and continues until death.This process leads to a decrease in homeostasis and morphological,biochemical and psychological changes,increasing the individual’s vulnerability to various diseases.The growth in the number of aging populations has increased the prevalence of chronic degenerative diseases,impairment of the central nervous system and dementias,such as Alzheimer’s disease,whose main risk factor is age,leading to an increase of the number of individuals who need daily support for life activities.Some theories about aging suggest it is caused by an increase of cellular senescence and reactive oxygen species,which leads to inflammation,oxidation,cell membrane damage and consequently neuronal death.Also,mitochondrial mutations,which are generated throughout the aging process,can lead to changes in energy production,deficiencies in electron transport and apoptosis induction that can result in decreased function.Additionally,increasing cellular senescence and the release of proinflammatory cytokines can cause irreversible damage to neuronal cells.Recent reports point to the importance of changing lifestyle by increasing physical exercise,improving nutrition and environmental enrichment to activate neuroprotective defense mechanisms.Therefore,this review aims to address the latest information about the different mechanisms related to neuroplasticity and neuronal death and to provide strategies that can improve neuroprotection and decrease the neurodegeneration caused by aging and environmental stressors. | Mariana Toricelli Arthur Antonio Ruiz Pereira Guilherme Souza Abrao Helena Nascimento Malerba Julia Maia Hudson Sousa Buck Tania Araujo Viel | 2021 | Neural Regeneration Research2021，16，1： | 8 |
| 6 | 基于Autoform的汽车侧围回弹补偿分析显示文摘目的针对汽车尤其乘用车侧围大量复杂表面经常出现的表面凹陷、大尺寸回弹等质量问题,对回弹过程进行分析研究并加以控制。方法基于数值模拟的方法,采用Autoform软件对汽车侧围表面冲压回弹进行数值模拟预测,将数值计算结果与实际生产经验相结合,对侧围几何模型进行补偿和控制。结果生产的后侧围零件尺寸合格率达到90%以上。结论采用数值模拟对汽车侧围回弹补偿分析,能减少成形过程中的缺陷,提高尺寸精度,有效解决侧围回弹大的问题。 | 韦韡 姚佐平 李开文 张峰 Hans-Ludwig Buck 周江奇 | 2021 | 精密成形工程2021，13，3： | 8 |
| 7 | Chimeric dopamine-norepinephrine transporters delineste structural domains influencing selectivity for catecholamine and 1-methyl-4-phenylpyridinium 显示文摘 | Buck KJ Amara SG | 1994 | Proc Natl Acad Sci USA1994，91，12： | 6 |
| 8 | Estimation of particle dynamics in 2-D fluidized beds using particle tracking velocimetry显示文摘The experimental characterization of particle dynamics in fluidized beds is of great importance in fostering an understanding of solid phase motion and its effect on particle properties in granulation processes.Commonly used techniques such as particle image velocimetry rely on the cross-correlation of illumination intensity and averaging procedures.It is not possible to obtain single particle velocities with such techniques.Moreover,the estimated velocities may not accurately represent the local particle velocities in regions with high velocity gradients.Consequently,there is a need for devices and methods that are capable of acquiring individual particle velocities.This paper describes how particle tracking velocimetry can be adapted to dense particulate flows.The approach presented in this paper couples high-speed imaging with an innovative segmentation algorithm for particle detection,and employs the Voronoi method to solve the assignment problem usually encountered in densely seeded flows.Lagrangian particle tracks are obtained as primary information,and these serve as the basis for calculating sophisticated quantities such as the solid-phase flow field,granular temperature,and solid volume fraction.We show that the consistency of individual trajectories is sufficient to recognize collision events. | Thomas Hagemeier Christoph Roloff Andreas Buck Evangelos Tsotsas | 2015 | Particuology2015，13，5： | 5 |
| 9 | RECENT ADVANCES IN RESEARCH AND FORECASTING OF TROPICAL CYCLONE TRACK, INTENSITY, AND STRUCTURE AT LANDFALL显示文摘This review prepared for the fourth International Workshop on Tropical Cyclone Landfall Processes(IWTCLP-4) summarizes the most recent(2015-2017) theoretical and practical knowledge in the field of tropical cyclone(TC) track, intensity, and structure rapid changes at or near landfall. Although the focus of IWTCLPIV was on landfall, this summary necessarily embraces the characteristics of storms during their course over the ocean prior to and leading up to landfall. In the past few years, extremely valuable observational datasets have been collected for TC forecasting guidance and research studies using both aircraft reconnaissance and new geostationary or low-earth orbiting satellites at high temporal and spatial resolution. Track deflections for systems near complex topography such as that of Taiwan and La Réunion have been further investigated, and advanced numerical models with high spatial resolution necessary to predict the interaction of the TC circulation with steep island topography have been developed. An analog technique has been designed to meet the need for longer range landfall intensity forecast guidance that will provide more time for emergency preparedness. Probabilistic track and intensity forecasts have also been developed to better communicate on forecast uncertainty. Operational practices of several TC forecast centers are described herein and some challenges regarding forecasts and warnings for TCs making landfall are identified. This review concludes with insights from both researchers and forecasters regarding future directions to improve predictions of TC track, intensity, and structure at landfall. | MARIE-DOMINIQUE LEROUX KIMBERLY WOOD RUSSELL L.ELSBERRY ESPERANZA O.CAYANAN ERIC HENDRICKS MATTHEW KUCAS PETER OTTO ROBERT ROGERS BUCK SAMPSON ZIFENG YU | 2018 | Tropical Cyclone Research and Review2018，7，2： | 4 |
| 10 | Surgery for Crohn's disease in the era of biologicals:A reduced need or delayed verdict?显示文摘Crohn's disease(CD) is a chronic inflammatory bowel disease that can affect the entire gastrointestinal tract.Ultimately,up to 70% of all patients will need surgery,despite optimized medical therapy.Moreover,about half of the patients will need redo-surgery because of disease recurrence.The introduction of anti-tumor necrosis factor(TNF) drugs(Infliximab in 1998) revolutionized the treatment of CD.Different randomized trials assessed the efficacy of anti-TNF treatment not only to induce,but also to maintain,steroid-free remission.Furthermore,these agents can rapidly lead to mucosal healing.This aspect is important,as it is a major predictor for long-term disease control.Subgroup analyses of responding patients seemed to suggest a reduction in the need for surgery at median-term follow up(1-3 years).However if one looks at population surveys,one does not observe any decline in the need for surgery since the introduction of Infliximab in 1998.The short follow-up term and the exclusion of patients with imminent surgical need in the randomized trials could bias the results.Only 60% of patients respond to induction of anti-TNF therapy,moreover,some patients will actually develop resistance to biologicals.Many patients are diagnosed when stenosing disease has already occurred,obviating the need for biological therapy.In a further attempt to change the actual course of the disease,top down strategies have been progressively implemented.Whether this will indeed obviate surgery for a substantial group of patients remains unclear.For the time being,surgery will still play a pivotal role in the treatment of CD. | Anthony de Buck van Overstraeten Albert Wolthuis André D'Hoore | 2012 | World Journal of Gastroenterology2012，18，29： | 4 |
| 11 | Characterization of HULC, a Novel Gene With Striking Up-Regulation in Hepatocellular Carcinoma, as Noncoding RNA显示文摘 | Katrin Panzitt Marisa M.O. Tschernatsch Christian Guelly Tarek Moustafa Martin Stradner Heimo M. Strohmaier Charles R. Buck Helmut Denk Renée Schroeder Michael Trauner Kurt Zatloukal | 2007 | Gastroenterology2007，，1： | 4 |
| 12 | Innovation performance and channels for international technology spillovers: Evidence from Chinese high-tech industries显示文摘 | Xiaohui Liu Trevor Buck | 2007 | Research Policy2007，，3： | 4 |
| 13 | Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients显示文摘Background:The response to neoadjuvant chemotherapy(NAC)differs substantially among individual patients with non-small cell lung cancer(NSCLC).Major pathological response(MPR)is a histomorphological read-out used to assess treatment response and prognosis in patientsNSCLC afterNAC.Although spatial metabolomics is a promising tool for evaluating metabolic phenotypes,it has not yet been utilized to assess therapy responses in patients with NSCLC.We evaluated the potential application of spatial metabolomics in cancer tissues to assess the response to NAC,using a metabolic classifier that utilizes mass spectrometry imaging combined with machine learning.Methods:Resected NSCLC tissue specimens obtained after NAC(n=88)were subjected to high-resolution mass spectrometry,and these data were used to develop an approach for assessing the response to NAC in patients with NSCLC.The specificities of the generated tumor cell and stroma classifiers were validated by applying this approach to a cohort of biologically matched chemotherapy-naive patients with NSCLC(n=85).Results:The developed tumor cell metabolic classifier stratified patients into different prognostic groups with 81.6%accuracy,whereas the stroma metabolic classifier displayed 78.4%accuracy.By contrast,the accuracies of MPR and TNM staging for stratification were 62.5%and 54.1%,respectively.The combination of metabolic and MPR classifiers showed slightly lower accuracy than either individual metabolic classifier.In multivariate analysis,metabolic classifiers were the only independent prognostic factors identified(tumor:P=0.001,hazards ratio[HR]=3.823,95%confidence interval[CI]=1.716-8.514;stroma:P=0.049,HR=2.180,95%CI=1.004-4.737),whereasMPR(P=0.804;HR=0.913;95%CI=0.445-1.874)and TNM staging(P=0.078;HR=1.223;95%CI=0.977-1.550)were not independent prognostic factors.Using Kaplan-Meier survival analyses,both tumor and stroma metabolic classifiers were able to further stratify patients as NAC responders(P<0.001)and non-responders(P<0.001).Conclusions:Our findings indicate that the metabolic constitutions of both tumor cells and the stroma are valuable additions to the classical histomorphology-based assessment of tumor response. | Jian Shen Na Sun Philipp Zens Thomas Kunzke Achim Buck Verena M.Prade Jun Wang Qian Wang Ronggui Hu Annette Feuchtinger Sabina Berezowska Axel Walch | 2022 | Cancer Communications2022，42，6： | 3 |
| 14 | 故宫藏乾隆朝漆纱隔心工艺探究显示文摘故宫乾隆花园符望阁一层明间南向宝座的栏杆罩镶嵌着一组精美绝伦貌如金纱窗的漆纱隔心。类似的隔扇装修不仅在故宫,甚至全国范围内也是独一无二的。符望阁保护修复过程中,发现漆纱隔心存在损毁严重、工艺失传、复制难度大等问题。为对该组漆纱进行研究,运用剖面显微分析、扫描电镜与能谱仪分析、显微红外光谱及多种色谱-质谱联用等实验室科技手段,明确了漆纱由内而外'织物纱芯-双面贴纸样-双面上漆贴金-双面纸样上施绘'四层基本结构关系,以及单侧14个亚层所用的无机、有机材料,为漆纱的保护和复制提供了科学依据。 | 李越 包嫒迪 BUCK Susan LLUVERAS-TENORIO Anna TAMBURINI Diego DEGANO Ilaria COLOMBINI Maria Perla | 2019 | 文物保护与考古科学2019，31，1： | 3 |
| 15 | 带长尖角的乘用车翼子板冲压成形显示文摘针对带长尖角的乘用车翼子板,分析了其表面曲率变化,尤其是主特征附近的曲面变化特征,提出以曲面长高比作为判断曲面变化程度的指标。通过数值模拟的方法,分析翼子板成形性问题,并调整工艺补充和拉延筋,以控制滑移线流动方向,抑制表面质量缺陷的产生。整形面不等高以及V形特征会导致整形过程产生折叠,通过调整支架安装结构、增加工艺缺口,可消除该缺陷。翼子板尖角在冲压过程中易失稳,导致扭曲和回弹,通过对工艺数模进行补偿,可将公差控制在±0.5 mm之内。试验验证结果表明,翼子板实际零件尺寸合格率达到92%,A面和关键匹配面表面光顺平整,质量较好。 | 沈云啸 李恒佰 李开文 张峰 Hans-Ludwig Buck 周乐育 韦韡 | 2021 | 锻压技术2021，46，1： | 3 |
| 16 | Direct isolation of human central nervous system stem cells显示文摘 | Uchida N Buck DW He D | | 0，，： | 2 |
| 17 | Chinese economic development, the next stage: outward FDI?显示文摘 | Xiaohui Liu Trevor Buck Chang Shu | 2004 | International Business Review2004，，1： | 2 |
| 18 | Novel inflammatory biomarkers of portal pressure in compensated cirrhosis patients显示文摘 | Martina Buck Guadalupe Garcia‐Tsao Roberto J. Groszmann Caitlin Stalling Norman D. Grace Andrew K. Burroughs David Patch Daniel S. Matloff Paul Clopton Mario Chojkier | 2014 | Hepatology2014，，3： | 2 |
| 19 | Experimental study and modeling of particle drying in a continuously-operated horizontal fluidized bed显示文摘 | Kaicheng Chen Philipp Bachmann Andreas Buck Michael Jacob Evangelos Tsotsas | 2017 | Particuology2017，15，5： | 2 |
| 20 | 保护区保护覆盖范围的全球化和多维发展趋势(1980~2000)显示文摘本文主要研究1980~2000年期间全球范围内保护区范围的扩张。我们从4个基本方面研究这种多尺度的扩张格局:①世界区域和国家尺度上保护区总覆盖面积增加的估计;②跨边界保护区;③保护廊道计划;④保护区管理类型。保护区的地理空间格局体现了全球保护组织的保护重点和后冷战时期政治经济部署的全球化趋势。地区和国家水平上的因素(政治领导及其制度设置)以及多边和双边援助等国际关系与这些全球化的过程结合起来影响保护区设立的范围、类型和位置。我们认为,在1980~2000年的保护区扩张过程中,这些因素相互作用产生并加强了明显的空间差异(而不是世界范围内的平均化、均质化趋势)。 | Karl S. Zimmerer Ryan E. Galt Margaret V. Buck 王新建(译) 周立志(校) | 2004 | AMBIO-人类环境杂志2004，33，B12： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员