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| 1 | Neutrophil-to-lymphocyte ratio in ocular diseases: a systematic review显示文摘AIM: To summarize the results of studies investigating neutrophil-to-lymphocyte ratio(NLR) and to identify the role of NLR in ocular diseases. METHODS: With the aim of identifying the studies related to NLR, a search was conducted on http://gffzz16a62c593b5540cehxoc6b9o0vunf6fqx.ffgz.tsg.suse.edu.cn/pubmed by utilizing the key words 'neutrophil lymphocyte ratio, ocular diseases, and eye diseases' up to February 2018. All of the original articles were assessed according to date of publications, countries, clinics and topics. Studies about ocular inflammatory diseases were evaluated according to their qualifications, review methods and results. RESULTS: A total of 4473 publications, including original research articles and reviews were screened. The number of publications was shown a regular logarithmic increase over the years. The majority of studies were performed by clinics in Turkey and many of these publications were performed by oncology and cardiology clinics. A total of 75 publications were identified to be about ocular diseases. CONCLUSION: Elevated NLR as a cheap, reproducible, and readily available marker could be used as a diagnostic and/or prognostic marker in ocular diseases. | Bengi Ece Kurtul Pinar Altiaylik Ozer | 2019 | International Journal of Ophthalmology(English edition)2019，12，12： | 6 |
| 2 | Frequency,types,and treatment of anemia in Turkish patients with inflammatory bowel disease显示文摘AIM to specify the type and prevalence of anemia along with a treatment approach for inflammatory bowel disease(IBD).METHODS We conducted a retrospective study on 465 patients who were diagnosed with IBD and followed up at our hospital from June 2015 to June 2016 [male: 254, female: 211; average age: 47 ± 14.4; Crohn's disease(CD): 257, Ulcerative Colitis(UC): 208]. Epidemiological and clinical data, such as sex, age, age of diagnosis, type of IBD, disease extension, disease behavior and duration, treatments for IBD and anemia, and surgical history were obtained for each patient. Per World Health Organization guidelines, anemia was diagnosed for males if hemoglobin values were less than 13 g/dL and for females if hemoglobin values were less than 12 g/d L.RESULTS We determined that 51.6% of the patients had anemia, which was more frequent in women then men(64% vs 41.3%, P < 0.001). Anemia frequency was higher in CD cases(57.6%) than in UC cases(44.2%)(P = 0.004). CD involvements were as follows: 48.2% in ileal involvement, 19% in colonic involvement, and 32.8% in ileocolonic involvement. Furthermore, 27.5% of UC patients had proctitis(E1) involvement, 41% ofthem had involvement in left colitis(E2), and 31.5% had pancolitis involvement. There was no significant relationship between anemia frequency and duration of disease(P = 0.55). Iron deficiency anemia(IDA) was the most common type of anemia in this cohort. Moreover, because anemia parameters have not been evaluated during follow-up of 15.3% of patients, the etiology of anemia has not been clarified. Fifty percent of patients with anemia received treatment. Twentythree percent of IDA patients had oral iron intake and forty-one percent of IDA patients had parenteral iron treatment. Fifty-three percent of patients who were suffering from megaloblastic anemia received B12/folic acid treatment.CONCLUSION We found out that almost half of all IBD patients(51.6%) had anemia, the most frequent of which was IDA. Almost half of these patients received treatment. We should increase the treatment rate in our IBD patients that have anemia. | Goksel Bengi Hatice Keyvan Seda Bayrak Durmaz Hale Akpinar | 2018 | World Journal of Gastroenterology2018，24，36： | 4 |
| 3 | Clinical and impression cytology findings of amniotic membrane and oral mucosal membrane transplantation for the management of socket contracture显示文摘AIM:To investigate and compare the cytopathological and clinical effects of amniotic membrane transplantation(AMT)and oral mucosal membrane transplantation(OMMT)in socket contraction.METHODS:Twelve patients who could not be fitted with ocular prosthesis due to socket contracture were included in this study.Seven patients underwent AMT and 5 patients underwent OMMT.Thirteen patients who had healthy sockets were included as control group.Depth of inferior fornix,degree of inflammation,extent of the socket contracture and socket volume were measured in the preoperative period and at sixth and twelfth weeks postoperatively.Impression cytology of conjunctival fornices and tear transforming growth factor beta-1(TGFβ1)levels were determined.RESULTS:In the AMT group,socket volume and lower fornix depth values were significantly higher(P=0.030and P=0.004 respectively)and inflammation levels and impression cytology stages(P=0.037 and P=0.022respectively)were significantly lower in postoperative period compared to preoperative period.In the OMMT group,no statistical differences were found in terms of clinical parameters,inflammation levels and impression cytology stages of preoperative versus postoperative values.Preoperative tear TGFβ1 levels were higher in AMT and OMMT groups compared to the control group(25.5 ng/mL,26.3 ng/mL and 21.7 ng/mL respectively).Decreased tear TGFβ1 levels were observed in both the AMT and OMMT groups postoperatively(median decrease value=2.1 ng/mL and 2.7 ng/mL respectively).CONCLUSION:AMT is associated with postoperative improvement in inferior fornix depth,socket volume,inflammation and impression cytology levels and may bea more proper alternative method than OMMT in the management of socket contracture. | Bengi Ece Kurtul Ugur Erdener Mehmet Cem Mocan Murat Irkec Mehmet Orhan | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 3 |
| 4 | Safety and efficacy of sorafenib for the treatment of recurrent hepatocellular carcinoma after liver transplantation显示文摘 | Abhijeet Waghray Bengi Balci Galal El‐Gazzaz Richard Kim Robert Pelley KV Narayanan Menon Bassam Estfan Carlos Romero‐Marrero Federico Aucejo | 2013 | Clin Transplant2013，，4： | 3 |
| 5 | Robust molecular detection of the new Tomato brown rugose fruit virus in infected tomato and pepper plants from Turkey显示文摘Tomato brown rugose fruit virus(ToBRFV)causes severe fruit loss in tomato(Solanum lycopersicum)and pepper(Capsicum annuum)plants.It is an emerging Tobamovirus that is spreading globally.The major challenge is to develop a reliable method for the detection of the virus,and to better characterize the symptoms it causes.The aims of this study,therefore,were to characterize the symptom development on tomato and pepper plants,and to establish a reliable detection method for the virus.Following infection of the tomato and pepper plants with ToBRFV,the leaves turned chlorotic,mosaic or mottled,while the fruit became rugose,necrotic and marbled,and showed discoloration with yellow or brown spots.Transmission electron microscopy(TEM)revealed single rod-like virus particles characteristic of the Tobamoviruses.Classical reverse transcription PCR(RT-PCR)and quantitative PCR(qPCR)with specific primers and probes confirmed that the virus is ToBRFV.We found that the resistance genes from tomato,Tm-2^(2),and pepper,L1,L2,L3 and L4,did not confer resistance to ToBRFV.Here,we present a PCR-based method as a diagnostic test for detecting ToBRFV in infected seeds.This method will help to prevent further spread of the virus in commercial seeds. | Hakan FIDAN Pelin SARIKAYA Kubra YILDIZ Bengi TOPKAYA Gozde ERKIS Ozer CALIS | 2021 | Journal of Integrative Agriculture2021，20，8： | 2 |
| 6 | Determination of lamivudine and zidovudine in binary mixtures using first derivative spectrophotometric, first derivative of the ratio-spectra and high-performance liquid chromatography-OV methods 显示文摘 | BENGI U SIBEL A O | 2002 | Analytica Chimica Acta2002，466，1： | 1 |
| 7 | An outbreak of bovine tu- berculosis in a free-living African buffalo (Syncems caffer-spar- mlan) population in the Kruger National Park: a preliminary report 显示文摘 | Bengis R G Kriek N P Keet D F | 1996 | Onderstepoort J Vet Res1996，63，1： | 1 |
| 8 | Taking on the curse of dimensionality in jointdistributions using neural networks显示文摘 | Bengio S Bengi Y | 2000 | IEEE Transactions onNeural Networks2000，11，3： | 1 |
| 9 | Effects of hyperbaric oxygen during experimental tooth movement显示文摘 | Gokce S Bengi AO Akin E | 2008 | Angle Orthod2008，78，2： | 1 |
| 10 | Rapid canine distalization using distraction of the periodontal ligament:a preliminary clinical validation of the original technique显示文摘 | Sayin S Bengi AO Gurton AU | 2004 | Angle Orthod2004，74，3： | 1 |
| 11 | Electrochemical study of fluvaslatin sodium-analytical application to pharmaceutical dosage forms, human serum, and simulated gastric juice显示文摘 | Sibel A Ozkan Bengi Uslu | 2002 | Analytical and Bioanalytical Chemistry2002，372，4： | 1 |
| 12 | Antioxidant activity andproline content of leaf extracts from Dorystoechas hastate显示文摘 | Arife A K Bengi E Yelda C E | 2008 | Food Chemistry2008，111，： | 1 |
| 13 | Bovine tuberculosis in southern African wildlife, a multi-species host-pathogen system 显示文摘 | Renwick AR White PC Bengis RG | 2007 | Epidemiol Infect2007，135，4： | 1 |
| 14 | Diffusion tensor imaging and tractography of median nerve normative diffusion values显示文摘 | Neslihan K Bengi G Zeynep F | 2007 | AJR2007，189，4： | 1 |
| 15 | Retrorectal tumors:A challenge for the surgeons显示文摘Retrorectal or presacral tumors are rare lesions located in the presacral area and considered as being derived from multiple embryological remnants.These tumors are classified as congenital,neurogenic,osseous,inflammatory,or miscellaneous.The most common among these are congenital benign lesions that present with non-specific symptoms,such as lower back pain and change in bowel habit.Although congenital and developmental tumors occur in younger patients,the median age of presentation is reported to be 45 years.Magnetic resonance imaging plays a crucial role in treatment management through accurate diagnosis of the lesion,the evaluation of invasion to adjacent structures,and the decision of appropriate surgical approach.The usefulness of preoperative biopsy is still debated;currently,it is only indicated for solid or heterogeneous tumors if it will alter the treatment management.Surgical resection with clear margins is considered the optimal treatment;described approaches are transabdominal,perineal,combined abdominoperineal,and minimally invasive.Benign retrorectal tumors have favorable long-term outcomes with a low incidence of recurrence,whereas malignant tumors have a potential for distant organ metastasis in addition to local recurrence. | Bengi Balci Alp Yildiz Sezai Leventoğlu Bulent Mentes | 2021 | World Journal of Gastrointestinal Surgery2021，13，11： | 1 |
| 16 | Rapid canine distalization using distraction of the periodontd ligament: a preliminary clinical validation of the original technique显示文摘 | Sayin S Bengi AO Gurtan AU | 2004 | Angle Orthod2004，74，3： | 1 |
| 17 | The Use of RAPD Markers on Penaeus Prawn Breeding Program显示文摘 | Garcia D K bengie J A H | 1994 | Aquaulture1994，130，： | 1 |
| 18 | C-reactive protein may be a prognostic factor for the whole gastroenteropancreatic neuroendocrine tumor group显示文摘BACKGROUND Long non-coding RNAs(lncRNAs) are a kind of single-stranded RNA of more than 200 nucleotides in length and have no protein-coding function. Amounting studies have indicated that lncRNAs could play a vital role in the initiation and development of cancers, including gastric cancer(GC). Considering the crucial functions of lncRNAs, the identification and exploration of novel lncRNAs in GC is necessary.AIM To identify independent prognostic markers for the whole gastroenteropancreatic neuroendocrine tumor(GEP-NET) group.METHODS Ninety-three patients diagnosed with GEP-NETs within a specified period were included in this study. Patient data were retrospectively analyzed. The relationships between all independent variables and 5-year survival status calculated during the follow-up period(months) were assessed. In addition, the relationships between the independent variables were investigated.RESULTS When 5-year survival rate was compared, a statistically significant relationship between the age at diagnosis, male gender, tumor size, tumor stage, liver and/or distant metastasis, and tumor grade determined by the Ki-67 level and mitotic count, and the level of C-reactive protein(CRP), was observed. The meansurvival(overall survival) of the study group was 102.5 ± 6.3(SD) mo. The percentages of 1, 3 and 5-year survival were 90%, 72%, and 61%, respectively. In63 of 93 patients, Ki-67 and the mitotic count determined the same grade. The Ki-67 levels in 29 patients and the mitotic count in only 1 patient were in the higher grade. The risk of death increased by 4% for every 1 year increase at the diagnosis age and was 2.0-fold higher for male patients, 3.0-fold higher for G3 according to the mitotic count, 3.7-fold higher for G3 according to the Ki-67 level, 12.7-fold higher for cases with tumor stage 3 or 4 by a 1 cm increase in the ratio of 9% in tumor size, and 6.1-fold higher for patients with liver metastasis for every 1 mg/dL increase in the ratio of 1.5% in CRP level. There was a significant difference between pancreatic and stomach NETs in favor of stomach tumors in terms of survival.CONCLUSION Tumor site, stage, grade and Ki-67 level affected patient survival, and it was observed that CRP affected disease progression(particularly if it was > 20 mg/dL). However, a relationship between surgical resection of the lesion and survival was not shown. Larger scale prospective studies are required to determine whether CRP level may be a poor prognostic factor for the entire GEPNET group. | ?mer Koma? G?ksel Bengi ?zgül Sa?ol Mesut Akarsu | 2019 | World Journal of Gastrointestinal Oncology2019，11，2： | 1 |
| 19 | The role of wildlife in emerging and reemerging zoonoses显示文摘 | Bengis R G Leighton F A Fischer R et a1 | 2004 | Rev Sci Tech2004，23，2： | 1 |
| 20 | Rapid canine distalization using distraction of the periodontal ligament : A preliminary clinical validation of the original technique 显示文摘 | Sayy'n S Bengi AO Gurton AU | 2004 | Angle Orthod2004，74，1： | 1 |
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