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| 1 | Determinants of the impact of blood pressure variability on neurological outcome after acute ischaemic stroke显示文摘Introduction: Increased blood pressure variability (BPV) is detrimental after acute ischaemic stroke, but the interaction between BPV and neuroimaging factors that directly influence stroke outcome has not been explored. Methods: We retrospectively reviewed inpatients from 2007 to 2014 with acute anterior circulation ischaemic stroke, CT perfusion and angiography at hospital admission, and a modified Rankin Scale (MRS) 30- 365 days after stroke onset. BPV indices included SD, coefficient of variation and successive variation of the systolic blood pressure between 0 and 120 hours after admission. Ordinal logistic regression models were fitted to MRS with predictor variables of BPV indices. Models were further stratified by CT perfusion volumetric measurements, proximal vessel occlusion and collateral score. Results: 110 patients met the inclusion criteria. The likelihood of a 1-point rise in the MRS increased with every 10 mm Hg increase in BPV (OR for the 3 BPV indices ranged from 2.27 to 5.54), which was more pronounced in patients with larger ischaemic core volumes (OR 8.37 to 18.0) and larger hypoperfused volumes (OR 6.02 to 15.4). This association also held true for patients with larger mismatch volume, proximal vessel occlusion and good collateral vessels. Conclusions: These results indicate that increased BPV is associated with worse neurological outcome after stroke, particularly in patients with a large lesion core volume, concurrent viable ischaemic penumbra, proximal vessel occlusion and good collaterals. This subset of patients, who are often not candidates for or fail acute stroke therapies such as intravenous tissue plasminogen activator or endovascular thrombectomy, may benefit from interventions aimed at reducing BPV. | Adam de Havenon Alicia Bennett Gregory J Stoddard Gordon Smith Lee Chung Steve O’Donnell J Scott McNally David Tirschwell Jennifer J Majersik | 2017 | Stroke & Vascular Neurology2017，2，1： | 6 |
| 2 | The endoscopic assessment of esophagitis: A progress report on observer agreement显示文摘 | D Armstrong JR Bennett AL Blum J Dent FT De Dombal JP Galmiche L Lundell M Margulies JE Richter SJ Spechler GN Tytgat L Wallin | 1996 | Gastroenterology1996，，1： | 2 |
| 3 | Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes显示文摘 | De Waal Malefyt R Abrams J Bennett B | 1991 | The Journal of Experimental Medicine1991，174，5： | 1 |
| 4 | ACC/AHA clinical performance measures for adults with chronic heart failure : a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures ( Writing Committee to Develop Heart Failure Clinical Performance Measures) endorsed by the Heart Failure Society of America 显示文摘 | Bonow RO Bennett S Casey DE | 2005 | J Am Coll Cardiol2005，46，6： | 1 |
| 5 | Pre- and intraoperative variables affecting early outcomes in elderly patients undergoing pancreaticoduodenectomy显示文摘 | de la Fuente SG Bennett KM Pappas TN | 2011 | HPB(Oxford)2011，13，12： | 1 |
| 6 | Recommendations for surveillance of transmitted HIV drug resistance in countries scaling up antiretroviral treatment 显示文摘 | Bennett DE Myatt M Bertagnolio S | 2008 | Antivir Ther2008，13，2： | 1 |
| 7 | Nephrotoxicity of immunosuppressive drugs:long-term consequences and challenges for the future显示文摘 | de Mattos AM Olyaei AJ Bennett WM | | 0，，02： | 1 |
| 8 | Oral Candida in HIV infection and AIDS: new perspectives/new approaches显示文摘 | Coleman DC Bennett DE Sullivan DJ | 1993 | Crit Rev Microbiol1993，19，： | 1 |
| 9 | Drug resistance muta- tions for surveillance of transmitted HIV-1 drug-resistance:2009 update 显示文摘 | Bennett DE Camacho RJ Otelea D | 2009 | PLoS One2009，4，3： | 1 |
| 10 | In vivo insulin sensitivity in the rat determined by euglycemic clamp显示文摘 | Kraegen EW James DE Bennett SP | 1983 | Am J Physiol1983，245，1： | 1 |
| 11 | Nephrotoxicity of immuno-suppressive drugs:long-term consequences and challenges for the fu-ture显示文摘 | De Mattos A M Olyaei A J Bennett W M | 2000 | Am J Kidney Dis2000，35，2： | 1 |
| 12 | Study of composition,stabilization and processing of wheat germ and maize industrial by-products显示文摘 | de Vasconcelos M C B M Bennett R Castro C | 2013 | Industrial Crops and Products2013，，2： | 1 |
| 13 | Drug resistance muta-tions for surveillance of transmitted HIV-1 drug-resistance: 2009 update 显示文摘 | Bennett DE Camaeho R Otelea D et 01 | 2009 | PLoS One2009，4，3： | 1 |
| 14 | Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies显示文摘 | Olyaei AJ de Mattos AM Bennett WM | 2001 | Curr Opin Crit Care2001，7，3： | 1 |
| 15 | Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor显示文摘 | Lebron JA Bennett MJ Vaughn DE | 1998 | Cell1998，93，1： | 1 |
| 16 | Recommendations for surveillance of transmitted HIV drug resistance in countries scaling up antiretroviral treatment 显示文摘 | Bennett DE Myatt M Bertagnolio S | 2008 | Antivir Ther2008，132，： | 1 |
| 17 | A practical guide to the management of hypertension in renal transplant recipients 显示文摘 | Olyaei AJ de Mattos AM Bennett WM | 1999 | Drugs1999，58，6： | 1 |
| 18 | Nephrotoxicity of immunosuppressive drugs:long-term consequences and challenges for the future显示文摘 | de Mattos AM Olyaei AJ Bennett WM | 2000 | Am J Kidney Dis2000，35，2： | 1 |
| 19 | Drug resistance mutations for surveillance of transmitted HIV-1 drug-resistance: 2009 update 显示文摘 | Bennett DE Camacho RJ Otelea D | 2009 | PLoS One2009，4，3： | 1 |
| 20 | Effect of urinary diversion on the recovery of micturition reflexes after spinal cord injury in the rat显示文摘 | Kruse MN Bennett B De Groat WC | 1994 | J Urol1994，151，4： | 1 |
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