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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation. | Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 5 |
| 3 | 超声波诊断宫颈功能不全及其治疗显示文摘宫颈功能不全(ZI)临床定义很不一致,从无痛性的宫颈内口扩张,伴晚期流产及早产直至宫颈稍变短、变软而仅外口扩张,当然早产率也相应较低。ZI的发病率估计约为0.2~7/1,000例妊娠。过去诊断ZI多靠回顾性分析或阴道检查时的偶然发现。因此,病人通常得不到及时治疗或又过早进行了不必要的手术,换言之宫颈环扎的指征不够明确。至于ZI是否必定导致晚期流产及早产,各家说法不一,Paerniek及Wood通过4,689例的检查认为ZI可以引起早产。 | Berg D 刘梦梅 | 1990 | 国外医学(妇产科学分册)1990，17，4： | 3 |
| 4 | Vulnerability of the nigrostriatal system as detected by transcranial ultrasound显示文摘 | Berg D Becker G Zeiler B | 1999 | Neurology1999，53，： | 2 |
| 5 | Bacterial translation from the intestines显示文摘 | Berg R D | 1979 | Exp Anim1979，34，： | 2 |
| 6 | Acute infectious bursal disease in poultry:immunological and molecular basis of antigenicity of a highly virulent strain显示文摘 | Vanden Berg T P Gonze M Morales D | 1991 | Avian Pathology1991，25，： | 2 |
| 7 | Brain iron pathways and their relevance to Parkinson's disease显示文摘 | Berg D Gerlaeh M Youdim MB | 2001 | J Neurochem2001，79，2： | 1 |
| 8 | Real-time finite element modeling for surgery simulation: an application to virtual suturing显示文摘 | BERKLEY J TURKIYYAH G BERG D | 2004 | IEEE Transactions On Visualization And Computer Graphics2004，10，3： | 1 |
| 9 | The role of the cytoskeleton in cellular adhesion molecule expression in tumor necrosis factor - stimulated endothelial cells 显示文摘 | VANDEN BERG E REID M D EDWARDS J D | 2004 | Cell Biochem2004，91，5： | 1 |
| 10 | Tumor - infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T - cell response against tumor - associated antigens and survival显示文摘 | NAGORSEN D VOIGT S BERG E | 2007 | J Transl Med2007，5，29： | 1 |
| 11 | Sediment capping in eutrophic lakes: Efficiency of undisturbed calcite barriers immobilize phosphorus 显示文摘 | Berg U Neumann T Donnert D | 2004 | Applied Geochemistry2004，19，11： | 1 |
| 12 | Prognostic value of heart rate variability and ventricular arrhythmias during 13-year follow-up in patients with mild to moderate heart failure显示文摘 | Smilde TDJ van D J van den Berg MP | 2009 | Clin Res Cardiol2009，98，4： | 1 |
| 13 | Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma显示文摘 | Kluiver J van den Berg A de Jong D | 2007 | Oncogene2007，26，26： | 1 |
| 14 | Detection of breast cancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breast cancer risk显示文摘 | Berg WA Zhang Z Lehrer D | 2012 | JAMA2012，307，13： | 1 |
| 15 | Medical students' self-reported empathy and simulated patients' assessments of student empathy:an analysis by gender and ethnicity显示文摘 | Berg K Majdan JF Berg D | 2011 | Acad Med2011，86，8： | 1 |
| 16 | Normal Variants and Frequent Marrow Alterations that Simulate Bone Marrow Lesions at MR Imaging显示文摘 | Bruno C. Vande Berg Frédéric E. Lecouvet Christine Galant Baudouin E. Maldague Jacques Malghem | 2005 | Radiologic Clinics of North America2005，，： | 1 |
| 17 | Antenatal proton MR spectroscopy of the human brain in vivo显示文摘 | Heerschap A Kok R D van den Berg P P | 2003 | Child Nerv Syst2003，19，78： | 1 |
| 18 | Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2显示文摘 | GUPTA A RHODES GJ BERG D T | 2007 | Am J Physiol Renal Physiol2007，293，： | 1 |
| 19 | Career patterns and job satisfaction of canadian nurses education显示文摘 | Barrett MC Golden berg D Fauxs | 1992 | Journal of Advanced Nursing1992，12，8： | 1 |
| 20 | The protective efficacy of polyvalent pneumococcal polysaccharide vaccine 显示文摘 | Shapiro E D Berg A T Austrian R | 1991 | N Engl J Med1991，325，21： | 1 |
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