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| 1 | Defective T wave combined with incomplete right bundle branch block: a new electrocardiographic index for diagnosing atrial septal defect显示文摘 | WANG Mu-xuan WU Gui-fu GU Jing-li LI Li LU Kun YANG Da CHEN Long ZHANG Xi LUO Fu-tian Andrew D. Michaels MA Hong | 2012 | Chinese Medical Journal2012,,6: | 4 |
| 2 | Jurassic Black Shales Facies from Qiangtang Basin (Northern Tibet): Rare Earth and Trace Elements for Paleoceanographic Implications显示文摘The Biluo Co and Amdo 114 station, northern Tibet, cropping out the Early Toarcian and Middle-Late Tithonian (Jurassic) organic-rich black shales, have been a focus to petroleum geologists in discussing their oil-producing potential. This paper first reports the trace elements and rare earth elements to discuss the paleoenvironments, redox conditions and sedimentary mechanisms of those black shales. Both sections exhibit variation in trace element abundances with concentrations <0.1 ppm to 760 ppm, mostly enriched in V, Cr, Ni, Cu, Zn, Mo, Ba and U. Element ratios of Ni/Co, V/Cr, U/Th and V/(V+Ni) plus U were used to identify redox conditions. The shale-normalized rare earth element (REE) patterns are characterized by the flat-shale type with instable Ce anomalies and very weekly positive Eu anomalies. Positive Ceanom values are significant with values varying between - 0.064 and 0.029 in Biluo Co, which may be interpreted as release of REE and input of riverine terrestrial matter with rich Ce (resulting in pH change) during the anoxic conditions. In the middle parts of Amdo 114 station, distinct negative Ceanom values are observed (-0.238 to -0.111) and associated surface water warming were interpreted as being related to a major sea level rise. In contrast, the formation of the black shales in the lower and upper part of the studied succession took place during a cooler (Ceanom values >-0.10), lower surface water productivity, and lower sea-level stage. Thus, we emphasize the role of different factors that control the formation of local and regional black shales. The most important factors are sea-level fluctuations and increasing productivity. | CHEN Lan YI Haisheng TSAI Louis Loung-Yie XU Guiwen DA Xuejuan LIN Andrew Tien-Shun | 2013 | Acta Geologica Sinica(English Edition)2013,87,2: | 4 |
| 3 | Ly49 receptors activate angiogenic mouse DBA+ uterine natural killer cells显示文摘 | Patricia DA Lima Megan M Tu Mir Munir A Rahim Annie R Peng B Anne Croy Andrew P Makrigiannis | 2014 | Cellular & Molecular Immunology2014,11,5: | 3 |
| 4 | Role of eIF4E on epithelial-mesenchymal transition,invasion,and chemoresistance of prostate cancer cells显示文摘Dear Editor,Prostate cancer(PCa)is the most common cancer and second leading cause of cancer death for men in the United States[1].PCa with similar Gleason score has been reported to show substantial interpatient heterogeneity and differential prostate cancer-specific mortality rate[2].Such heterogeneity in PCa often results in different therapeutic responses among patients,including therapy resistance,therapeutic failure,relapse,and metastasis[3].Numerous oncogenes,such as eukaryotic translation initiation factor 4E(eIF4E),have been reported to be involved in epithelial-mesenchymal transition(EMT)and/or drug resistance in PCa[4].We previously demonstrated that eIF4E overexpression was involved in chemoresistance of triple-negative breast cancer and silencing eIF4E significantly inhibited cancer cell proliferation and sensitized cancer cells to chemotherapy in a patient-derived xenograft mouse model[5].In addition,eIF4E phosphorylation is known to stimulate the translation of matrix metalloproteinase 3(MMP3)and Snail mRNAs to promote EMT in PCa[6].Furthermore,the complexity and dynamic nature of EMT contributes to the heterogeneity of aggressive cancer cells[7].The precise role of eIF4E in EMT,invasion,and chemoresistance in PCa is still to be established with consideration of different subpopulations in order to develop precision medicine for PCa.In this work,we aimed to explore the role of eIF4E in EMT,invasion,and chemoresistance in PCa for establishing a promising new therapeutic strategy by regulating eIF4E expression using(1-aminoethyl)iminobis[Noleicylcysteinyl-1-aminoethyl)propionamide](ECO)/small interfering RNA(siRNA)nanoparticles previously developed in our lab[8-10]for PCa therapy in the context of tumor heterogeneity. | Xujie Liu Amita M Vaidya Da Sun Yan Zhang Nadia Ayat Andrew Schilb Zheng-Rong Lu | 2020 | Cancer Communications2020,40,2: | 2 |
| 5 | Regional and whole-body markers of nitric oxide production following hyperemic stimuli显示文摘 | Jason DA Frederick RC Andrew JG | 2005 | Free Radical Biology & Medicine2005,38,9: | 1 |
| 6 | Antioxidant enzyme and compound responses to chilling stress and their combining abilities in differentially sensitive maize hybrids 显示文摘 | HODGES DM ANDREWS CJ JOHNSON DA | 1997 | Crop Science1997,37,: | 1 |
| 7 | Classification for effective reha-bilitation:rediscovering psychology显示文摘 | Andrews DA Bonta J Hoge RD | 1990 | Crim Justice Behav1990,17,1: | 1 |
| 8 | Perceptions of nursing: Confirmation, change and the student experience 显示文摘 | Brodie DA Andrews GJ Andrews JP | 2004 | Int J Nurs Stud2004,41,7: | 1 |
| 9 | Lysophosphatidic acid opens a Ca^++ channel in human erythroeytes显示文摘 | Yang L Andrews DA Low PS | 2000 | Blood2000,95,7: | 1 |
| 10 | Lysophosphatidic acid opens a Ca2+ channel in human erythrocytes显示文摘 | Yang L Andrews DA Low PS | 2000 | Blood2000,95,7: | 1 |
| 11 | The molecular biology of the anemia of chronic disease: a hypothesis显示文摘 | Roy CN Weinstein DA Andrews NC | 2003 | Pediatr Res2003,53,3: | 1 |
| 12 | A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25 显示文摘 | Hysi PG Young TL Mackey DA Andrew T Ferndndez-Medarde A | 2010 | Nat Genet2010,42,10: | 1 |
| 13 | Sensitivity ofmaize hybrids to chilling and their combining abilities attwo developmental stages 显示文摘 | Hodges DM Andrews CJ Johnson DA | 1997 | Crop Science1997,37,: | 1 |
| 14 | Extracorpore- al membrane oxygenation-hemostatic complications显示文摘 | Murphy DA Hoekings LE Andrews RK | 2014 | Trans- fus Med Rev2014,18,: | 1 |
| 15 | Pcreeptions of nursing:confirmation, change and the student experience 显示文摘 | Brodie DA Andrews GJ Andrewsj P | 2004 | hat J N urs Stud2004,41,7: | 1 |
| 16 | The metabolism and immunology of bone显示文摘 | Watrous DA Andrews BS | 1989 | Semin Arthritis Rhem1989,19,: | 1 |
| 17 | Perceptions of Nursing: Confirmation,Change and the student experience显示文摘 | Brodie DA Andrews GJ Andrews JP | 2004 | Int J Nurs Stud2004,41,7: | 1 |
| 18 | Endoscopic ultrasound does not accurately stage early adenocarcinoma or high-grade dysplasia of the esophagus显示文摘 | Patrick EY Andrew BG Ruben DA | | 0,,08: | 1 |
| 19 | The molecular biology of the anemia of chronic disease: a hypothesis显示文摘 | Roy CN Weinstein DA Andrews NC | 2003 | Pediatr Res2003,53,: | 1 |
| 20 | Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea显示文摘 | Amselem J Cuomo C A van Kan J A Viaud M Benito E P Couloux A Coutinho P M de Vries R P Dyer PS Fillinger S Fournier E Gout L Hahn M Kohn L Lapalu N Plummer K M Pradier J M Quévillon E Sharon A Simon A ten Have A Tudzynski B Tudzynski P Wincker P Andrew M Anthouard V Beever R E Beffa R Benoit I Bouzid O Brault B Chen Z Choquer M Collémare J Cotton P Danchin E G Da Silva C Gautier A Giraud C Giraud T Gonzalez C Grossetete S Güldener U Henrissat B Howlett B J Kodira C Kretschmer M Lappartient A Leroch M Levis C Mauceli E Neuvéglise C Oeser B Pearson M Poulain J Poussereau N Quesneville H Rascle C Schumacher J Ségurens B Sexton A Silva E Sirven C Soanes D M Talbot N J Templeton M Yandava C Yarden O Zeng Q Rollins J A Lebrun M H Dickman M | 2011 | PLoS Genetics2011,7,10: | 1 |