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| 1 | 北京夏季高温高湿和降水过程对大气颗粒物谱分布的影响显示文摘2004—07—13~2004—08—23使用TDMPS-APS系统在线测量颗粒物的数浓度谱分布,并于07—16~07—18选取了高温闷热夜晚、日间高温高湿和雨后晴朗干洁3种天气条件,使用多级串联撞击式采样器(MOUDI)测量颗粒物的质量浓度谱分布,结果表明,高温高湿天气条件下颗粒物的污染、尤其细粒子污染严重,导致很低的能见度(2.5km);PM1.8和PM10的质量浓度分别为170.68μg/m^3和249.35μg/m^3,细粒子质量浓度占PM10的68%;粒径为50~100nm颗粒物的数浓度最高,为2×10^4~3×10^4个/cm^3;降雨过程对粗粒子和细粒子均有去除作用,对细粒子的去除作用尤为明显;降雨后PM10和PM1.8浓度分别比降雨前降低3倍和6倍;降雨过后的晴朗干洁天气有利于新粒子(3~20nm)的生成,生成的新粒子快速长大到50~100nm;随着污染物的累积,以后几天内又变为污染天气. | 胡敏 刘尚 吴志军 张静 赵云良 Birgit Wehner Alfred Wiedensohler | 2006 | 环境科学2006，27，11： | 117 |
| 2 | Development of early gastric cancer 4 and 5 years after complete remission of Helicobacter pyloriassociated gastric low-grade marginal zone B-cell lymphoma of MALT type显示文摘AIM To report 3 of 120 patients on the German MALT lymphoma trial with H. pYlori-associated gastric MALT Iymphoma who developed early gastric cancer 4 and 5 years, after complete Iymphoma remission following cure of H. pylori infection.PATIENTS AND RESULTS Three patients (two men, 74 and 70 years; one women, 77 years)with H. pylori -associated low-grade MALTlymphoma achieved complete lymphoma remission after being cured. Surveillance endoscopies were performed twice a year in accordance to the protocol. Four years aftercomplete lymphoma remission in two patients,and after 5 years in the other, early gastric adenocarcinoma of the mucosa-type, type Ⅱ a and type Ⅱ c, respectively, was detetcted,which were completely removed by endoscopic mucosa resection. in one patient, the gastric cancer was diagnosed at the same location as the previous. MALT lymphoma, in the other patients it was detected at different sites of the stomach distant from location of the previous MALT lymphoma. The patients were H. pylori negative during the whole follow-up time.CONCLUSION These findings strengthen the importance of regular long-term follow-up endoscopies in patients with complete remission of gastric MALT lymphoma after cure of H.pylori infection. Furthermore, gastric adenocarcinoma may develop despite eradication of H. pylori. | Andrea Morgner Stephan Miehlke Manfred Stolte Andreas Neubauer Birgit Alpen Christian Thiede Hermann Klann Franz-Xaver Hierlmeier Christian Ell Gerhard Ehninger Ekkehard Bayerdorffer | 2001 | World Journal of Gastroenterology2001，7，2： | 28 |
| 3 | 新疆塔里木河下游胡杨树高生长量及其空间分布研究显示文摘以塔里木河下游4个典型断面作为野外调查靶区,根据3a来对塔里木河下游胡杨恢复状况的实地监测数据,分析了影响胡杨树高生长量的因素,并得出中龄段胡杨树高生长量和地下水埋深的回归模型:y=-0.1286x+1.0097。结果显示:在塔里木河下游影响胡杨生长的主要因子是地下水,由回归模型可以得出:当地下水埋深〈4.5m时,中龄胡杨树高生长是显著的;地下水埋深在4.5~6.5m时,胡杨树高生长受到抑制;而当地下水埋深〉6.5m时.胡杨树高生长非常缓慢;地下水埋深〉8m时,胡杨树高生长基本停止。此外,聚丛的群生株无论在树高还是在高生长量上都比散生的单生株显现优势。 | 玉米提·哈力克 柴政 罗淑政 Bodo Coenradie Birgit Kleinschmit | 2008 | 干旱区资源与环境2008，22，5： | 20 |
| 4 | 重污染和新粒子生成过程中城市大气颗粒物数谱分布演变过程显示文摘使用双电迁移性颗粒物粒径谱分析仪和空气动力学颗粒物粒径谱分析仪对北京城市大气颗粒物(3nm^10μm)数浓度谱分布进行长期观测.选取2006年春节期间出现的一次重污染事件和一次新粒子生成过程,对期间颗粒物数谱分布特征及演变过程进行分析.在重污染事件中3~10nm颗粒物(平均数浓度46cm?3)几乎在大气中消失,而新粒子生成事件中核模态颗粒物数浓度最高达到3.5×104cm?3.这种现象可以通过颗粒物的碰并汇和低挥发性气态前体物的凝结汇从颗粒物的汇和源两个角度进行解释:重污染事件中,3~10nm颗粒物的碰并汇为1.1×10?2~1.2×10?3s?1,显著高于新粒子生成过程(9.9×10?4~1.4×10?4s?1);在新粒子生成过程中,参与成核的低挥发性气态前体物的凝结汇为0.01s?1,显著低于重污染事件(0.13s?1).研究结果表明在分析极端大气环境中的颗粒物数谱分布时,除交通和气象因素外,碰并和凝结过程的影响也需要给予足够的重视. | 吴志军 胡敏 岳玎利 Birgit WEHNER Alfred WIEDENSOHLEP | 2011 | 中国科学:地球科学2011，41，8： | 17 |
| 5 | Heat Shock Factors HsfB 1 and HsfB2b Are Involved in the Regulation of Pdf1.2 Expression and Pathogen Resistance in Arabidopsis显示文摘以便估计热的功能的角色在 Arabidopsis 的导致压力的班 B 热吃惊因素,我们调查了 AtHsfB1 和 AtHsfB2b 的 T-DNA 猛烈异种。在异种的 defensin 基因 Pdf1.2a/b 的基础 mRNA 水平的一条起来规定种的作为强壮揭示的两倍猛烈 hsfB1/hsfB2b 植物的 Micorarray 分析。Pdf 表示被 jasmonic 酸处理或感染进一步与 necrotrophic 真菌 Alternaria brassicicola 提高。单个变异的 hsfB2b 和双变异的 hsfB1/B2b 显著地在 A 以后在疾病抵抗被改进。brassicicola 感染。为和 Pdf1.2 的倡导者的 Hsf 的一个直接相互作用没有指示,它缺乏完美的 HSE 一致 Hsf 有约束力的序列。然而,在形成变化近来 HsfA2 依赖的 HSE 绑定在 hsfB1/B2b 植物被检测。这建议 HsfB1/B2b 可以在调整热吃惊反应的用以遮闭之物与班 A-Hsf 交往。Pdf 基因的鉴定作为 Hsf 依赖的否定规定的目标是为在关於生命、不能生活的回答的规定的 Hsf 的互联的第一条证据。 | Mukesh Kumar Wolfgang Busch Hannah Birke Birgit Kemmerling Thorsten Nurnberger Friedrich Schoffl | 2009 | Molecular Plant2009，2，1： | 15 |
| 6 | 干旱区胡杨叶片含水量和叶绿素含量特征显示文摘在阿拉干样区内,距河道不同距离选取40棵胡杨树(Populus euphratica)采样,使用相关分析方法探讨胡杨叶片相对含水量(fuel moisture content,FMC)、等效水厚度(equiv-alent water thickness,EWT)、叶绿素含量随距河道距离的空间差异,以及随地面温度的变化特征,并讨论了FMC、EWT和叶绿素含量之间的相关性。结果表明:FMC、EWT、叶绿素含量与河道距离有极显著的相关关系(P<0.01)。距河道越远,3项指标均随距河道距离的增加极显著的减少,其中EWT与距河道距离的相关性最大(-0.577)。温度变化对FMC和EWT均有极显著的影响(P<0.01),但对叶绿素含量影响不大(P>0.05)。因FMC、EWT的物理含义不同,它们的平均值在胡杨树个体尺度/水平上极显著相关,但在单片叶子尺度上FMC和EWT之间无显著相关(P>0.05),而胡杨树个体平均和单片叶子的EWT与叶绿素含量均极显著相关(P<0.01)。由于EWT与距河道距离和叶绿素含量的相关性极显著,而且对温度变化不敏感,因此,具有很好的开发应用潜力,建议将EWT作为干旱区河岸生态系统植被含水量遥感监测的一个指标。 | 牛婷 艾里西尔.库尔班 玉米提.哈力克 Philipp Gartner Birgit Kleinschmit 阿布都米吉提.阿布利克木 苏热亚古丽.艾米都力 刘桂林 | 2012 | 生态学杂志2012，31，6： | 15 |
| 7 | Long-term follow-up after complete ablation of Barrett's esophagus with argon plasma coagulation显示文摘AIM: To report the long-term outcome of patients after complete ablation of non-neoplastic Barrett's esophagus (BE) with respect to BE relapse and development of intraepithelial neoplasia or esophageal adenocarcinoma.METHODS: In 70 patients with histologically proven nonneoplastic BE, complete BE ablation was achieved by argon plasma coagulation (APC) and high-dose proton pump inhibitor therapy (120 mg omeprazole daily). Sixty-six patients (94.4%) underwent further surveillance endoscopy. At each surveillance endoscopy four-quadrant biopsies were taken from the neo-squamous epithelium at 2 cm intervals depending on the pre-treatment length of BE mucosa beginning at the neo-Z-line, and from any endoscopically suspicious lesion.RESULTS: The median follow-up of 66 patients was 51 mo (range 9-85 mo) giving a total of 280.5 patient years.A mean of 6 biopsies were taken during surveillance endoscopies. In 13 patients (19.7%) tongues or islands suspicious for BE were found during endoscopy. In 8 of these patients (12.1%) non-neoplastic BE relapse was confirmed histologically giving a histological relapse rate of 3% per year. In none of the patients, intraepithelial neoplasia nor an esophageal adenocarcinoma was detected.Logistic regression analysis identified endoscopic detection of islands or tongues as the only positive predictor of BE relapse (P = 0.0004).CONCLUSION: The long-term relapse rate of nonneoplastic BE following complete ablation with high-power APC is low (3% per year). | Ahmed Madisch Stephan Miehike Ekkehard Bayerdoerffer Birgit Wiedemann David Antos Anke Sievert Michael Vieth Manfred Stolte Heinrich Schulz | 2005 | World Journal of Gastroenterology2005，11，8： | 14 |
| 8 | Current developments in pediatric liver transplantation显示文摘In 1953, the pioneer of human orthotopic liver transplantation(LT), Thomas E Starzl, was the first to attempt an orthotopic liver transplant into a 3 years old patient suffering from biliary atresia. Thus, the first LT in humans was attempted in a disease, which, up until today, remains the main indication for pediatric LT(p LT). During the last sixty years, refinements in diagnostics and surgical technique, the introduction of new immunosuppressive medications and improvements in perioperative pediatric care have established LT as routine procedure for childhood acute and chronic liver failure as well as inherited liver diseases. In contrast to adult recipients, p LT differs greatly in indications for LT, allocation practice, surgical technique, immunosuppression and postoperative life-long aftercare. Many aspects are focus of ongoing preclinical and clinical research. The present review gives an overview of current developments and the clinical outcome of p LT, with a focus on alternatives to full-size deceased-donor organ transplantation. | Christina Hackl Hans J Schlitt Martin Loss Birgit Knoppke Michael Melter | 2015 | World Journal of Hepatology2015，7，11： | 13 |
| 9 | 基于变化轨迹探测的植被景观格局动态分析——以塔里木河下游生态输水区域为例显示文摘在遥感与GIS技术支持下,以2006、2007、2009、2010年Landsat-5/TM影像与2008年的CBERS/CCD影像为主要数据源,获得5a的植被/非植被类型图。在此基础上,提取并归纳5a间的植被变化轨迹:恒定植被、恒定非植被、转变为植被、转变为非植被、非稳定变化。利用景观格局分析软件FRAGSTATS 3.3计算了变化轨迹景观格局的3种景观指标。结果表明,2006—2010年植被面积减小,主要因为生态输水量减小、输水间隔较大,导致草本植被、乔灌木幼苗死亡;恒定非植被的比重最大,表明非植被类型是研究区的基质,其次是转变为非植被的比重,说明5a间植被的衰退程度要强于恢复程度;转变为植被与非稳定变化两种类型属于过渡性植被变化类型,受生态输水量、分布的制约严重;各种变化轨迹类型的形状规则较为稳定,其中以恒定非植被类型最稳定而非稳定变化类型最不稳定。 | 刘桂林 艾里西尔.库尔班 玉米提.哈力克 段含明 Philipp Gartner Birgit Kleinschmit 阿布都米吉提.阿布利克木 牛婷 | 2012 | 中国沙漠2012，32，5： | 12 |
| 10 | A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling显示文摘The stromal compartment of the tumor microenvironment consists of a heterogeneous set of tissue-resident and tumor-infiltrating cells,which are profoundly moulded by cancer cells.An outstanding question is to what extent this heterogeneity is similar between cancers affecting different organs.Here,we profile 233,591 single cells from patients with lung,colorectal,ovary and breast cancer(n=36)and construct a pan-cancer blueprint of stromal cell heterogeneity using different single-cell RNA and protein-based technologies.We identify 68 stromal cell populations,of which 46 are shared between cancer types and 22 are unique.We also characterise each population phenotypically by highlighting its marker genes,transcription factors,metabolic activities and tissue-specific expression differences.Resident cell types are characterised by substantial tissue specificity,while tumor-infiltrating cell types are largely shared across cancer types.Finally,by applying the blueprint to melanoma tumors treated with checkpoint immunotherapy and identifying a naive CD4+T-cell phenotype predictive of response to checkpoint immunotherapy,we illustrate how it can serve as a guide to interpret scRNA-seq data.In conclusion,by providing a comprehensive blueprint through an interactive web server,we generate the first panoramic view on the shared complexity of stromal cells in different cancers. | Junbin Qian Siel Olbrecht Bram Boeckx Hanne Vos Damya Laoui Emre Etlioglu Els Wauters Valentina Pomella Sara Verbandt Pieter Busschaert Ayse Bassez Amelie Franken Marlies Vanden Bempt Jieyi Xiong Birgit Weynand Yannick van Herck Asier Antoranz Francesca Maria Bosisio Bernard Thienpont Giuseppe Floris Ignace Vergote Ann Smeets Sabine Tejpar Diether Lambrechts | 2020 | Cell Research2020，30，9： | 11 |
| 11 | Osteoclast-like giant cell tumors of the pancreas and liver显示文摘Osteoclast-like giant cell tumors (OGCT) are rare abdominal tumors, which mainly occur in the pancreas. The neoplasms are composed of two distinct cell populations and frequently show an inhomogenous appearance with cystic structures. However, due to the rarity of these tumors, only very limited clinical data are available. Imaging features and sonographic appearance have hardly been characterized. Here we report on two cases of osteoclast-like giant cell tumors, one located within the pancreas, the other within the liver, in which OGCTs are extremely rare. Both patients were investigated by contrast sonography, which demonstrated a complex, partly cystic and strongly vascularized tumor within the head of the pancreas in the first patient and a large, hypervascularized neoplasm with calcifications within the liver in the second patient. The liver OGCT responded well to a combination of carboplatin, etoposide and paclitaxel. With a combination of surgical resection, radiofrequency ablation and chemotherapy, the patient’s survival is currently more than 15 mo, making him the longest survivor with an OGCT of the liver to date. | Juergen Bauditz Birgit Rudolph Wolfram Wermke | 2006 | World Journal of Gastroenterology2006，12，48： | 9 |
| 12 | 塔里木河下游阿拉干断面胡杨树高的分布和密度显示文摘通过小尺度生态监测与遥感数据分析获取塔里木河下游胡杨(Populus euphratica Oliv.)林现状信息,将胡杨个体对输水的响应实测数据和QuickBird影像信息进行对比和分析,“面”上宏观调查与“点”上典型研究相结合,集中对塔里木河下游阿拉干断面设立的100hm2长期监洲样方内的4500棵胡杨树进行了详细的调查。研究表明:胡杨密度随着离河岸距离增加而呈现降低的规律。不同树高的胡杨也呈一定规律分布。树高小于3m的幼树主要分布在距河道50m范围内;树高3-9m之间的胡杨在研究区中占绝对优势;树高大于9m的胡杨在距河道200m内分布比较均匀,200m之外分布稀少。 | 蔡富艳 玉米提·哈力克 艾尔肯·艾白不拉 阿布都米吉提·阿布力克木 Bodo Coenradie Birgit Kleinschmit | 2008 | 生态环境2008，17，3： | 8 |
| 13 | Evolution of particle number size distribution in an urban atmosphere during episodes of heavy pollution and new particle formation显示文摘This study discusses the evolution of particle number size distribution during episodes of heavy pollution and new particle formation in the urban atmosphere of Beijing to quantify the effects of dynamic processes (coagulation and condensation) on the particle number size distribution.During a heavy-pollution event,an extremely low number concentration of 3-10 nm particles (on average 46 cm-3) was observed.This is because nucleation-mode particles were easily removed by strong coagulational scavenging of larger particles under this condition.In addition,a large condensation sink (on average 0.13 s-1) restrained nucleation,which is one of the major sources of nucleation-mode particles.Conversely,during a new-particle formation event,the small condensation sink (0.01 s-1) of precursor facilitated nucleation.At the same time,preexisting particles had little ability to scavenge newly formed particles (around 1 nm) and allowed them to grow to a detectable size (larger than 3 nm currently).We suggest that the effects of dynamic processes (coagulation and condensation) on particle size distribution should be stressed under some extreme conditions of the relatively polluted urban atmosphere in addition to traffic and meteorological factors. | WU ZhiJun, HU Min YUE DingLi Birgit WEHNER Alfred WIEDENSOHLER | 2011 | Science China Earth Sciences2011，54，11： | 8 |
| 14 | Therapy-refractory gastrointestinal motility disorder in a child with c-kit mutations显示文摘Constipation and fecal impaction are frequent and distressing complaints in pediatric gastroenterology. Especially in neurologically handicapped children, treatment of severe forms of slow-transit constipation (STC) can be difficult. In the majority of cases, STC is of unknown etiology. However, in recent years, there is growing evidence that interstitial cells of Cajal (ICCs), which serve as electrical pacemakers and generate spontaneous electrical slow waves in the gastrointestinal tract, might play an important role in the pathophysiology of STC. It remains unclear whether morphological ICC alterations seen in affected patients are based on congenital developmental anomalies, or whether they are a consequence of long-term constipation with secondary damage of the gastrointestinal nervous system. To the best of our knowledge, we present the first case of a patient with histological alterations in ICC morphology who displayed multiple alterations of c-kit at the level of mRNA. The protein encoded by c-kit is the receptor tyrosine kinase Kit (CD117), which is crucial for development and function of ICCs. Therefore, these findings provide a new explanation for congenital alterations of ICC development that result in gastrointestinal motility disorders. | Christian Breuer Jun Oh Gerhard J Molderings Michael Schemann Birgit Kuch Ertan Mayatepek Rüdiger Adam | 2010 | World Journal of Gastroenterology2010，16，34： | 7 |
| 15 | 高对映选择性环氧化物水解酶产生菌的筛选及特性研究显示文摘从土壤中分离的芽孢杆菌BacillusmegateriumECU1 0 0 1所产环氧化物水解酶能高对映选择性水解缩水甘油苯基醚 (对映选择率E值可达 47 8) ,当转化率为 5 5 9%时 ,剩余的 (S) 缩水甘油苯基醚的光学纯度 (对映体过量值 ,ee)可达 99 5 % ;当底物浓度提高到 60mmol/L时 ,光学纯 (S) 缩水甘油苯基醚的收率达到 2 5 6% | 唐燕发 许建和 武慧渊 叶勤 Schulze Birgit | 2001 | 微生物学通报2001，28，5： | 7 |
| 16 | 一项在欧洲和中国进行的新型胃泌素释放肽前体(ProGRP)免疫检测多中心评估研究显示文摘背景在欧洲和中国进行Elecsys?胃泌素释放肽前体(ProGRP)免疫检测的多中心评估研究。方法在欧洲的3个中心和中国的2个中心,在肺癌中,通过不精密度、稳定性、方法学比较和鉴别诊断能力来评价该检测法。结果 5个分析物浓度的中间不精密度范围为变异系数:2.2%-6.0%。在不同储存条件下,血浆和血清样本均显示出良好的稳定性。在血浆中Elecsys?和ARCHITECT检测(斜率1.02,截距-2.72 pg/m L)之间表现出良好的相关性。同时,Elecsys?检测在血清和血浆样本之间表现出良好的相关性(斜率0.93,截距2.35 pg/m L;相关系数0.97)。ProGRP作为不受种族、年龄、性别或吸烟史相关影响的检测手段,可鉴别小细胞和非小细胞肺癌(NSCLC);截断值为84pg/m L时,曲线下面积为0.90,95%CI:0.87-0.93;敏感性为78.3%,特异性为95%。ProGRP浓度中位数在良性病变(38pg/m L)、其他恶性肿瘤(40 pg/m L)或NSCLC(39 pg/m L)中较低,而在3期以上慢性肾脏疾病中浓度较高(>100pg/m L)。结论 Elecsys?ProGRP检测在血清和血浆中稳定性增加,较现有检测法明显更具优势。ProGRP检测在中国的首次评价在不同种族中显示出相当的鉴别能力。 | Catharina M.KORSE Stefan HOLDENRIEDER Xiuyi ZHI Xiaotong ZAHNG Ling QIU Andrea GEISTANGER Marcus-Rene LISY Birgit WEHNL Daan van den BROEK José M.ESCUDERO Jens STANDOP Mu HU Rafael MOLINA | 2017 | 中国肺癌杂志2017，20，8： | 7 |
| 17 | Liver transplantation for malignancy:current treatment strategies and future perspectives显示文摘In 1967,Starzl et al performed the first successful liver transplantation for a patient diagnosed with hepatoblastoma.In the following,liver transplantation was considered ideal for complete tumor resection and potential cure from primary hepatic malignancies.Several reports of liver transplantation for primary and metastatic liver cancer however showed disappointing results and the strategy was soon dismissed.In1996,Mazzaferro et al introduced the Milan criteria,offering liver transplantation to patients diagnosed with limited hepatocellular carcinoma.Since then,liver transplantation for malignant disease is an ongoing subject of preclinical and clinical research.In this context,several aspects must be considered:(1)Given the shortage of deceased-donor organs,long-term overall and disease free survival should be comparable with results obtained in patients transplanted for nonmalignant disease;(2)In this regard,living-donor liver transplantation may in selected patients help to solve the ethical dilemma of optimal individual patient treatment vs organ allocation justice;and(3)Ongoing research focusing on perioperative therapy and antiproliferative immunosuppressive regimens may further reduce tumor recurrence in patients transplanted for malignant disease and thus improve overall survival.The present review gives an overview of current indications and future perspectives of liver transplantation for malignant disease. | Christina Hackl Hans J Schlitt Gabriele I Kirchner Birgit Knoppke Martin Loss | 2014 | World Journal of Gastroenterology2014，20，18： | 7 |
| 18 | Intracellular transport of hepatitis B virus显示文摘For genome multiplication hepadnaviruses use the tran-scriptional machinery of the cell that is found within the nucleus.Thus the viral genome has to be transported through the cytoplasm and nuclear pore.The intracy-tosolic translocation is facilitated by the viral capsid that surrounds the genome and that interacts with cellular microtubules.The subsequent passage through the nu-clear pore complexes(NPC) is mediated by the nuclear transport receptors importin α and β.Importin α binds to the C-terminus of the capsid protein that comprises a nuclear localization signal(NLS).The exposure of the NLS is regulated and depends upon genome maturation and/or phosphorylation of the capsid protein.As for oth-er karyophilic cargos using this pathway importin α inter-acts with importin β that facilitates docking of the import complex to the NPC and the passage through the pore.Being a unique strategy,the import of the viral capsid is incomplete in that it becomes arrested inside the nuclear basket,which is a cage-like structure on the karyoplas-mic face of the NPC.Presumably only this compartment provides the factors that are required for capsid disas-sembly and genome release that is restricted to those capsids comprising a mature viral DNA genome. | Michael Kann André Schmitz Birgit Rabe | 2007 | World Journal of Gastroenterology2007，13，1： | 6 |
| 19 | Induction of the AOX1D Isoform of Alternative Oxidase in A. thaliana T-DNA Insertion Lines Lacking Isoform AOX1A Is Insufficient to Optimize Photosynthesis when Treated with Antimycin A显示文摘植物呼吸被二条小径为电子转移描绘到 O2,也就是被连接到 ATP 生产的细胞色素小径(CP ) ,和其他的小径(AP ) ,没有伴随物 ATP,从 ubiquinol 的电子在哪儿,直接经由其他的 oxidase (AOX ) 转到 O2 生产。这条后者小径很好被适合在光过量电子处理,导致优化光合的性能。我们描绘了不表示主要 isoform 的 Arabidopsis thaliana 的 T-DNA-insertion 变异的线, AOX1A。处于标准生长条件,这些植物没由抗霉素 A 通过 CP 显示出电子流动的任何显型,而是限制,它导致 AOX1A 表示在野类型,在 aox1a 大美人异种的叶子导致了 AOX1D 的增加的表情。尽管有在异种的 AOX1D isoform 的增加的存在,抗霉素 A 引起了光合作用的抑制,增加了 ROS,并且当时,最终导致了放大的膜漏和坏死与相比野类型,它被禁止者仅仅在边际地影响。经由 CP 的电子流动什么时候被限制,因此出现 AOX1D 是不能的充分补偿 AOX1A 的损失。抑制的联合学习,联合了到代谢物介绍并且指向了 glycine decarboxylase 建筑群(GDC ) 的 P 蛋白质的表示分析,建议 aox1a 异种试图为 photorespiration 增加他们的能力。然而,给他们的缺乏,在当与抗霉素 A 对待时,任何一个 AOX1D 都不能充分补偿让 AOX1A 的缺乏优化光合作用的表示增加,是吸引人的。我们建议 aox1a 异种能进一步被用来有关对光合的性能和基因表示的 mitochondrial 氧化还原作用的影响证实当前的模型。 | Inga Strodtkotter Kollipara Padmasree Challabathula Dinakar Birgit Speth Pamela S. Niazi Joanna Wojtera Ingo Voss Phuc Thi Do Adriano Nunes-Nesi Alisdair R. Fernie Vera Linke Agepati S. Raghavendra Renate Scheibe | 2009 | Molecular Plant2009，2，2： | 5 |
| 20 | Is there an association of microscopic colitis and irritable bowel syndrome-A subgroup analysis of placebo-controlled trials显示文摘TO THE EDITOR
With great interest we read the recent retrospectice study by Barta et al (1) dealing with the clinical presentation of patients with microscopic colitis. They investigated in a cohort of 53 patients with microscopic colitis (46 with collagenous colitis, 7 with lymphocytic colitis)the relationship between microscopic colitis and both constipation and diarrhea. One of their mean finding was that abdominal pain, diarrhea and constipation was a common symptom complex of patients with microscopic colitis, thus the face of microcopic colitis resembles the subgroups of irritable bowel syndrome (IBS). | Ahmed Madisch Birgit Bethke Manfred Stolte Stephan Miehlke | 2005 | World Journal of Gastroenterology2005，11，41： | 4 |
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