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| 1 | Large bowel injuries during gynecological laparoscopy显示文摘Laparoscopy is one of the most frequently preferred surgical options in gynecological surgery and has advantages over laparotomy, including smaller surgical scars, faster recovery, less pain and earlier return of bowel functions. Generally, it is also accepted as safe and effective and patients tolerate it well. However, it is still an intra-abdominal procedure and has the similar potential risks of laparotomy, including injury of a vital structure, bleeding and infection. Besides the wellknown risks of open surgery, laparoscopy also has its own unique risks related to abdominal access methods,pneumoperitoneum created to provide adequate operative space and the energy modalities used during the procedures. Bowel, bladder or major blood vessel injuries and passage of gas into the intravascular space may result from laparoscopic surgical technique. In addition, the risks of aspiration, respiratory dysfunction and cardiovascular dysfunction increase during laparoscopy. Large bowel injuries during laparoscopy are serious complications because 50% of bowel injuries and60% of visceral injuries are undiagnosed at the time of primary surgery. A missed or delayed diagnosis increases the risk of bowel perforation and consequently sepsis and even death. In this paper, we aim to focus on large bowel injuries that happen during gynecological laparoscopy and review their diagnostic and management options. | Kahraman ülker Turgut Anuk Murat Bozkurt Yetkin Karasu | 2014 | World Journal of Clinical Cases2014，2，12： | 9 |
| 2 | One fifth of hospitalizations for peptic ulcer-related bleeding are potentially preventable显示文摘AIM:To calculate the proportion of potentially preventable hospitalizations due to peptic ulcer disease(PUD),erosive gastritis(EG)or duodenitis(ED).METHODS:Retrospective cohort study using ICD-10codes to identify all patients with upper gastrointestinal hemorrhage secondary to endoscopically proven PUD,EG or ED during the period from March 2007 to October 2010 in three major metropolitan hospitals in Melbourne,Australia.Patients were divided into'high risk'(those who would benefit from gastroprotection)and'not high risk'groups as defined by established guidelines.Mean Rockall score,transfusion requirement,length of stay,rebleeding rates,need for surgery and in-hospital mortality was compared between'high risk'and'not high risk'groups.Within the'high risk'group,those on gastroprotection and those with no gastroprotection were also compared.RESULTS:Five hundred and seven patients were included for analysis of which 174 were classified as high risk.Median values of complete Rockall Score(5vs 4,P=0.002)and length of stay(5 d vs 4 d,P=0.04)were higher in the high risk group but in-hospital mortality was lower(0.6%vs 3.9%,P=0.03).130out of the 174 patients in the high risk group were not taking recommended gastroprotective therapy prior to hospitalization.Past history of PUD(OR=3.7,P=0.006)and clopidogrel use(OR=3.2,P=0.007)significantly predicted prescription of gastroprotective therapy.Using proton pump inhibitor protection rates of 50%-85%from published studies,an estimation of13%to 22%of the total number of the hospitalizations due to PUD or EG/ED related bleeding may have been preventable.CONCLUSION:Up to one fifth of all hospitalizations for bleeding secondary to PUD or EG/ED are potentially preventable. | Ray Boyapati Sim Ye Ong Bei Ye Anuk Kruavit Nora Lee Rhys Vaughan Sanjay Nurkar Peter Gibson Mayur Garg | 2014 | World Journal of Gastroenterology2014，20，30： | 8 |
| 3 | Prognostic implication of admission inflammatory profile in acute ischemic neurological events显示文摘 | Anuk T Assayag EB Rotstein R | 2002 | Acta Neurol Scand2002，106，4： | 1 |
| 4 | Genetic associations of inflammatory bowel disease in a South Asian population显示文摘AIM To estimate prevalence and phenotypic associations of selected inflammatory bowel disease(IBD)-associated genetic variants among Sri Lankan patients. METHODS A case study of histologically confirmed ulcerative colitis(UC) or Crohn's disease(CD) patients with ≥ 1 year disease duration, who were compared to unrelated, gender-matched, healthy individuals as controls, was conducted at four major centers in Sri Lanka. Phenotypic data of the cases were obtained and all participants were genotyped for 16 selected genetic variants: IL12 B :rs1045431, IL23 R :rs11805303, ARPC2 :rs12612347, IRGM :rs13361189, IL26/IL22 :rs1558744, CDH1 :rs1728785, IL10 :rs3024505, FCGR2 A :rs3737240, PTGER4 :rs4613763, IL17 REL/PIM3 :rs5771069, HNF4 a :rs6017342, STAT3 :rs744166, SMURF1 :rs7809799, LAMB1 :rs886774, HLA-DRB5, DQA1, DRB1, DRA :rs9268853, MST1, UBA7, and APEH :rs9822268. The genotypes of all variants were in Hardy-Weinberg Equilibrium(P > 10^(-3)). To account for multiple hypothesis testing, P-values < 0.003 were considered significant.RESULTS A total of 415 patients and 465 controls were recruited. Out of the single nucleotide polymorphisms(SNPs) tested, the majority were not associated with IBD in Sri Lankans. Significant positive associations were noted between rs886774(LAMB1-gene) and UC(odds ratio(OR) = 1.42, P = 0.001). UC patients with rs886774 had mild disease(OR = 1.66, P < 0.001) and remained in remission(OR = 1.48, P < 0.001). A positive association was noted between rs10045431(IL 12 B gene) and upper gastrointestinal involvement in CD(OR = 4.76, P = 0.002). CONCLUSION This confirms the heterogeneity of allelic mutations in South Asians compared to Caucasians. Most SNPs and disease associations reported here have not been described in South Asians. | Madunil Anuk Niriella Isurujith Kongala Liyanage Senerath Kuleesha Kodisinghe Arjuna Priyadarsin De Silva Nimna Rajapakshe Sunali D Nanayakkara Dunya Luke Thilakshi Silva Metthananda Nawarathne Ranjith K Peiris Udaya P Kalubovila Sujeewa R Kumarasena Vajira Harshadeva Weerabaddana Dissanayake Rohan W Jayasekara Hithanadura Janaka de Silva | 2018 | World Journal of Clinical Cases2018，6，15： | 1 |
| 5 | Prognostic implications of admission inflammatory profile in acute ischemic neurological events显示文摘 | Anuk T Assayag EB Rotstein R | 2002 | Acta Neurol Scand2002，106，1： | 1 |
| 6 | InflammationinAlzheimersdisease:Amyloid-βoligomerstriggerinnateimmunitydefenceviapatternrecognitionreceptors显示文摘 | ANTEROS JOHANNAO ANUK etal | 2009 | ProgNeurobiol2009，87，3： | 1 |
| 7 | Prognostic implications of admission inflammatory profile in acute ischemic neurological events 显示文摘 | Anuk T Assayag EB Rotstein R | 2002 | Acta Neurol Scand2002，106，4： | 1 |
| 8 | DOUBLE INVASIVE FUNGAL INFECTION AND TYPHLITIS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA显示文摘 | Zekai Avci Bulent Alioglu Deniz Anuk Ozlem Yilmaz Ozbek Ozlem Kurt Azap Namik Ozbek | 2008 | Pediatric Hematology-Oncology2008，，2： | 1 |
| 9 | Prognostic implications of admission inflammatory profile in acute ischemic neurological events显示文摘 | Anuk T Assayag EB Rotstein R | 2002 | Acta Neurol Scand2002，106，： | 1 |
| 10 | Immune responses to nmltiple antigen peptides containing T and B epitopes from Plasmodium falciparum circtnmsporozoite protein of Brazilian individuals naturally exposed to malaria显示文摘 | Avila SL Goldberg AC Anuk VG | 2001 | Parasite Immunol2001，23，2： | 1 |
| 11 | Evaluation of peripheral perfusion in term newborns before and after Yintang (EX-HN 3) massage显示文摘OBJECTIVE: To identify how acupressure on the acupoint Yintang(EX-HN 3) impacts oxygen saturation, pulse rate, and peripheral perfusion in term-born infants without underlying disease.METHODS: Infants born between weeks 37 and 42 of gestation were included in this study. The polyclinic's neonatology room was noise-controlled and made half-dark to prevent the perfusion index from being confounded. A pulse oximeter was linked to the baby's left lower extremity. Acupressure was applied on Yintang(EX-HN 3) for 30 s clockwise, held for 30 s, and then acupressure was applied for another 30 s counterclockwise. The baby's SaO_2, pulse rate, and perfusion index were recorded for each minute before and after acupressure.RESULTS: When pre- and post-acupressure pulse rate values were compared, a significant decrease in pulse rate values after acupressure application was observed. When pre- and post-acupressure oxygen saturation values were compared, a significant increase in post-acupressure oxygen saturation was observed. In addition, peripheral perfusion increased significantly after acupressure.CONCLUSION: Acupressure application has been used in traditional medicine for many years. However, it is not yet widely used in modern medicine.This study shows the impact of acupressure on neonatal skin perfusion, oxygen saturation, and pulse rate. | Ali Ulas Tugcu Tugrul Cabioglu Aslihan Abbasoglu Ayse Ecevit Deniz Anuk Ince Aylin Tarcan | 2015 | Journal of Traditional Chinese Medicine2015，35，6： | 1 |
| 12 | Acupuncture in Preterm Babies during Minor Painful Procedures显示文摘Objective: To evaluate analgesic effects of acupuncture in preterm neonates during minor painful procedures. Methods: Ten preterm neonates requiring heel prick for blood gas analysis were enrolled in the study, which had a crossover design. Oxygen saturation, systolic and diastolic blood pressure, respiratory rate, heart rate, and crying duration were recorded before and after heel prick. Babies were given expressed breast milk before each procedure. Patients were randomly assigned to receive acupuncture or not, and the groups were crossed over on the following day, so that patients who had received acupuncture received only breast milk, and the previous breast milk only group received both acupuncture and breast milk. The neonatal infant pain scale (NIPS) was used for pain evaluation. Results: Crying duration and NIPS pain scores during heel prick were lower in the neonates who had received acupuncture. Conclusion: Acupuncture is an effective method for the treatment of pain in neonates. | Ayse Ecevit Deniz Anuk Ince Aylin Tarcan Mehmet Tugrul Cabioglu Abdullah Kurt | 2011 | Journal of Traditional Chinese Medicine2011，31，4： | 0 |
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