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| 1 | Clinical relevance of aberrant polypoid nodule scar after endoscopic submucosal dissection显示文摘AIM To describe a series of patients with aberrant polypoid nodule scar developed after gastric endoscopic submucosal dissection(ESD), and to discuss its pathogenesis and clinical management. METHODS We reviewed retrospectively the endoscopic database of two academic institutions located in Brazil and Japan and searched for all patients that underwent ESD to manage gastric neoplasms from 2003 to 2015. The criteria for admission in the study were:(1) successful en bloc ESD procedure with R0 and curative resection confirmed histologically;(2) postoperative endoscopic examination with identification of a polypoid nodule scar(PNS) at ESD scar;(3) biopsies of the PNS with hyperplastic or regenerative tissue, reviewed by two independent experienced gastrointestinal pathologists, one from each Institution. Data were examined for patient demographics, Helicobacter pylori status, precise neoplastic lesion location in the stomach, tumor size, histopathological assessment of the ESD specimen, and postoperative information including medical management, endoscopic and histological findings, and clinical outcome.RESULTS A total of 14 patients(10 men/4 women) fulfilled the inclusion criteria and were enrolled in this study. One center contributed with 8 cases out of 60 patients(13.3%) from 2008 to 2015. The second center contributed with 6 cases(1.7%) out of 343 patients from 2003 to 2015. Postoperative endoscopic follow-up revealed similar findings in all patients: A protruded polypoid appearing nodule situated in the center of the ESD scar surrounded by convergence of folds. Biopsies samples were taken from PNS, and histological assessment revealed in all cases regenerative and hyperplastic tissue, without recurrent tumor or dysplasia. Primary neoplastic lesions were located in the antrum in 13 patients and in the angle in one patient. PNS did not develop in any patient after ESD undertaken for tumors located in the corpus, fundus or cardia. All patients have been followed systematically on an annual basis and no malignant recurrence in the ESD scar has been identified(mean follow-up period: 45 mo).CONCLUSION PNS may occur after ESD for antral lesions and endoscopically look concerning, especially for the patient or the family doctor. However, as long as curative R0 resection was successfully achieved and histology demonstrates only regenerative and hyperplastic tissue, PNS should be viewed as a benign alteration that does not require any type of intervention, other than endoscopic surveillance. | Vitor Arantes Noriya Uedo Moises Salgado Pedrosa Yasuhiko Tomita | 2016 | World Journal of Gastrointestinal Endoscopy2016,8,17: | 4 |
| 2 | A role for synaptotagmin Ⅶ-regulated exocytosis of lysosomes in neurite outgrowth from primary sympathetic neurons 显示文摘 | Arantes RM Andrews NW | 2006 | J Neurosci2006,26,17: | 1 |
| 3 | Interaction of Saccha-romyces boulardii with Salmonella enterica serovar typhimurium protects miceand modifies T84 cell response to the infection 显示文摘 | Martins F S Dalmasso G Arantes R M E | 2010 | Plos One2010,5,1: | 1 |
| 4 | The lignin present in steam pretreated softwood binds enzymes and limits cellulose accessibility 显示文摘 | Linoj Kumar Valdeir Arantes Richard Chandra | 2012 | Bioresource Technology2012,,103: | 1 |
| 5 | The use of quilting suture in abdominoplasty does not require aspiratory drainage for pre- vention of seroma显示文摘 | Arantes HL Rosique RG Rosique MJ | 2010 | Aesthetic Plast Surg2010,34,1: | 1 |
| 6 | Enhanced pathogenicityof susceptible strains of the s Bacteroide fragilis group subjectedto low doses of metronidazole显示文摘 | DinizCG Arantes RM Cara DC | 2003 | Mierobes Infect2003,5,1: | 1 |
| 7 | Nuclear inosi- tol 1,4,5-trisphosphate is a necessary and conserved sig- nal for the induction of both pathological and physiological cardiomyocyte hypertrophy 显示文摘 | Arantes LA Aguiar C J Amaya M J | 2012 | J Mol Cell Cardiol2012,53,4: | 1 |
| 8 | Structural and functional assessment in HIV-infected patients using optical coherence tomography and frequency-doubling technology perimetry 显示文摘 | Faria E Arantes TE Garcia CR | 2010 | Am J Ophthalmol2010,149,4: | 1 |
| 9 | Advances in the management of early esophageal carcinoma显示文摘 | Arantes V Forero Pi~eros E A Yoshimura K | 2012 | Rev Col Bras Cir2012,39,6: | 1 |
| 10 | A study of the trypanocidal activity of triterpene acids isolated from Miconia species显示文摘 | Cunha WR Crevelin EJ Arantes GM | 2006 | Phytother Res2006,20,6: | 1 |
| 11 | Effect of different biofloc levels on microbial activity, water quality and performance of Litopenaeus vannamei in a tank system operated with no water exchange显示文摘 | Rodrigo Schveitzer Rafael Arantes Patrícia Fóes S. Costódio Carlos M. do Espírito Santo Luis Vinatea Arana Walter Quadros Seiffert Edemar Roberto Andreatta | 2013 | Aquacultural Engineering2013,,: | 1 |
| 12 | Conjunctival bacterial flora and antibiotic resist- ance pattern in patients undergoing cataract surgery 显示文摘 | Arantes TE Cavalcanti RF Diniz Mde F Severo MS Lins Neto J Castro CM | 2006 | Arq Bras Oftalmol2006,69,1: | 1 |
| 13 | Retinal angiography andcolour Doppler of retrobulbar vessels in Takayasu arteritis显示文摘 | Matos KT Arantes T Sou^ ^WV | 2014 | CanJ Ophthalmol2014,49,1: | 1 |
| 14 | Layout optimization with h-adaptivity of structures 显示文摘 | Arantes Costa Jr J C Alves M K | 2003 | International Journal for Numerical Methods in Engineering2003,58,1: | 1 |
| 15 | Distribution, abundance and diversity of Gambierdiscus spp. from a ciguatera-endemic area in Marakei, Republic of Kiribati显示文摘 | Yixiao Xu Mindy L. Richlen Steve L. Morton Yim Ling Mak Leo Lai Chan Aranteiti Tekiau Donald M. Anderson | 2014 | Harmful Algae2014,,: | 1 |
| 16 | Enhanced pathogenicity of susceptible strains of the Bacteroides fragilis group subjected to low doses of metronidazole 显示文摘 | DINIZ C G ARANTES R M CARA D C | 2003 | Microbes and Infection2003,5,1: | 1 |
| 17 | Preparation and characterization of solid dispersion of simvastatin 显示文摘 | Silav T D Arantes V T Resende J A | 2010 | Drug Dev lnd Pharm2010,14,6: | 1 |
| 18 | Ultrasonographic findings in ocular toxocariasis显示文摘 | Morais FB1 Maciel AL Arantes TE | 2014 | Arq Bras Oftalmol2014,75,1: | 1 |
| 19 | Standardized endoscopic submucosal tunnel dissection for management of early esophageal tumors (with video)显示文摘 | Vitor Arantes Walton Albuquerque Carlos Alberto Freitas Dias Monica Maria Demas Alvares Cabral Hironori Yamamoto | 2013 | Gastrointestinal Endoscopy2013,,: | 1 |
| 20 | Summary of the AUA Guideline on Management of Primary Vesicoureteral Reflux in Children显示文摘 | Peters CA Skoog SJ Arant BJ | | 0,,03: | 1 |