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| 1 | 二甲双胍长期治疗2型糖尿病患者以及维生素B12缺乏的危险性:随机安慰剂对照研究(摘要)显示文摘目的 研究接受胰岛素治疗的2型糖尿病患者中,二甲双胍所致维生素B12缺乏(〈150pmol/L)、低浓度维生素B12(150—220pmol/L)的发生率,以及叶酸和同型半胱氨酸的浓度。 | Jolien de Jager Adriaan Kooy Philippe Lehert Michiel G Wulffele Jan van der Kolk Daniel Bets Joop Verburg Ab J M Donker Coen D A Stehouwer 许翎岭(译) | 2010 | 英国医学杂志中文版2010，13，5： | 2 |
| 2 | Interferon-γ inhibits ghrelin expression and secretion via a somatostatin-mediated mechanism显示文摘AIM:To investigate if and how the proinflammatory cytokine interferon γ(IFNγ) affects ghrelin expression in mice.METHODS:The plasma concentration of ghrelin,andgastric ghrelin and somatostatin expression,were examined in wild-type mice and mice infected with Helicobacter pylori(H.pylori).Furthermore,ghrelin expression was examined in two achlorhydric mouse models with varying degrees of gastritis due to bacterial overgrowth.To study the effect of IFNγ alone,mice were given a subcutaneous infusion of IFNγ for 7 d.Finally,the influence of IFNγ and somatostatin on the ghrelin promoter was characterized.RESULTS:H.pylori infection was associated with a 50% reduction in ghrelin expression and plasma concentration.Suppression of ghrelin expression was inversely correlated with gastric inflammation in achlorhdyric mouse models.Subcutaneous infusion of IFNγ suppressed fundic ghrelin mRNA expression and plasma ghrelin concentrations.Finally,we showed that the ghrelin promoter operates under the control of somatostatin but not under that of IFNγ.CONCLUSION:Gastric infection and inflammation is associated with increased IFNγ expression and reduced ghrelin expression.IFNγ does not directly control ghrelin expression but inhibits it indirectly via somatostatin. | Jesper AB Strickertsson Kristina BV DΦssing Anna JM Aabakke Hans-Olof Nilsson Thomas VO Hansen Ulrich Knigge Andreas Kjr Torkel Wadstrm Lennart Friis-Hansen | 2011 | World Journal of Gastroenterology2011，17，26： | 2 |
| 3 | 脊髓损伤后残存自主神经功能载录国际标准显示文摘近年来,脊髓损伤神经学分类园际标准(International Stand- ards for the Neurological Classification of Spinal Cord Injury, ISNCSCI)被用来记载脊髓损伤后运动和感觉功能的损害,目前该标准已是第六版。1992年第一份国际认可的标准出版时,曾进行了较大的修订,修订内容包括完全性损伤与不完全性损伤的定义, | MS Alexander AB Jackson W Donovan DE Graves SL Elliott A Krassioukov AW Sheel I Estoresl B Green A Gousse NL Braekett D Cardenas M Kennelly A-K Karlason F Biering-Sorensen K Krogh T Linsenmeyer R Marino J Ditunno CJ Mathias I Perkash G Creasey G Schilero J Wecht B Schurch V Dietz J Sonksen S Stiens D Bodner LA Wuermser J-J Wyndaele 周谋望 刘楠 S Charlifue | 2010 | 中华物理医学与康复杂志2010，32，4： | 2 |
| 4 | Replicating mesenchymal cells in the condyle and the glenoid fossa during mandibular forward positioning 显示文摘 | Rabie AB Wong L Tsai M | 2003 | Am J Orthod Dentofacial Orthop2003，123，： | 1 |
| 5 | ln vivo recombineering of bacteriophage lambda by PCR fragments and single-strand oligonucleotides显示文摘 | Oppenheim AB Rattray AJ Bubunenko M | 2004 | Virology2004，319，2： | 1 |
| 6 | Correlation of HBV DNA PCR and HBeAg in hepatitis B carriers 显示文摘 | Hussain AB K aramat K A Anwar M | 2004 | J Coil Physicians Surg Pak2004，14，： | 1 |
| 7 | Mac-1 (CD11 b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation显示文摘 | van Spricl AB Lenson JH van Egmond M | 2001 | Blood2001，97，8： | 1 |
| 8 | Phenolic constituents of Rhus semialata leaves显示文摘 | Bagchi A Sahai M Ray AB | 1985 | Planta Medica1985，5，： | 1 |
| 9 | Immunogenicity of glutaradehyde-tanned bovine pericardium显示文摘 | Dahm M Lyman WD Schwell AB | 1990 | J Thorac Cardivasc Surg1990，90，3： | 1 |
| 10 | A genome-wide search for schizophrenia susceptibility genes显示文摘 | Shaw SH Kelly M Smith AB | 1998 | Am J Med Genet1998，81，5： | 1 |
| 11 | What is the best perfusion temperature for coronary revascularization显示文摘 | EngelmanR M Pleet AB RousouJA | 1996 | J Thorac Cardiovasc Surg1996，112，6： | 1 |
| 12 | Response surface methodological study on lipase-catalyzed synthesis of amino acid surfactants显示文摘 | Soo EL Salleh AB Basri M | 2004 | Process Biochemistry2004，39，： | 1 |
| 13 | Effects of p21 (Cipl/Wafl) at both the G1/S and the G2/M cell cycle transitions:pRb is a critical determinant in blocking DNA replication and in preventing' endoreduplication 显示文摘 | Niculescu AB Chen X Smeets M | 1998 | Mol Cell Biol1998，18，1： | 1 |
| 14 | Risk of symptomatic central nervous system (CNS) progression and secondary hemorrhage in patients with non-squamous non-small cell lung cancer (NSCLC) receiving bevacizumab ( BV ) -based first-line therapy 显示文摘 | Archer V Reck M Sandier AB | 2008 | J Clin Oncol2008，26，： | 1 |
| 15 | Reporting results ofcancer treatment显示文摘 | Miller AB Hoogstraten B Staquet M | 1981 | Cancer1981，47，1： | 1 |
| 16 | Polymorphism of the IL-4 ,TNF-a|pha, and Fcepsi|on RIbeta genes and the risk of allergic disorders in at-risk infants显示文摘 | Zhu S Chan Yeung M Becker AB | 2000 | Am J Respir Crit Care Med2000，161，5： | 1 |
| 17 | Predictors of toler- ance to chemotherapy in older cancer patients: a prospective pilot study显示文摘 | Externmnn M CH Cantor AB Corcoran MB | 2002 | Eur J Cancer2002，38，： | 1 |
| 18 | Heavy chain deposition disease:recurrence in a renal transplant and report of IgG (2) subtype显示文摘 | Herzenberg AM Kiaii M Magil AB | | 0，，05： | 1 |
| 19 | Chapter 5 : Up- dating the natural history of HPV and anogenital cancer 显示文摘 | Moscicki AB Schiffman M Kjaer S | 2006 | Vaccine2006，24，3： | 1 |
| 20 | Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration显示文摘 | el-Remessy AB Bartoli M Platt DH | 2005 | J Cell Sci2005，118，1： | 1 |
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