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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘 | Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q | 2010 | EN2010，，5： | 2 |
| 3 | Information Acquisition in desert ant navigation显示文摘 | Gao J Wang L Bo M | 2006 | International Joumal of Information Acquisi-tion2006，3，01： | 1 |
| 4 | Dose-dependent effect of anti-CTLA-4 on survival in sepsis显示文摘 | Inoue S Bo L Bian J | | 0，，01： | 1 |
| 5 | Risk factors for early postoperative cognitive dysfunction after non-coronary bypass surgery in Chinese population 显示文摘 | Xu T Bo L Wang J | 2013 | J Cardiothorac Surg2013，8，： | 1 |
| 6 | Dose-dependent effect of anti- CTLA-4 on survival in sepsis 显示文摘 | Inoue S Bo L Bian J | 2011 | Shock2011，36，1： | 1 |
| 7 | Structure and digestibility of endosperm water-soluble a-glucans from different sugary maize mutants 显示文摘 | MING M RONG L BO J | 2014 | Food Chemistry2014，143，143： | 1 |
| 8 | Genetic interactions among floral homeotic genes of Arabidopsis显示文摘 | BO WEMAN J L | 1991 | Development1991，112，： | 1 |
| 9 | Black carbon affects the cycling of non-blackcarbon in soil显示文摘 | Liang BQ Lehmann J Sohi SP Thies JE Neill BO Trujillo L Gaunt J Solomon D Groossman J Neves EG Luizao FJ | 2010 | Organic Geochemistry2010，41，2： | 1 |
| 10 | Expression of oxidored nitro domain- containing protein 1 ( NOR1 ) impairs nasopharyngeal carcinoma cells adaptation to hypoxia and inhibits PDK1 expression 显示文摘 | Bo X Mei Y Wen J L | 2014 | Mol Cell Biochem2014，393，2： | 1 |
| 11 | Commuter route optimized energy management of hybrid electric vehi- cles显示文摘 | Viktor L Lars J M Bo E | 2014 | IEEE Transactions on Intelligent Transporta- tion Systems2014，15，3： | 1 |
| 12 | Dose - dependent effect of anti - C/LA -4 on survival in sepsis显示文摘 | Inoue S Bo L Bian J | 2011 | Shock2011，36，1： | 1 |
| 13 | On the first passage times of reflected O-U processes with two-sided barriers显示文摘 | Bo L J Zhang L D Wang Y J | 2006 | Queueing Systems2006，54，4： | 1 |
| 14 | Markov-modulated jump: diffusions for currency option pricing显示文摘 | Bo L J Wang Y J 'fang X W | 2010 | Insurance: Mathematics and Economics2010，46，3： | 1 |
| 15 | Information acquisition in deserr ant navigation显示文摘 | Gao J Wang L Bo M | 2006 | International Journal of Information Acquisition2006，3，1： | 1 |
| 16 | Optimum design and analysis based on independent reaction amount for distillation column with side reactors: production of benzyl chloride 显示文摘 | Ding L H Tang J H Cui M F Bo C M Chen X Qiao X | 2011 | Industrial & Engineering Chemistry Research2011，50，11： | 1 |
| 17 | Sequence analysis and regulation of a cuticle degrading serine protease from the nematophagous fungus Arthrobotrys oligospora 显示文摘 | A hman J Bo EK Rask L | 1996 | Microbtology1996，142，： | 1 |
| 18 | Blood-retinal barrier 显示文摘 | Cunha-Vaz J Bernardes R l~bo C | 2011 | Eur J Ophthalmol2011，21，6： | 1 |
| 19 | Facile Green Synthesis of Nitrogen-doped Porous Carbon and Its Use for Electrocatalysis Towards Nitrobenzene and Hydrazine显示文摘 | YAN L J BO X J ZHANG Y F | 2014 | Electrochim Acta2014，137，10： | 1 |
| 20 | Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8virus infection:a descriptive study显示文摘 | Chen H Yuan H Gao R Zhang J Wang D Xiong Y Fan G Yang F Li X Zhou J Zou S Yang L Chen T Dong L Bo H Zhao X Zhang Y Lan Y Bai T Dong J Li Q Wang S Zhang Y Li H Gong T Shi Y Ni X Li J Zhou J Fan J Wu J Zhou X Hu M Wan J Yang W Li D Wu G Feng Z Gao GF Wang Y Jin Q Liu M Shu Y | 2014 | Lancet2014，383，： | 1 |
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