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| 1 | OsSPL18 controls grain weight and grain number in rice显示文摘Grain weight and grain number are two important traits directly determining grain yield in rice. To date,a lot of genes related to grain weight and grain number have been identified; however, the regulatory mechanism underlying these genes remains largely unknown. In this study, we studied the biological function of OsSPL18 during grain and panicle development in rice. Knockout (KO) mutants of OsSPL18exhibited reduced grain width and thickness, panicle length and grain number, but increased tiller number. Cytological analysis showed that OsSPL18 regulates the development of spikelet hulls by affecting cell proliferation. qRT-PCR and GUS staining analyses showed that OsSPL18 was highly expressed in developing young panicles and young spikelet hulls, in agreement with its function in regulating grain and panicle development. Transcriptional activation experiments indicated that OsSPL18is a functional transcription factor with activation domains in both the N-terminus and C-terminus, and both activation domains are indispensable for its biological functions. Quantitative expression analysis showed that DEP1, a major grain number regulator, was significantly down-regulated in OsSPL18 KO lines.Both yeast one-hybrid and dual-luciferase (LUC) assays showed that OsSPL18 could bind to the DEP1promoter, suggesting that OsSPL18 regulates panicle development by positively regulating the expression of DEP1. Sequence analysis showed that OsSPL18 contains the OsmiR156k complementary sequence in the third exon; 5?RLM-RACE experiments indicated that OsSPL18 could be cleaved by OsmiR156k. Taken together, our results uncovered a new OsmiR156k-OsSPL18-DEP1 pathway regulating grain number in rice. | Hua Yuan Peng Qin Li Hu Shijie Zhan Shifu Wang Peng Gao Jing Li Mengya Jin Zhengyan Xu Qiang Gao Anping Du Bin Tu Weilan Chen Bingtian Ma Yuping Wang Shigui Li | 2019 | Journal of Genetics and Genomics2019，46，1： | 8 |
| 2 | Selective laser melting of dense and crack-free AlCoCrFeNi_(2.1) eutectic high entropy alloy: Synergizing strength and ductility显示文摘Additively manufactured high-entropy alloys generally suffer from low strength and/or poor ductility.In this work,by leveraging the good castability of eutectic high entropy alloys and high cooling rate of selective laser melting(SLM),we report a nearly fully dense and crack-free as-SLM AlCoCrFeNi_(2.1) eutectic high entropy alloy with an exceptional strength-ductility synergy,showing an ultrahigh yield strength of 982.1±35.2 MPa and an ultimate tensile strength of 1322.8±54.9 MPa together with an elongation to fracture of 12.3±0.5%.Such strength-ductility enhancement is owing to the heterogeneous eutectic microstructure consisting of the columnar,equiaxed,and“L-shape”cells with much refined sizes down to nanoscales.The morphology of cells in the transition zone is related to the misorientation between the growth direction of adjacent layers.This heterogeneous eutectic microstructure is the result of the graingrowth behavior dominated by the mechanisms of the epitaxial growth and growth of heterogeneous nuclei in SLM.Our current results provide a new methodology for the future design of ultrahigh-strength and ductile SLM-fabricated metallic materials including HEAs,and other printable alloys for various structural applications. | Lin He Shiwei Wu Anping Dong Haibin Tang Dafan Du Guoliang Zhu Baode Sun Wentao Yan | 2022 | Journal of Materials Science & Technology2022，，22： | 2 |
| 3 | Homing and differentiation of mesenchymal stem cells delivered intravenously to ischemic myocardium in vivo: a time-series study显示文摘 | Wenhui Jiang Aiqun Ma Tingzhong Wang Ke Han Yu Liu Yanmin Zhang Anping Dong Yuan Du Xin Huang Jun Wang Xinjun Lei Xiaopu Zheng | 2006 | Pflügers Archiv - European Journal of Physiology2006，，1： | 1 |
| 4 | Effects of V addition on the mechanical properties at elevated temperatures in a γ”-strengthened NiCoCr-based multi-component alloy显示文摘Ni Co Cr-based multi-component alloys have drawn much attention due to their exceptional ductility and strain hardening capacity.However,insufficient strength-ductility synergy of NiCoCr alloy has always been an issue that prevents it from extensive applications.According to our previous research,the precipitation ofγ”phase can significantly improve the strength-ductility synergy of this alloy system at room temperature.In this study,the effects of V addition onγ”phase stability and high-temperature mechanical properties have been explicitly investigated.The results indicate that V addition can stabilize the metastableγ”phase in this alloy system and prevent it from transforming into a stableδphase at grain boundaries upon 650℃aging,resulting in improved mechanical properties at elevated temperatures.The specific strength ofγ”-strengthened multi-component NiCoCr-based alloy can reach up to 86.2 MPa gcmat 650℃,which is higher than those of Ni-based superalloys,IN 939 and Waspaloy.This work provides theoretical guidance for the novel design of γ”-strengthened alloy for high-temperature applications. | Yunwei Pan Anping Dong Yang Zhou Dafan Du Donghong Wang Guoliang Zhu Baode Sun | 2022 | Journal of Materials Science & Technology2022，，12： | 0 |
| 5 | Characteristics ofβ-type Ti-41Nb alloy produced by laser powder bed fusion:Microstructure,mechanical properties and in vitro biocompatibility显示文摘Aβ-type Ti-41 Nb alloy with high relative density has been successfully fabricated by laser powder bed fusion(L-PBF)using pre-alloyed powders for potential implant application.The homogeneous microstructure can be achieved in L-PBF fabricated(L-PBFed)Ti-41 Nb alloy but slight composition segregation was detected along molten pool boundaries.The L-PBFed alloy was dominated by typical epitaxial columnar grains with strong(001)grain orientation along building direction(BD),and cellular structure was distinguished within the columnar grains.The main reasons for this microstructure can be attributed to effective thermal gradient and epitaxial growth.L-PBFed alloy exhibited higher mechanical strength compared with cold rolling plus annealing(CRA)alloy due to the finer grains,dislocations accumulation and different TRIP behaviors,accompanied by good ductility.It also exhibited much lower thermal conductivity and better hydrophilic feature than those of CP-Ti.Besides,the L-PBFed alloy exhibited slightly better cell spread and cell proliferation rates compared with CP-Ti.Moreover,L-PBFed alloy presented better alkaline phosphatase(ALP)activities and extracellular matrix(ECM)mineralization,which suggests that the L-PBFed alloy can stimulate the osteogenic differentiation of rat bone mesenchymal stem cells.The Ti-41 Nb alloy,fabricated by L-PBF,reveals a good combination of mechanical properties,physicochemical properties and biocompatibility,exhibiting the great potential as the dental implant. | Zhongjie Li Jiajun Qiu Hao Xu Anping Dong Lin He Guoliang Zhu Dafan Du Hui Xing Xuanyong Liu Baode Sun | 2022 | Journal of Materials Science & Technology2022，，29： | 0 |
| 6 | First Beam Commissioning of SSC-Linac as an Injector of SSC显示文摘The construction of the SSC-Linac has made significant progress in 2019.The first beam commissioning of SSC-Linac as an injector of the Separated Sector Cyclotron(SSC)was performed succssfully with ^(40)Ar^(7+) beam and the particle energy of 5.98 MeV/u was obtained at the exit of SSC on December 17,2019. | Du Heng Yin Xuejun Yang Weiqing Li Zhongshan Kong Qiyu Li Xiaoni Yang Shengli Qian Cheng WangHaoning Cong Yan Jin Peng Zhang Ruifeng Han Xiaodong Fu Xin Wang Kai Jing Long Zhang Yong Li Lili Xie Wenjun Xu Xiaowei Wang Shaoming Chen Wenjun Liu Xiaojun Yue Min An Jingrui Zhang Xiang Yan Huaihai Feng Anhui Zhang Shuai Zhang Yongbo Sun Peng Zhu Tieming Sha Xiaoping Xu Jianye Sun Xiaolong Su Xuemin Li Anping Yan Tailai Meng Jun Zhang Wei Wu Junxia Yao Qinggao Yang Yaqing Xu Zhe Sun Liangting Gao Daqing Yuan Youjin Yang Jiancheng Xia Jiawen | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
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