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| 1 | A rapid method for estimating log P for organic chemicals显示文摘 | Veith G D Austin N M and Morris R T | 1979 | Water Res1979，13，： | 3 |
| 2 | Bacterial growth state distinguished by single-cell protein profiling:dose chlorination kill coliforms in municipal effluent 显示文摘 | Rockabrand D Austin T Kaiser B | 1999 | Appl Environ Microbiol1999，65，： | 2 |
| 3 | Evolutionary relationships among the Braconidae (Hymenoptera: Ichneumonoidea)inferred from partial 16S rDNA gene sequences显示文摘 | DOWTON M AUSTIN A D ANTOLIN M F | 1998 | Insect Mol Bio1998，7，2： | 2 |
| 4 | Enhanced caveolin-1 expression in smooth muscle cells: Possible prelude to neointima formation显示文摘AIM: To study the genesis of neointima formation in pulmonary hypertension(PH), we investigated the role of caveolin-1 and related proteins. METHODS: Male Sprague Dawley rats were given monocrotaline(M, 40 mg/kg) or subjected to hypobaric hypoxia(H) to induce PH. Another group was given M and subjected to H to accelerate the disease process(M + H). Right ventricular systolic pressure, right ventricular hypertrophy, lung histology for medial hypertrophy and the presence of neointimal lesions were examined at 2 and 4 wk. The expression of caveolin-1 and its regulatory protein peroxisome proliferator-activated receptor(PPAR) γ, caveolin-2, proliferative and antiapoptotic factors(PY-STAT3, p-Erk, Bcl-x L), endothelial nitric oxide synthase(e NOS) and heat shock protein(HSP) 90 in the lungs were analyzed, and the results from M + H group were compared with the controls, M and H groups. Double immunofluorescence technique was used to identify the localization of caveolin-1 in pulmonary arteries in rat lungs and in human PH lung tissue. RESULTS: In the M + H group, PH was more severe compared with M or H group. In the 4 wk M+H group, several arteries with reduced caveolin-1 expression in endothelial layer coupled with an increased expression in smooth muscle cells(SMC), exhibited neointimal lesions. Neointima was present only in the arteries exhibiting enhanced caveolin-1 expression in SMC. Lung tissue obtained from patients with PH also revealed neointimal lesions only in the arteries exhibiting endothelial caveolin-1 loss accompanied by an increased caveolin-1 expression in SMC. Reduction in e NOS and HSP90 expression was present in the M groups(2 and 4 wk), but not in the M + H groups. In both M groups and in the M + H group at 2 wk, endothelial caveolin-1 loss was accompanied by an increase in PPARγ expression. In the M + H group at 4 wk, increase in caveolin-1 expression was accompanied by a reduction in the PPARγ expression. In the H group, there was neither a loss of endothelial caveolin-1, eNOS or HSP 90, nor an increase in SMC caveolin-1 expression; or any alteration in PPARγ expression. Proliferative pathways were activated in all experimental groups. CONCLUSION: Enhanced caveolin-1 expression in SMC follows extensive endothelial caveolin-1 loss with subsequent neointima formation. Increased caveolin-1 expression in SMC, thus, may be a prelude to neointima formation. | Jing Huang John H Wolk Michael H Gewitz James E Loyd James West Eric D Austin Rajamma Mathew | 2015 | World Journal of Cardiology2015，7，10： | 2 |
| 5 | Roles of DnaK and RpoS in starvation-induced thermotolerance of Escherichia coli 显示文摘 | Rockabrand D K Livers T Austin R | 1998 | J Bacteriol1998，180，： | 1 |
| 6 | A pilot study to investigate the use of oxpentifylline (pentoxifylline) and thalidomide in portal hypertension secondary to alcoholic cirrhosis 显示文摘 | Austin AS Mahida YR Clarke D | 2004 | Aliment Pharmacol Ther2004，19，1： | 1 |
| 7 | Wideband Statistics of Signal Levels and Doppler Spread on an Over-the-sea Transhorizon Link显示文摘 | NDZI D AUSTIN J VILAR E | 1997 | IEE Seminar Digests1997，，： | 1 |
| 8 | Less invasive technique for mitral valve surgery 显示文摘 | Carpentier A Cho PW Berrebi A d'Attellis N Austin CB Couetil JP Lajos P | 1998 | J Thorac Cardiovasc Surg1998，115，4： | 1 |
| 9 | Phosphorus losses in irrigation from fertilized pasture显示文摘 | Austin N R Prendergast J B Collins M D | 1996 | Journal of Environ- mental Quality1996，25，： | 1 |
| 10 | Genetic improvements in winter wheat yields since 1900 and associated physiological changes 显示文摘 | AUSTIN R B BINGHAM J BLACKWELL R D | 1980 | J Agric Sci1980，94，： | 1 |
| 11 | Complex for- mation and ion ieeonductivity of polyphosphazene solid elee- trolytes显示文摘 | Blonsky P M Shriver D F Austin P E | 1986 | Solid State Ionies1986，18，： | 1 |
| 12 | PCR detection of a putati-e N - acetylmuramidase gene from Listeria i-ano-ii facilitates its rapid identification 显示文摘 | Liu D Ainsworth A J Austin F W | 2004 | Vet Micro- biol2004，101，2： | 1 |
| 13 | Clearing the air: The costs and consequences of higher CAFE standards and increased gasoline taxes显示文摘 | Austin D Dinan T | 2005 | Journal of Environmental Economics and Management2005，50，3： | 1 |
| 14 | Effects of flue-curing and ageing on the volatile,natural and acidic constituents of Virginia tobacco显示文摘 | Wahlberg I Kerstin K Austin D J | 1977 | Pyhtochemistry1977，16，： | 1 |
| 15 | The percentage of consonants correct (PCC) metric : Extensions and reliability data显示文摘 | Shriberg LD Austin D Lewis BA | 1997 | J Speech Lang Hear Res1997，40，4： | 1 |
| 16 | Long - term radar observations of the melting layer of precipitation and their interpretation 显示文摘 | Fabry R Austin G L Tees D | 1995 | At- mos Sci1995，52，： | 1 |
| 17 | A reassessment of the phylogenetic relationships within the Microgastrinae (Hymenoptera :Braconidae)显示文摘 | KITCHING I J AUSTIN A D | 1990 | Cladistics1990，6，： | 1 |
| 18 | SimpleScalar:An Infrastructure for Computer System Modeling显示文摘 | Austin T Larson E Ernst D | 2002 | IEEE Computer2002，35，2： | 1 |
| 19 | 显示文摘 | Zhang L Austin D Merkulov V I | 2004 | Appl Phys Lett2004，84，： | 1 |
| 20 | Association of sleep apnea and type H diabetes:a population-basedstudy 显示文摘 | Reichmuth KJ Austin D Skatrucl JB | 2005 | Am J Respir CritCare Med2005，172，12： | 1 |
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