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		题名	作者	年代	出处	被引量
	1	Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: A randomized, double-blind study in urban Asia显示文摘AIM:Gastro-esophageal reflux disease (GERD) is becoming increasingly common in Asia. Data on the efficacy of proton pump inhibitors in patients with non-erosive GERD (NERD)in Asia is lacking. This double-blind study compared the efficacy and safety of rabeprazole with esomeprazole in relief of symptoms in patients with NERD.METHODS: One hundred and thirty-four patients with reflux symptoms of NERD and normal endoscopy were randomized to receive rabeprazole 10 mg or esomeprazole 20 mg once daily for 4 wk. Symptoms were recorded in a diary and changes in severity of symptoms noted.RESULTS: At 4 wk of treatment, rabeprazole 10 mg and esomeprazole 20 mg were comparable with regards to the primary endpoint of time to achieve 24-h symptomfree interval for heartburn 8.5 d vs9 d and regurgitation 6 d vs 7.5 d. Rabeprazole and esomeprazole were also similarly efficacious in term of patient's global evaluation with 96% of patients on rabeprazole and 87.9% of patients on esomeprazole, reporting that symptoms improved(P=NS). Satisfactory relief of day- and night-time symptoms was achieved in 98% of patients receiving rabeprazole and 81.4% of patients receiving esomeprazole. Adverse events were comparable in both groups (P = NS).CONCLUSION: Rabeprazole 10 mg has a similar efficacy and safety profile in Asians with NERD as esomeprazole 20 mg. Further study is necessary to investigate whether the small differences between the two drugs seen in this study are related to the improved pharmacodynamicpro perties of rabeprazole. Both drugs were well tolerated.	KM Fock EK Teo TL Ang TS Chua TM Ng YL Tan	2005	World Journal of Gastroenterology2005，11，20：	8
	2	Adenovirus expressing IFN-k (Ad/hIFN-k) produced anti-tumor effects through inducing apop- tosis in human tongue squamous cell carcinoma cell显示文摘	Song B ang Wang YL	2015	Int J Clin Exp Med2015，8，12：	1
	3	Best practice in the treatment of advanced squamous cell lung cancer显示文摘	Ang YL Tan HL Soo RA	2015	Ther Adv RespirDis2015，9，5：	1
	4	iTRAQ quantitative clinical proteomics revealed role of Na*-K + -ATPase and its correlation with deamidation in vascular dementia 显示文摘	Adav SS Qian J Ang YL	2014	J Proteome Res2014，13，11：	1
	5	TE-AFLP:combining rapidity and robustness in DNA fingerprinting显示文摘	van der Wurff ANG Chan YL van Straaln N M	2000	Nucleic Acids Res2000，28，24：	1
	6	Cytokines and hert failure 显示文摘	Wang W ANG YL	2007	J Appl Clin Pe- diatr2007，22，：	1
	7	Al t e rna t e synthe s i s of apixaba n (BMS-562247), an inhibitor of blood coagulation factor Xa 显示文摘	J i ang JA J i YL	2013	Synth Commun2013，43，1：	1
	8	Noninva- sive and invasive ventilation in acute respira- tory failure associated with bronchiectasis 显示文摘	Phua J Ang YL See KC	2010	Intensive Care Med2010，36，4：	1

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