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| 1 | Proposed case of mesalazine-induced cardiomyopathy in severe ulcerative colitis显示文摘Five-amino salicylic acids are recommended for use in the management of inflammatory bowel disease,cardiac complications are a rare although recognised phenomenon.This report aims to highlight this serious but rare adverse reaction.We report here a case of a young man presenting with cardiogenic shock in the context of recent mesalazine treatment in severe ulcerative colitis. | Kathryn Fleming Andrew Ashcroft Christopher Alexakis Demitrios Tzias Christopher Groves Andrew Poullis | 2015 | World Journal of Gastroenterology2015，21，11： | 9 |
| 2 | 局部应用吡美莫司和他克莫司治疗异位性皮炎的疗效和耐受性:随机对照实验的Meta分析 | Ashcroft D.M. Dimmock P. Garside R. 刘燕 | 2005 | 世界核心医学期刊文摘(皮肤病学分册)2005，0，7： | 3 |
| 3 | BMC Medicine论文摘要汇编——风险预测模型评估的不确定性对治疗决策影响的队列研究:以英国基层医疗机构心血管病患者为例显示文摘背景风险预测模型通常在临床中用于辅助决策。但是,目前很少有研究对于风险预测模型评估超出可信区间(CI)的风险评分的不确定性进行探讨。本文旨在对采用基于QRISK预测工具建立的不同风险预测模型评估的患者发病风险的不确定性进行分析。方法从英国临床研究数据库选取3 792 474例具有住院治疗数据及死亡记录、符合研究要求并可以进行心血管病(CVD)风险评估的患者。采用建立QRISK 2和QRISK 3模型的方法建立风险预测模型(模型A^F),然后校正可能导致各模型预测能力差异的因素以及填补缺失数据后再进行预测。比较各模型的十年风险评分以及一般性能。结果不同模型评估患者CVD风险结果有显著差异。模型A评估男性CVD风险95%CI为(4.4%,16.3%)、女性为(4.6%,15.8%),模型F评估患者CVD风险95%CI为(9%,10%)。一般性能指标评价各模型预测能力相似(Harrell’s C=0.86~0.87)。造成各模型风险预测能力差异最大的因素为CVD发病长期趋势,校正此因素后,女性发病风险预测HR差异可降低0.96(0.95,0.96),男性可降低0.96(0.96,0.96)。当使用模型对英国人群进行风险评估时,有380万人可能被重新归类到符合使用他汀类药物的患者人群。本研究的一个重要局限性是没有纳入CPRD数据库中缺失的可能因素,如饮食或体育活动等。结论基于日常资料对患者CVD发病风险的预测结果因模型而异。尽管各模型预测结果可存在很大的差异,但普通性能指标评价各模型的预测能力相似。在做临床决策时,还应考虑临床评估结果和其他风险因素。对CVD发病长期趋势因素,应做进一步研究。 | 本刊编辑部(整理) PATE A EMSLEY R ASHCROFT D M | 2019 | 中国全科医学2019，22，29： | 2 |
| 4 | Are meticillin-resistant Staphylococcus aureus bloodstream infection targets fair to those with other types of healthcare-associated infection or costeffective? 显示文摘 | Millar M Coast J Ashcroft R | 2008 | J Hosp Infect2008，69，1： | 1 |
| 5 | Clinical measures of disease severity and outcome in psoriasis:a critical appraisal of their quality显示文摘 | ASHCROFT D M WAN PO A L WILLIAMS H C | 1999 | Br J Dermatol1999，141，2： | 1 |
| 6 | Mice lacking Smad3 showaccelerated wound healing and an impaired local inflammatory response 显示文摘 | Ashcroft GS Yang X G|ick AB | 1999 | Nat Cell Biol1999，1，5： | 1 |
| 7 | Study of the preparationconditions for NiMn204 grown from hydroxide precursors 显示文摘 | ASHCROFT Q TERRY I GOVER R | 2006 | J EurCeram Soc2006，26，6： | 1 |
| 8 | Putting the Squeeze on Lithium 显示文摘 | Ashcroft N W | 2002 | Nature2002，419，6907： | 1 |
| 9 | Weighted-density-functional theory of inhomogeneous liquids and the freezing transition显示文摘 | Ashcroft N W | 1985 | Phys Rev1985，32，： | 1 |
| 10 | Stress signals utilize multiple pathways to stabilize p53显示文摘 | TAYA Y VOUSDEN H K | 2000 | Mol Cell Biol2000，20，9： | 1 |
| 11 | Reverse LISS plating for proximal segmental femoral fractures in the polytrauma patient: a case report显示文摘 | Pryce Lewis JR Ashcroft GP | 2007 | Injury2007，38，： | 1 |
| 12 | New windows on the mechanism of action of KATP channd opners显示文摘 | Ashcroft F M Gribble F M | 2000 | TiPS2000，21，： | 1 |
| 13 | Epidermal growth factor receptors in non-small cell lung cancer显示文摘 | Veale D Ashcroft T Marsh C | 1987 | Br J Cancer1987，55，3： | 1 |
| 14 | Topical estrogen accelerates cutaneous wound healing in aged humans associated with an altered inflammatory response显示文摘 | Ashcroft GS Greenwell-Wild T Horan MA | 1999 | Am J Pahol1999，155，4： | 1 |
| 15 | The relation between re- fitted radiation and yield on the broad balk winter wheat experi- ment显示文摘 | Ashcroft P M Catt J A Curran P J | 1990 | Int J Remote Sensing1990，11，10： | 1 |
| 16 | Potentiation of insulin hypoglycemia by MAOI antidepression drugs 显示文摘 | Cooper AJ Ashcroft G | 1966 | lancet1966，，： | 1 |
| 17 | Metallic Hydrogen显示文摘 | ASHCROFT N W | 1968 | Phys Rev Lett1968，21，： | 1 |
| 18 | The detection and identification of metal and organic pollutants in potable water using enzyme assays suitable for senor development显示文摘 | Cowell D C Dowman A A Ashcroft T | 1995 | Biosenors and Bioelectronics1995，10，67： | 1 |
| 19 | Diabetes mellitus and the 13 cell : the last ten years 显示文摘 | Ashcroft FM Rorsman P | 2012 | Cell2012，148，6： | 1 |
| 20 | The strength of female sex as a prognostic factor in small-cell lung cancer:a pooled analysis of chemotherapy trials from the Manchester lung group and medical research council clinical trials unit显示文摘 | Wheatley-Price P Ma C Ashcroft LF | | 0，，： | 1 |
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