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| 1 | Inflammation and fibrosis in chronic liver diseases including nonalcoholic fatty liver disease and hepatitis C显示文摘At present chronic liver disease(CLD),the third commonest cause of premature death in the United Kingdom is detected late,when interventions are ineffective,resulting in considerable morbidity and mortality.Injury to the liver,the largest solid organ in the body,leads to a cascade of inflammatory events.Chronic inflammation leads to the activation of hepatic stellate cells that undergo transdifferentiation to become myofibroblasts,the main extra-cellular matrix producing cells in the liver;over time increased extra-cellular matrix production results in the formation of liver fibrosis.Although fibrogenesis may be viewed as having evolved as a“wound healing”process that preserves tissue integrity,sustained chronic fibrosis can become pathogenic culminating in CLD,cirrhosis and its associated complications.As the reference standard for detecting liver fibrosis,liver biopsy,is invasive and has an associated morbidity,the diagnostic assessment of CLD by non-invasive testing is attractive.Accordingly,in this review the mechanisms by which liver inflammation and fibrosis develop in chronic liver diseases are explored to identify appropriate and meaningful diagnostic targets for clinical practice.Due to differing disease prevalence and treatment efficacy,disease specific diagnostic targets are required to optimally manage individual CLDs such as non-alcoholic fatty liver disease and chronic hepatitis C infection.To facilitate this,a review of the pathogenesis of both conditions is also conducted.Finally,the evidence for hepatic fibrosis regression and the mechanisms by which this occurs are discussed,including the current use of antifibrotic therapy. | Sudeep Tanwar Freya Rhodes Ankur Srivastava Paul M Trembling William M Rosenberg | 2020 | World Journal of Gastroenterology2020，26，2： | 17 |
| 2 | Optimal energy aware clustering in sensor networks显示文摘 | Soheil Ghiasi Ankur Srivastava Yang Xiaojian | 2002 | Sensors2002，2，： | 1 |
| 3 | Adsorptive desulfurization by activated alumina显示文摘 | Ankur Srivastav Vimal Chandra Srivastava | 2009 | Journal of Hazardous Materials2009，，2： | 1 |
| 4 | Optimal Energy Aware Clustering in Sensor Networks显示文摘 | Soheil Ghiasi Ankur srivastava Xiaojian Yang and Majid Sarrafzadeh | 2002 | Sensors2002，2，： | 1 |
| 5 | Timing driven gate duplication显示文摘 | Srivastava Ankur Kastner Ryan and Chen Chun-hong | 2004 | IEEE Transactions on Very Large Scale Integration (VLS1) Systems2004，12，1： | 1 |
| 6 | Stromal Cell–Derived Factor-1α Is Cardioprotective After Myocardial Infarction显示文摘 | Ankur Saxena Jason E. Fish Michael D. White Sangho Yu James W.P. Smyth Robin M. Shaw J Michael DiMaio Deepak Srivastava | 2008 | Circulation2008，，17： | 1 |
| 7 | The impact of northern Indian Ocean rivers on the Bay of Bengal using NEMO global ocean model显示文摘The effect of river runoff over the northern Indian Ocean(NIO) especially over the Bay of Bengal(Bo B) has been studied using global Nucleus for European Modelling of the Ocean(NEMO). Two sensitivity experiments, with and without river runoff are conducted and the influence of river runoff on the Indian Ocean hydrography,stratification and circulation features are studied. It is found that due to river runoff surface salinity over the northern Bo B decreases by more than 5 and the East India Coastal Current strengthens by 2 cm/s during post monsoon season. The fresh river water reaches up to 15°N in the Bo B and is the main cause for low salinity there.Sea surface temperature in the northwestern Bo B increases by more than 0.2℃ due to the river runoff in summer monsoon while surface cooling upto 0.2℃ is seen in north-west part of Bo B in winter season. The seasonal mixed layer depth in the region is found to be dependent on river runoff. The effect of vertical shear and Brunt Vaisala frequency on stratification is also examined. The ocean water becomes highly stratified up to 3 035 m due to the river runoff. It is found that the energy required for mixing is high in the northern and coastal Bo B. | Atul Srivastava Anitha Gera Imran MMomin Ashis Kumar Mitra Ankur Gupta | 2020 | Acta Oceanologica Sinica2020，39，3： | 0 |
| 8 | Synthesis and enhanced photoluminescence properties of red emitting divalent ion(Ca^(2+))doped Eu:Y_(2)O_(3)nanophosphors for optoelectronic applications显示文摘This work presents the synthesis of Y_(2)O_(3):Eu^(3+),χCa^(2+)(χ=0 mol%,1 mol%,3 mol%,5 mol%,7 mol%,9 mol%,11 mol%)nanophosphors with enhanced photoluminescence properties through a facile solution combustion method for optoelectronic,display,and lighting applications.The X-ray diffraction(XRD)patterns of the proposed nanophosphor reveal its structural properties and crystalline nature.The transmission electron microscope(TEM)results confirm the change in the shape of the particle and aggregation of particles after co-doping with Ca^(2+).Fourier transform infrared spectroscopy(FTIR)and Raman vibrations also confirm the presence of Y-O vibration and subsequently explain the crystalline nature,structural properties,and purity of the samples.All the synthesized nanophosphors samples emit intense red emission at 613 nm(~5D_(0)→~7 F_(2))under excitation with 235,394 and 466 nm wavelengths of Eu^(3+)ions.The photoluminescence(PL)emission spectra excited with 235 nm illustrate the highest emission peak with two other emission peaks excited with 466 and 394 nm that is 1.4 times higher than 466 nm and 1.9 times enhanced by 394 nm wavelength,respectively.The emission intensity of Y_(2)O_(3):Eu^(3+),χCa^(2+)(5 mol%)is increased 8-fold as compared to Eu:Y_(2)O_(3).Doping with Ca^(2+)ions enhances the emission intensity of Eu:Y_(2)O_(3)nanopho sphors due to an increase in energy transfer in Ca^(2+)→Eu^(3+)through asymmetry in the crystal field and by introduction of radiative defect centers through oxygen vacancies in the yttria matrix.It is also observed that the optical band gap and the lifetime of the~5D_(0)level of Eu^(3+)ions in Y_(2)O_(3):Eu^(3+),xCa^(2+)nanophosphor sample gets changed with a doping conce ntration of Ca^(2+)ions.Nanophosphor also reveals high thermal stability and quantum yield as estimating activation energy of 0.25 eV and 81%,respectively.CIE,CCT,and color purity values(>98%)show an improved red-emitting nanophosphor in the warm region of light,which makes this mate rial superior with a specific potential application for UV-based white LEDs with security ink,display devices,and various other optoelectronics devices. | Arpita Dwivedi Monika Srivastava Ankur Dwivedi Amit Srivastava Anurag Mishra S.K.Srivastava | 2022 | Journal of Rare Earths2022，40，8： | 0 |
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