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| 1 | Inhibitory effect of Phlai capsules on skin test responses among allergic rhinitis patients:a randomized,three-way crossover study显示文摘BACKGROUND: Zingiber cassumunar Roxb., commonly known as Phlai in Thai, has been used as a traditional medicine in Thailand for the treatment of various diseases, including inflammation and chronic airway disease. OBJECTIVE: The purpose of this study was to assess the antihistaminic effect of Phlai on skin testing.DESIGN, SETTING, PARTICIPANTS AND INTERVENTION: This was a randomized, open-label, threeway crossover study. Twenty allergic rhinitis(AR) patients were enrolled. In randomized sequence, patients received a single dose of Phlai capsules(100 or 200 mg) or loratadine(10 mg) with a washout period of 1 week between each treatment.MAIN OUTCOME MEASURES: Skin prick testing for histamine and common aeroallergen(house dust mite) were performed before treatment and after 1, 2, 3, 4, 6, 8, 12 and 24 hours of treatment. The main treatment outcomes were the mean wheal and flare responses to the skin prick test after treatment.RESULTS: Both 100 mg and 200 mg Phlai doses suppressed wheal and flare responses to house dust mite allergen, but only 200 mg of Phlai capsules significantly suppressed wheal and flare responses to histamine. Repeated measures analysis of variance showed that loratadine caused more wheal and flare suppression than Phlai capsules in responses to the histamine skin prick test. However, there were no significant differences among the effects of 100 mg Phlai capsules, 200 mg Phlai capsules and loratadine in suppression of wheal and flare induced by the mite skin prick test. Both doses of Phlai were well-tolerated with no adverse events.CONCLUSION: Both 100 mg(compound D 4 mg) and 200 mg(compound D 8 mg) Phlai capsules, when taken as a single therapeutic dose, inhibited skin reactivity to histamine and mite skin prick tests in AR patients.TRIAL REGISTRATION: Thai clinical trial registry(TCTR20160510001). | pattara tanticharoenwiwat prapasri kulalert thaweephol dechatiwongse na ayudhya sittichai koontongkaew weena jiratchariyakul ruedee soawakontha prakongsiri booncong orapan poachanukoon | 2017 | Journal of Integrative Medicine2017，15，6： | 3 |
| 2 | Pharmacokinetic parameters of total and unbound valproic acid and their relationships to seizure control in epileptic children显示文摘 | Panomvana Na Ayudhya D Suwanmanee J Visudtibhan A | 2006 | Am J Ther2006，13，3： | 1 |
| 3 | NaOH改性WO_3/SiO_2催化剂催化2-丁烯和乙烯复分解制丙烯(英文)显示文摘A WO3 /SiO2 catalyst is used in industry to produce propylene from 2-butene and ethylene metathe-sis. Catalysts with various WO3 loading(4% to 10%) were prepared by impregnation and tested for the metathesis of ethene and trans-2-butene. Ion exchange of NaOH onto the WO3/SiO2 catalyst was used to mitigate the acidity of the catalysts in a controlled way. At low WO3 loading, the treatment with large amounts of NaOH resulted in a significant decrease in metathesis activity concomitant with significant W leaching and marked structural changes(XRD, Raman). At higher WO3 loading (6% to 10%), the treatment with NaOH mainly resulted in a decrease in acidity. FT-IR experiments after adsorption of pyridine showed that the Lewis acidic sites were poisoned by sodium. Never-theless, the metathesis activity remained constant after the NaOH treatment. This suggested that the remaining acidity on the catalyst was enough to ensure the efficient formation of the carbene active sites. Interestingly, Na poisoning resulted in some modification of the selectivity. The mitigation of acidity was shown to favor propene selectivity over the formation of isomerization products (cis-2-butene, 1-butene, etc.). Moreover, treatment with NaOH led to a shorter induction period and reduced coke formation on the WO3 /SiO2 catalyst. | Surasa Maksasithorn Damien P. Debecker Piyasan Praserthdam Joongjai Panpranot Kong- kiat Suriye Sirachaya Kunjara Na Ayudhya | 2014 | 催化学报2014，35，2： | 1 |
| 4 | Effect of aging on the properties of mesoporous niobium oxide显示文摘 | Ayudhya S K N Soottitantawat A Praserthdam P | 2008 | Materials ChemistryandPhysics2008，110，23： | 1 |
| 5 | Pregnancy outcome of twin pregnancy in Ramathibodi Hospital 显示文摘 | Chittacharoen A Singhakun D Ayudhya N I | 2006 | J Med Assoc Thai2006，89，4： | 1 |
| 6 | One-step purification of chimeric green fluorescent protein providing metal-binding avidity and protease recognition sequence显示文摘 | Prachayasittikul V Isarankura Na Ayudhya C Piacham T | 2003 | Asian Pac J Allergy Immunol2003，21，4： | 1 |
| 7 | Phannacokinetic parameters of total and unbound valproic acid and their relationships to seizure control inepileptic children显示文摘 | Panomvana Na Ayudhya D Suwanmanee JA | | 0，，03： | 1 |
| 8 | NSP2gene variation of the North American genotype of the Thai PRRSVin central Thailand显示文摘 | Kedkovid R Nuntawan Na Ayudhya S Amonsin A | 2010 | Virol J2010，7，1： | 1 |
| 9 | Prognostic factors for success in treating kidney stones by extracorporeal shock wave lithotripsy显示文摘 | Chongruksut W Lojanapiwat B Ayudhya V C | 2011 | J Med As- soc Thai2011，94，3： | 1 |
| 10 | Prognosticfactors for success in treating kidney stones by extracorporeal shock wave lithotripsy显示文摘 | Chongruksut W Lojanapiwat B Ayudhya VC | 2011 | J Med Assoc Thai2011，94，3： | 1 |
| 11 | Pharmacokinetic parameters of total and unbound valproic acid and their relationships to seizure control inepileptic children显示文摘 | Panomvana Na Ayudhya D Suwanmanee J Visudtibhan A | 2006 | Am J Ther2006，13，3： | 1 |
| 12 | Randomized controlled trial of glove perforation in single- and double-gloving in episiotomy repair after vaginal delivery 显示文摘 | Punyatanasakchai P Chittacharoen A Ayudhya NI | 2004 | J Obstet Gynaecol Res2004，30，5： | 1 |
| 13 | 显示文摘 | Sirachaya Kunjara Na Ayudhya Parawee Tonto Okorn Mekasuwandumrong | 2006 | Crys Growth Des2006，6，11： | 1 |
| 14 | 查看详情显示文摘 | Ayudhya S K N Tonto P Mekasuwandumrong O | | 0，，： | 1 |
| 15 | Molecular docking of aromatase inhibitors 显示文摘 | SUVANNANG N NANTASENAMAT C ISARANKURA - NA - AYUDHYA C | 2011 | Molecules2011，16，5： | 1 |
| 16 | Effect of rifampicn on the pharmacokinetics of fluconazole inpatients with AIDS 显示文摘 | Panomvana Na Ayudhya D Thanompuangseree N TansuphaswadikulS | 2004 | Clin Pharmacokinet2004，43，11： | 1 |
| 17 | Compressive and splitting tensile strength of autoclaved aerated concrete (AAC)containing perlite aggregate and polypropylene fiber subjected to high temperatures显示文摘 | NA AYUDHYA B I | 2011 | Sci- ence Technology2011，，5： | 1 |
| 18 | Solvothermal synthesis of ZnO with various aspect ratios using organic solvents显示文摘 | Ayudhya S K N Tonto P Mekasuwandumrong O | | 0，，11： | 1 |
| 19 | Bone Metastasis in Cervical Cancer Patients Over a 10-Year Period显示文摘 | Duangmani Thanapprapasr Adisak Nartthanarung Puchong Likittanasombut Nathpong Israngura Na Ayudhya Chuenkamon Charakorn Umaporn Udomsubpayakul Thanya Subhadarbandhu Sarikapan Wilailak | 2010 | International Journal of Gynecological Cancer2010，，： | 1 |
| 20 | LEGAL DISPUTES OF MARITIME BOUNDARIESDIMENSIONAL CASE STUDY OF THE THAILANDCAMBODIA显示文摘 | Kaweepol Sawangpaew Pimprapai Snitwong Na Ayudhya | 2014 | US-China Law Review2014，11，11： | 0 |
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