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491篇 您的检索式:作者名="BARBOSA R"
    题名 作者 年代 出处 被引量
1Value of a newly sequenced bacterial genome显示文摘Next-generation sequencing(NGS) technologies have made high-throughput sequencing available to medium- and small-size laboratories, culminating in a tidal wave of genomic information. The quantity of sequenced bacterial genomes has not only brought excitement to the field of genomics but also heightened expectations that NGS would boost antibacterial discovery and vaccine development. Although many possible drug and vaccine targets have been discovered, the success rate of genome-based analysis has remained below expectations. Furthermore, NGS has had consequences for genome quality, resulting in an exponential increase in draft(partial data) genome deposits in public databases. If no further interests are expressed for a particular bacterial genome, it is more likely that the sequencing of its genome will be limited to a draft stage, and the painstaking tasks of completing the sequencing of its genome and annotation will not be undertaken. It is important to know what is lost when we settle for a draft genome and to determine the 'scientific value' of a newly sequenced genome. This review addresses the expected impact of newly sequenced genomes on antibacterial discovery and vaccinology. Also, it discusses the factors that could be leading to the increase in the number of draft deposits and the consequent loss of relevant biological information.Eudes GV Barbosa Flavia F Aburjaile Rommel TJ Ramos Adriana R Carneiro Yves Le Loir Jan Baumbach Anderson Miyoshi Artur Silva Vasco Azevedo 2014World Journal of Biological Chemistry2014,5,2:7
2Mechanical behavior and microstructure of high carbon Si- Mn- Cr steel with TRIP effect 显示文摘SANTOS D B BARBOSA R De OLIVEIRA P P 2009ISH International2009,49,10:1
3Prevalance of anemia and its association with cardio-renal syndrome显示文摘Silva R P Barbosa P H Kimura O S 0,,02:1
4Characterization of a cloned cDNA encoding rabbit myelin P2 protein显示文摘 Barbosa E Reed R 1995J Biol Chem1995,263,:1
5Effect of carotenoid source and dietary lipid content on blood astaxanthin concentration in rainbow trout ( Oncorhynehus mykiss) 显示文摘BARBOSA M J MORAl S R CHOUBERT 1999Aquaculture1999,176,34:1
6Extended regiments of the combined contraceptive vaginal ring containing etonogestrel and ethinyl estradiol: effects on lipid metabolism 显示文摘BARREIROS FA FALBO GCA BARBOSA R 2011Contraception2011,84,2:1
7Vohammetric and morphological characterization of copper electrodeposition from non - cyanide electrolyte 显示文摘De Almeida M R H Carlos I A Barbosa L L 2002Journal of Applied Electrochemistry2002,32,:1
8Spray forming high speed steel-properties and processing 显示文摘Mesquita R A Barbosa C A 2004Materials Science and Engineering A2004,383,:1
9Suppresion of chaos in a CO(2) laser by feedback显示文摘LIU Y BARBOSA L C RIOSLEITE J R 1994Phys Lett A1994,193,:1
10A new method to obtain good anatomical slides of heterogeneous plant parts显示文摘BARBOSA A C F PACE M R WITOVISK L 2010IAWA Journal2010,31,4:1
11Electrochemical and surface modifications on N+-ion-implanted 316L stainless steel 显示文摘LEITAO E SILIVA R A BARBOSA M 1997J Mater Sci Mater Med1997,8,:1
12Intravitreal injection versus sub-Tenon's infusion of triamcinolone acetonide for re- fractory diabetic macular edema: a randomized clinical trial 显示文摘Bonini MA Jorge R Barbosa JC 2005Invest Ophthalmol Vis Sci2005,46,:1
13Evaluation and management of mild traumatic brain injury: an eastern as- sociation for the surgery of trauma practice management guideline 显示文摘Barbosa RR Jawa R Watters JM 2012J Trauma Acute Care Surg2012,73,54:1
14Analysis of quinolone residues in edible animal products显示文摘Hemandez-Arteseros JA Barbosa J Compano R 2002J Chromatogr A2002,945,:1
15Complex-order dynamics in hexapod locomotion 显示文摘SILVA M F MACHADO J A BARBOSA R S 2006Signal Processing2006,86,10:1
16Full wave analysis of a nonradiative dielectric waveguide with a pseudochiral-slab显示文摘Topa A L Paiva C R Barbosa A M 1998IEEE Trans Microwave Theory Tech1998,44,9:1
17Metabolic effects of L - alanyl - glutamine in burned rats显示文摘Barbosa C R Guimaraes S B de Vasconcelos P R 2006Burns2006,32,4:1
18Constituintes quimicos de Melaleuca alternifolia (Myrtaceae) 显示文摘VIEIRA T R BARBOSA L C A MALTHA C R A 2004Quimica Nova2004,27,4:1
19Voltage stability probabilistic assessment in composite systems-modeling unsolvability and controllability loss显示文摘Anselmo Barbosa Rodrigues Prada R B Maria Da Guia da Silva 2010IEEE Trans on Power Systems2010,25,3:1
20The hedgehog gene fa- mily in Drosophila and vertebrate development显示文摘Fietz MJ Concordet JP Barbosa R 1994Developme- nt1994,,:1
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