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| 1 | Parasite surveys and environmental management for prevention of parasitic infection in cultivated Barbonymus gonionotus (Cyprinidae) in fishponds, in an opisthorchiasis endemic area of northeast Thailand显示文摘 | Smarn Tesana Pairat Thabsripair Apiporn Suwannatrai Surat Haruay Supawadee Piratae Panita Khampoosa Chalida Thammasiri Sattrachai Prasopdee Jutharat Kulsantiwong Prapart Chalorkpunrut Malcolm K. Jones | 2014 | Aquaculture2014，，： | 1 |
| 2 | SPECIES-SPECIFIC PRIMERS DESIGNED FROM RAPD PRODUCTS FOR BITHYNIA FUNICULATA, THE FIRST INTERMEDIATE HOST OF LIVER FLUKE, OPISTHORCHIS VIVERRINI, IN NORTH THAILAND显示文摘 | Kulsantiwong Jutharat Prasopdee Sattrachai Piratae Supawadee Khampoosa Panita Suwannatrai Apiporn Duangprompo Wipada Boonmars Thidarut Ruangjirachuporn Wipaporn Ruangsittichai Jiraporn Viyanant Vithoon Hebert Paul D N Tesana Smarn | 2013 | The Journal of Parasitology2013，，3： | 1 |
| 3 | Repeated praziquantel treatment and Opisthorchis viverrini infection:a population-based cross-sectional study in northeast Thailand显示文摘Background:Opisthorchis viverrini infection is highly prevalent in northeast Thailand.This liver fluke is classified as a carcinogen due to its causal links with cholangiocarcinoma(CCA)development.Although treatment with praziquantel(PZQ)effectively cures O.viverrini infection,the prevalence remains high due to the traditional consumption of raw fish.Therefore,re-infection is common in the endemic community,leading to severe hepatobiliary morbidities including the fatal CCA.In this study,we evaluate the association between the frequency of previous PZQ treatment and current O.viverrini infections among Thai adults living in the endemic area of northeast Thailand.Methods:This study includes all participants who were screened for O.viverrini infection in the Cholangiocarcinoma Screening and Care Program(CASCAP),northeast Thailand.History of PZQ treatment was recorded using a health questionnaire.O.viverrini infections were diagnosed using urine antigen detection.Associations between PZQ and O.viverrini were determined by adjusted odds ratio(aOR)and 95%confidence interval(CI)using multiple logistic regression.Results:Among participants,27.7%had previously been treated once with PZQ,8.2%twice,2.8%three times,and 3.5%more than three times.Current O.viverrini prevalence was 17%(n=524).Compared with participants who never used PZQ,the aOR for infection among those who used the drug once was 1.09(95%CI:0.88-1.37),twice was 1.19(95%CI:0.85-1.68),three times was 1.28(95%C/:0.74-2.21),and more than three times was 1.86(95%C/:1.18-2.93;P=0.007).Conclusions:The population with a frequent history of PZQ use and still continued raw fish consumption showed high levels of repeated reinfection with O.viverrini.They were infected,treated and re-infected repeatedly.These findings suggest that certain participants continue raw fish consumption even after previous infection.This is a particular problem in highly endemic areas for O.viverrni and increases the risk of CCA. | Kavin Thinkhamrop Narong Khuntikeo Paiboon Sithithaworn Wilaiphorn Thinkhamrop Kinley Wangdi Matthew J.Kelly Apiporn T.Suwannatrai Darren J.Gray | 2019 | Infectious Diseases of Poverty2019，8，2： | 0 |
| 4 | Effects of albendazole,artesunate,praziquantel and miltefosine,on Opisthorchis viverrini cercariae and mature metacercariae显示文摘Objective:To explore larvicidal effects of anthelmintic drugs on Opisthorchis viverrini(O.viverrini) for alternative approach to interrupting its cycle for developing a field-based control program.Methods:The larvicidal activities of albendazole(A1),artesunate(Ar),praziquantel(Pzq) and miltefosine(Mf) on O.viverrini cercariae and mature metacercariae were investigated.Lethal concentrations(LC_(50) and LC_(95)) of these drugs were determined.Mature metacercariae previously exposed to various concentrations of the drugs were administered to hamsters.Worms were harvested 30 d post infection and worm recovery rates calculated.Al,Ar,Pzq and Mf produced morphological degeneration and induced shedding tails of cercariae after 24 h exposure.Results:The LC_(50) and LC_(95) of Al,Ar,Pzq and Mf on cercariae were 0.720 and 1.139,0.350 and 0.861,0.017 and 0.693,and 0.530 and 1.134 ppm,respectively.LC_(50) and LC_(95) of Ar on mature metacercariae were 303.643 and 446.237 ppm and of Mf were 289.711 and 631.781 ppm,respectively but no lethal effect in Pzq-and Al-treated groups(up to 1 ppt).No worms were found in hamsters administered Pzq-treated metacercariae.The adult worms from Al-treated metacercariae were significantly bigger in size compared to the control group(P<0.05).Fecundity and body width were greater in adults from Mf-treated metacercariae compared to the control group(P<0.05).Conclusions:The larvicidal effects of these drugs were high efficacy to O.viverrini cercariae but lesser efficacy to metacercariae.It should be further studied with the eventual aim of developing a field-based control program. | Phornphitcha Pechdee Monticha Chaiyasaeng Chanisala Sereewong Jukkrid Chaiyos Apiporn Suwannatrai Sutee Wongmaneeprateep Smarn Tesana | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，2： | 0 |
| 5 | Correction to:Repeated praziquantel treatment and Opisthorchis viverrini infection:a population-based crosssectional study in northeast Thailand显示文摘In the original publication of this article[1],there is an error in the section of‘Ethics approval and consent to participate’at the end of the article,the correct Ethics reference number should be HE551404 rather than HE591067. | Kavin Thinkhamrop Narong Khuntikeo Paiboon Sithithaworn Wilaiphorn Thinkhamrop Kinley Wangdi Matthew J.Kelly Apiporn T.Suwannatrai Darren J.Gray | 2019 | Infectious Diseases of Poverty2019，8，3： | 0 |
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