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| 1 | Recent advances in dietary supplementation, in treating non-alcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD) is currently known as the most common liver problem, characterized by excessive lipid accumulation in hepatocytes,which may progress to other liver diseases such as nonalcoholic steatohepatitis, hepatic tissue fibrosis, livercirrhosis, and failure or hepatocellular carcinoma. Since NAFLD is positively associated with the development of obesity, insulin resistance, and ultimately type 2 diabetes mellitus, it is often regarded as the hepatic manifestation of the metabolic syndrome. No pharmacologic treatment has yet been proven for this disease. For most patients with presumed or confirmed NAFLD, the only proven strategy is to offer lifestyle advice that can lead to sustained weight loss. Since insulin resistance, oxidative stress, inflammation, and necro-apoptosis are involved in NAFLD pathogenesis, it seems that every potential therapeutic agent should target one or some of these pathologic events. There are many well known anti-oxidants, anti-inflammatory, and insulin sensitizer dietary supplements which have shown beneficial effects on NAFLD improvement in animal and human studies. The purpose of this review is to explore the existing evidences on dietary supplements considered to have hepatoprotective properties, and to present some proposed mechanisms by which they may protect against NAFLD. | Tannaz Eslamparast Sareh Eghtesad Hossein Poustchi Azita Hekmatdoost | 2015 | World Journal of Hepatology2015，7，2： | 26 |
| 2 | T2* magnetic resonance imaging of the liver in thalassemic patients in Iran显示文摘AIM: To investigate the accuracy of T2*-weighted magnetic resonance imaging (MRI T2*) in the evaluation of iron overload in beta-thalassemia major patients. METHODS: In this cross-sectional study, 210 patients with beta-thalassemia major having regular blood transfusions were consecutively enrolled. Serum ferritin levels were measured, and all patients underwent MRI T2* of the liver. Liver biopsy was performed in 53 patients at an interval of no longer than 3 mo after the MRIT2* in each patient. The amount of iron was assessed in both MRI T2* and liver biopsy specimens of each patient. RESULTS: Patients’ ages ranged from 8 to 54 years with a mean of 24.59 ± 8.5 years. Mean serum ferritin level was 1906 ± 1644 ng/mL. Liver biopsy showed a moderate negative correlation with liver MRI T2* (r = -0.573, P = 0.000) and a low positive correlation with ferritin level (r = 0.350, P = 0.001). Serum ferritin levels showed a moderate negative correlation with liver MRI T2* values (r = -0.586, P = 0.000). CONCLUSION: Our study suggests that MRI T2* is a non-invasive, safe and reliable method for detecting iron load in patients with iron overload. | Farhad Zamani Sara Razmjou Shahram Akhlaghpoor Seyyedeh-Masoomeh Eslami Azita Azarkeivan Afsaneh Amiri | 2011 | World Journal of Gastroenterology2011，17，4： | 8 |
| 3 | Dietary supplementation in patients with alcoholic liver disease: a review on current evidence显示文摘BACKGROUND:Alcoholic liver disease(ALD)is one of the main causes of liver disease worldwide.Although the pathogenesis of ALD has not yet been well elucidated,the oxidative metabolites of ethanol such as acetaldehyde and reactive oxygen species play a pivotal role in the clinical and pathological spectrum of the disease.This review summarizes the existing evidences on dietary supplements considered to have antioxidant,and/or anti-inflammatory properties,and their role in the management of ALD and the proposed mechanisms.DATA SOURCES:The present study reviewed all studies published in Pub Med,Science Direct and Scopus,from 1959 to2015,indicating the role of different dietary supplementation in attenuation of many pathophysiological processes involved in development and progression of ALD.Full-texts of citations were used except for those that were published in languages other than English.RESULTS:Significant progress has been made to understand the key events and molecular players for the onset and progression of ALD from both experimental and clinical studies;however,there is no successful treatment currently available.The present review discussed the role of a variety of dietary supplements(e.g.vitamin A,carotenoids,vitamins B3,C and E,in addition to antioxidants and anti-inflammatory agents)in treating ALD.It has been shown that supplementation with some carotenoids,vitamin B3,vitamin C,silymarin,curcumin,probiotics,zinc,S-adenosylmethionine and garlic may havepotential beneficial effects in animal models of ALD;however,the number of clinical studies is very limited.In addition,supplementation should be accompanied with alcohol cessation.CONCLUSIONS:Since oxidative stress and inflammation are involved in the pathogenesis of ALD,dietary supplements that can modulate these pathologies could be useful in the treatment of ALD.In addition to alcohol cessation,these supplements have shown beneficial effects on animal models of ALD.Clinical trials are needed to validate the beneficiary role of these supplements in patients with ALD. | Zeinab Ghorbani Masoomeh Hajizadeh Azita Hekmatdoost | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，4： | 8 |
| 4 | Egg consumption and risk of non-alcoholic fatty liver disease显示文摘AIM To evaluate the association between egg consumption and risk of non-alcoholic fatty liver disease(NAFLD) development.METHODS This case-control study was conducted on individuals who were referred to two hepatology clinics in Tehran, Iran in 2015. The study included 169 patients with NAFLD and 782 controls. Egg consumption was estimated using a validated food frequency questionnaire. The participants were categorized according to the frequency of their egg consumption during the previous year: Less than two eggs per week, two to three eggs per week, and four or more eggs per week.RESULTS In the crude model, participants who consumed 2 to 3 eggs per week, were 3.56 times more likely to have NAFLD in comparison to those who consumed less than 2 eggs per week(OR: 3.56; 95%CI: 2.35-5.31). Adjustment for known risk factors of NAFLD strengthenedthis significant association so that individuals have consumed two to three eggs per week had 3.71 times higher risk of NAFLD than those who have eaten less than two eggs per week(OR: 3.71; 95%CI: 1.91, 7.75). CONCLUSION Our data indicate that higher egg consumption in common amount of usage is associated with higher risk of NAFLD. | Zeinab Mokhtari Hossein Poustchi Tannaz Eslamparast Azita Hekmatdoost | 2017 | World Journal of Hepatology2017，9，10： | 3 |
| 5 | Dietary supplements and pediatric non-alcoholic fatty liver disease: Present and the future显示文摘Non-alcoholic fatty liver disease(NAFLD) is the most common chronic liver disease in children.High prevalence of pediatric obesity and sedentary lifestyle has augmented the incidence of NAFLD in children.Obesity is associated with an increased risk of NAFLD through various mechanisms such as intensification of insulin resistance and increased levels of inflammatory markers.There is no approved medical intervention for treatment of pediatric NAFLD;the only proven strategy in management of pediatric NAFLD is lifestyle modification.Recently,the effects of nutritional supplements have been examined in the management of pediatric NAFLD.The purpose of this review is to summarize the studies evaluating the effects of nutritional supplements on pediatric NAFLD and explain the future direction in this field. | Mehran Rahimlou Hoda Ahmadnia Azita Hekmatdoost | 2015 | World Journal of Hepatology2015，7，25： | 3 |
| 6 | An Investigation About Misconceptions in Force and Motion in High School显示文摘 | Azita Seyed Fadaei Cesar Mora | 2015 | US-China Education Review(A)2015，5，1： | 2 |
| 7 | Sleep quality in university students with Premenstrual Dysphoric Disorder显示文摘 | Habibolah KHAZAIE Mohammad Rasoul GHADAMI Behnam KHALEDI-PAVEH Azita CHEHRI Marzieh NASOURI | 2016 | 上海精神医学2016，28，3： | 1 |
| 8 | Pre-operative blood donation versus acute normovolemic hemodilution in cardiac surgery显示文摘 | Mohammad Nobahar Azita Chegini Faranak Behnaz | 2014 | Saudi Journal of Anaesthesia2014，，3： | 1 |
| 9 | Determination of lead, cadmium and arsenic in infusion tea cultivated in north of Iran显示文摘 | Sakine S Mahboobeh G Azita M | 2012 | Iranian Journal of Environmental Health Sciences & Engineering2012，9，： | 1 |
| 10 | On the metal–insulator transition in vanadium dioxide显示文摘 | Shigeji Fujita Azita Jovaini Salvador Godoy Akira Suzuki | 2012 | Physics Letters A2012，，44： | 1 |
| 11 | Tribulus terrestris-induced severe nephrotoxicity in a young healthy male显示文摘 | Talasaz Azita Hajhossein Abbasi Mohammad-Reza Abkhiz Saeed | 2010 | Nephrology Dialysis Transplantation2010，25，11： | 1 |
| 12 | Repair of alveolar cleft defect with mesenchymal stem cells and platelet derived growth factors: A preliminary report显示文摘 | Hossein Behnia Arash Khojasteh Masoud Soleimani Azita Tehranchi Amir Atashi | 2011 | Journal of Cranio-Maxillofacial Surgery2011，，1： | 1 |
| 13 | The theoretical framework of cultural competence显示文摘 | Maria Jirwe Kate Gerrish Azita Emami | 2006 | Journal of Multicuhural Nursing & Health2006，15，： | 1 |
| 14 | Alan Winters, 'Transport Costs and 'Natural' Integration in Mercosur' 显示文摘 | Azita Amjadi and L | 1999 | Journal of Economic Integration 14 (4 December)1999，，： | 1 |
| 15 | Thrust Density Characteristics of Linear DC Motor 显示文摘 | M Norhisam A noor Azita Ji Syed | | IEEE PEDS0，1005，： | 1 |
| 16 | The prevalenceof mediterranean mutation of glucose-6-phosphatedehydrogenase ( G6PD ) in Zahedan显示文摘 | Alireza N Saeedeh S Azita Z | 2012 | Zahedan Journal ofResearch in Medical Sciences2012，14，3： | 1 |
| 17 | Allele and haplotype frequencies for HLA-DQ in Iranian celiac disease patients显示文摘AIM:To assess the distribution of human leukocyteantigen(HLA)-DQ2 and-DQ8 in Iranian celiac disease(CD)patients and compare them to healthy Iranian controls.METHODS:To predict the HLA-DQA1 and-DQB1genes,we used six previously reported HLA-tagging single nucleotide polymorphism to determine HLA genotypes in 59 Iranian patients with‘biopsy-confirmed’CD and in 151 healthy Iranian individuals.To test the transferability of the method,50 cases and controls were also typed using a commercial kit that identifies individual carriers of DQ2,DQ7 and DQ8 alleles.RESULTS:In this pilot study 97%of CD cases(n=57)and 58%of controls(n=87)were carriers of HLADQ2 and/or HLA-DQ8 heterodimers,either in the homozygous or heterozygous state.The HLA-DQ pattern of these 57 CD patients:heterozygous DQ2.2(n=14)and homozygous DQ2.2(n=1),heterozygous DQ2.5(n=33)and homozygous DQ2.5(n=8),heterozygous DQ8(n=13)and homozygous DQ8(n=2).Two CD patients were negative for both DQ2 and DQ8(3%).CONCLUSION:The prevalence of DQ8 in our CD population was higher than that reported in other populations(25.4%).As reported in other populations,our results underline the primary importance of HLA-DQ alleles in the Iranian population’s susceptibility to CD. | Mohammad Rostami-Nejad Jihane Romanos Kamran Rostami Azita Ganji Mohammad Javad Ehsani-Ardakani Ali-Reza Bakhshipour Homayoun Zojaji Seyed Reza Mohebbi Mohammad-Reza Zali Cisca Wijmenga | 2014 | World Journal of Gastroenterology2014，20，20： | 1 |
| 18 | The prevalenceof mediterranean mutation of dlucose-6-phosphatedehydrogenase ( G6PD ) in Zahedan显示文摘 | Alireza N Saeedeh S Azita Z | 2012 | Zahedan Journal ofResearch in Medical Sciences2012，14，3： | 1 |
| 19 | Effect of ultrasound on enzymatic activity of selected plasminogen activators显示文摘 | Azita Soltard Charles Soliday | 2007 | Thlombosis Research2007，，119： | 1 |
| 20 | Correlation between HBsAg quantitative assay re- suits and HBV DNA levels in chronic HBV显示文摘 | Azita G Abbas E | 2011 | Hepat Mon2011，11，5： | 1 |
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