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| 1 | Deep learning with convolutional neural networks for identification of liver masses and hepatocellular carcinoma: A systematic review显示文摘BACKGROUND Artificial intelligence,such as convolutional neural networks(CNNs),has been used in the interpretation of images and the diagnosis of hepatocellular cancer(HCC)and liver masses.CNN,a machine-learning algorithm similar to deep learning,has demonstrated its capability to recognise specific features that can detect pathological lesions.AIM To assess the use of CNNs in examining HCC and liver masses images in the diagnosis of cancer and evaluating the accuracy level of CNNs and their performance.METHODS The databases PubMed,EMBASE,and the Web of Science and research books were systematically searched using related keywords.Studies analysing pathological anatomy,cellular,and radiological images on HCC or liver masses using CNNs were identified according to the study protocol to detect cancer,differentiating cancer from other lesions,or staging the lesion.The data were extracted as per a predefined extraction.The accuracy level and performance of the CNNs in detecting cancer or early stages of cancer were analysed.The primary outcomes of the study were analysing the type of cancer or liver mass and identifying the type of images that showed optimum accuracy in cancer detection.RESULTS A total of 11 studies that met the selection criteria and were consistent with the aims of the study were identified.The studies demonstrated the ability to differentiate liver masses or differentiate HCC from other lesions(n=6),HCC from cirrhosis or development of new tumours(n=3),and HCC nuclei grading or segmentation(n=2).The CNNs showed satisfactory levels of accuracy.The studies aimed at detecting lesions(n=4),classification(n=5),and segmentation(n=2).Several methods were used to assess the accuracy of CNN models used.CONCLUSION The role of CNNs in analysing images and as tools in early detection of HCC or liver masses has been demonstrated in these studies.While a few limitations have been identified in these studies,overall there was an optimal level of accuracy of the CNNs used in segmentation and classification of liver cancers images. | Samy A Azer | 2019 | World Journal of Gastrointestinal Oncology2019，11，12： | 10 |
| 2 | Inflammatory bowel disease: An evaluation of health information on the internet显示文摘AIM To evaluate the quality and accuracy of websites written to the public on inflammatory bowel disease(IBD)(Crohn's disease and ulcerative colitis) and assess their readability level.METHODS Google?, Bing?, and Yahoo? search engines were searched independently by three researchers in December 2014. Only English-language websites were selected on the basis of predetermined inclusion and exclusion criteria. Researchers independently evaluated the quality of each website by using the DISCERN and the HONcode instruments. The readability levels were calculated using two formulas; the Flesch-Kincaid Grade Level Index, and the Coleman-Liau Readability Index. The agreement between the evaluators was calculated using Cohen kappa coefficient.RESULTS Eighty-four websites were finally identified. Scores varied from a minimum DISCERN score of 18 to a maximum of 68 [mean ± SD, 42.2 ± 10.7; median = 41.5, interquartile range, interquartile range (IQR) = 15.8] and a minimum score of HONcode of 0.14 and a maximum of 0.95 (mean ± SD, 0.16 ± 0.19; median = 0.45, IQR = 0.29). Most of these websites were reviewed in 2014 and 2015 (n = 51). The creators of these websites were: universities and research centers(n = 25, 30%), foundations and associations (n = 15, 18%), commercial and pharmaceutical companies(n =25, 30%), charities and volunteer work(n = 9, 10%), and non-university educational bodies (n = 10, 12%). The Flesch-Kincaid Grade Level readability score(mean ± SD) was 11.9 ± 2.4 and the Coleman-Liau Readability Index score was 12.6 ± 1.5. Significant correlation was found between the two readability scores (R2 = 0.509, P = 0.001). The overall agreement between evaluators measured by Cohen kappa coefficient was in the range of 0.804-0.876; rated as 'Good'.CONCLUSION The DISCERN and the HONcode scores of websites varied and the readability levels of most websites were above the public readability level. The study highlights the areas that need further improvement and development in patient education online materials about IBD. | Samy A Azer Thekra I AlOlayan Malak A AlGhamdi Malak A AlSanea | 2017 | World Journal of Gastroenterology2017，23，9： | 4 |
| 3 | Detection of class 1 integron in Acinetobacter baumannii isolates collected from nine hospitals in Turkey显示文摘Objective:To investigate the antibiotic resistance genes inserted into class I and class 2integrons in Acinetobacler baumannii[A.baumannii)isolates obtained from nine different cities in Turkey.Methods:A collection of 281 A.baumannii clinical isolates were collected from nine diferenl state hospitals in Turkey and were confirmed as A.baumannU by conventional biochemical,API testing and bla_(-OXA-51)specific PCR.The isolates were examined by PCR for existence of class I and2 integron gene cassettes.Results:They were characterized by antimicrobial susceptibility testing and the highest resistance rates were determined for piperacillin(90.03%),ciprofloxacin(87.54%),cefepime and trimethoprim/sulfamethoxazole(81.13%).The lowest resistance rates was for cefotaxime(3.55%).class 1 integrons were detected in 6.4%(18/281)of A.baumannii strains and no class 2 integron was detected.The gene casselles of class 1 inlegrons AacCI-AAC(3)l-aadAI,AacCI-aadA1,AAC(3)-I,AAC(3)-I-AAC(3)-I-aadA1,TEM-1.AAC(3)-I-aadA1-AAC(3)-I-AAC(3)-I,AAC(3)-I-AAC(3)-I-AAC(3)-I-aadA1,AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I,AAC(3)-I-aadA1-AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I-aadA1-AAC(3)-I-aadA1 were detected in eighteen strains.The aac genes family were most frequently found integrated into the class 1 inlegrons and it was followed by aadA genes and TEM-1 genes.Conclusions:This is an extensive study on the distribulion of class 1 integron among A.baumannii in Turkey.In addition to these,two new alleles were observed.Their percentage rates of similarity to other cassettes are 95%aadA1(TK A18)and 89%,aadA 1(ANKA3). | Aysegül Copur Cicek Azer Ozad Düzgün Aysegül Saral Tuba Kayman Zeynep Cizmeci Pervin Ozlem Balci Tuba Dal Mehmet Firat Ismail Tosun Yasemin Ay Alitntop Ahmet Caliskan Yelda Yazici Cemal Sandalli | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，9： | 3 |
| 4 | Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development显示文摘 | Samy A. Azer | 2013 | European Journal of Gastroenterology & Hepatology2013，，3： | 3 |
| 5 | LONG-TIME DYNAMICS OF THE STRONGLY DAMPED SEMILINEAR PLATE EQUATION IN R^N显示文摘We investigate the initial-value problem for the semilinear plate equation containing localized strong damping, localized weak damping and nonlocal nonlinearity. We prove that if nonnegative damping coefficients are strictly positive almost everywhere in the exterior of some ball and the sum of these coefficients is positive a.e. in R^n, then the semigroup generated by the considered problem possesses a global attractor in H^2(R^n) × L^2(R^n).We also establish the boundedness of this attractor in H^3(R^n) × H^2(R^n). | Azer KHANMAMEDOV Sema YAYLA | 2018 | Acta Mathematica Scientia2018，38，3： | 3 |
| 6 | Self-Similarity in World Wide Web Traffic:Evidence and Possible Causes显示文摘 | Mark E Crovella Azer Bestavros | 1997 | IEEE/ACM Transactions on Networking1997，6，83： | 1 |
| 7 | A novel 3-dimensional micro-ultrasound approach to automated measurement of carotid arterial plaque volume as a biomarker for experimental atherosclerosis显示文摘 | Matthew Walker Barry R. Campbell Karim Azer Christopher Tong Kaijie Fang Jacquelynn J. Cook Michael J. Forrest Kimberly Kempadoo Samuel D. Wright Jeffrey S. Saltzman Euan MacIntyre Richard Hargreaves | 2009 | Atherosclerosis2009，，1： | 1 |
| 8 | Modeling thermal spray coating processes: a powerful tool in design and optimization 显示文摘 | MOSTAGHIMI J CHANDRA S GHAFOUR AZER R | 2003 | Surf Coat Technol2003，16，： | 1 |
| 9 | Effect of oil on heat transfer and pressure drop during condensation of refrigerant-113 inside smooth and internally finned tues 显示文摘 | Sur B Azer N Z | 1991 | ASHRAE Trans1991，97，： | 1 |
| 10 | Becoming a student in PBL course: twelve tips for successful group discussion显示文摘 | Azer SA | 2004 | Medical Teacher2004，26，： | 1 |
| 11 | MR imaging for surgical planning and postoperative assessment in early osteoarthritis显示文摘 | Azer NM Winalski CS Minas T | 2004 | Radiol Clin North Am2004，42，1： | 1 |
| 12 | Interactions between students and tutor in prob- lem - based learning: the significance of deep learning 显示文摘 | Azer SA | 2009 | Kaohsiung J Med Sci2009，25，5： | 1 |
| 13 | Modification of suction-induced hemolysis during cell salvage 显示文摘 | Waters JH Williams B azer MH | 2007 | Anesth- Ans2007，104，3： | 1 |
| 14 | Augmentation of condensation heat transfer with in-line static mixers 显示文摘 | Azer N Z Fan L T Lin S T | 1976 | Heat Transfer and Fluid Mech Inst Stanford Univ1976，26，： | 1 |
| 15 | Interactions between students and tutor in problem-basedleaming : the significance of deep learning显示文摘 | Azer SA | 2009 | Kaohsiung J Med Sci2009，25，5： | 1 |
| 16 | Twelve tips for construc- ting problem - based learning cases 显示文摘 | Azer SA Peterson R Guerrero AP | 2012 | Med Teach2012，34，5： | 1 |
| 17 | Learning surface anatomy :which learning approach is effective in an integrated PBL curriculum显示文摘 | Azer SA | 2011 | Med Teach2011，33，1： | 1 |
| 18 | lnteroducing a problem-based Learning program 12 tips for sucess显示文摘 | Azer S A | 2011 | Medical Teacher2011，33，10： | 1 |
| 19 | The natriuretic peptides BNP and CNP increase heart rate and electrical conduction by stimulating i- onic currents in the Sinoatrial node and atrial myocardium following activation of guanylyl cyclase - 1 inked natriuret ic pept ide recep- tors显示文摘 | Springer J Azer J Hua R | 2012 | J Mol Cell Cardiol2012，2，1： | 1 |
| 20 | Introducing a problem-based learning program: 12 tips for success显示文摘 | AZER SA | 2011 | Med Teacher2011，33，10： | 1 |
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