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| 1 | Interstitial cells of Cajal in the gut-A gastroenterologist’s point of view显示文摘Alterations of normal function of interstitial cells of Cajal (ICC) are reported in many intestinal disorders. Diagnosis of their involvement is rare (infrequent), but necessary to propose a specifi c treatment. This article reviews the place of ICC in the pathogenesis of achalasia, gastroesophageal reflux disease, infantile hypertrophic pyloric stenosis, chronic intestinal pseudoobstruction and slow transit constipation. Moreover we discuss the role of the Cajal cells in the development of stromal tumors of the gastrointestinal tract. | Lucian M Negreanu Philippe Assor Bogdan Mateescu Catalin Cirstoiu | 2008 | World Journal of Gastroenterology2008，14，41： | 27 |
| 2 | Lipid peroxidation and antioxidant status in colorectal cancer显示文摘AIM: Reactive oxygen species (ROS) can induce carcinogenesis via DNA injury. Both enzymatic and non-enzymatic parameters participate in cell protection against harmful influence of oxidative stress. The aim of the present study was to assess the levels of final lipid peroxidation products like malondialdehyde (MDA) and 4-hydroxy-2-nonenal (4-HNE) in primary colorectal cancer. Moreover, we analysed the activity of main antioxidative enzymes, superoxide dismutase (Cu, Zn-SOD),catalase (CAT), glutathione peroxidase (GSH-Px) and glutathione reductase (GSSRG-R) and the level of nonenzymatic antioxidants (glutathione, vitamins C and E).METHODS: Investigations were conducted in 81 primary colorectal cancers. As a control, the same amount of sample was collected from macroscopically unchanged colon regions of the most distant location to the cancer.Homogenisation of specimens provided 10% homogenates for our evaluations. Activity of antioxidant enzymes and level of glutathione were determined by spectrophotometry.HPLC revealed levels of vitamins C and E and served as a method to detect terminal products of lipid peroxidation in colorectal cancer.RESULTS: Our studies demonstrated a statistically significant increase in the level of lipid peroxidation products (MDA-Adc.muc.-2.65±0.48 nmol/g, Adc. G3-2.15±0.44 nmol/g, clinical Ⅳ stage 4.04±0.47 nmol/g, P<0.001 and 4-HNE-Adc.muc.-0.44±0.07 nmol/g, Adc. G3-0.44±0.10 nmol/g, clinical Ⅳstage 0.52±0.11 nmol/g, P<0.001) as well as increase of Cu,Zn-SOD (Adc.muc.-363±72 U/g, Adc. G3-318±48 U/g,clinical Ⅳ stage 421±58 U/g, P<0.001), GSH-Px (Adc.muc.-2143±623 U/g, Adc. G3-2005±591 U/g, clinical Ⅳ stage 2467±368 U/g, P<0.001) and GSSG-R (Adc. muc.-880±194 U/g,Adc. G3-795±228 U/g, dinical Ⅳ stage 951±243 U/g, P<0.001)in primary tumour comparison with normal colon (MDA1.39±0.15 nmol/g, HNE-0.29±0.03 nmol/g, Cu, Zn-SOD-117±25 U/g, GSH-Px-1723±189 U/g, GSSG-R-625±112 U/g)especially in mucinous and G3-grade adenocarcinomas as well as clinical Ⅳ stage of colorectal cancer. We also observed a decrease of CAT activity (Adc.muc. -40±14 U/g,clinical Ⅳ stage 33±18 U/g vs84±17 U/g, P<0.001) as well as a decreased level of reduced glutathione (clinical Ⅳ stage 150±48 nmol/g vs 167±15 nmol/g, P<0.05) and vitamins C and E (vit. C-clinical Ⅳ stage 325±92 nmol/g vs 513±64 nmol/g, P<0.001; vit. E-clinical Ⅳ stage 13.3±10.3nmol/g vs37.5±5.2 nmol/g).CONCLUSION: Colorectal carcinogenesis is associated with serious oxidative stress and confirms that gradual advancement of oxidative-antioxidative disorders is followed by progression of colorectal cancer. | Elzbieta Skrzydlewska Stanislaw Sulkowski Mariusz Koda Bogdan Zalewski Luiza Kanczuga-Koda Mariola Sulkowska | 2005 | World Journal of Gastroenterology2005，11，3： | 12 |
| 3 | A Comparative Analysis of Binary Logistic Regression and Analytical Hierarchy Process for Landslide Susceptibility Assessment in the Dobrovǎt River Basin,Romania显示文摘A correct assessment of the landslide susceptibility component is extremely useful for the diminution of associated potential risks to local economic development, particularly in regard to land use planning and soil conservation. The purpose of the present study was to compare the usefulness of two methods, i.e., binary logistic regression(BLR) and analytical hierarchy process(AHP), for the assessment of landslide susceptibility over a 130-km^2 area in the Moldavian Plateau(eastern Romania) region, where landslides affect large areas and render them unsuitable for agriculture. A large scale inventory mapping of all types of landslides(covering 13.7% of the total area) was performed using orthophoto images, topographical maps, and field surveys. A geographic information system database was created, comprising the nine potential factors considered as most relevant for the landsliding process. Five factors(altitude, slope angle, slope aspect, surface lithology, and land use) were further selected for analysis through the application of a tolerance test and the stepwise filtering procedure of BLR. For each predictor, a corresponding raster layer was built and a dense grid of equally spaced points was generated, with an approximately equal number of points inside and outside the landslide area, in order to extract the values of the predictors from raster layers. Approximately half of the total number of points was used for model computation, while the other half was used for validation. Analytical hierarchy process was employed to derive factor weights, with several pair-wise comparison matrices being tested for this purpose. The class weights, on a scale of 0 to 1, were taken as normalized landslide densities. A comparison of results achieved through these two approaches showed that BLR was better suited for mapping landslide susceptibility, with 82.8% of the landslide area falling into the high and very high susceptibility classes. The susceptibility class separation using standard deviation was superior to either the equal interval or the natural break method. Results from the study area suggest that the statistical model achieved by BLR could be successfully extrapolated to the entire area of the Moldavian Plateau. | Cristian V.PATRICHE Radu PIRNAU Adrian GROZAVU Bogdan ROSCA | 2016 | Pedosphere2016，26，3： | 11 |
| 4 | 支架自显影定位法体外开窗技术在主动脉弓部腔内修复术中的应用:附113例国际多中心病例回顾性分析显示文摘背景与目的:胸主动脉腔内修复术(TEVAR)已成为治疗降主动脉疾病的一线治疗方式。在治疗累及主动脉弓部疾病时,体外开窗(PMF)是目前常用于重建弓部分支动脉的技术之一。它是指在选择合适的主动脉覆膜支架后,根据弓上分支动脉的位置,在覆膜支架相应位置上除去覆膜,建立人造的“窗孔”,在将有窗孔的大动脉支架准确对位释放后再释放分支支架。本文介绍一种利用主动脉支架本身所携带的不透X线标志快速、准确地将窗孔与分支动脉开口对准的开窗方法—支架自显影定位PMF技术(S-F技术),并通过总结利用该方法进行TEVAR的一组患者临床资料和手术以及随访数据,探讨利用S-F技术在主动脉弓部疾病腔内治疗中的技术特点和其应用价值。方法:回顾性分析2015年12月—2020年6月利用S-F技术行TEVAR治疗的中国湖南中南大学湘雅二医院血管外科和其他7个国家的国家级血管外科中心共113例主动脉弓部疾病患者的基本数据、术中技术数据和术后随访数据。结果:患者均根据S-F技术的操作标准流程进行的TEVAR,即时手术成功率为100%,共植入胸主动脉覆膜支架118枚,其中植入桥接支架35例。手术时间(62.9±17.4)min,X线操作时间(23.1±9.8)min,造影剂用量(81.2±22.5)mL。术中开窗对位准确率为98.2%。补救性植入烟囱支架1例(0.9%),矫正后对位回准1例(0.9%)。开窗同时保留弓上三分支动脉2例(1.8%),开窗同时保留左颈总动脉(LCCA)和左锁骨下动脉(LSA)6例(5.3%),保留LSA 110例(97.3%)。术后1个月内无死亡病例,无严重并发症发生。术后1周复查发现Ⅰ型内漏7例(6.2%)。随访时间中位时间24.5个月,死亡2例(1.8%);术后分支动脉闭塞3例(2.7%),分别发生在术后3个月(2例)和术后6个月(1例)。结论:S-F技术为治疗累及主动脉弓部疾病重建弓上分支动脉提供了一种可供选择的方法,是全腔内重建主动脉弓部方法技术上的一项进步。 | 舒畅 李鑫 李全明 何昊 黎明 王暾 杨晨紫 王沫 周海洋 JoséFernando Teixeira Suko Adiarto Tao Fan Bogdan Cherpark Imaev Timur Makhkamov Najmiddin Pavel Charnahlaz Giorgi Kheladze | 2020 | 中国普通外科杂志2020，29，12： | 10 |
| 5 | Axon degeneration: make the Schwann cell great again显示文摘Axonal degeneration is a pivotal feature of many neurodegenerative conditions and substantially accounts for neurological morbidity. A widely used experimental model to study the mechanisms of axonal degeneration is Wallerian degeneration(WD), which occurs after acute axonal injury. In the peripheral nervous system(PNS), WD is characterized by swift dismantling and clearance of injured axons with their myelin sheaths. This is a prerequisite for successful axonal regeneration. In the central nervous system(CNS), WD is much slower, which significantly contributes to failed axonal regeneration. Although it is well-documented that Schwann cells(SCs) have a critical role in the regenerative potential of the PNS, to date we have only scarce knowledge as to how SCs ‘sense' axonal injury and immediately respond to it. In this regard, it remains unknown as to whether SCs play the role of a passive bystander or an active director during the execution of the highly orchestrated disintegration program of axons. Older reports, together with more recent studies, suggest that SCs mount dynamic injury responses minutes after axonal injury, long before axonal breakdown occurs. The swift SC response to axonal injury could play either a pro-degenerative role, or alternatively a supportive role, to the integrity of distressed axons that have not yet committed to degenerate. Indeed, supporting the latter concept, recent findings in a chronic PNS neurodegeneration model indicate that deactivation of a key molecule promoting SC injury responses exacerbates axonal loss. If this holds true in a broader spectrum of conditions, it may provide the grounds for the development of new glia-centric therapeutic approaches to counteract axonal loss. | Keit Men Wong Elisabetta Babetto Bogdan Beirowski | 2017 | Neural Regeneration Research2017，12，4： | 10 |
| 6 | Noninvasive assessment of portal hypertension in cirrhosis:Liver stiffness and beyond显示文摘Liver stiffness measurement(LSM)is a good,but still limited tool to noninvasively assess complications and prognosis in patients with advanced liver disease.This review aims to consider the role of LSM for the diagnosis of portal hypertension-related complications and for assessment of prognosis in cirrhotic patients,and to highlight the drawbacks as well as some alternatives for improving the performance.Hence,this field is far from being closed,and deserves more attention.There is still a place for more carefully designed studies to find new,innovative and reliable approaches. | Horia Stefanescu Bogdan Procopet | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 7 | 迷走神经与肺部疾病(英文)显示文摘迷走神经支配人体的内脏器官,其传出纤维激活后可释放乙酰胆碱调节器官功能,而传入纤维能感知器官中机械和化学信号,并将其传入中枢,这种双向交流使得神经中枢能够反馈性调节器官功能。在呼吸系统中,迷走神经调节气道张力、血流供应、黏液分泌及呼吸型式。近来发现,迷走神经与免疫系统产生交互作用,在肺部疾病的发病机制中发挥重要作用,如哮喘、慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)、急性呼吸窘迫综合征(acute respirtory distress sydrome,ARDS)、肺纤维化和肺癌。在疾病状态下,多种细胞释放的细胞因子、化学因子和其他介质激活迷走神经,将免疫信息传到中枢,从而改变病程。激活迷走神经还可以释放神经肽调节免疫细胞的活动,并通过胆碱能抗炎通路控制肺部炎症,因此了解迷走神经在神经免疫反应中的作用对于肺部疾病的临床治疗有着重要意义。 | 宋娜娜 刘俊 Bogdan Moldoveanu Juan Guardiola Rafael Perez 於峻 | 2012 | 复旦学报(医学版)2012，39，2： | 8 |
| 8 | Levels of v5 and v6 CD44 splice variants in serum of patients with colorectal cancer are not correlated with pT stage,histopathological grade of malignancy and clinical features显示文摘AIM:This study was designed to compare the levels of v5 and v6 splice variants of CD44 evaluated using ELISA test in the serum of patients with colorectal cancer in different stages of progression of the disease estimated in pT stage according to WHO score, histopathological grade of malignancy and some clinicopathological features.METHODS:The serum obtained from 114 persons with colorectal adenocarcinomas was examined using ELISA method, pT stage and grade of malignancy of the tumour were examined in formalin fixed and paraffin embedded materials obtained during operation.RESULTS:Only the level of CD44 v5 in the serum of patients before operation with G2 pT4 tumour was lower than that in other probes and the difference was statistically significant.We did not find any other correlations between the level of v5 and v6 CD44 variants and other evaluated parameters.CONCLUSION:The level of CD44 v5 and v6 estimated by ELISA test in the serum can not be used as a prognostic factor in colorectal cancer. | Bogdan Zalewski | 2004 | World Journal of Gastroenterology2004，10，4： | 8 |
| 9 | 空气耦合超声换能器的频域声场研究显示文摘考虑介质的衰减及其引起的频散对频域声场的影响,提出幂函数衰减介质中圆形换能器声场的解析公式。基于该公式研究空气耦合超声换能器的轴向声压与径向声压分布特征。结果表明:空气中的衰减是引起声场变化的主要因素;相对于零衰减介质,空气中的声压幅度随着传播距离的增加而明显降低,近场长度明显减小,近场内轴向声压的零点、极大值点无偏移,径向声压分布和声束扩散角无变化。研究结果对于空气耦合换能器的设计、空气耦合声场的测量、校准具有重要参考价值,并可以作为ASTM E1065/E1065-14和IEC 62127标准的补充。 | 李骥 李力 邓勇刚 PIWAKOWSKI Bogdan 陈法法 | 2019 | 机械工程学报2019，55，10： | 7 |
| 10 | Growth performance,gastrointestinal weight,microbial metabolites and apparent retention of components in broiler chickens fed up to 11%rice bran in a corn-soybean meal diet without or with a multi-enzyme supplement显示文摘We investigated the effects of adding up to 11% rice bran(RB) in corn-soybean meal diets fed to broiler chickens without or with a multi-enzyme supplement(MES). The MES supplied xylanase, b-glucanase invertase, protease, cellulase, a-amylase and mannanase with targeted activity of 2,500, 300, 700, 10,0001,200, 24,000, and 20 U/kg of feed, respectively. The study used a two-phase feeding program(starter d 0 to 24; finisher, d 25 to 35) with RB added at 5% and 11%, respectively creating 4 diets in each phase Diets were iso-caloric and iso-nitrogenous and contained phytase(500 FTU/kg) and TiO_2 as a digestibility marker. Three hundred and sixty d-old male Ross 708 broiler chicks were placed in cages based on BW(15 birds/cage) and allocated to 4 diets(n = 6). Birds had free access to feed and water. Body weight and feed intake were recorded. Excreta samples were collected 3 d prior to the end of each phase for apparent retention(AR) of components. Samples of birds were sacrificed on d 24 and 35 for gut weight and ceca digesta for organic acid content. There was no interaction(P > 0.10) between RB and MES on BWG and FCR in starter or finisher phase. In finisher phase, birds fed MES had better BWG(961 versus 858 g) and FCR(1.69 versus 1.86) than birds fed non-MES diets(P < 0.01). Feeding RB reduced(P = 0.02) BWG in finisher phase resulting in lower d 35 BW. Birds fed RB had higher(P 0.01) gizzard weight on d 24 and 35 than non-RB birds. An interaction(P 0.01) between RB and MES on concentrations of propionic and iso-butyric acids in ceca digesta showed that MES reduced these acids in non-RB diet. The AR of gross energy was higher(P < 0.02) for MES versus non-MES birds in starter and finisher phases. In conclusion independently, RB increased gizzard weight and reduced final BW whereas MES improved growth and energy utilization. | Juan Sanchez Aizwarya Thanabalan Tanka Khanal Rob Patterson Bogdan A.Slominski Elijah Kiarie | 2019 | Animal Nutrition2019，，1： | 6 |
| 11 | Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology显示文摘Virtually all drug interventions that have been successful pre-clinically in experimental stroke have failed to prove their efficacy in a clinical setting. This could be partly explained by the complexity and heterogeneity of human diseases as well as the associated co-morbidities which may render neuroprotective drugs less efficacious in clinical practice. One aspect of crucial importance in the physiopathology of stroke which is not completely understood is neuroinflammation. At the present time, it is becoming evident that subtle, but continuous neuroinflammation can provide the ground for disorders such as cerebral small vessel disease. Moreover, advanced aging and a number of highly prevalent risk factors such as obesity, hypertension, diabetes and atherosclerosis could act as 'silent contributors' promoting a chronic proinflammatory state. This could aggravate the outcome of various pathological entities and can contribute to a number of subsequent post-stroke complications such as dementia, depression and neurodegeneration creating a pathological vicious cycle. Moreover, recent data suggests that the inflammatory process might be closely linked with multiple neurodegenerative pathways related to depression. In addition, pro-inflammatory cytokines could play a central role in the pathophysiology of both depression and dementia. | Raluca Elena Sandu Ana Maria Buga Adriana Uzoni Eugen Bogdan Petcu Aurel Popa-Wagner | 2015 | Neural Regeneration Research2015，10，9： | 6 |
| 12 | Effect of interferon alpha and ribavirin treatment on serum levels of transforming growth factor-β1,vascular endothelial growth factor,and basic fibroblast growth factor in patients with chronic hepatitis C显示文摘AIM:To assess the role of transforming growth factor-β1(TGF-β1),vascular endothelial growth factor(VEGF)andbasic fibroblast growth factor(bFGF)in the pathogenesisof fibrosis associated with chronic hepatitis C(CHC)and to evaluate the influence of the antiviral therapyon above parameter levels depending on the treatmentresults(complete response or no response).METHODS:Study group included 100 patients withCHC,in whom fibrosis in liver specimens was assessed(Scheuer fibrosis score:1-4 points).Control groupincluded 30 subjects with antibodies anti-HCV presentand persistently normal ALT level,without fibrosis(Scheuer fibrosis score:0 points).Concentration ofstudied parameters was assayed in the serum byimmunoenzymatic method before and after the therapywith interferon alpha-2b and ribavirin.RESULTS:TGF-β1 levels were significantly higher in thestudy group compared to the control group(35.89 vs 32.37ng/mL;P=0.023).Such differences were not found in VEGFand bFGF levels.In patients showing complete response(negative HCV RNA and normal ALT level),significantincrease in VEGF(112.8 vs 315.03 pg/mL;P<0.05)andbFGF(2.51 vs 15.79 pg/mL;P=0.04)levels were found.Significant decrease in TGF-β1 level was observed bothin responders(37.44 vs 30.02 ng/mL;P=0.05),andin non-responders(38.22 vs 30.43 ng/mL;P=0.043).bFGF levels before the treatment were significantly lower(2.51 vs 5.94 pg/mL;P=0.04),and after the treatmentsignificantly higher(15.79 vs 4.35 pg/mL;P=0.01) in patients with complete response than in those with noresponse.CONCLUSION:Among the analyzed parametersTGF-β1 seems to play the most important role in thepathogenesis of fibrosis in CHC.Levels of this factor aresignificantly lower in subjects who do not have fibrosisdeveloped in them.Good therapeutic effect in CHCpatients is associated with significant changes in TGF-β1,VEGF,and bFGF levels,bFGF seems to have the highestusefulness in the prognosis of treatment efficacy. | Ewa Janczewska-Kazek Bogdan Marek Dariusz Kajdaniuk Halina BorgieI-Marek | 2006 | World Journal of Gastroenterology2006，12，6： | 5 |
| 13 | Diagnostic challenges in non-cirrhotic portal hypertension-porto sinusoidal vascular disease显示文摘Non-cirrhotic portal hypertension consists of a group of diseases characterized by signs and complications of portal hypertension,which differ from cirrhosis through histological alterations,hemodynamic characterization and,clinical outcome.Because of the similarities in clinical presentation and imaging signs,frequently these patients,and particularly those with porto-sinusoidal vascular disease(PSVD),are misdiagnosed as having liver cirrhosis and thus raising difficulties in their diagnosis.The most challenging differentiation to be considered is between PSVD and cirrhosis and,although not pathognomonic,liver biopsy is still the standard of diagnosis.Although they still require extended validation before being broadly used,new non-invasive methods for the diagnosis of porto-sinusoidal vascular disease,like transient elastography,contrast-enhanced ultrasound or metabolomic profiling,have shown promising results.Another issue is the differentiation between PSVD and chronic extrahepatic portal vein obstruction,especially now when it is known that 40%of patients suffering from PSVD develop portal vein thrombosis.In this particular case,once the portal vein thrombosis occurred,the diagnosis of PSVD is impossible according to the current guidelines.Moreover,so far,the differentiation between PSVD and sinusoidal obstruction syndrome has not been clear so far in particular circumstances.In this review we highlighted the diagnostic challenges regarding the PSVD,as well as the current techniques used in the evaluation of these patients. | Oana Nicoara-Farcau Ioana Rusu Horia Stefanescu Marcel Tanțau Radu Ion Badea Bogdan Procopet | 2020 | World Journal of Gastroenterology2020，26，22： | 4 |
| 14 | Cancer stem cells: Involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics显示文摘Pancreatic cancer is one of the most aggressive and lethal malignancies. Despite remarkable progress in understanding pancreatic carcinogenesis at the molecular level, as well as progress in new therapeutic approaches, pancreatic cancer remains a disease with a dismal prognosis. Among the mechanisms responsible for drug resistance, the most relevant are changes in individual genes or signaling pathways and the presence of highly resistant cancer stem cells(CSCs). In pancreatic cancer, CSCs represent 0.2%-0.8% of pancreatic cancer cells and are considered to be responsible for tumor growth, invasion, metastasis and recurrence. CSCs have been extensively studied as of late to identify specific surface markers to ensure reliable sorting and for signaling pathways identified to play a pivotal role in CSC self-renewal. Involvement of CSCs in pancreatic cancer pathogenesis has also highlighted these cells as the preferential targets for therapy. The present review is an update of the results in two main fields of research in pancreatic cancer, pathogenesis and therapy, focused on the narrow perspective of CSCs. | Cristiana Pistol Tanase Ana Iulia Neagu Laura Georgiana Necula Cristina Mambet Ana-Maria Enciu Bogdan Calenic Maria Linda Cruceru Radu Albulescu | 2014 | World Journal of Gastroenterology2014，20，31： | 4 |
| 15 | 细胞学方法治疗缺血性心脏病的新进展显示文摘尽管缺血性心脏病在防治手段,介入治疗方面有了很大的进展,但是缺血性心脏病仍然是世界上导致患者死亡最多的疾病之一.为了使缺血性心脏病患者心肌梗死部位心肌再生,研究人员尝试了多种物理治疗方法[1-3],如移植乳内动脉到坏死部位的心肌组织[4],或是应用药物治疗,如肝素[2],血管内皮生长因子(VEGF),肝素结合生长因子1和碱性成纤维细胞生长因子[7-10]. | Yifu Zhou Suna Wang Bogdan Kindzelski Keith A Horvath 程斌 黄益民 | 2014 | 心肺血管病杂志2014，33，6： | 4 |
| 16 | Mg-Al/PTEE烟火药爆炸性能的研究(英)显示文摘The object of the research are explosive properties of the pyrotechnic composite consist of fine grade magnesium-aluminium powder(PAM)and highly dispersed polytetrafluorethylene(PTFE).The composite reveals high resistance to all mechanical and thermal impulses and is extremely sensitive to hot sparks and open fire.The burning rate of the composition changes from 1 cm·s-1 to 100 m·s-1 along with decreasing its density.Charges of the composition with density below 1 g·cm-3 burn so violently,that the phenomena is similar to explosion.Charges with density above 1.1 g·cm-3 burn relatively rapidly and stably.The main part of the paper concerns the pressure impulses in the air generated during high-rate burning of the composition of bulk density.The nature of the generated pressure impulse is not that of a typical shock wave.A rise of pressure over the distance from the point of explosion to the maximum value lasts 50-100 milliseconds,while for shock waves this factor is less than a microsecond for equivalent charges.The methods of initiation of the composition influence the shape and parameters of the pressure impulse.The explanation of the nature of great changes of the composition burning rate has been proposed.The effect described in the paper was used for evaluation of explosive pressure resistance of industrial doors and windows. | Bogdan ZYGMUNT | 2007 | 含能材料2007，15，6： | 4 |
| 17 | 欧盟可再生能源市场和生物燃料的发展显示文摘文章旨在介绍可再生能源市场的发展,并特别关注欧盟的生物燃料。该分析包括可再生能源在岛屿总能源消费中所占份额,2004年~2016年可再生能源的变化和液体生物燃料数量的数据。笔者用描述性和统计方法来描述生物能源的变化欧洲联盟(EU)中生物能源发展的变化。生物燃料和可再生废物的最大份额出现在拉脱维亚(31.2%)、芬兰(26.7%)和瑞典(24.8%)。2015年风能比例最高的国家是丹麦(7.2%)、葡萄牙(4.3%)、爱尔兰(4.0%)和西班牙(3.5%)。2015年太阳能的最高份额出现在塞浦路斯(3.5%)、西班牙(2.6%)和希腊(2.2%)。2015年,地热能贡献最大的国家是意大利(3.5%)、葡萄牙(0.8%)和斯洛文尼亚(0.7%)。2015年,水力发电量最大的国家是瑞典(14.2%),奥地利(9.6%)和斯洛文尼亚(5.0%)。在2004年至2017年间,马耳他(140.3%)、塞浦路斯(101.1%)和英国(71.9%)的可再生能源电力份额变化系数最高。此外,2004-2017年间,可再生能源中供暖和制冷所占份额变动系数最高的是马耳他(72.4%)、英国(69.81%)和匈牙利(44.91%)。此外,2004~2017年在芬兰(113.78%),马耳他(115.52%)和比利时(96.53%)可再生能源中交通运输份额的变化系数最高。欧盟最大的乙醇和生物柴油生产商是德国、法国和波兰。聚类分析数据表明,德国和法国在生物柴油和乙醇生产中至关重要。在2003年至2017年间,生物柴油的产量从719.32亿升增加到133.23亿升(增长1852.2%)。然而,在2014年至2017年间,生物燃料生产停滞,从136.73亿升下降到133.23亿升(-2.56%)。到2030年,市场情况和对绿色能源需求的增加会引起乙醇和植物油酯的产量增加,这将为该部门的发展做出贡献。 | Piotr Borawski Aneta Beldycka-Borawska Elzbieta Jadwiga Szymanska Krzysztof Jozef Jankowski Bogdan Dubis James W Dunn 王健(译) | 2019 | 中国沼气2019，37，6： | 3 |
| 18 | Viscoelastic tests in liver disease: where do we stand now?显示文摘Hemostasis is a complex physiological process based on the balance between procoagulant and anticoagulant systems to avoid pathological bleeding or thrombosis.The changes in standard coagulation tests in liver disease were assumed to reflect an acquired bleeding disorder,and cirrhotic patients were considered naturally anticoagulated.In the light of the new evidence,the theory of rebalanced hemostasis replaced the old concept.According to this model,the hemostatic alteration leads to a unique balance between pro-coagulant,anticoagulant,and fibrinolytic systems.But the balance is fragile and may prone to bleeding or thrombosis depending on various risk factors.The standard coagulation tests[INR(international normalized ratio),platelet count and fibrinogen]only explore parts of the hemostasis,not offering an entire image of the process.Rotational thromboelastometry(ROTEM)and thromboelastography(TEG)are both point of care viscoelastic tests(VET)that provide real-time and dynamic information about the entire hemostasis process,including clot initiation(thrombin generation),clot kinetics,clot strength,and clot stability(lysis).Despite prolonged PT/INR(international normalized ratio of prothrombin time)and low platelet counts,VET is within the normal range in many patients with both acute and chronic liver disease.However,bleeding remains the dominant clinical issue in patients with liver diseases,especially when invasive interventions are required.VET has been shown to asses more appropriately the risk of bleeding than conventional laboratory tests,leading to decrial use of blood products transfusion.Inappropriate clotting is common but often subtle and may be challenging to predict even with the help of VET.Although VET has shown its benefit,more studies are needed to establish cut-off values for TEG and ROTEM in these populations and standardization of transfusion guidelines before invasive interventions in cirrhotic patients/orthotopic liver transplantation. | Alina Buliarca Adelina Horhat Tudor Mocan Rares Craciun Bogdan Procopet Zeno Sparchez | 2021 | World Journal of Gastroenterology2021，27，23： | 3 |
| 19 | Sol-gel synthesis, surface and magnetic properties of nanocrystalline SmAlO_3显示文摘Nanocrystals of single-phase samarium monoaluminate (SmAlO3) were synthesized and studied for the first time. Malic acid was employed as a new complexing agent in the sol-gel process. The material was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDS), specific surface area and density. The lowest size of the nanoparticles was about 50–60 nm and some of them formed agglomerates. The binding energies of core-level electrons of Sm (3d, 4d, 4f, 5p, 5s), Al (2s, 2p) and O (1s, 2s) in nanocrystalline SmAlO3 were obtained by X-ray photoelectron spectroscopy (XPS) and found shifted in respect to the correspond- ing values for the same elements. The temperature dependence of the AC magnetic susceptibility of the substance was determined between 2.5 and 250 K. The experimental molar magnetic susceptibility was compared with the theoretical one of Sm3+ ions. The nanomaterial was found paramagnetic in the specified temperature range with Curie-type paramagnetism below 12 K. | Dimitar Petrov Bogdan Angelov Vasil Lovchinov | 2010 | Journal of Rare Earths2010，28，4： | 3 |
| 20 | Dietary habits, lifestyle factors and neurodegenerative diseases显示文摘Worldwide stroke is increasing in parallel with modernization,changes in lifestyle,and the growing elderly population.Our review is focused on the link between diet,as part of‘modern lifestyle’,and health in the context of genetic predisposition of individuals to‘unhealthy’metabolic pathway activity.It is concluded that lifestyle including high sugar diets,alcohol and tobacco addiction or high fat diets as well as ageing,brain injury,oxidative stress and neuroinflammation,negatively influence the onset,severity and duration of neurodegenerative diseases.Fortunately,there are several healthy dietary components such as polyunsaturated fatty acids and the anti-oxidants curcumin,resveratrol,blueberry polyphenols,sulphoraphane,salvionic acid as well as caloric restriction and physical activity,which may counteract ageing and associated neurodegenerative diseases via increased autophagy or increased neurogenesis in the adult brain. | Aurel Popa-Wagner Dinu Iuliu Dumitrascu Bogdan Capitanescu Eugen Bogdan Petcu Roxana Surugiu Wen-Hui Fang Danut-Adrian Dumbrava | 2020 | Neural Regeneration Research2020，15，3： | 3 |
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