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| 1 | Magnetic spin–orbit interaction of light显示文摘We study the directional excitation of optical surface waves controlled by the magnetic field of light.We theoretically predict that a spinning magnetic dipole develops a tunable unidirectional coupling of light to transverse electric(TE)polarized Bloch surface waves(BSWs).Experimentally,we show that the helicity of light projected onto a subwavelength groove milled into the top layer of a 1D photonic crystal(PC)controls the power distribution between two TE-polarized BSWs excited on both sides of the groove.Such a phenomenon is shown to be solely mediated by the helicity of the magnetic optical field,thus revealing a magnetic spin-orbit interaction of light.Remarkably,this magnetic optical effect is clearly observed via a near-field coupler governed by an electric dipole moment:it is of the same order of magnitude as the electric optical effects involved in the coupling.This opens up new degrees of freedom for the manipulation of light and offers desirable and novel opportunities for the development of integrated optical functionalities. | Mengjia Wang Hongyi Zhang Tatiana Kovalevich Roland Salut Myun-Sik Kim Miguel Angel Suarez Maria-Pilar Bernal Hans-Peter Herzig Huihui Lu Thierry Grosjean | 2018 | Light(Science & Applications)2018，7，1： | 15 |
| 2 | Circular RNAs in colorectal cancer:Possible roles in regulation of cancer cells显示文摘Colorectal cancer(CRC) is the third most commonly diagnosed cancer in the world and the fourth principal cause of cancer deaths worldwide. Currently, there is a lack of low cost and noninvasive screening tests for CRC, becoming a serious health problem. In this context, a potential biomarker for the early detection of CRC has recently gained attention. Circular RNAs(circ RNA), a re-discovered, abundant RNA specie, is a type of noncoding covalent closed RNAs formed from both exonic and intronic sequences. These circular molecules are widely expressed in cells, exceeding the abundance of the traditional linear m RNA transcript. They can regulate gene expression, acting as real sponges for mi RNAs and also regulate alternative splicing or act as transcriptional factors and inclusive encoding for proteins. However, little is known about circ RNA and its relationship with CRC. In this review, we focus on the biogenesis, function and role of these circ RNAs in relation to CRC, including their potential as a new biomarker. | María Isabel Taborda Sebastián Ramírez Giuliano Bernal | 2017 | World Journal of Gastrointestinal Oncology2017，9，2： | 13 |
| 3 | Effect of initial material bulk density and easily-degraded organic matter content on temperature changes during composting of cucumber stalk显示文摘To inactivate the potentially pathogenic microorganisms and safely utilize vegetable waste compost, ultra-high temperatures(> 70°C) should be maintained during the composting without having an inhibitory effect on maturity. This study investigated the influence of bulk density(part 1) and easily-degraded organic matter content(EDOMC, part 2) on temperature evolution during vegetable waste composting: Part 1: corn straw with different particle sizes was used to achieve different bulk densities in the composting material(BD1–BD3); Part 2: partial or total substitution of the corn straw by corn starch was carried out to obtain different EDOMC(ED1–ED4). The composting experiments were conducted in a labscale reactor(1.75 kg material) and lasted for 30 d. Temperature and CO2 emission were recorded daily, and the organic matter, lignocellulose, microbial activity, germination index(GI) and C/N of the samples were measured at different stages. The highest temperature(65.7°C) in part 1 occurred in the treatment with the bulk density of 0.35 g/cm3, which also had the longest thermophilic phase. Bulk density was found to seriously influence the utilization efficiency of O2 and heat transfer through materials, rather than heat production from organic matter degradation. In experiment part 2, the highest temperature was obtained with EDOMC of 45%(71.4°C). Therefore, adjusting the bulk density to 0.35 g/cm3 and the easily-degraded organic matter content of the initial material to 45% was the best combination for reaching temperatures above 70°C during composting, with no inhibitory effect on the maturity of the compost product. | Ruixue Chang Qiuyue Guo Qing Chen Maria Pilar Bernal Qian Wang Yanming Li | 2019 | Journal of Environmental Sciences2019，31，6： | 11 |
| 4 | 两种单氟磷酸钠牙膏预防乳牙龋病的2年临床研究显示文摘目的 :比较含氟浓度为 78.95 mmol/L (15 0 0 ppm)、磨料分别为碳酸钙及二氧化硅的二种单氟磷酸钠牙膏对儿童乳牙的临床防龋效果。方法 :采用随机双盲对照法 ,对四川省成都市 12 0 0名 4岁儿童进行了为期 2年的追踪研究。受试儿童被分为 3组 ,第 l组为含氟浓度 78.95 mmol/L、磨料为二氧化硅的单氟磷酸钠牙膏(MFP/Si O2 ) ,第 2组为含氟浓度 78.95 mmol/L、磨料为碳酸钙的单氟磷酸钠牙膏 (MFP/Ca CO3) ,第 3组为对照组 ,使用不含氟的碳酸钙牙膏。分析指标为乳牙龋面均 (dfs)增长数。结果 :998名儿童完成 2年的临床观察 ,1基线检查 3组的龋面均无显著性差异 ;2 l年后的龋面均增长数 :MFP/Si O2 组为 1.6 9± 3.12 ,MFP/Ca CO3组为1.5 3± 3.0 9,与对照组 2 .19± 4.12比较分别下降 30 .1%和 2 2 .8% ;3 2年后 MFP/Si O2 组和 MFP/Ca CO3组的龋面均增长数为 2 .98± 4.42及 2 .75± 4.33,与对照组 4.73± 5 .17比较分别下降 37%和 41.9% ,差异有显著性 ,两试验组之间统计学的差异无显著性。结论 :使用含 78.95 mmol/L氟浓度 ,磨料为二氧化硅或碳酸钙的单氟磷酸钠牙膏均有明显防龋效果 ,只要严格控制含氟牙膏的用量和加强管理 ,对发病率高的幼儿乳牙 ,不失为一种值得推广的安全而有效的防龋措施。 | 范旭 万呼春 胡德渝 Yun PoZhang Bernal Stewart James McCool Margaret Petrone William De Vizio Anthony Volpe | 2001 | 实用口腔医学杂志2001，17，6： | 8 |
| 5 | Conversion from calcineurin inhibitors to mTOR inhibitors stabilizes diabetic and hypertensive nephropathy after liver transplant显示文摘AIM: To investigate if conversion to the mammalian target of rapamycin inhibitors(mTORi) improves renal function in diabetic and/or hypertensive liver transplant patients immunosuppressed with tacrolimus or cyclosporine.METHODS: The study included 86 liver graft recipients immunosuppressed with mTORi treatment after orthotopic liver transplantation(OLT), including all liver recipients with worsening renal function before conversion to mTORi(n = 55 patients) and recipients with normal renal function who converted to m TORi for other reasons(n = 31 patients). We identified patients with diabetes mellitus(n = 28), arterial hypertension(n = 27), proteinuria(n = 27) and all three factors(n = 8)(some patients have hypertension and diabetes and no proteinuria). The primary endpoint was evolution in renal function defined as the development in plasma creatinine as a function of diabetes mellitus(DM), hypertension(HT) or proteinuria. We required elevated serum creatinine for at least two weeks to define renal dysfunction.RESULTS: Only patients that converted because of renal failure with plasma creatinine levels > 1.5 mg/dL showed an improvement of renal function(2.14 to 1.77 mg/dL)(P = 0.02). Patients with DM showed no improvement of serum creatinine levels(1.31 mg/dL to 1.37 mg/dL) compared with non DM patients(1.31 mg/dL to 1.15 mg/dL)(P = 0.01), HT patients(1.48 mg/dL to 1.5 mg/dL) with non HT patients(1.21mg/d L to 1.08 mg/dL) and patients with proteinuria(1.44 mg/dL to 1.41 mg/dL) and no proteinuria(1.31 mg/dL to 1.11 mg/dL). CONCLUSION: In OLT recipients with diabetes or hypertensive nephropathy, conversion to m TORi does not improve renal function but stabilizes plasma levels of creatinine. Proteinuria is not a contraindication to conversion to m TORi; it also stabilizes renal function. Conversion to m TORi should only be avoided in patients with diabetes, hypertension and proteinuria. | José M álamo Claudia Olivares Lydia Barrera Luis M Marín Gonzalo Suarez Carmen Bernal Juan Serrano Jordi Muntané Francisco J Padillo Miguel A Gómez | 2015 | World Journal of Transplantation2015，5，1： | 6 |
| 6 | Effect of human disturbance on the structure and regeneration of forests in the Nevado de Toluca National Park, Mexico显示文摘Sample plots were established in the principal forest types in the the Nevado de Toluca National Park, Mexico including those dominated by Pinus hartwegii, Abies religiosa, Quercus laurina and Alnus jorullensis. The vertical structure was defined by three strata in the coniferous forests and two strata in the broadleaved forests. Timber harvesting in Abies religiosa and Quercus laurina forests and fires generated by humans in Pinus hartwegii forests impeded the recruitment of saplings. Mature trees were also heavily impacted by logging in Pinus hartwegii forests. On the contrary, Alnus jorullensis forests were increasing due to the disturbance of Pinus and Quercus forests, as well abandoned crop lands within the park. A combination of logging, uncontrolled fire, and grazing appears to be compromising the recruitment of important tree species in this national park. These factors, together with human settlements, have also increased the proportion of early successional species. Changes in forest structure from human disturbance indicate a need to control these activities if conservation goals are not to be compromised. | Angel Rolando Endara Agramont Sergio Franco Maass Gabino Nava Bernal Juan Ignacio Valdez Hernández Todd S.Fredericksen | 2012 | Journal of Forestry Research2012，23，1： | 5 |
| 7 | The chemosensory appendage proteome of Amblyomma americanum (Acari: Ixodidae) reveals putative odorant-binding and other chemoreception-related proteins显示文摘Proteomic 分析在孤独的星的 2 个化学感应的附器上被做滴答响, Amblyomma americanum。蛋白质在在先 tarsi,包含嗅觉的 Hallers 机关,并且在触官,包括味觉的 sensilla,与在第三 tarsi 的蛋白质相比。另外,男性和女性滴答响被比较。蛋白质被顺序类似,并且由 3-dimensional 相同建模识别到已知的蛋白质。Proteomic 数据也与从 tick Rhipicephalus microplus 的器官特定的 transcriptomes 相比。在先 tarsi 快车没在第三 tarsi 或触官发现的 lipocalin。在先, tarsi 和触官富有地表示 2 蛋白质,它类似于昆虫有气味的东西绑定蛋白质(OBP ) 。与昆虫 OBP 相比, tick 象 OBP 一样序列缺乏半胱氨酸在 C 减 OBP 不在,并且 1 滴答响象 OBP 一样顺序有类似于 C 加 OBP 的另外的半胱氨酸。类似于抗菌素蛋白质 microplusin 的四蛋白质被发现:2 只表示了在在先 tarsi 并且 1 只在触官表示了。这些蛋白质缺乏 microplusin 铜绑定地点,而是他们被建模有一个重要的内部洞,潜在地一个 ligand 有约束力的地点。类似于 7 被发现差别的灰尘螨变应原 Der p7 和 Der f 的蛋白质在先在女性表示了 tarsi。只表示在的蛋白质在先, tarsi 有类似到否决权,它被知道涉及 ionotropic glutamate 受体聚类。这些结果组成象 OBP 一样蛋白质序列的第一份报告在滴答响并且点到几条研究大街在上滴答响化学感应的接收。 | Robert Renthal Leena Manghnani Sandra Bernal Yanyan Qu Wendell P. Griffith Kim Lohmeyer Felix O. Guerrero Ligia M.F. Borges Adalberto Perez de Leon | 2017 | Insect Science2017，24，5： | 4 |
| 8 | Clinical management of acute liver failure: Results of an international multi-center survey显示文摘AIM To assess the practice of caring for acute liver failure(ALF) patients in varying geographic locations and medical centers.METHODS Members of the European Acute Liver Failure Consortium completed an 88-item questionnaire detailing management of ALF. Responses from 22 transplantation centers in 11 countries were analyzed,treating between 300 and 500 ALF cases and performing over 100 liver transplants(LT) for ALF annually. The questions pertained to details of the institution and their clinical activity,standards of care,referral and admission,wardbased care versus intensive care unit(ICU) as well as questions regarding liver transplantation- including criteria,limitations,and perceived performance. Clinical data was also collected from 13 centres over a 3 mo period. RESULTS The interval between referral and admission of ALF patients to specialized units was usually less than 24 h and once admitted,treatment was provided by a multidisciplinary team. Principles of care of patients with ALF were similar among centers,particularly in relation to recognition of severity and care of the more critically ill. Centers exhibited similarities in thresholds for ICU admission and management of severe hepatic encephalopathy. Over 80% of centers administered n-acetyl-cysteine to ICU patients for non-paracetamolrelated ALF. There was significant divergence in the use of prophylactic antibiotics and anti-fungals,lactulose,nutritional support and imaging investigations in admitted patients and in the monitoring and treatment of intra-cranial pressure(ICP). ICP monitoring was employed in 12 centers,with the most common indications being papilledema and renal failure. Most patients listed for transplantation underwent surgery within an average waiting time of 1-2 d. Over a period of 3 mo clinical data from 85 ALF patients was collected. Overall patient survival at 90-d was 76%. Thirty six percent of patients underwent emergency LT,with a 90% post transplant survival to hospital discharge,42% survived with medical management alone. CONCLUSION Alongside similarities in principles of care of ALF patients,major areas of divergence were present in key areas of diagnosis,monitoring,treatment and decision to transplant. | Liane Rabinowich Julia Wendon William Bernal Oren Shibolet | 2016 | World Journal of Gastroenterology2016，22，33： | 3 |
| 9 | The rendezvous technique for the treatment of choledocholithiasis显示文摘 | Mari M. Calvo Luis Bujanda I?aki Heras José L. Cabriada Antonio Bernal Victor Orive José Miguelez | 2001 | Gastrointestinal Endoscopy2001，，4： | 2 |
| 10 | Probabilistic Seismic Risk Assessment in Manizales,Colombia: Quantifying Losses for Insurance Purposes显示文摘A fully probabilistic seismic risk assessment was developed in Manizales, Colombia, considering assets of different types. The first type includes elements that are part of the water and sewage network, and the second type includes public and private buildings. This assessment required the development of a probabilistic seismic hazard analysis that accounts for the dynamic soil response,assembling high resolution exposure databases, and the development of damage models for different types of elements. The economic appraisal of the exposed assets was developed together with specialists of the water utilities company of Manizales and the city administration. The risk assessment was performed using several Comprehensive Approach to Probabilistic Risk Assessment modules as well as the R-System, obtaining results in terms of traditional metrics such as loss exceedance curve, average annual loss, and probable maximum loss. For the case of pipelines, repair rates were also estimated. The results for the water and sewage network were used in activities related to the expansion and maintenance strategies, as well as for the exploration of financial retention and transfer alternatives using insurance schemes based on technical,probabilistic, and prospective damage and loss estimations.In the case of the buildings, the results were used in the update of the technical premium values of the existing collective insurance scheme. | Mario A. Salgado-Gálvez Gabriel A. Bernal Daniela Zuloaga Mabel C. Marulanda Omar-Darío Cardona Sebastián Henao | 2017 | International Journal of Disaster Risk Science2017，8，3： | 2 |
| 11 | Toll‐Like Receptors and Cytokines are Upregulated during H elicobacter pylori Infection in Children显示文摘 | Hugo Lagunes‐Servin Javier Torres Carmen Maldonado‐Bernal Martha Pérez‐Rodríguez Sara Huerta‐Yépez Armando Madrazo de la Garza Leopoldo Mu?oz‐Pérez Lourdes Flores‐Luna Guillermo Ramón‐García Margarita Camorlinga‐Ponce | 2013 | Helicobacter2013，，6： | 2 |
| 12 | Diabetes mellitus, revascularization and outcomes in elderly patients with myocardial infarction-related cardiogenic shock显示文摘Background The prognostic role of diabetes mellitus(DM)in elderly patients with myocardial infarction-related cardiogenic shock(MI-CS)remains controversial.Little information exists about the impact of intensive cardiac care unit(ICCU)and revascularization on outcomes of elderly patients with MI-CS.We aimed to assess the prognostic impact of DM according to age in patients with MI-CS,and to analyze the impact ICCU management and revascularization on in-hospital mortality in MI-CS patients at older ages.Methods Discharge episodes with diagnosis of CS associated with MI were selected from the Spanish National Health System’s Basic Data Set.Centers were classified according to their availability of ICCU.Main outcome measured was in-hospital mortality.Results A total of 23,590 episodes of MI-CS were identified,of whom 12,447(52.8%)were in patients aged≥75 years.The impact of DM on in-hospital mortality was different among age subgroups.While in younger patients,DM was associated to a higher mortality risk(0.52 vs.0.47,OR=1.12,95%CI:1.06–1.18,χ^2<0.001),this association became non-significant in older patients(0.76 vs.0.81,χ^2=0.09).Adjusted mortality rate of MI-CS aged≥75 years was lower in patients admitted to hospitals with ICCU(adjusted mortality rate:74.2%vs.77.7%,P<0.001)and in patients undergoing revascularization(74.9%vs.77.3%,P<0.001).Conclusions Prognostic impact of DM in patients with MI-CS was different according to age,with a significantly lower impact at older ages.The availability of ICCU and revascularization were associated with better outcomes in these complex patients. | Miquel Gual Albert Ariza-Solé María García Márquez Cristina Fernández JoséL Bernal Francesc Formiga María-Isabel Barrionuevo JoséC Sánchez-Salado Victòria Lorente Júlia Pascual Isaac Llaó Oriol Alegre Angel Cequier Javier Elola | 2020 | Journal of Geriatric Cardiology2020，17，10： | 2 |
| 13 | Characterisation of Ba(OH) 2 –Na 2 SO 4 –blast furnace slag cement-like composites for the immobilisation of sulfate bearing nuclear wastes显示文摘 | Neda Mobasher Susan A. Bernal Oday H. Hussain David C. Apperley Hajime Kinoshita John L. Provis | 2014 | Cement and Concrete Research2014，，： | 2 |
| 14 | Lessons from look-back in acute liver failure? A single centre experience of 3300 patients显示文摘 | William Bernal Anna Hyyrylainen Amit Gera Vinod K. Audimoolam Mark J.W. McPhail Georg Auzinger Mohammed Rela Nigel Heaton John G. O’Grady Julia Wendon Roger Williams | 2013 | Journal of Hepatology2013，，1： | 2 |
| 15 | Diagnostics in assisted human reproduction显示文摘 | Juan Manuel Montoya Alejandra Bernal Claudia Borrero | 2002 | Reproductive BioMedicine Online2002，，2： | 2 |
| 16 | Diet Energy Requirements of Growing Holsteins显示文摘 | D.E. Johnson G. Bernal | 1998 | Journal of Dairy Science1998，，3： | 2 |
| 17 | Thermal bridging of graphene nanosheets via covalent molecular junctions: A non-equilibrium Green's functions-density functional tightbinding study显示文摘Despite the uniquely high thermal conductivity of graphene is well known,the exploitation of graphene into thermally conductive nanomaterials and devices is limited by the inefficiency of thermal contacts between the individual nanosheets.A fascinating yet experimentally challenging route to enhance thermal conductance at contacts between graphene nanosheets is through molecular junctions,allowing covalently connecting nanosheets,otherwise interacting only via weak Van der Waals forces.Beside the bare existence of covalent connections,the choice of molecular structures to be used as thermal junctions should be guided by their vibrational properties,in terms of phonon transfer through the molecular junction.In this paper,density functional tight-binding combined with Green's functions formalism was applied for the calculation of thermal conductance and phonon spectra of several different aliphatic and aromatic molecular junctions between graphene nanosheets.Effects of molecular junction length,conformation,and aromaticity were studied in detail and correlated with phonon tunnelling spectra.The theoretical insight provided by this work can guide future experimental studies to select suitable molecular junctions,in order to enhance the thermal transport by suppressing the interfacial thermal resistances.This is attractive for various systems,including graphene nanopapers and graphene polymer nanocomposites,as well as related devices.In a broader view,the possibility to design molecular junctions to control phonon transport currently appears as an efficient way to produce phononic devices and controlling heat management in nanostructures. | Diego Martinez Gutierrez Alessa ndro Di Pierro Alessa ndro Pecchia Leon ardo Medra no San donas Rafael Gutierrez Mar Bernal Bohayra Mortazavi Gianaurelio Cuniberti Guido Saracco Alberto Fina | 2019 | Nano Research2019，12，4： | 2 |
| 18 | Microhabitat heterogeneity associated with Vanilla spp.and its influences on the microbial community of leaf litter and soil显示文摘The impact of forest microhabitats on physiochemical properties of the soil and that of microbial communities on tropical soils remain poorly understood.To elucidate the effect of tropical forest stand on leaf litter and soil microbial communities,we studied enzyme activities,microbial biomass,and diversity in three distinct microhabitats in terms of plant richness,diameter at breast height(DBH),and physiochemical properties of soil and litter,each associated with a different Vanilla sp.In the soil,positive correlations were found between electrical conductivity(EC)and total organic carbon(TOC)with phosphatase activity,and between nitrogen(N)and water-soluble carbon(WSC)content with urease activity(UA).In the litter,the water content was positively correlated with bacterial and fungal biomass,and N and WSC contents were positively correlated with fungal biomass.Positive correlations were found between plant richness and UA in the soil,plant richness and fungal biomass in the soil and litter,and DBH and fungal biomass in the litter.Amplicon sequencing revealed differences between microhabitats in the relative abundance of some fungal and bacterial taxa and in the bacterial community composition of both litter and soil.Bacterial richness and diversity were different between microhabitats,and,in litter samples,they were negatively correlated with DBH and plant richness,respectively.By contrast,none of the soil and litter physiochemical properties were significantly correlated with microbial diversity.Our results show that significant shifts in enzyme activity,microbial biomass,and diversity in the microhabitats were driven by key abiotic and biotic factors depending on the soil or litter sample type. | Gabriela Montes de Oca-Vasquez Frank Solano-Campos Bernal Azofeifa-Bolanos Amelia Paniagua-Vasquez Jose Vega-Baudrit Antonio Ruiz-Navarro Ruben Lopez-Mondejar Felipe Bastida | 2020 | Soil Ecology Letters2020，2，3： | 2 |
| 19 | Acute liver failure显示文摘 | William Bernal Georg Auzinger Anil Dhawan Julia Wendon | 2010 | The Lancet2010，，9736： | 2 |
| 20 | 一种基于REC.2020高清色域的视频级显微高动态范围成像方法显示文摘高动态范围成像已经成为数字显微镜发展的一大趋势。目前视频级高动态范围显微成像技术由于计算复杂度较高,还无法做到实时处理和显示。提出利用高清电视领域中的REC.2020色域变换,结合GPU实时加速处理技术,成功实现了高动态范围显微图像视频流的实时显示,图像具有良好的色彩还原性和细节恢复性。实验结果表明,设计的算法不仅能够提供稳定的高清、高动态范围视频,其细节和色彩还原性也有了很大的提高,突破了传统的高动态范围图像技术在成像速度和质量方面的限制。 | 郑驰 BERNAL Salvador Garcia 张克奇 毛磊 刘旭 | 2019 | 光学仪器2019，41，3： | 2 |
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