|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | ConservativeapproachinPeutz-JeghersSyndrome:Single-balloon enteroscopyandsmallbowelpolypectomy显示文摘AIM: To assess the usefulness of the balloon assisted enteroscopy in preventing surgical intervention in pa-tients with Peutz-Jeghers syndrome (PJS) having a small bowel large polyps. METHODS: Seven consecutive asymptomatic pts(age 15-38 years) with PJS have been collected; six under-went polypectomy using single balloon enteroscopy(Olympus SIF Q180) with antegrade approach using push and pull technique. SBE system consists of the SIF-Q180 enteroscope, an overtube balloon control unit(OBCU Olympus Balloon Control Unit) and a dispos-able silicone splinting tube with balloon(ST-SB1). All procedures were performed under general anesthesia. Previously all pts received wireless capsule endos-copy(WCE). Prophylactic polypectomy was reservedmainly in pts who had polyps > 15 mm in diameter. The balloon is inflated and deflated by a balloon control unit with a safety pressure setting range from-6.0 kPa to +5.4 kPa. Informed consent has been obtained from pts or parents for each procedure.RESULTS: Six pts underwent polypectomy of small bowel polyps; in 5 pts a large polyp > 15 mm(range 20-50 mm in diameter) was resected; in 1 patient with WCE negative, SBE was performed for previous surgi-cal resection of gastrointestinal stromal tumors. In 2 pts endoscopic clips were placed due to a polypectomy. No surgical complication have been reported. SBE with resection of small bowel large polyps in PJS pts was useful to avoid gastrointestinal bleeding and emergency laparotomy due to intestinal intussuscep-tions. No gastrointestinal tumors were found in sub-sequent enteroscopic surveillance in all seven pts. In order surveillance, all pts received WCE, upper en-doscopy, ileocolonoscopy every 2 years. No pts had extraintestinal malignant lesions. SBE was performed when WCE was positive for significant polyps(> 15 mm).CONCLUSION: The effective of prophylactic polyp-ectomy of small bowel large polyps(> 15 mm) could be the first line treatment for conservative approach in management of PJS patients. | Torroni F Romeo E Rea F De Angelis P Foschia F Faraci S Federici di Abriola G Contini AC Caldaro T Dall’Oglio L | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 7 |
| 2 | Navigated liver surgery:State of the art and future perspectives显示文摘Background:In recent years,the development of digital imaging technology has had a significant influence in liver surgery.The ability to obtain a 3-dimensional(3D)visualization of the liver anatomy has provided surgery with virtual reality of simulation 3D computer models,3D printing models and more recently holograms and augmented reality(when virtual reality knowledge is superimposed onto reality).In addition,the utilization of real-time fluorescent imaging techniques based on indocyanine green(ICG)uptake allows clinicians to precisely delineate the liver anatomy and/or tumors within the parenchyma,applying the knowledge obtained preoperatively through digital imaging.The combination of both has transformed the abstract thinking until now based on 2D imaging into a 3D preoperative conception(virtual reality),enhanced with real-time visualization of the fluorescent liver structures,effectively facilitating intraoperative navigated liver surgery(augmented reality).Data sources:A literature search was performed from inception until January 2021 in MEDLINE(Pub Med),Embase,Cochrane library and database for systematic reviews(CDSR),Google Scholar,and National Institute for Health and Clinical Excellence(NICE)databases.Results:Fifty-one pertinent articles were retrieved and included.The different types of digital imaging technologies and the real-time navigated liver surgery were estimated and compared.Conclusions:ICG fluorescent imaging techniques can contribute essentially to the real-time definition of liver segments;as a result,precise hepatic resection can be guided by the presence of fluorescence.Furthermore,3D models can help essentially to further advancing of precision in hepatic surgery by permitting estimation of liver volume and functional liver remnant,delineation of resection lines along the liver segments and evaluation of tumor margins.In liver transplantation and especially in living donor liver transplantation(LDLT),3D printed models of the donor’s liver and models of the recipient’s hilar anatomy can contribute further to improving the results.In particular,pediatric LDLT abdominal cavity models can help to manage the largest challenge of this procedure,namely large-for-size syndrome. | Paschalis Gavriilidis Bjørn Edwin Egidijus Pelanis Ernest Hidalgo Nicola de’Angelis Riccardo Memeo Luca Aldrighetti Robert P Sutcliffe | 2022 | Hepatobiliary & Pancreatic Diseases International2022，21，3： | 6 |
| 3 | Recurrence and survival following microwave, radiofrequency ablation, and hepatic resection of colorectal liver metastases: A systematic review and network meta-analysis显示文摘Background: Gold standard for colorectal liver metastases(CRLM) remains hepatic resection(HR). However, patients with severe comorbidities, unresectable or deep-situated resectable CRLM are candidates for ablation. The aim of the study was to compare recurrence rate and survival benefit of the microwave ablation(MWA), radiofrequency ablation(RFA) and HR by conducting the first network meta-analysis. Data sources: Systematic search of the literature was conducted in the electronic databases. Both updated traditional and network meta-analyses were conducted and the results were compared between them. Results: HR cohort demonstrated significantly less local recurrence rate and better 3-and 5-year diseasefree(DFS) and overall survival(OS) compared to MWA and RFA cohorts. HR cohort included significantly younger patients and with significantly lower preoperative carcinoembryonic antigen(CEA) by 10.28 ng/m L compared to RFA cohort. Subgroup analysis of local recurrence and OS of solitary and ≤3 cm CRLMs did not demonstrate any discrepancies when compared with the whole sample. Conclusions: For resectable CRLM the treatment of choice still remains HR. MWA and RFA can be used as a single or adjunct treatment in patients with unresectable CRLM and/or prohibitive comorbidities. | Paschalis Gavriilidis Keith J Roberts Nicola de’Angelis Luca Aldrighetti Robert P Sutcliffe | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，4： | 4 |
| 4 | EASL clinical practice guidelines on the management of ascites,spontaneous bacterial peritonitis,and hepatorenal syndrome in cirrhosis显示文摘 | European Association for the Study of the Liver Gines P Angeli P | | Journal of Hepatology0，，： | 2 |
| 5 | The detrimental effects of lipopolysaccharideinduced neuroinflammation on adult hippocampal neurogenesis depend on the duration of the pro-inflammatory response显示文摘Adult hippocampal neurogenesis is a finely tuned process regulated by extrinsic factors. Neuroinflammation is a hallmark of several pathological conditions underlying dysregulation of neurogenesis. In animal models, lipopolysaccharide(LPS)-induced neuroinflammation leads to a neurogenic decrease mainly associated to the early inflammatory response. However, it is not well understood how the neuroinflammatory response progresses over time and if neurogenesis continues to be diminished during the late neuroinflammatory response. Moreover, it is unknown if repeated intermittent administration of LPS along time induces a greater reduction in neurogenesis. We administered one single intraperitoneal injection of LPS or saline or four repeated injections(one per week) of LPS or saline to young-adult mice. A cohort of new cells was labeled with three 5-bromo-2-deoxyuridine injections(one per day) 4 days after the last LPS injection. We evaluated systemic and neuroinflammation-associated parameters and compared the effects of the late neuroinflammatory response on neurogenesis induced by each protocol. Our results show that 1) a single LPS injection leads to a late pro-inflammatory response characterized by microglial activation, moderate astrocytic reaction and increased interleukin-6 levels. This response correlates in time with decreased neurogenesis and 2) a repeated intermittent injection of LPS does not elicit a late pro-inflammatory response although activated microglia persists. The latter profile is not accompanied by a continued longterm hippocampal neurogenic decrease. Hereby, we provide evidence that the neuroinflammatory response is a dynamic process that progresses in a milieu-dependent manner and does not necessarily lead to a neurogenic decrease, highlighting the complex interaction between the immune system and neurogenesis. | Martha Pérez-Domínguez Evangelina ávila-Mu?oz Eduardo Domínguez-Rivas Angélica Zepeda | 2019 | Neural Regeneration Research2019，14，5： | 2 |
| 6 | The prognostic value of spontaneous apoptosis, Bax, Bcl-2, and p53 in oral squamous cell carcinoma of the tongue 显示文摘 | XIE X CLAUSEN O P DE ANGELIS P | 1999 | Cancer1999，86，6： | 1 |
| 7 | Phosphorus removal from a real anaerobic supernatant by struvite crystallization 显示文摘 | Battistoni P de Angelis A Pavan P | 2001 | Water Researeh2001，35，9： | 1 |
| 8 | Comparison between two high-dose methylprednisolone schedules in the treatment of acute hepatic cellular rejection in liver transplant recipients:a controlled clinical trial显示文摘 | VOLPIN R ANGELI P GALIOTO A | 2002 | Liver Transplantation2002，8，6： | 1 |
| 9 | Angiotensin converting enzyme inhibitors and calcium channel blockers for coronary heart disease and stroke prevention 显示文摘 | Verdecchia P Reboldi G Angeli F | 2005 | Hypertension2005，46，2： | 1 |
| 10 | A placebo-controlled clini- cal trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis显示文摘 | MERKEL C MARIN R ANGELI P | 2004 | Gastroenterology2004，127，： | 1 |
| 11 | Total factor carbon e-mission performance; a malmquist index analysis显示文摘 | ZHOU P ANG B W HAN J Y | 2010 | En-ergy Economics2010，32，1： | 1 |
| 12 | Total factor carbon emission performance: a malmquist index analysis显示文摘 | Zhou P Ang B W Han J Y | 2010 | Energy Economics2010，32，1： | 1 |
| 13 | Gundersen flaps inthe management of ocular surface disease in an Asian pop- ulation 显示文摘 | LIM L S HOW A C ANG L P | 2009 | Conea2009，28，7： | 1 |
| 14 | Total Factor Carbon Emission Performance: A Malmquist Index Analysis 显示文摘 | Zhou P Ang ]3 W Han J Y | 2010 | Energy Economics2010，32，1： | 1 |
| 15 | Optimaldesign of PID process controllers based on genetic algorithm s显示文摘 | W ANG P KW OK D P | | 0，，4： | 1 |
| 16 | Direct Evidence on the Marginal Rate of Taxation on Dividend Income显示文摘 | Peterson P Ang J S | 1997 | Journal of Financial Economics1997，14，2： | 1 |
| 17 | Elevated plasma fibrinogen and diabetes mellitus are associated with lower inhibition of platelet reactivity with clopidogrel显示文摘 | Ang L Palakodeti V Khalid A Tsimikas S Idrees Z Tran P | 2008 | J Am Coll Cardiol2008，52，： | 1 |
| 18 | Measuring environmental per- formance under different environmental DEA technologies 显示文摘 | ZHOU P ANG B W POH K L | 2008 | En- ergy Economics2008，30，1： | 1 |
| 19 | Flow Structure in Horizontal Oil- Water Flow 显示文摘 | Angeli P Hewitt G | 2000 | International Journal of Multiphase Flow2000，26，7： | 1 |
| 20 | Solution-gated epitaxial grap- hene as pH sensor显示文摘 | ANG P K CHEN W WEE A T S et ai | 2008 | Joumal of the Am- eriean Chemical Society2008，130，14： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员