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| 1 | 基于生存分析模型的游客停留天数影响因素分析——以大连滨海旅游为例显示文摘游客的停留天数是影响旅游经济发展的一个重要因素。但是,由于停留天数变量特有的统计属性和复杂性,如数据删失和非负性,使得经济研究领域很少有学者系统地的研究这一问题。本文通过使用计量经济学的参数化生存分析模型分析游客停留天数的决定因素,这对旅游需求研究是一个很好的创新。在研究过程中,为了揭示影响游客停留天数的主要因素,本文考虑了多个关于游客的社会-人口统计特征等变量。结果显示,重复旅行的游客和距离较远的游客会停留较长的天数。因此,未来研究需要进一步分析具有这些特征的游客群体以及他们的经济状况和旅游活动特征等情况。游客的收入水平和年龄也对停留天数具有显著的影响。此外,游客受教育程度越高,停留天数越少。最后,本文分别分析了这些结果对旅游管理决策的含义。 | 王尔大 李花 Bertis B.Little | 2014 | 运筹与管理2014，23，1： | 4 |
| 2 | 冰雹对美国玉米带作物产量影响模拟(英文)显示文摘为了尝试计算机模拟方法能否成为制定作物保险保费的辅助性工具,该研究运用计算机模拟模型预测冰雹对作物产量的影响。通过对现有EPIC(综合气候因素的环境政策)模型增加冰雹天气模块,即冰雹事件发生概率的数学模型,模拟冰雹对作物产量的影响。除此之外,该研究还模拟了干旱和霜冻等天气因素对美国Iowa,Illinoi和Indiana等3个玉米带州作物产量的影响。首先介绍数据来源及处理方法,讨论建立冰雹模拟模型过程以及对模型进行有效性检验;然后运用统计分析方法对模型模拟结果与实际观察结果进行比较,检验模型模拟结果的准确性。结果表明EPIC模型可以达到95%甚至更高的产量预测的准确性;同时,冰雹灾害模拟结果也可以达到一个较为合理的准确性(R2>0.7)。这些结果表明本研究所建立的增加冰雹模块的EPIC模型可以作为一个较为可靠的冰雹引起的作物产量损失的预测方法.该模型可以用来模拟冰雹事件发生的概率以及其对各种作物产量造成的损失。 | 王尔大 Bertis B.Little Jimmy R.Williams 于洋 | 2012 | 农业工程学报2012，28，21： | 2 |
| 3 | Cattle behaviour classification from collar, halter, and ear tag sensors显示文摘In this paper,we summarise the outcome of a set of experiments aimed at classifying cattle behaviour based on sensor data.Each animal carried sensors generating time series accelerometer data placed on a collar on the neck at the back of the head,on a halter positioned at the side of the head behind the mouth,or on the ear using a tag.The purpose of the study was to determine how sensor data from different placement can classify a range of typical cattle behaviours.Data were collected and animal behaviours(grazing,standing or ruminating)were observed over a common time frame.Statistical features were computed from the sensor data and machine learning algorithms were trained to classify each behaviour.Classification accuracies were computed on separate independent test sets.The analysis based on behaviour classification experiments revealed that different sensor placement can achieve good classification accuracy if the feature space(representing motion patterns)between the training and test animal is similar.The paper will discuss these analyses in detail and can act as a guide for future studies. | A.Rahman D.V.Smith B.Little A.B.Ingham P.L.Greenwood G.J.Bishop-Hurley | 2018 | Information Processing in Agriculture2018，5，1： | 2 |
| 4 | Secular change in the growth status of urban and rural school children aged 6-13 years in Oaxaca,southern Mexico显示文摘 | Robert m.malina Maria eugenia pen~ a reyes Bertis b.little | | 0，，： | 1 |
| 5 | Multiphasic scaffolds for the repair of osteochondral defects:Outcomes of preclinical studies显示文摘Osteochondral defects are caused by injury to both the articular cartilage and subchondral bone within skeletal joints. They can lead to irreversible joint damage and increase the risk of progression to osteoarthritis. Current treatments for osteochondral injuries are not curative and only target symptoms, highlighting the need for a tissue engineering solution. Scaffold-based approaches can be used to assist osteochondral tissue regeneration, where biomaterials tailored to the properties of cartilage and bone are used to restore the defect and minimise the risk of further joint degeneration. This review captures original research studies published since 2015, on multiphasic scaffolds used to treat osteochondral defects in animal models. These studies used an extensive range of biomaterials for scaffold fabrication, consisting mainly of natural and synthetic polymers. Different methods were used to create multiphasic scaffold designs, including by integrating or fabricating multiple layers, creating gradients, or through the addition of factors such as minerals, growth factors, and cells. The studies used a variety of animals to model osteochondral defects, where rabbits were the most commonly chosen and the vast majority of studies reported small rather than large animal models. The few available clinical studies reporting cell-free scaffolds have shown promising early-stage results in osteochondral repair, but long-term follow-up is necessary to demonstrate consistency in defect restoration. Overall, preclinical studies of multiphasic scaffolds show favourable results in simultaneously regenerating cartilage and bone in animal models of osteochondral defects, suggesting that biomaterials-based tissue engineering strategies may be a promising solution. | Rouyan Chen Jasmine Sarah Pye Jiarong Li Christopher B.Little Jiao Jiao Li | 2023 | Bioactive Materials2023，，9： | 1 |
| 6 | Treatment options for paraphimosis显示文摘 | B.Little M.White | 2005 | International Journal of Clinical Practice2005，，5： | 1 |
| 7 | 《小家伙们》显示文摘凯迪克大奖获奖作家、插画家维拉·布罗斯哥的新书《小家伙们》,讲述了一群戴橡子帽、生活在小岛上的神秘小家伙们的故事.它们小而强壮,聪明且无畏.利用人数和紧密的团队合作,他们跋山涉水,穿过黑暗的森林,爬上高大的树木,举起沉重的原木,挖深洞穴,甚至在一只大棕熊的肚子上蹦跳.他们这么做是为了给他们的小家伙们找点吃的. | Billie B.Little 陈佳 | 2019 | 中学生英语2019，0，35： | 0 |
| 8 | 《岛屿之城》显示文摘卡莉·华莱士的《岛屿之城〉将读者带到了一个古代岩石城市的世界,在那里,居住在海洋的造物主们曾经利用魔法控制着大地和岩石、天空和海洋。华莱士用幻想的生物和神秘的咒语歌编织出了一个不会令你失望的复杂故事. | Billie B.Little 笪景行(译) | 2019 | 中学生英语2019，0，3： | 0 |
| 9 | MDMX phosphorylation-dependent p53 downregulation contributes to an immunosuppressive tumor microenvironment显示文摘A role of tumor-suppressive activity of p53 in the tumor microenvironment(TME)has been implicated but remains fairly understudied.To address this knowledge gap,we leveraged our MdmxS314A mice as recipients to investigate how implanted tumor cells incapacitate host p53 creating a conducive TME for tumor progression.We found that tumor cell-associated stress induced p53 downregulation in peritumor cells via an MDMX-Ser314 phosphorylation-dependent manner.As a result,an immunosuppressive TME was developed,as reflected by diminished immune cell infiltration into tumors and compromised macrophage M1 polarization.Remarkably,ablation of MDMX-Ser314 phosphorylation attenuated p53 decline in peritumor cells,which was associated with mitigation of immunosuppression and significant tumor growth delay.Our data collectively uncover a novel role of p53 in regulating the tumor immune microenvironment,suggesting that p53 restoration in the TME can be exploited as a potential strategy of anticancer therapy. | Bing Wang Chuan-Bian Lim Jiawei Yan Lizhen Li Jufang Wang John B.Little Zhi-Min Yuan | 2020 | Journal of Molecular Cell Biology2020，12，9： | 0 |
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