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| 1 | Overlap of reflux and eosinophilic esophagitis in two patients requiring different therapies:A review of the literature显示文摘Eosinophilic esophagitis (EE) and gastroesophageal reflux disease (GERD) have overlapping clinical, manometric, endoscopic and histopathologic features. The diagnosis of EE is nowadays based upon the presence of 15 or more eosinophils per high power field (eo/HPF) in esophageal biopsies. We report the cases of two young males suffering from dysphagia and recurrent food impaction with reflux esophagitis and more than 20 eo/HPF in upper-mid esophagus biopsies, both of which became asymptomatic on proton pump inhibitor (PPI) therapy. The first patient also achieved a histologic response, while EE remained in the other patient after effective PPI treatment, as shown by 24-h esophageal pH monitoring. Topical steroid therapy combined with PPI led to complete remission in this latter patient. GERD and EE may be undistinguishable, even by histology, so diagnosis of EE should only be established after a careful correlation of clinical, endoscopic and pathologic data obtained under vigorous acid suppression. These diagnostic difficulties are maximal when both diseases overlap. Limited data are available about this topic, and the interaction between EE and GERD is a matter of debate. In this setting, upper-mid esophagus step biopsies and esophageal pH monitoring of patients on PPI therapy are pivotal to evaluate the role of each disease. A PPI trial is mandatory in patients with a histopathologic diagnosis of EE; in those unresponsive to PPI treatment, EE should be suggested. However, a clinical response to PPI may not rule out quiescent EE, as shown in this report. | Javier Molina-Infante Lucía Ferrando-Lamana Jose María Mateos-Rodríguez Belén Pérez-Gallardo Ana Beatriz Prieto-Bermejo | 2008 | World Journal of Gastroenterology2008，14，9： | 2 |
| 2 | Production and release of yessotoxins by the dinoflagellates Protoceratium reticulatum and Lingulodinium polyedrum in culture显示文摘 | Beatriz P Pilar Riobo'a M Luisa Ferna'ndezb | 2004 | Toxicon2004，44，： | 1 |
| 3 | Marking of otoliths, age validation and growth of Argyrosomus regiu-sjuveniles (Sciaenidae) 显示文摘 | Beatriz M Nin Amalia G S Pérez M ea al | 2010 | Fish Res2010，106，： | 1 |
| 4 | Imaging local estrogen production in single living cells with recombinant fluorescent indicators 显示文摘 | FERNANDO P BEATRIZ D JOSE M P | 2011 | Biosensors & Bioelectronics2011，26，5： | 1 |
| 5 | Flavonol robinobiosides and turinosides from Alternanthera brasiliana(Amaranthaceae) and their effects on lymphocyte proliferation in vitro显示文摘 | Claudia De O Brochado Ana P De Almeida Beatriz P Barreto | 2003 | Journal of the Brazilian Chemical Society2003，14，3： | 1 |
| 6 | Impact of fermentation conditions and refrigerated storage on microbial quality and biogenic amine content of sauerkraut显示文摘 | Elena P Juana F Beatriz S | 2010 | Food Chemistry2010，123，4： | 1 |
| 7 | Low-ealcium dialysate stimulates parathormone secretion and its Long-termuse worsens secondary hyperparathy roidism显示文摘 | Elvira Femandez Merce Borras Beatriz P | | 0，，01： | 1 |
| 8 | Evaluation of the QuEChERS sample preparation approach for the analysis of pesticide residues in olives显示文摘 | CUNHA S C LEHOTAY S J MASTOVSKA K FERNANDES J O BEATRIZ M OLIVEIRA P P | 2007 | J Sep Sci2007，30，4： | 1 |
| 9 | 查看详情显示文摘 | Sanchez C Beatriz J Philippe B Michael P | | 0，，： | 1 |
| 10 | Competitive policies for commercial sea ports in the EUA显示文摘 | Carlos P L Beatriz B | 2004 | Marine Policy2004，，28： | 1 |
| 11 | Use of the European Heart FailureSelf-care Behaviour Scale(EHFScBS) in a Heart Failure Unit in Spain显示文摘 | Beatriz G Josep L Teresa P | | 0，，02： | 1 |
| 12 | Rejection after conversion to a proliferation signal inhibitor in chronic heart transplantation显示文摘 | Francisco González‐Vílchez José A. Vázquez de Prada María J. Paniagua Luis Almenar Sonia Mirabet Manuel Gómez‐Bueno Beatriz Díaz‐Molina Jose M. Arizón Juan Delgado Félix Pérez‐Villa María G. Crespo‐Leiro Luis Martínez‐Dolz Eulalia Roig Javier Segovia José | 2013 | Clin Transplant2013，，6： | 1 |
| 13 | Attachment,depression, and fear of death in older adults: The roles of neediness and perceived availa- bility of social support显示文摘 | BESSER A BEATRIZ P | 2008 | Personality and individual differences2008，44，8： | 1 |
| 14 | Use of the European Heart Failure Self- care Behaviour Scale (EHFScBS) in a heart failure unit in Spain 显示文摘 | Beatriz G Josep L Teresa P | 2006 | Rev Esp Cardiol2006，59，2： | 1 |
| 15 | Ethanol production from non starch carbohydrates of wheat bran 显示文摘 | BEATRIZ P A PAVLA C B GALBE M | 2005 | Bioresource Technology2005，96，7： | 1 |
| 16 | Use of the European Heart Failure Self- care Behaviour Scale (EHFScBS) in a Heart Failure Unit in Spain 显示文摘 | Beatriz G Josep L Teresa P | 2006 | Rev Esp Cardiol2006，59，2： | 1 |
| 17 | Flavonol robinobiosides and turinosides from Alternanthera brasiliana(Amaranthaceae)and their effects on lymphocyte proliferation in vitro显示文摘 | Claudia De O Brochado Ana P De Almeida Beatriz P Barreto | 2003 | Journal of the Brazilian Chemical Society2003，14，3： | 1 |
| 18 | Catalyst screening for oxidative desulfurization using hydrogen peroxide显示文摘 | Beatriz Z Francisco P Miguel A V | 2005 | Catalysis Today2005，106，14： | 1 |
| 19 | Low-calcium dialysate stimulates parathormone secretion and its long-termuse worsens secondary hyperparathyroidism显示文摘 | Elvira Femandez Merce Borras Beatriz P | 1995 | Am Soc Nephrol1995，6，1： | 1 |
| 20 | Trypanosoma cruzi : Molecular characterization of an RNA binding protein differentially expressed in the parasite life cycle显示文摘 | Leticia Pérez-Díaz María Ana Duhagon Pablo Smircich José Sotelo-Silveira Carlos Robello Marco Aurelio Krieger Samuel Goldenberg Noreen Williams Bruno Dallagiovanna Beatriz Garat | 2007 | Experimental Parasitology2007，，： | 1 |
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