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| 1 | Clinical importance of aspirin and clopidogrel resistance显示文摘Aspirin and clopidogrel are important components of medical therapy for patients with acute coronary syndromes, for those who received coronary artery stents and in the secondary prevention of ischaemic stroke. Despite their use, a significant number of patients experience recurrent adverse ischaemic events. Interindividual variability of platelet aggregation in response to these antiplatelet agents may be an explanation for some of these recurrent events, and small trials have linked 'aspirin and/or clopidogrel resistance', as measured by platelet function tests, to adverse events. We systematically reviewed all available evidence on the prevalence of aspirin/clopidogrel resistance, their possible risk factors and their association with clinical outcomes. We also identified articles showing possible treatments. After analyzing the data on different laboratory methods, we found that aspirin/clopidogrel resistance seems to be associated with poor clinical outcomes and there is currently no standardized or widely accepted definition of clopidogrel resistance. Therefore, we conclude that specific treatment recommendations are not established for patients who exhibit high platelet reactivity during aspirin/clopidogrel therapy or who have poor platelet inhibition by clopidogrel. | Gergely Feher Andrea Feher Gabriella Pusch Katalin Koltai Antal Tibold Beata Gasztonyi Elod Papp Laszlo Szapary Gabor Kesmarky Kalman Toth | 2010 | World Journal of Cardiology2010，2，7： | 36 |
| 2 | Budesonide induces complete remission in autoimmune hepatitis显示文摘瞄准:泼尼松和 azathioprine 为自体免疫的肝炎(AIH ) 代表标准疗法。然而,仅仅, 65% 病人进入完全的组织学的宽恕。最近, budesonide (芽) 被报导是一种有希望的选择。在这研究,我们在 AIH 估计了芽的功效和安全。方法:十八个病人(12 个女人, 6 个男人;吝啬的年龄 45.4+/-21 年) 与芽(Budenofalk ) 与 AIH 被对待在上面三次每日、跟随的 3 mg 为至少 24 wk.Seven,病人们也有主要胆汁性肝硬变(n=5 ) 或主要致硬化的胆管炎(n=2 ) 的特征。先进的肝纤维变性或肝硬化在 6 个病人是在场的。结果:十五(83%) 病人们有完全的临床、生物化学的宽恕。十个病人,与尖锐肝炎包括五,作为首要的治疗被给芽,哪个七进入宽恕。三个病人,二与肝肝硬化,没改善。有第二线的治疗的所有病人经历了长期的宽恕。组织学的宽恕也在三个病人被看见。临床上相关的导致芽的副作用与肝肝硬化(n=4 ) 仅仅在病人被记录。结论:芽在在我们有 AIH.Side 效果的病人的多数的宽恕正式就职是有效的,治疗失败主要与肝肝硬化在病人被观察。 | Antal Csepregi Christoph R(o|¨)cken Gerhard Treiber Peter Malfertheiner | 2006 | World Journal of Gastroenterology2006，12，9： | 14 |
| 3 | Gut barrier failure biomarkers are associated with poor disease outcome in patients with primary sclerosing cholangitis显示文摘AIM To assess the prevalence of a panel of serologic markers that reflect gut barrier dysfunction in a mixed cohort of pediatric and adult primary sclerosing cholangitis(PSC) patients.METHODS Sera of 67 PSC patients [median age(range): 32(5-79) years, concomitant IBD: 67% and cirrhosis: 20%] were assayed for the presence of antibodies against to F-actin(AAA Ig A/Ig G) and gliadin(AGA Ig A/Ig G)] and for serum level of intestinal fatty acid-binding protein(I-FABP) by ELISA. Markers of lipopolysaccharide(LPS) exposure [LPS binding protein(LBP)] and various antimicrobial antibodies [anti-OMP Plus Ig A and endotoxin core Ig A antibody(Endo CAb)] were also determined. Poor disease outcome was defined as orthotopic liver transplantation and/or liver-related death during the follow-up [median: 99(14-106) mo]. One hundred and fifty-three healthy subjects(HCONT) and 172 ulcerative colitis(UC) patients were the controls. RESULTS A total of 28.4%, 28.0%, 9% and 20.9% of PSC patients were positive for AAA Ig A, AAA Ig G, AGA Ig A and AGA Ig G, respectively. Frequencies of AAA Ig A and AAA Ig G(P < 0.001, for both) and AGA Ig G(P = 0.01, for both) but not AGA Ig A were significantly higher compared to both of the HCONT and the UC groups. In survival analysis, AAA Ig A-positivity was revealed as an independent predictor of poor disease outcome after adjusting either for the presence of cirrhosis [HR = 5.15(1.27-20.86), P = 0.022 or for the Mayo risk score(HR = 4.24(0.99-18.21), P = 0.052]. AAA Ig A-positivity was significantly associated with higher frequency of antimicrobial antibodies(P < 0.001 for Endo Cab Ig A and P = 0.012 for anti-OMP Plus Ig A) and higher level of the enterocyte damage marker(median I-FABP_(AAA Ig A pos vs neg): 365 vs 166 pg/m L, P = 0.011), but not with serum LBP level. CONCLUSION Presence of Ig A type AAA identified PSC patients with progressive disease. Moreover, it is associated with enhanced mucosal immune response to various microbial antigens and enterocyte damage further highlighting the importance of the gut-liver interaction in PSC. | Tamas Tornai Eszter Palyu Zsuzsanna Vitalis Istvan Tornai David Tornai Peter Antal-Szalmas Gary L Norman Zakera Shums Gabor Veres Antal Dezsofi Gabriella Par Alajos Par Peter Orosz Ferenc Szalay Peter Laszlo Lakatos Maria Papp | 2017 | World Journal of Gastroenterology2017，23，29： | 5 |
| 4 | Reversibility of visual field defects through induction of brain plasticity: vision restoration, recovery and rehabilitation using alternating current stimulation显示文摘For decades visual field defects were considered irreversible because it was thought that in the visual system the regeneration potential of the neuronal tissues is low.Nevertheless,there is always some potential for partial recovery of the visual field defect that can be achieved through induction of neuroplasticity.Neuroplasticity refers to the ability of the brain to change its own functional architecture by modulating synaptic efficacy.It is maintained throughout life and just as neurological rehabilitation can improve motor coordination,visual field defects in glaucoma,diabetic retinopathy or optic neuropathy can be improved by inducing neuroplasticity.In ophthalmology many new treatment paradigms have been tested that can induce neuroplastic changes,including non-invasive alternating current stimulation.Treatment with alternating current stimulation(e.g.,30 minutes,daily for 10 days using transorbital electrodes and^10 Hz)activates the entire retina and parts of the brain.Electroencephalography and functional magnetic resonance imaging studies revealed local activation of the visual cortex,global reorganization of functional brain networks,and enhanced blood flow,which together activate neurons and their networks.The future of low vision is optimistic because vision loss is indeed,partially reversible. | Bernhard A.Sabel Ying Gao Andrea Antal | 2020 | Neural Regeneration Research2020，15，10： | 5 |
| 5 | Black locust(Robinia pseudoacacia L.)as a multi-purpose tree species in Hungary and Romania:a review显示文摘Black locust(Robinia pseudoacacia L.) was the first North-American tree species imported to Europe at the beginning of the seventeenth century. It is commonly planted worldwide because of its adaptability to environmental stresses, its valuable wood, easy propagation, frequent and abundant seed production, excellent coppicing,high seedling survival, and relatively high wood yield. In Europe, Romania and Hungary have the most highly-developed black locust growing techniques and experiences.As a result of increasing interest in black locust in many countries, this review aims to provide a comprehensive overview of state-of-the-art site requirements, propagation, improvement and management(including growth and yield as well as use in energy plantations). | Valeriu-Norocel Nicolescu Cornelia Hernea Beatrix Bakti Zsolt Keseru Borbála Antal Károly Rédei | 2018 | Journal of Forestry Research2018，29，6： | 2 |
| 6 | A comparison of liquid hot water and steam pretreatments of sugar cane bagasse for bioconversion to ethanol显示文摘 | Mark Laser Deborah Schulman Stephen G Allen Joseph Lichwa Michael J Antal Lee R Lynd | 2001 | Bioresource Technology2001，，1： | 2 |
| 7 | 显示文摘 | Péter Antal Torok Gabriella Tóth Géza | 1998 | Journal of Chromatography A1998，797，： | 2 |
| 8 | Acute exacerbation of autoimmune hepatitis induced by Twinrix显示文摘We report on a 26-year-old man who presented with severe jaundice and elevated serum liver enzyme activities after having received a dose of Twinrix(○R). In his past medical history, jaundice or abnormal liver function tests were never recorded. Following admission, an elevated immunoglobulin G level and antinuclear antibodies at a titer of 320 with a homogenous pattern were found. Histology of a liver biopsy showed marked bridging liver fibrosis and a chronic inflammation, compatible with autoimmune hepatitis. Treatment was started with budesonide and ursodeoxycholic acid,and led to complete normalization of the pathological liver function tests. We believe that Twinrix(○R) led to an acute exacerbation of an unrecognized autoimmune hepatitis in our patient. The pathogenesis remains to be clarified. It is tempting to speculate that inactivated hepatitis A virus and/or recombinant surface antigen of the hepatitis B virus -as seen in patients with chronic hepatitis C and unrecognized autoimmune hepatitis who were treated with interferon alpha-might have been responsible for disease exacerbation. | Antal Csepregi Gerhard Treiber Christoph R(o|¨)cken Peter Malfertheiner | 2005 | World Journal of Gastroenterology2005，11，26： | 2 |
| 9 | Ionic Elastomers for Electric Actuators and Sensors显示文摘In the past decades,ion conductive polymers and elastomers have drawn worldwide attention for their advanced functions in batteries,electroactive soft robotics,and sensors.Stretchable ionic elastomers with dispersed soft ionic moieties such as ionic liquids have gained remarkable attention as soft sensors,in applications such as the wearable devices that are often called electric skins.A considerable amount of research has been done on ionic-elastomer-based strain,pressure,and shear sensors;however,to the best of our knowledge,this research has not yet been reviewed.In this review,we summarize the materials and performance properties of engineered ionic elastomer actuators and sensors.First,we review three classes of ionic elastomer actuators—namely,ionic polymer metal composites,ionic conducting polymers,and ionic polymer/carbon nanocomposites—and provide perspectives for future actuators,such as adaptive four-dimensional(4D)printed systems and ionic liquid crystal elastomers(iLCEs).Next,we review the state of the art of ionic elastomeric strain and pressure sensors.We also discuss future wearable strain sensors for biomechanical applications and sports performance tracking.Finally,we present the preliminary results of iLCE sensors based on flexoelectric signals and their amplification by integrating them with organic electrochemical transistors. | Chenrun Feng C.P.Hemantha Rajapaksha Antal Jákli | 2021 | Engineering2021，7，5： | 2 |
| 10 | 显示文摘 | Péter Antal Torok Gabriella Armstrong Daniel W | 2000 | Journal of Chromatography A2000，904，： | 2 |
| 11 | 应用“A”型外展支具治疗股骨头缺血性坏死疗效分析显示文摘股骨头缺血性坏死的最佳治疗方法一直存在争议。包容治疗和手术包容治疗各有利弊。近期多中心的研究结果显示对于中度的股骨头缺血性坏死病变采用股骨或骨盆截骨术其结果优于未手术的患者。但对于大龄和严重的股骨头坏死病例,其结果并不理想。 | 刘双 张立军 Sandor Kiss Tamas Terebessy Gyorgy Szoke Janos Kiss Imre Antal Miklos Szendroi | 2014 | 中国矫形外科杂志2014，22，7： | 2 |
| 12 | Cellulose pyrolysis kinetics:The current states of knowledge 显示文摘 | Antal M J | 1995 | Ind Eng Chem Res1995，34，3： | 1 |
| 13 | compairson of pharmacokinetics and pharmacodynamics of short-and long-term glyburide therapy in NIDDM显示文摘 | Jaber LA Antal EJ Slaughter RL | 1994 | Diabetes Care1994，17，： | 1 |
| 14 | Preparation of ativated carbons from macadamia nut shell and coconut shell by air activation 显示文摘 | Tam M S Antal M J | 1999 | Ind Eng Res1999，38，11： | 1 |
| 15 | Nutrition and Life Style in the Elderly-risk Factors and Recommendations显示文摘 | Antal M Regly-M6rei A | 2011 | Orv Hetil2011，152，5： | 1 |
| 16 | Sewage Sludge Carbonization for Terra Preta Applications显示文摘 | TAKUYA YOSHIDA MICHAEL JERRY ANTAL | 2009 | Energy Fuels2009，23，11： | 1 |
| 17 | Position-specificity of facial adaptation显示文摘 | Gyula Kovács Márta Zimmer Irén Harza Andrea Antal Zoltán Vidnyánszky | 2005 | NeuroReport2005，，17： | 1 |
| 18 | Formation of charcoal from biomass in a sealed reactor显示文摘 | Antal M J Jr Piroska S | 1992 | Ind Eng Chem Res1992，31，： | 1 |
| 19 | Cellulose pyrolysis kinetics: The current state of knowledge显示文摘 | VARHEGYI G | 1995 | Ind Eng Chem Res1995，34，3： | 1 |
| 20 | Hydrogen production by steam reforming glucose in supercritical water显示文摘 | Yu D Aihara M Antal Jr M J 1993 | 1993 | Energy Fuels1993，7，： | 1 |
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