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| 1 | Prediction of delayed graft function using different scoring algorithms: A single-center experience显示文摘AIM To compare the performance of 3 published delayed graftfunction(DGF) calculators that compute the theoretical risk of DGF for each patient.METHODS This single-center,retrospective study included 247 consecutive kidney transplants from a deceased donor.These kidney transplantations were performed at our institution between January 2003 and December 2012.We compared the occurrence of observed DGF in our cohort with the predicted DGF according to three different published calculators. The accuracy of the calculators was evaluated by means of the c-index(receiver operating characteristic curve).RESULTS DGF occurred in 15.3% of the transplants under study.The c index of the Irish calculator provided an area under the curve(AUC) of 0.69 indicating an acceptable level of prediction,in contrast to the poor performance of the Jeldres nomogram(AUC = 0.54) and the Chapal nomogram(AUC = 0.51). With the Irish algorithm the predicted DGF risk and the observed DGF probabilities were close. The mean calculated DGF risk was significantly different between DGF-positive and DGF-negative subjects(P < 0.0001). However,at the level of the individual patient the calculated risk of DGF overlapped very widely with ranges from 10% to 51% for recipients with DGF and from 4% to 56% for those without DGF.The sensitivity,specificity and positive predictive value of a calculated DGF risk ≥ 30% with the Irish nomogram were 32%,91% and 38%. CONCLUSION Predictive models for DGF after kidney transplantation are performant in the population in which they were derived,but less so in external validations. | Magda Michalak Kristien Wouters Erik Fransen Rachel Hellemans Amaryllis H Van Craenenbroeck Marie M Couttenye Bart Bracke Dirk K Ysebaert Vera Hartman Kathleen De Greef Thiery Chapelle Geert Roeyen Gerda Van Beeumen Marie-Paule Emonds Daniel Abramowicz Jean-Louis Bosmans | 2017 | World Journal of Transplantation2017，7，5： | 3 |
| 2 | The tumor ecosys- tem regulates the roads for invasion and metastasis显示文摘 | Hendrix A Gespach C Bracke M | 2011 | Clin Res Hepatol Gastroenterol2011，35，11： | 1 |
| 3 | Pharmacogenetics of drug - induced arrhythmias: a feasibility study using spontaneous adverse drug reactions reporting data显示文摘 | De Bruin ML van Puijenbroek EP Bracke M | 2006 | Pharmacoepidemiol Drug Saf2006，15，2： | 1 |
| 4 | The cerebral expression of plasma protein genes in different species显示文摘 | Aldred A R Brack C M Schreiber G | 1995 | Comp Biochem Physiol B Biochem Mol Biol1995，111，1： | 1 |
| 5 | Extracellular cleavage and shedding of P-cadherin: amechanism underlying the invasive behaviour of breast cancercells显示文摘 | Ribeiro AS Albergaria A Sousa B Correia AL Bracke M SerucaU | 2010 | Oncogene2010，29，39： | 1 |
| 6 | Cancer metastasis: negative regulation by an invasion - suppressor complex 显示文摘 | Mareel M Bracke M Van Roy F | 1995 | Cancer Detect Prey1995，19，5： | 1 |
| 7 | Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography显示文摘 | MAUBACH J BRACKE M E HEYERICK A | 2003 | J Chromatogr B2003，784，1： | 1 |
| 8 | Microsatellite polymorphisms reveal phylogenetic relationships in primates显示文摘 | MEYER E WIEGAND P RAND S P KUHLMANN D BRACK M BRINKMANN B | 1995 | Journal of Molecular Evolution1995，41，： | 1 |
| 9 | The physics of simple metal clusters:self-consistent jellium model and semiclassical approaches显示文摘 | BRACK M | 1993 | Rev Mod Phys1993，65，3： | 1 |
| 10 | Use of beta-2 agonists and risk of hip/ femur fracture: a population-based case-control study 显示文摘 | Pouwels S Bracke M | 2007 | Pharmacoepidemiol Drug Saf2007，66，6： | 1 |
| 11 | Increased Wnt Sig- naling During Aging Alters Muscle Stem Cell Fate and In- creases Fibrosis 显示文摘 | Brack AS Conboy M J Roy S | 2007 | Science2007，317，5839： | 1 |
| 12 | Cancer metastasis: negative regulation by an invasion - suppressor complex 显示文摘 | Mareel M Bracke M Van Roy F | 1995 | Cancer Detect Prey1995，19，5： | 1 |
| 13 | Effect of protein com- position and homogenisation on the stability of acidified milk drinks 显示文摘 | Sedlmeyer F Brack M Rademacher B | 2004 | International Dairy Joumal2004，14，4： | 1 |
| 14 | Design, construction, and characterization of a large synthetic human antibody phage display library 显示文摘 | Silacci M Brack S Schirru G | 2005 | Proteomics2005，5，： | 1 |
| 15 | N-cadherin in the spotlight of cell-cell adhesion, differentiation embryogenesis, invasion and signaling 显示文摘 | Derycke L D Bracke M E | 2004 | IntJDevBiol2004，48，56： | 1 |
| 16 | Experimental evidence of nonlocal hydrodynamic influence on the dynamic contact angle 显示文摘 | Blake T D Bracke M Shikhmurzaev Y D | 1999 | Phys Fluids1999，11，8： | 1 |
| 17 | Effect of Protein Composition and Homogenisation on the Stability of Acidified Milk Drinks 显示文摘 | SEDMEMEYER F BRACK M RADEMACHER B | 2004 | International Dairy Journal2004，14，4： | 1 |
| 18 | Safty and cost effectiveness of a 10 X 109/L trigger forprophylactic platelet transfusions compared with the traditional20 X 109 /L trigger: a prospective comparative trial in 105 pa-tients with acute myeloid leukemia 显示文摘 | Wandt H Frank M Ehninger G* Schneider C Brack N DaoudA | 1998 | Blood1998，91，： | 1 |
| 19 | Tracheal lobular capillary hemangioma:a rare cause of recurrent hemoptysis显示文摘 | Irani S Brack T Pfaltz M | 2003 | Chest2003，123，6： | 1 |
| 20 | Effect of protein composition and homogenisation on the stability of acidified milk drinks显示文摘 | Sedlmeyer F Brack M Rademacher B | 2004 | International Dairy Journal2004，14，4： | 1 |
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