6篇
您的检索式：作者名="Atul Sachdev"
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| 1 | GC/MS-based differential metabolic profiling of human peptic ulcer disease to study Helicobacter pylori-induced metabolic perturbations显示文摘Helicobacter pylori infection has been significantly linked to Peptic Ulcer Disease and Gastric Cancer.Metabolomic fingerprinting may offer a principal way of early diagnosis and to understand the molecular mechanism of H.pylori-induced pathogenicity.The rationale of the study is to explore the underlying distinct metabolic mechanisms of H.pylori-induced PUD and to identify potential biomarkers for disease diagnosis and associated risks using Gas chromatography/mass spectrometry.GC/MS-based analytical method was used to compare metabolic profiles of healthy controls(N=20)and peptic ulcer patients(N=45).Acquired metabolomic data were analyzed by constructing a diagnostic model using principal component analysis and a non-parametric two-tailed paired Wilcoxon analysis to identify disease-specific metabolic biomarkers.A total of 75 low-molecular-weight endogenous metabolites were detected during comparative metabolomic analysis of PUD vs.healthy gut tissues,among which 16 metabolites are being proposed to be diagnostic markers of Human PUD.Perturbations related to amino acids,carbohydrates,fatty acids,organic acids,and sterol metabolism were significantly revealed during this differential metabolomic profiling.Results convincingly suggest that metabolic profiles can contribute immensely in early diagnosis of the disease and understanding molecular mechanisms of disease progression for predicting novel drug targets for prophylactic and anaphylactic measures. | GAGANJOT GUPTA DEEPAK BANSAL ANSHULA SHARMA TAWSEEF AHMAD ATUL SACHDEV AJAZ AHMAD HAMED A.EL-SEREHY BALJINDER KAUR | 2021 | BIOCELL2021，45，5： | 2 |
| 2 | Cerebral Fat Embolism as a Rare Possible Complication of Traumatic Pancreatitis显示文摘 | Atul Sachdev Sarabmeet Singh Lehl etal | 2003 | J Pancreas2003，，： | 1 |
| 3 | Effect of the Oral Intake of Probiotic Pediococcus acidilactici BA28 on Helicobacter pylori Causing Peptic Ulcer in C57BL/6 Mice Models显示文摘 | Baljinder Kaur Neena Garg Atul Sachdev Balvir Kumar | 2014 | Applied Biochemistry and Biotechnology2014，，2： | 1 |
| 4 | Adverse drug reactions & their risk factors among Indian ambulatory elderly patients 显示文摘 | Sanjay D'Cruz Atul Sachdev Pramil Tiwari | 2012 | The Indi- an journal of medical research2012，136，3： | 1 |
| 5 | 门静脉高压伴Cullen征及Turner征显示文摘一例患有酒精性肝硬化和门静脉高压的34岁男性患者出现腹胀、腹痛2周。体检发现Cullen征(脐周淤斑,附图A)、Grey-Turner征(肋腹部淤斑,附图B)及腹水。似乎可以作出急性胰腺炎的诊断,因为Cullen征及Grey—Turner征均与严重的坏死性胰腺炎相关。实验室检查显示贫血,白细胞及血小板计数正常,轻度凝血象紊乱,国际标准化比值为1.6。血清淀粉酶、脂肪酶和甲胎蛋白水平均在正常范围。 | Sandeep Chauhan Manisho Gupta Atul Sachdev San jay D'Cruz Ikjot Kaur 范懿(译) | 2008 | 世界临床医学2008，2，5： | 0 |
| 6 | 米氏线显示文摘一19岁男性因足部及面部浮肿3个月就诊,否认有端坐呼吸、夜间发作性呼吸困难、少尿、血尿、发热、咽喉炎、关节痛、皮疹等病史及重金属暴露史和药物滥用史。一般查体:眶周皮肤肿胀、苍白,甲板上出现水氏线(附图),足部肿胀。全身检查未见明显异常。 | Sandeep Chauhan Sanjay D'Cruz Ram Singh Atul Sachdev 李兆伟(译) | 2009 | 世界临床医学2009，3，1： | 0 |
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