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| 1 | Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis显示文摘AIM To observe the inhibition of antisenseoligonucleotides (asON) phosphorthioate to thetissue inhibitors metalloproteinase-1 (TIMP-1)gene and protein expression in the liver tissue ofimmunologically induced hepatic fibrosis rats.The possibility of reversing hepatic fibrosisthrough gene therapy was observed.METHODS Human serum albumin (HSA) wasused to attack rats, as hepatic fibrosis model, inwhich asONs were used to block the gene andprotein expressing TIMP-1. According to theanalysis of modulator, structure protein, codingseries of TIMP-1 genome, we designed fourdifferent asONs. These asONs were injected intothe hepatic fibrosis models through coccygealvein. The results was observed by RT-PCR formeasuring TIMP-1 mRNA expression,immunohistochemistry and in situ hybridizationfor collagen Ⅰ, Ⅲ, special staining of collagenfiber, and electron microscopic examination.RESULTS Hepatic fibrosis could last within 363days in our modified model. The expressinglevel of TIMP-1 was high during hepatic fibrosisprocess. It has been proved by theimmunohistochemical and the electronmicroscopic examination that the asONphosphorthioate of TIMP-1 could exactly expressin vivo. The effect of colchicine wasdemonstrated to inhibit the expressing level ofmRNA and the content of collagen Ⅰ, Ⅲ in theliver of experimental hepatic fibrosis rats.However, the electron microscopy research andthe pathologic grading of hepatic fibrosisshowed that there was no significant differencebetween the treatment group and the modelgroup (P>0.05).CONCLUSION The experimental rat model ofhepatic fibrosis is one of the preferable modelsto estimate the curative effect of anti-hepaticfibrosis drugs. The asON phosphorthioate ofTIMP-1 could block the gene and proteinexpression of TIMP-1 in the liver of experimentalhepatic fibrosis rats at the mRNA level. It ispossible to reverse hepatic fibrosis, and it isexpected to study a new drug of anti-hepaticfibrosis on the genetic level. Colchicine has verylimited therapeutic effect on hepatic fibrosis,furthermore, its toxicity and side effects areobvious. | Qing He Nie Yong Qian Cheng Yu Mei Xie Yong Xing Zhou Yi Zhan Cao The Center of Infectious Disease Diagnosis and Treatment of PLA,Tangdu Hospital,Forth Military Medical University,Xi’an 710038,Shaanxi Province,ChinaDr,Qing He Nie graduated from Qinghai Medical College as a doctor in 1983,got master degree at Beijing 302 Army Hospital in 1993,got doctor degree at the Third Military Medical University in 1998,engaged in postdoctoral research at the Fourth Military Medical University from 1998 to 2000,now an associate professor,specialized in clinical and experimental research of infectious diseases,had more than 90 papers published,coauthor of ten books,first author of one book. | 2001 | World Journal of Gastroenterology2001，7，3： | 73 |
| 2 | Expansion of Rural Construction in Suburbs of Beijing:A Case Study on Nanjuan Village of Shunyi显示文摘1. Background Today the rural land use in China calls for major concerns. Villages in suburban areas, due to their special location, are experiencing dramatic changes on | ZHANG Yue,PhD,Associate Professor,School of Architecture,Tsinghua University,Beijing,P. R. China. CAO Wen,Undergraduate,School of Architecture,Tsinghua University,Beijing,P. R. China. ZHANG Lu,Undergraduate,School of Architecture,Tsinghua University,Beijing,P. R. China. LAN Weijie,Undergraduate,School of Architecture,Tsinghua University,Beijing,P. R. China. | 2007 | China City Planning Review2007，16，4： | 34 |
| 3 | Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultured rat hepatocytes显示文摘AIM To study the effects of aminoguanidine(AG) and two L-arginine analogues Nω-nitro-L-arginine methyl ester (L-NAME) and Nω-nitro-L-arginine (L-NNA) on nitric oxide (NO) productioninduced by cytokines (TNF-α, IL-11β, and IFN-γ)and bacterial lipopolysaccharide (LPS) mixture(CM) in the cultured rat hepatocytes, andexamine their mechanisms action.METHODS Rat hepatocytes were incubatedwith AG, L-NAME, L-NNA, Actinomycin D (ActD)and dexamethasene in a medium containing CM(LPS plus TNF-α, IL-1β, and IFN-γ) for 24 h. NOproduction in the cultured supernatant wasmeasured with the Griese reaction. IntracellularcGMP level was detected with radioimmunoasey.RESULTS NO production was markedlyblocked by AG and L-NAME in a dose-dependentmanner under inflammatory stimuli conditiontriggered by CM in vitro. The rate of themaximum inhibitory effects of L-NAME (38.9%)was less potent than that obtained with AG(53.7%, P<0.05). There was no significantdifference between the inhibitory effects of AGand two L-arginine analogues on intracellularcGMP accumulation in rat cultured hepatocytes.Non-specific NOS expression inhibitordexamethasone ( DEX ) and iNOS mRNAtranscriptional inhibitor ActD also significantlyinhibited CM-induced NO production. AG(0.1mmol.L-1) and ActD (0.2ng@Lt) wereequipotent in decreasing NO production inducedby inflammatory stimuli in vitro, and botheffects were more potent than that induced bynon-selectivity NOS activity inhibitor L-NAME(0. 1 mmol@ L- 1) under similar stimuli conditions(P | Guo Liang Zhang Ye Hong Wang Hui Ling Teng Zhi Bin Lin Department of Pharmacology,School of Basic Medical Sciences,Beijing University,Beijiog 100083,ChinaDr.Guo Liang Zhang graduated from Xinxiang Medical College in 1982,got Ph.D.at Nagoya City University Medical School,Japan in 1994,finished postdoctoral research at Beijing Medical Univcrsity in 1996,now an associate professor of pharmacology,specialized in hepatic pharmacology,having 15 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 20 |
| 4 | Orthotopic transplantation model of human gastrointestinal cancer and detection of micrometastases显示文摘AIM To establish a relevant animal model ofhuman gastrointestinal cancer, which can beused for repetitive investigations, so as toimprove our understanding and management ofcarcinogenesis and cancer metastasis.METHODS Intact tissues of human colorectaland pancreatic cancers were transplanted innude mice. The biological characteristics of theoriginal and the corresponding transplantedtumors were investigated by HE staining, PASstaining and immunostaining. The metastases inthe livers and lungs of nude mice wereinvestigated by immunostaining withbiotinylated mab KL-1 and by RT-PCR using CK20specific primers.RESULTS There were totally 9 of 16 surgicalspecimens growing in nude mice subcutaneouslyand/.or orthotopically (4 of 6 colorectal and 5 of10 pancreatic cancer). Tumor cell content of thespecimens and freezing of tissue specimens areimportant factors influencing the growth oftransplanted tumor. In the group of fresh tumortissues with greater than 50% tumor cellcontent, the success rate of the transplantationwas 100% (3 cases of pancreatic cancer and 3cases of colorectal cancer). The orthotopicallytransplanted tumors resemble the original tumormorphologically and biologically, including TAAexpression such as CEA byimmunohistochemistry, and CEA level in theserum of mice. Ki-67 labeling index and theexpression of TAA especially K-ras, 17-lA andRA-96, are associated with the potential of tumorgrowth in nude mice. Micrometastases in thelungs and livers of tumor bearing mice can bedetected by immunostaining with biotinylatedmab KL-1 and CK20-specific RT-PCR.CONCLUSION An orthotopic transplantationmodel for human colon and pancreatic cancer innude mice has been set up. We have alsoestablished sensitive detection methods withCK-immunohistochemistry and CK20-RT-PCR tostudy xenotransplanted human cancer and itsmetastatic cancer cells in the liver and lung ofnude mice. This study may be helpful inunderstanding the mechanism of cancermetastasis and in developing new diagnosticmethods and therapeutic strategies formetastases including micrometastases. | Jun Hui Cui~1 Uwe Krueger~2 Doris Henne-Bruns~2 Bemd Kremer~2 Holger Kalthoff~2 ~1Department of General Surgery,First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003,Zhejiang Province,China ~2Department of General Surgery,Christian-Albrechts-University,Kiel,GermanyDr.Jun Hui Cui graduated from Zhejiang Medical University in 1984,earned master degree in 1990,studied in the Surgical Department of Kiel University and worked in the Lab of Molecular Oncology of Kiel University from 1994-1997achieved M.D.from Kiel University.Germany,now associate professor of surgery,specialized in colorectal oncology.Adviser of graduated student for master degree,having 20 publications published in key Chinese or English journals. | 2001 | World Journal of Gastroenterology2001，7，3： | 19 |
| 5 | Virulence and potential pathogenicity of coccoid Helicobacter pylori induced by antibiotics显示文摘AIM To explore the virulence and the potential pathogenicity of coccoid Helicobacter pylori (H. pylori) transformed from spiral form by exposure to antibiotic.METHODS Three strains of H. pylori, isolated from gastric biopsy specimens of confirmed peptic ulcer, were converted from spiral into coccoid from by exposure to metronidazole.Both spiral and coccoid form of H. pylori were tested for the urease activity, the adherence to Hep-2 cells and the vacuolating cytotoxicity to Hela cells, and the differences of the protein were analysed by SDS-PAGE and Western blot,The mutation of the genes including ureA, ureB,hpaA; vacA and cagA, related with virulence,was detected by means of PCR and PCR-SSCP.RESULTS In the coccoid H. pylori, the urease activity, the adherence to Hep-2 cells and the vacuolating cytotoxicity to Hela cells alldecreased. In strain F44, the rate and index of adherence reduced from 70.0% ± 5.3% to 33% ±5.1% and from 2.6 ±0.4 to 0.96 ±0.3 (P<0.01),respectively. The invasion of coccoid H. pylori into Hep-2 cell could be seen under electronmicroscope. SDS-PAGE showed that the content of the protein with the molecular weight over Mr74 000 decreased, and the hybriditional signal in band Mr 125 000 weakened, while the band Mr 110000 and Mr63000 strengthened in coccoid H. pylori as shown in Western blot. The results of PCR were all positive, and PCR-SSCP indicated that there may exist the point mutation in gene hpaA or vacA.CONCLUSION The virulence and the proteins with molecular weight over Mr74 000 in coccoid H. pylori decrease, but no deletion exists in amplification fragments from ureA, ureB, hpaA,vacA and cagA genes, suggesting that coccoid H. pylori may have potential pathogenicity. | Fei Fei She1 Dong Hui Su1 Jian Yin Lin2 Lin Ying Zhou3 1Department of Microbiology, Fujian Medical University. Fuzhou 350004, Fujian Province, China2Department of Molecular Medicine, Fujian Medical University, Fuzhou 350004, Fujian Province, China 3Laboratory of Electron Microscope, Fujian Medical University, Fuzhou 350004. Fujian Province. ChinaFei Fei She. graduated from Fujian Medical University as a postgraduate in 1991, now associate professor of microbiology and immunology, specialized in molecular biology of pathogen, having 15 papers published. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 6 | Reliability-Based Design for Jacket Platform Under Extreme Loads显示文摘In this paper, reliability analysis for the offshore jacket platform with the interaction of structure- pile- soil under extreme environmental loads is carried out. The inherent uncertainties of the environmental load, foundation soil, platform itself, and calculating models are evaluated. The action of extreme loads on the offshore platform is modeled as a function of extreme wave height. The system capacity of the whole platform is determined by nonlinear pushover analysis, and the relevant probability property is obtained by the simulation method. The reliability model for the whole jacket platform is described as the relationship between the load and resistance based on the offshore design codes. The reliability of whole platform is calculated by the analytical method and the importance sampling method on the basis of a case study for a tripod jacket platform. | Jin Weiliang Associate Professor, Dr. -Eng., Zhejiang University, Hangzhou 310027 | 1996 | China Ocean Engineering1996，11，2： | 17 |
| 7 | Emergency assessment of seismic landslide susceptibility: a case study of the 2008 Wenchuan earthquake affected area显示文摘The 8.0 Mw Wenchuan earthquake triggered widespread and large scale landslides in mountainous regions.An approach was used to map and assess landslide susceptibility in a given area.A numerical rating system was applied to fi ve factors that contribute to slope instability.Factors such as lithology,topography,streams and faults have an important influence as event-controlling factors for landslide susceptibility assessment.A f inal map is provided to show areas of low,medium,and high landslide susceptibility.Areas identifi ed as having high landslide susceptibility were located in the central,northeastern,and far south regions of the study area.The assessment results will help decision makers to select safe sites for emergency placement of refuges and plan for future reconstruction.The maps may also be used as a basis for landslide risk management in the study area. | Tang Chuan,Zhu Jing and Liang Jingtao State Key Laboratory of Geo-Hazard Prevention,Chengdu University of Technology,Chengdu 610059,China Professor Associate Professor Graduate Student | 2009 | Earthquake Engineering and Engineering Vibration2009，8，2： | 16 |
| 8 | The Bedload Movement in the Changjiang Estuary显示文摘- Sandwaves in the Changjiang estuary were measured with a shallow sediment profiler and an echosounder from 1978 to 1988. The data, together with grain size and bedform of sediment indicates that the bedload movement by rolling and saltation is of great significance to sediment transport and is the principal factor responsible for sandwave and sandbody development in the estuary. The sandwaves were found well-developed, which is related to the tidal range and the velocity of ebb current. However, the further growth is restricted by strong flood current prevailing in the estuary. Because of the significant bedload, the sandbodies shift obviously and frequently, and sometimes the exchange of position occurs between the sandbodies and tidal channels. As a result, ships are regularly forced to change their navigation course. | Li Jiufa, Shi Weirong, Shen Huanting Xu Haigen and Doeke Eisma Associate Professor, Institute of Estuarine & Coastal Research (1ECR), East China Normal University, Shanghai200062 Professor, IECR, East China Normal University, Shanghai 200062 Professor, Netherlands Institute for Sea Research, P. O. Box 59 1790 AB, Den Burg, Texel, The Netherlands | 1993 | China Ocean Engineering1993，8，4： | 15 |
| 9 | Ecological Planning for Sino-Singapore Ecological Science and Technology Town of Suzhou显示文摘1. Background The construction of Sino-Singapore Ecological Science and Technology Town (SSESTT), which is a part of Suzhou Industrial Park, was initiated in 2005 under the circumstance of rapid | LIN Borong, Associate Professor, School of Architecture, Tsinghua University, Beijing, P. R. China. QIN Youguo, Professor, School of Architecture, Tsinghua University, Beijing, P. R. China. LIU Ligang, PhD Candidate, School of Architecture, Tsinghua University, Beijing, P. R. China. SONG Yehao, Associate Professor, School of Architecture, Tsinghua University, Beijing, P. R. China. | 2008 | China City Planning Review2008，17，4： | 12 |
| 10 | Dynamic Response Behaviors of Upright Breakwaters Under Breaking Wave Impact显示文摘- The dynamic response behaviors of upright breakwaters under broken wave impact are analysed based on the mass-damper-spring dynamic system model. The effects of the mass, damping, stiffness, natural period, and impulse duration (or oscillation period) on the translation, rotation, sliding force, overturning moment, and corresponding dynamic amplifying factors are studied. It is concluded that the ampli-ying factors only depend on the ratio of the system natural period to impulse duration (or oscillation period) under a certain damping ratio. Moreover, the equivalent static approach to breakwater design is also discussed. | Wang Yuanzhan , Chi Lihua and Pan Houzhi Associate Professor, Department of Water Resources and Harbour Engineering, Tianjing University, Tianjin 300072Lecturer, Computer Center, Tianjing University, Tianjin 300072 Graduate student, Department of Water Resources and Harbour Engineering, Tianjing University, Tianjin 300072 | 1996 | China Ocean Engineering1996，11，3： | 12 |
| 11 | Preliminary analysis of the hanging wall effect and velocity pulse of the 5.12 Wenchuan earthquake显示文摘A preliminary study of the PGA attenuation, hanging wall effect and velocity pulse characteristics from the 2008 Wenchuan earthquake of Ms =8.0 is described in this paper. The study was carried out through analyses in the time and frequency domains of main earthquake records. In the PGA attenuation study, records from 316 stations less than 1000 km from the surface rupture of the fault were used as a database and attenuation relationships were developed and compared with some existing relationships that are widely used in China's Mainland, Chinese Taiwan and the US. At the same time, records from 28 stations less than 100 km from the fault were used to study the hanging wall effect and velocity pulse characteristics of this earthquake based on the distribution of PGA, PGV, spectral acceleration, and the velocity pulse peak, and the results are compared with the 1999 Chi-Chi earthquake. In addition, the large PGAs of the UD components observed in this event are also discussed in this paper. From the results of the preliminary study, some conclusions are developed and suggestions for further research are proposed. | Liu Qifang and Li Xiaojun Institute of Engineering Mechanics, China Earthquake Administration, Harbin 150080, China Associate Professor Professor | 2009 | Earthquake Engineering and Engineering Vibration2009，8，2： | 11 |
| 12 | Housing Wealth, Financial Wealth and Consumption in China显示文摘纸在城市的中国在财产财富和家庭消费的趋势运动调查在变化之间的关系。用向量错误修正 cointegration 模型,我们证明在城市的中国在家庭消费,可处理的收入,金融财富和住房财富之间有一种唯一的长期间 cointegrating 关系。当 cointegrated 系统被外部震动扰乱时,我们发现住房财富是恢复长期间平衡关系的唯一的因素。另外,我们的永久临时的变化分解分析都显示那在消费的运动的变化是永久的,支持消费行为的古典随机的散步假设。然而,在住房财富的短期的运动的变化的一个大比例被发现临时。 | Jie Chen Feng Guo Aiyong Zhu Associate Professor,School of Management,Fudan University,Shanghai,China. Senior Research Economist and Economics Lecturer,Haile/US Bank College of Business,Northern Kentucky University,Highland Heights,USA. Master Student,School of Economics,Fudan University,Shanghai,China. | 2009 | China & World Economy2009，17，3： | 10 |
| 13 | Inflammatory pseudotumor of the liver: 13 cases of MRI findings显示文摘INTRODUCTIONInflammatory pseudotumor of the liver ,a rare benign lesion ,is often confused with the malignant tumors .Until 1998,less than 80 cases had been reported in the world [1,2].The accuracy of the pre-surgical diagnosis was low p[3,4] ,and very few materials on the diagnosis using dynamic MRI were reported [5-7] .We collected thirteen cases of inflammatory pseudotumor of the liver were collected and roved by pathology with MRI studies .Our purpose is to describe and analyze the MRI findings of this lesion and find out the valuable signs suggesting the diagnosis so as to avoid unnecessary operations. | Fu Hua Yan Kang Rong Zhou Ya Ping Jiang Wei Bin Shi Department of Radiology,Zhongshan Hospital,Medical Center of Fudan University (Former Shanghai Medical University),180 Fenglin Road,Shanghai 200032,ChinaDr.Fu Hua Yan graduated from Shanghai Medical University as a postgraduate in 1996,now an associated professor,a radiologist in chief specialized in the diagnosis of CT and MRI in hepatic diseases,having 22 papers published.She is the associated editor of the books Spiral CT and Body MRI. | 2001 | World Journal of Gastroenterology2001，7，3： | 8 |
| 14 | China’s WUB Community vs. America’s TOD Community显示文摘1. Critiques and reflections on WUB CommunityThe working unit system and the WUB Community, i.e., working-unit-based community, are two completely | YU Wenbo,Postdoctoral,Department of Architecture,Zhejiang University Associate Professor,Department of Architecture and Planning,Zhejiang University of Technology,Hangzhou,P. R. China. WANG Zhu,Professor,Chair of Department of Architecture,Zhejiang University,Hangzhou,P. R. China. MENG Haining,Associate Professor,Chair of Department of Architecture,Zhejiang University,Hangzhou,P. R. China. Editorial Department | 2007 | China City Planning Review2007，16，4： | 7 |
| 15 | A Unique Solvable Higher Order BEM for Wave Diffraction and Radiation显示文摘- For the discretization of higher order elements, this paper presents a modified integral domain method to remove the irregular frequencies inherited in the integral equation of wave diffraction and radiation from a surface-piercing body. The set of over-determined linear equations obtained from the method is modified into a normal set of linear equations by superposing a set of linear equations with zero solutions. Numerical experiments have also been carried out to find the optimum choice of the size of the auxiliary domain and the discretization on it. | Teng Bin and Li Yucheng Associate Professor, Dept. of Civil Engineering, Dalian University of Technology, Dalian, 116024 Professor, Dept. of Civil Engineering, Dalian University of Technology, Dalian, 116024 | 1996 | China Ocean Engineering1996，11，3： | 6 |
| 16 | ECONOMIC GROWTH AND CYCLES IN MODERN CHINA显示文摘If the theory of cyclical fluctuation can be applied to modern China, the economic development ofChina in this period can be seen as consisting of several stages. At each stage as well as in the wholeperiod, chosen index system is likely to help measure the growth rate. By vertical and horizontal com-parison, this paper will try to settle the disputes on China’s modern economic development. | Liu Foding Wang Yuru Yu Jianwei 1937- Professor of Institute of Economics of NANKAI UNIVERSITY. Supervisor to Ph. D. candidates Ph. D. of Economics. Associate Professor of Institute of Economics of NANKAI UNIVERSITY Master of economics. Lecturer of Department of Economics atSICHUAN UNIVERSITY | 1994 | 南开经济研究1994，，S3： | 6 |
| 17 | Three-Dimensional Tidal Model and Its Application to Numerical Simulation of Water Quality in Coastal Waters显示文摘- The turbulence mechanism plays an important part in the mixing process and momentum transfer of turbulence. A three-dimensional Prandtl mixing length tidal model has been developed to simulate tidal flows and water quality. The eddy viscosities and diffusivities are computed from the Prandtl mixing length model. In order to model the water quality of an estuary or coastal area many interdependent processes need to be simulated. These may be conveniently separated into three main groups: transport and mixing processes, biochemical interaction of water quality variables and the utilization and re-cycling of nutrients by living matter. The model simulates full oxygen and nutrient balance, primary productivity and the transport, reaction mechanism and fate of pollutants over tidal time-scales. The model is applied to numerical simulation of tidal flows and water quality in Dalian Bay. The model has been calibrated against a limited data set of historical water quality observations and in general | Shen Yongming , Li Yucheng and Zhao Wenqian Associate Professor, Department of Civil Engineering, Dalian University of Technology, Dalian 116023 Professor, Department of Civil Engineering, Dalian University of Technology, Dalian 116023 Professor, Department of Civil Engineering, Sichuan Union University, Chengdu 610065 | 1994 | China Ocean Engineering1994，9，4： | 5 |
| 18 | Investigation on Settling Characteristics of Floes in the Changjiang Estuary, China显示文摘- Settling characteristics of floes, including relative settling velocity, relative flocculation coefficient and flocculation exponent, are obtained by the suspended load equations for different size fractions. Data of the Changjiang Estuary suggest that level of flocculation changes from river section, river mouth (turbidity maximum) to offshore area in sequence of low, very high and high. The settling characteristics of floes reflected by in situ estimation performs a similar feature as that obtained from still water experiment. | Li Yan, Wang Yaqin LinYian Associate Professor, Second Institute of Oceanography, State Oceanic Administration, Hangzhou, 310012 Senior Engineer, Second Institute of Oceanography, State Oceanic Administration, Hangzhou, 310012 | 1995 | China Ocean Engineering1995，10，3： | 5 |
| 19 | Recent Progress in Image Coding显示文摘RecentProgresinImageCodingFanChangxinLuZhaoyang(XidianUniversity,Xi’an710071)AbstractTheworksonimagecodinginrecenttwoye... | Fan ChangxinFan Changxin is with Xidian University, Professor,FCIC,FCIE,FIEE,FIEEE Lu ZhaoyangLu Zhaoyang is with Xidian University, Ph.D.,Associate Researcher (Xidian University, Xi’an 710071) | 1998 | 通信学报1998，19，5： | 5 |
| 20 | VELOCITY PROFILES OF SEDIMENT-LADEN FLOW显示文摘The time-average velocity profiles of the flows carrying natural sand particles and three kinds of plastic particles as suspension and neutrally buoyant load are measured and analyzed. The velocity profiles of the sediment-laden flow can approximately be divided into two regions - the near-bed region and the far-bed region. Main factors affecting the velocity profiles are viscosity, density gradient, grain shear stress and damping of turbulence due to particles. Based on these physical conceptions, a velocity profile model of sediment-laden flow is developed. It agrees well with the experimental data. The discrepancy is 1.57% for the plastic particle-laden flow and 3.67% for the natural sand-laden flow. In the far-bed region, von Karman constants are smaller than those of the clear water flow. | WANG Xingkui and QIAN Ning (N. Chien) (Associate Professor, Department of Hydraulic Engineering, Tsinghua University, Beijing,100084, China Late Professor, Department of Hydraulic Engineering, Tsinghua University, Beijing,100084, China) | 1992 | International Journal of Sediment Research1992，7，1： | 4 |
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