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| 1 | 5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells显示文摘以前,导出髓的干细胞(MSC ) 与不确定的脱氧核糖核酸甲基转移酶禁止者 5-azacytidine 对待的老鼠骨头被报导区分 intocardiomyocytes。现在的学习的目的是在从健康骨髓施主获得的人的单音的原子房间调查类似的区别策略的效率。After1-3 段落,文化为 24 h 暴露于到 6 星期进一步的文化跟随的 5-azacytidine (3 mciroM ) 。药处理没导致 myogenic 标记 MyoD 或心脏的 markersNkx2.5 和 GATA-4 的表示并且没在后续期间产出跳动的房间。在补丁夹钳实验,近似 10-15% 对待,未经治疗的房间展出了 L 类型 Ca (2+) 水流。几乎所有房间表面地出现了修正快速或慢的激活动力学的 K (+) 水流。在与匹配时间的控制相比在 6 星期处理以后加倍的 +60 mV 意味着当前的振幅。对待的房间的 Membranecapacitance 比在在处理以后的 controls2 星期内显著地大并且在 6 个星期以后仍然保持高。为 K (+) 隧道 Kv1.1, Kv1.5, Kv2.1, Kv4.3 和 KCNMA1 并且为 Ca (2+) 隧道 Ca (v) 的 mRNAs 的表示层次 1.2 没被 5-azacytidine 影响。在以前显示出禁止 hMSC 的快速或慢慢地激活的 K (+) 水流的集中的 Treatmentwith 钾隧道块 ers tetraethylammonium 和 clofilium 禁止了这些房间的增长。我们的结果建议尽管有进 cardiomyocytes 的 hMSC 的区别的缺席,有 5-azacytidine 的处理在当前的密度引起了深刻变化。 | Bartosz Balanal Cecilia Nicoletti Ihor Zahanich Eva M Graf Torsten Christ Sabine Boxberger Ursula Ravens | 2006 | Cell Research2006，16，12： | 20 |
| 2 | Glutamate transporters in brain ischemia: to modulate or not?显示文摘在这评论,我们简短描述 glutamate (Glu ) 在中央神经系统(CNS ) 的新陈代谢和它的特定的运输和受体。此后,我们集中于有刺激性的氨基酸 transporters, cystine/glutamate antiporters (系统 x c -) 和小囊的 glutamate transporters,明确地在 CNS 和位于 Glu transporters 的规定下面的分子的机制探讨他们的地点和角色。我们响应组织缺氧或局部缺血在 Glu transporter 表示有关改变从在 vitro 或在 vivo 研究提供证据,包括支持在击病人的 Glu transporters 的角色的有限人的数据。而且,通过表示的调整或 Glu transporters 的活动导致大脑忍耐到局部缺血的潜力也被讨论。最后我们包含 ischemic preconditioning 和药理学代理人的申请的现在的策略,例如 β酮抗菌素, amitriptyline, riluzole 和 N-acetylcysteine,它对局部缺血导致紧张的纸巾的重要保护。 | Weronika KRZYZANOWSKA Bartosz POMIERNY Magorzata FILIP Joanna PERA | 2014 | Acta Pharmacologica Sinica2014，，4： | 17 |
| 3 | 分布式发电的高覆盖率对电力系统设计和运行的影响分析(英文)显示文摘文章探讨了电力公用事业大规模实施分布式发电的问题。分布式发电的日益普及将对电力系统的设计、工程实施以及运行的可靠性提出很高的要求。作者考察了分布能源(DER)的大规模应用对电力系统设计、安全运行与绩效的影响,并引用电力示范项目例举说明。同时,论文也展望了未来的电力公用事业发展远景,描述了应用于电力公用事业的分布式发电技术。 | Bartosz Wojszczyk Omar Al-Juburi 王靖 | 2009 | 电网技术2009，33，15： | 16 |
| 4 | Is cardiac resynchronisation therapy feasible, safe and beneficial in the very elderly?显示文摘ObjectiveTo evaluate 心脏的同一时刻治疗(CRT ) 培植是否与经历 CRT 培植的 symptoms.MethodsConsecutive 病人一起在 octogenarians 和协会可行、安全,从二个英国中心被招募。根据年龄组织的病人:<80 &≥80 年。基线人口分布,复杂并发症和结果在 439 个病人的那些 groups.ResultsA 总数之间被比较在这研究, 26%≥ 是谁被包括;80 年。Octogenarians 更经常与心脏的同一时刻治疗使用高压脉冲来消减心脏相比收到了心脏的再同步治疗心律调整器。从心律调整器的升级在两个组是普通的(16%<80 年对 22%≥80 年, P = NS ) 。合作病态在两个组是同样普通的(全面糖尿病:25% , atrial 纤维性颤动:23% ,高血压:45%) 。更耐心的年龄 ≥80 年有重要的长期的肾疾病(CKD,估计的 glomerular 过滤率 <45 mL/min 每 1.73 m 2,44% 对 22% , P <0.01 ) 。全面复杂并发症率(任何东西) 在两个组是类似的(16% 对 17% , P = NS ) 。两个组表明了征兆的利益。一个年死亡率作为与更年轻的队相比是在 octogenarians 更大的几乎四褶层(13.9% 对 3.7% , P <0.01 ).ConclusionsCRT 看起来安全在尽管有广泛的合作病态老、特别地经常严重 CKD。征兆的改进看起来有意义。增加的策略是 CRT 的潜在的候选人的有 CHF 的老病人的适当鉴定被要求。 | Bartosz Olechowski Rebecca Sands Donah Zachariah Neil P Andrews Richard Balasubramaniam Mark Sopher John Paisey Paul R Kalra | 2015 | Journal of Geriatric Cardiology2015，12，5： | 5 |
| 5 | Factors associated with irritable bowel syndrome symptoms in hemodialysis patients显示文摘AIM: To investigate clinical characteristics associated with the presence of irritable bowel syndrome (IBS) symptoms in hemodialysis (HD) patients.METHODS: This was a cross-sectional study. A questionnaire based on the Bowel Disease Questionnaire that records gastrointestinal symptoms was given to 294 patients in 4 dialysis centers. A total of 196 (67%) subjects returned the survey. A multivariable logistic regression model was used to identify factors significantly associated with IBS symptoms. RESULTS: Symptoms compatible with IBS were present in 27 (13.8%) subjects and independently associated with low post-dialysis serum potassium [OR = 0.258, 95% CI (0.075-0.891), P = 0.032], paracetamol use [OR = 3.159, 95% CI (1.214-8.220), P = 0.018], and Kidney Disease Quality of Life (KDQOL) cognitive function score [OR = 0.977, 95% CI (0.956-0.999), P = 0.042]. Univariate regressions were also performed and the reported significance is for multivariate analysis. No association was detected for age, gender, depressed mood, smoking (present or past), body mass index, albumin level, Kt/V, sodium preor post-dialysis level, change in potassium level during HD, proton pump inhibitor or H2 blocker use, aspirin use, residual diuresis, hepatitis B or C infection, diabetes mellitus, marital status and education level. CONCLUSION: This study examined potential risk factors for symptoms compatible with IBS in HD patients and identified an association with paracetamol use, post-dialysis potassium level and KDQOL-cognitive function score. | Bartosz Fiderkiewicz Alicja Rydzewska-Rosoowska Micha Myliwiec Magdalena Birecka Bozenna Kaczanowska Grazyna Rydzewska Andrzej Rydzewski | 2011 | World Journal of Gastroenterology2011，17，15： | 5 |
| 6 | Correlations between skin lesions induced by anti-tumor necrosis factor-α and selected cytokines in Crohn's disease patients显示文摘AIM:To investigate the correlation between the appearance of skin lesions and concentration of interleukin(IL)-17A,IL-23 and interferon-γ(IFN-γ)in Crohn’s disease(CD)patients during anti-tumor necrosis factor-α(TNF-α)therapy METHODS:A prospective study included 30 adult patients with CD of Caucasian origin(19 men and 11women;mean age±SD 32.0±8.6 years)during biological therapy with anti-TNF-αantibodies from January2012 to March 2013.Eighteen patients were treated with infliximab,seven with adalimumab and five withcertolizumab.Inclusion criteria were exacerbation of the underlying disease,Crohn’s Disease Activity Index over 300 and the ineffectiveness of previously used non-biological therapies.Patients with a history of psoriasis,atopic dermatitis and other autoimmune skin lesions were excluded from the study.The control group consisted of 12 healthy subjects.A diagnostic survey was carried out,blood tests and careful skin examination were performed,and the serum levels of IL-17,IL-23 and IFN-γwere measured using an enzyme-linked immunosorbent assays technique.Dermatoses that have developed in the course of biological therapy in patients who had no pre-existing skin lesions of similar character were qualified as skin lesions induced by antiTNF-αtherapy.RESULTS:Skin manifestations occurred in 18 of CD patients during the anti-TNF-αtherapy(60%),in the average time of 10.16±3.42 mo following the beginning of the 52-wk treatment cycle.Skin lesions observed in CD patients during biological therapy included psoriasiform lesions(44.4%),and eczema forms lesions(22.2%).In CD patients with drug induced skin lesions significantly higher levels of hemoglobin(13.3±1.5 g/dL vs 10.8±1.9 g/dL,P=0.018)and hematocrit(39.9%±4.5%vs 34.3%±5.4%,P=0.01),as well as a significantly lower level of platelets(268±62×103/μL vs 408±239×103/μL,P=0.046)was observed compared with CD patients without skin manifestations.The concentrations of IL-17A and IL-23in CD patients with skin lesions developed under antiTNF-αtherapy were significantly higher compared to those in patients without lesions(IL-17A:39.01±7.03pg/mL vs 25.71±4.90 pg/mL,P=0.00004;IL-23:408.78±94.13 pg/mL vs 312.15±76.24 pg/mL,P=0.00556).CONCLUSION:Skin lesions in CD patients during bio-logical therapy may result from significantly increased concentrations of IL-17A and IL-23,which are strongly associated with TNF-α/Th1 immune pathways. | Marcin Wodarczyk Aleksandra Sobolewska Bartosz Wójcik Karolina Loga Jakub Fichna Maria Wisniewska-Jarosińska | 2014 | World Journal of Gastroenterology2014，20，22： | 2 |
| 7 | Off-clamp Robot-assisted Partial Nephrectomy Preserves Renal Function: A Multi-institutional Propensity Score Analysis显示文摘 | Bartosz F. Kaczmarek Youssef S. Tanagho Shahab P. Hillyer Jeffrey K. Mullins Mireya Diaz Quoc-Dien Trinh Sam B. Bhayani Mohamad E. Allaf Michael D. Stifelman Jihad H. Kaouk Craig G. Rogers | 2012 | European Urology2012，，： | 2 |
| 8 | Effect of CD14/TLR4 antagonist on GnRH/LH secretion in ewe during central inflammation induced by intracerebroventricular administration of LPS显示文摘Background: Immune stress induced by lipopolysaccharide(LPS) influences the gonadotropin-releasing hormone(GnRH)/luteinizing hormone(LH) secretion. Presence of LPS interacting Toll-like receptor(TLR) 4 in the hypothalamus may enable the direct action of LPS on the GnRH/LH secretion. So, the aim of the study was to investigate the influence of intracerebroventricular(icv) injection of TLR4 antagonist on GnRH/LH secretion in anestrous ewes during LPS-induced central inflammation. Animals were divided into three groups icv-treated with: Ringer-Locke solution, LPS and TLR4 antagonist followed by LPS.Results: It was demonstrated that TLR4 antagonist reduced LPS-dependent suppression of GnRH gene expression in the preoptic area and in the medial basal hypothalamus, and suppression of receptor for GnRH gene expression in the anterior pituitary gland. It was also shown that TLR4 antagonist reduced suppression of LH release caused by icv injection of LPS. Central administration of LPS stimulated TLR4 gene expression in the medial basal hypothalamus.Conclusions: It was indicated that blockade of TLR4 prevents the inhibitory effect of centrally acting LPS on the GnRH/LH secretion. This suggests that some negative effects of bacterial infection on the hypothalamic-pituitary-gonadal axis activity at the hypothalamic level may be caused by central action of LPS acting through TLR4. | Karolina Haziak Andrzej Przemyslaw Herman Karolina Wojtulewicz Bartosz Pawlina Kamila Paczesna Joanna Bochenek Dorota Tomaszewska-Zaremba | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 2 |
| 9 | Oxidative stress plants显示文摘 | Bartosz G | 1977 | Acta Physiol Plant1977，19，： | 1 |
| 10 | 显示文摘 | Abraham F J Bartosz T Ali J H | 2006 | Journal of Organometallic Chemistry2006，691，22： | 1 |
| 11 | Dynamics of the arch-type reconfigurable machine tool显示文摘 | Jaspreet Dhupia Bartosz Powalka Reuven Katz A. Galip Ulsoy | 2006 | International Journal of Machine Tools and Manufacture2006，，2： | 1 |
| 12 | Reactive oxygen species:Destroyers or messengers?显示文摘 | Bartosz G | 2009 | Biechem Pharmacol2009，77，8： | 1 |
| 13 | Volume-and size-related lead-lag effects in stock returns and volatility:An empirical investigation of the Warsaw Stock Exchange显示文摘 | Bartosz Gebka | 2006 | International Review of Financial Analysis2006，11，： | 1 |
| 14 | Genetic Polymorphisms and the Risk of Myocardial Infarction in Patients Under 45 Years of Age显示文摘 | Agata Sakowicz Wojciech Fendler Malgorzata Lelonek Bartosz Sakowicz Tadeusz Pietrucha | 2013 | Biochemical Genetics2013，，： | 1 |
| 15 | 2,7-dichlorofluorescin oxidation and reactive oxygen species: what does it measure 显示文摘 | JAKUBOWSKI W BARTOSZ G | 2000 | Cell Biol Int2000，24，10： | 1 |
| 16 | Clustering-based en- sembles for one-class classification 显示文摘 | BARTOSZ K MICHAL W BOGUSLAW C | 2014 | Information Sciences2014，，： | 1 |
| 17 | The pea mitochondrial atp6: RNA editing and similarity of presequences in the Vicieae tribe显示文摘 | Marta Gibala Bartosz Szczesny Jan Kieleczawa Hanna Janska | 2004 | Current Genetics2004，，4： | 1 |
| 18 | High Serum Procalcitonin Concentration in Kawasaki Disease 显示文摘 | Bartosz K Agnieszka M J Andrzej P | 1998 | Med Sci Monit1998，4，6： | 1 |
| 19 | Antioxidative and prooxidative effects of quercetin on A549 cells显示文摘 | ROBASZKIEWICZ A BALCERCZYK A BARTOSZ G | 2007 | Cell Biol Int2007，31，10： | 1 |
| 20 | Impact of SOX18 expression in cancer cells and vessels on the outcome of invasive ductal breast carcinoma显示文摘 | Bartosz Pula Mateusz Olbromski Andrzej Wojnar Agnieszka Gomulkiewicz Wojciech Witkiewicz Maciej Ugorski Piotr Dziegiel Marzena Podhorska-Okolow | 2013 | Cellular Oncology2013，，6： | 1 |
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