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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017,23,13: | 17 |
| 2 | S100B protein in tissue development,repair and regeneration显示文摘The Ca 2+-binding protein of the EF-hand type,S100B,exerts both intracellular and extracellular regulatory activities.As an intracellular regulator,S100B is involved in the regulation of energy metabolism,transcription,protein phosphorylation,cell proliferation,survival,differentiation and motility,and Ca 2+ homeostasis,by interacting with a wide array of proteins(i.e.,enzymes,enzyme substrates,cytoskeletal subunits,scaffold/adaptor proteins,transcription factors,ubiquitin E3 ligases,ion channels) in a restricted number of cell types.As an extracellular signal,S100B engages the pattern recognition receptor,receptor for advanced glycation end-products(RAGE),on immune cells as well as on neuronal,astrocytic and microglial cells,vascular smooth muscle cells,skeletal myoblasts and cardiomyocytes.However,RAGE may not be the sole receptor activated by S100B,the protein being able to enhance bFGF-FGFR1 signaling by interacting with FGFR1-bound bFGF in particular cell types.Moreover,extracellular effects of S100B vary depending on its local concentration.Increasing evidence suggests that at the concentration found in extracellular fluids in normal physiological conditions and locally upon acute tissue injury,which is up to a few nM levels,S100B exerts trophic effects in the central and peripheral nervous system and in skeletal muscle tissue thus participating in tissue homeostasis.The present commentary summarizes results implicating intracellular and extracellular S100B in tissue development,repair and regeneration. | Guglielmo Sorci Francesca Riuzzi Cataldo Arcuri Claudia Tubaro Roberta Bianchi Ileana Giambanco Rosario Donato | 2013 | World Journal of Biological Chemistry2013,4,1: | 14 |
| 3 | Longevi of fixed partial dentures 显示文摘 | Libby G Arcuri MR Lavelle WF | 1997 | J Prosthet Dent1997,78,: | 2 |
| 4 | Determination of cheese origin by using 16S rDNA fingerprinting of bacteria communities by PCR- DGGE: Preliminary application to traditional Minas cheese 显示文摘 | Arcuri EF E1 Sheikha AF Ryehlik T | 2013 | Food Control2013,30,1: | 1 |
| 5 | Macrophage migration inhibitory factor in prostatic adenocarcinoma:correlation with tumor grading and combination endocrine treatment-related changes显示文摘 | del Vecchio MT Tripodi SA Arcuri F Pergola L Hako L Vatti R | 2000 | Prostate2000,45,1: | 1 |
| 6 | Self- monitoring of blood glucose in a multiethnic population of rural older adults with diabetes显示文摘 | Skelly AH Arcury TA Snively BM | 2005 | Diabetes Edue Diabetes Res Clin Pratt2005,31,1: | 1 |
| 7 | Thromhin regulates soluble fms-like tyrosine kinase-1 (sFIt-l) expression in first trimester decidua: implications for preeclampsia显示文摘 | Lockwood CJ Toti P Arcuri F | 2007 | AmJ Pathol2007,170,4: | 1 |
| 8 | Environmental Attitude and Environmental Knowledge显示文摘 | Arcury T | 1990 | Human Organization1990,49,4: | 1 |
| 9 | Pharmacological management of cancer pain in the elderly 显示文摘 | MERCADANTE S ARCURI E | 2007 | Drugs Aging2007,24,9: | 1 |
| 10 | The translationally controlled tumor protein is a novel calcium binding protein of the human placenta and regulates calcium handling in trophoblast cells显示文摘 | Arcuri F Papa S Meini A | 2005 | Biol Reprod2005,73,4: | 1 |
| 11 | Breakthrough pain in cancer patients: pathophysiology and treatment 显示文摘 | Mercadante S Arcuri E | 1998 | Cancer Treat Rev1998,24,6: | 1 |
| 12 | The translationally controlled tumor protein is a novel calcium binding protein of the human placenta and regulates calcium handling in trophoblast cells显示文摘 | Arcuri F Papa S Meini A Carducci A Romagnoli R Bianchi L Riparbelli M G Sanchez J C Palmi M Tosi P Cintorino M | 2005 | Biol Reprod2005,73,4: | 1 |
| 13 | Determination of cheese origin by using 16S rDNA fingerprinting of bacteria communities by PCR-DGGE:preliminary application to traditional Minas cheese显示文摘 | ARCURI E F el SHEIKHA A F RYCHLIK T | 2013 | Food Control2013,30,: | 1 |
| 14 | Gas bubbles within acute intracranial epidural hematomas显示文摘 | Cossu M Arcuri T Cagetti B | 1990 | Acta Neurochir1990,102,12: | 1 |
| 15 | Propionyl-L-carnitine improves postischemic blood flow recovery and arteriogenetic revascularization and reduces endothelial NADPH-oxidase 4-mediated superoxide pro- duetion 显示文摘 | Stasi MA Scioli MG Arcuri G | 2010 | Arterioseler Thromb Vasc Biol2010,30,3: | 1 |
| 16 | Differential regulation of colony stimulating factor 1 and macrophage migration inhibitory fac- tor expression by inflammatory cytokines in term human decidua: implications for macrophage trafficking at the fetal-maternal inter- face 显示文摘 | Arcuri F Buchwalder L Toti P | 2007 | Biol Reprod2007,76,3: | 1 |
| 17 | Human decidual natural killer cells as a source and target of macrophage migration inhibitory factor显示文摘 | F Arcuri M Cintorino A Carducci | 2006 | Reproduction2006,131,: | 1 |
| 18 | Human Decidual Nat ural Killer Cells as A Source and Target of Macrophage Migra tionInhibitory Factor显示文摘 | Arcuri F Cintorino M Carducci A | 2006 | Reproduction2006,131,1: | 1 |
| 19 | Human decidual natural killer cells as a source and target of macrophage m igration inhibitory factor显示文摘 | Arcuri F Cintorino M Carducci A | 2006 | Rep roduction2006,131,: | 1 |
| 20 | Mechanisms of AbruptionInduced Premature Rupture of the Fetal Membranes:Thrombin-Enhanced Interleukin-8 Expression in Term Decidua显示文摘 | Lockwood CJ Toti P Arcuri F | | 0,,05: | 1 |