维普中文期刊产品整合服务
56篇 您的检索式:作者名="BAJBOUJ M"
    题名 作者 年代 出处 被引量
1New aspects in the pathomechanism and diagnosis of the laryngopharyngeal reflux-clinical impact of laryngeal proton pumps and pharyngeal p H metry in extraesophageal gastroesophageal reflux disease显示文摘AIM:To determine the laryngeal H+K+-ATPase and pharyngeal p H in patients with laryngopharyngeal reflux(LPR)-symptoms as well as to assess the symptom scores during PPI therapy.METHODS:Endoscopy was performed to exclude neoplasia and to collect biopsies from the posterior cricoid area(immunohistochemistry and PCR analysis).Immunohistochemical staining was performed with monoclonal mouse antibodies against human H+K+-ATPase.Quantitative real-time RT-PCR for each of the H+K+-ATPase subunits was performed.The p H values were assessed in the aerosolized environment of the oropharynx(Dxp H Catheter) and compared to a subsequently applied combined p H/MII measurement.RESULTS:Twenty patients with LPR symptoms were included.In only one patient,the laryngeal H+K+-ATPase was verified by immunohistochemical staining.In another patient,real-time RT-PCR for each H+K+-ATPase subunit was positive.Fourteen out of twenty patients had pathological results in Dxp H,and 6/20 patients had pathological results in p H/MII.Four patients had pathological results in both functional tests.Nine out of twenty patients responded to PPIs.CONCLUSION:The laryngeal H+K+-ATPase can only be sporadically detected in patients with LPR symptoms and is unlikely to cause the LPR symptoms.Alternative hypotheses for the pathomechanism are needed.The role of pharyngeal p H-metry remains unclearand its use can only be recommended for patients in a research study setting.Valentin Becker Romina Drabner Simone Graf Christoph Schlag Simon Nennstiel Anna Maria Buchberger Roland M Schmid Dieter Saur Monther Bajbouj 2015World Journal of Gastroenterology2015,21,3:14
2Clinical trial:persistent gas- troesophageal reflux symptoms despite standard therapy with proton pump inhibitors a follow - up study of intraluminal - impedance guided therapy 显示文摘Becker V Bajbouj M Waller K et at 2007Aliment Pharmacol Ther2007,26,10:1
3Cognitive function over the treatment course of depression in middle-age pailents:correlation with brain Mri signal hyperintensities显示文摘Neu P Bajbouj M Schilling A 2005J psychiatr Res2005,39,2:1
4Cognitive function over the treatment course of depression in middle-aged patients:correlation with brain MRI signal hyperintensities显示文摘Neu P Bajbouj M Schilling A 0,,:1
5Effects of right unilateral electroc-onvulsive therapy on motor cortical excitability in depressive patients 显示文摘Bajbouj M Lang UE Niehaus L 2006J Psychia Res2006,40,4:1
6Argon plasma coagulation of cervical heterotopie gastric mucosa as an alternative treatment for globus sensations显示文摘Bajbouj M Becker V Eckel F 2009Gastroenterology2009,137,2:1
7Clinical trial: persistent gas-tro-oesophageal reflux symptoms despite standard therapy with protonpump inhibitors-a follow-up study of intraluminal-impedance guidedtherapy 显示文摘Becker V Bajbouj M Waller K 2009Aliment PHarmacol Ther2009,26,10:1
8High-dose esomeprazole for treatment of symptomatic refractory gastroesophageal reflux disease-a prospective pH-metry/impedance-controlled study显示文摘Bajbouj M Becker V Phillip V 2009Digestion2009,80,2:1
9Argon plasma co- agulation of cervical hetemtopic gastric mucosa as an alternative treatment for globus sensations显示文摘BAJBOUJ M BECKER V ECKEL F 2009Gastroenterology2009,137,2:1
10Antidepressant electroconvul- sive therapy:mechanism of action,recent advances and limi- tations显示文摘Merkl A Heuser I Bajbouj M 2009Exp Neurol2009,219,1:1
11Combined pH-metry/impedance monitoring increases the diagnostic yield in patients with atypical gastroesophngeal reflux symptoms显示文摘Bajbouj M Becker V Neuber M 2007Digestion2007,76,34:1
12High-dose esomeprazole for treatment of symptomatic refractory gastroesophageal reflux disease-a prospective pH-metry/impedance-controlled study显示文摘Bajbouj M BeckerV Phillip V 0,,02:1
13Argon plasma co- agulation of cervical heterotopic gastric mucosa as an al- ternative treatment for globus sensations 显示文摘Bajbouj M Becker V Eckel F 2009Gastroenter- ology2009,137,2:1
14Cognitive function over the treatment course of depression in middle-aged patients:correlation with brain MRI signal hyperintensities显示文摘Neu P Bajbouj M Schilling A 2005J Psychiatr Res2005,39,2:1
15Lack of P53 augments thymoquinone induced apoptosis and caspase activation in human osteosarcoma cells显示文摘Roepke M Diestel A Bajbouj K 2007Cancer Biol Ther2007,6,2:1
16Maintenance treatment of de- pression in old age显示文摘Bajbouj M Danker-Hopfe H 2006N Engl J Med2006,354,23:1
17Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis显示文摘Bennecke M Kriegl L Bajbouj M Retzlaff K Robine S Jung A 2010Cancer Cell2010,18,2:1
18Association of the G1947A COMT (Va1(108/158) Met) gene polymorphism with prefrontal P300 during informa-tion processing显示文摘Gallinat J Bajbouj M Sander T Schlattmann P Xu K Ferro E F 0,,01:1
19Ink4a/Arf and oncogene-induced se-nescence prevent tumor progression during alternativecolorectal tumorigenesis显示文摘Bennecke M? Kriegl L Bajbouj M Retzlaff K? RobineS? Jung A 2010Cancer Cell2010,18,:1
20Cerebral blood flow during vagus nerve stimulation -a transcranial Doppler study 显示文摘Neu P Heuser I and Bajbouj M 2005Neuropsychobiology2005,51,4:1
返回顶部 每页显示:
共3页 首页 上一页 第1页 下一页 末页 /3 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费