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11篇 您的检索式:作者名="Arshaduddin"
    题名 作者 年代 出处 被引量
1Bromophenacyl bromide,a phospholipase A_2 inhibitor attenuates chemically induced gastroduodenal ulcers in rats显示文摘AIM: To study the effect of bromophenacyl bromide (BPB), a phospholipase A2 inhibitor on gastric secretion and to protect chemically induced gastric and duodenal ulcers in rats. METHODS: Acid secretion studies were undertaken in pylorus-ligated rats with BPB treatment (0, 5, 15 and 45 mg/kg). Gastric and duodenal lesions in the rats were induced by ethanol and cysteamine respectively. The levels of gastric wall mucus, nonprotein sulfhydryls (NP- SH) and myeloperoxidase (MPO) were also measured in the glandular stomach of rats following ethanol induced gastric lesions. RESULTS: BPB produced a dose-dependent inhibition of gastric acid secretion and acidity in rats. Pretreatment with BPB significantly attenuated the formation of etha- nol induced gastric lesion. BPB also protected intestinal mucosa against cysteamine-induced duodenal ulcers. The antiulcer activity of BPB was associated with signifi- cant inhibition of ethanol-induced depletion of gastric wall mucus, NP-SH and MPO. These findings pointed towards the mediation of sulfhydryls in BPB induced gas- trointestinal cytoprotection. CONCLUSION: BPB possesses significant antiulcer and cytoprotective activity against experimentally induced gastroduodenal lesions.Mohammad Tariq Ibrahim Elfaki Haseeb Ahmad Khan Mohammad Arshaduddin Samia Sobki Meshal Al Moutaery 2006World Journal of Gastroenterology2006,12,36:2
2Fluconazole attenuates lung injury and mortality in a rat peritonitis model显示文摘Mohammad Tariq Ahmed Al Moutaery Mohammed Arshaduddin Haseeb Ahmad Khan David Price Evans Sydney Jacobs 2003Intensive Care Medicine2003,,11:1
3Fluconazole attenuates lung injury and mortality in a rat peritonitis model显示文摘Mohammad Tariq Ahmed Al Moutaery Mohammed Arshaduddin Haseeb Ahmad Khan David Price Evans Sydney Jacobs 2003Intensive Care Medicine2003,,11:1
4Fluconazole attenuates lung injury and mortality in a rat peritonitis model显示文摘TARIQ M MOUTAERY A A ARSHADUDDIN M 2003Intensive Care Med2003,29,11:1
5Fluconazole attenuates lung injury and mortality in a rat peritonitis model显示文摘Tariq M Moutaery AA Arshaduddin M 2003Intensive Care Med2003,29,11:1
6Fluconazole attenuates lung injury and mortality in a rat peritonitis model显示文摘TARIQ M MOUTAERY A A ARSHADUDDIN M 2003Intensive Care Med2003,29,11:1
7Fluconazoleattenuates lung injury and mortality in a rat peritonitis model显示文摘Tariq M Moutaery A A Arshaduddin M 2003In-tensive Care Med2003,29,11:1
8Attenuation of acrylamide- induced neurotoxicity in diabetic rats 显示文摘Al DS Al MK Arshaduddin M 2000Neurotoxicol Teratol2000,22,:1
9Citalopram,a selective serotonin reuptake inhibitor augments harmaline-induced tremor in rats显示文摘Arshaduddin M Al Kadasah S Biary N 2004Behav Brain Res2004,153,:1
10Fluconazole attenuates lung injury and mortality in a rat peritonitis model 显示文摘Tariq M Moutaery AA Arshaduddin M 2003Intensive Care Med2003,29,11:1
11Vitamin Edecreases valproic acid induced neural tube defects in mice显示文摘A1 Deeb S Al Moutaery K Arshaduddin M 2000NeurosciLett2000,292,3:1
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