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| 1 | 导致成人与儿童患者30天脑室腹腔分流失败的原因分析(英文)显示文摘OBJECTIVE The aim of this study was to provide a comprehensive benchmark of 30-day ventriculoperitoneal(VP)shunt failure rates for a single institution over a 5-year study period for both adult and pediatric patients,to compare this with the results in previously published literature,and to establish factors associated with shunt failure.METHODS A retrospective database search was undertaken to identify all VP shunt operations performed in a single,regional neurosurgical unit during a 5-year period.Data were collected regarding patient age,sex,origin of hydrocephalus,and whether the shunt was a primary or secondary shunt.Operative notes were used to ascertain the type of valve inserted,which components of the shunt were adjusted/replaced(in revision cases),level of seniority of the most senior surgeon who participated in the operation,and number of surgeons involved in the operation.Where appropriate and where available,postoperative imaging was assessed for grade of shunt placement,using a recognized grading system.Univariate and multivariate models were used to establish factors associated with early(30-day)shunt failure.RESULTS Six hundred eighty-three VP shunt operations were performed,of which 321 were pediatric and 362 were adult.The median duration of postoperative follow-up for nonfailed shunts(excluding deaths)was 1263 days(range 525-2226 days).The pediatric 30-day shunt failure rates in the authors'institution were 8.8%for primary shunts and 23.4%for revisions.In adults,the 30-day shunt failure rates are 17.7%for primary shunts and 25.6%for revisions.In pediatric procedures,the number of surgeons involved in the operating theater was significantly associated with shunt failure rate.In adults,the origin of hydrocephalus was a statistically significant variable.Primary shunts lasted longer than revision shunts,irrespective of patient age.CONCLUSIONS A benchmark of 30-day failures is presented and is consistent with current national databases and previously published data by other groups.The number of surgeons involved in shunt operations and the origin of the patient's hydrocephalus should be described in future studies and should be controlled for in any prospective work.The choice of shunt valve was not a significant predictor of shunt failure.Most previous studies on shunts have concentrated on primary shunts,but the high rate of early shunt failure in revision cases(in both adults and children)is perhaps where future research efforts should be concentrated. | Anderson IA Saukila LF Robins JMW Akhunbay-Fudge CY Goodden JR Tyagi AK Phillips N Chumas PD | 2018 | 中华神经外科疾病研究杂志2018，17，3： | 3 |
| 2 | Lauch of the bone and joint decade 2000 -2010显示文摘 | Delmas PD Anderson M | 2000 | Osteo Int2000，11，： | 2 |
| 3 | Ciliary neurotrophic factor activates leptin - like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin - resistant obesity 显示文摘 | Lambert PD Anderson KD Sleeman MW | 2001 | Proc Natl Acad Sci USA2001，98，8： | 1 |
| 4 | Trans-pyeloureteric anastomosis in the management of pelviureteric junction obstruction 显示文摘 | Anderson PD Anticich N Driver CP | 2001 | Aust NZJ Surg2001，71，： | 1 |
| 5 | Ureterocystoplasty: the latest developments显示文摘 | Dewan PA Anderson PD | 2001 | BJU Int2001，88，： | 1 |
| 6 | Breast engorgement:patterns and selected outcomes显示文摘 | Humenick SS Hill PD Anderson MA | 1994 | J Hum Lact1994，10，2： | 1 |
| 7 | Modulation of beta-laetam resistance in Staphylococcus aureus by catechins and gallates显示文摘 | STAPLETON PD SHAH S ANDERSON JC | 2004 | lnt J Antimicrob Agents2004，23，5： | 1 |
| 8 | Innate immunity modulates adipokines in humans显示文摘 | Anderson PD Mehta NN Wolfe ML | 2007 | J Clin Endocrinol Metab2007，92，6： | 1 |
| 9 | Nurses'knowledge and attitudes regarding pain assessment and intervention显示文摘 | Al-Shaer D Hill PD Anderson MA | 2011 | Medsurg Nurs2011，20，1： | 1 |
| 10 | Launch of the bone and joint decade 2000-2010显示文摘 | Delmas PD Anderson M | 2000 | Osteo Int2000，11，2： | 1 |
| 11 | Detection of hemizygosity in Hermansky Pudlak syndrome by quantitative real-time PCR显示文摘 | Griffin AE Cobb BR Anderson PD | 2005 | Clin Genet2005，68，1： | 1 |
| 12 | Bioterrorism:pathogens as wea- pons显示文摘 | Anderson PD Bokor G | 2012 | J Pharm Pract2012，25，5： | 1 |
| 13 | Impact of left ventricular function in relation to procedural outcomes following percutaneous coronary intervention: Insights from the British Cardi- ovascular Intervention Society显示文摘 | Mamas MA Anderson SG O'Kane PD | 2014 | Eur Heart J2014，35，43： | 1 |
| 14 | Nurses'knowledge and attitudes regarding pain assessment and intervention显示文摘 | Al-Shaer D Hill PD Anderson MA | 2011 | Medsurg Nurs2011，20，1： | 1 |
| 15 | Modulation of β-lactam resistance in Staphylococcus aureus by catechins and gallates显示文摘 | STAPLETON PD SHAH S ANDERSON JC | 2004 | Int J Antimicrob Agents2004，23，5： | 1 |
| 16 | Hermansky - Pudlak syndrome type 4 (HPS- 4): clinical and molecular characteristics显示文摘 | Anderson PD Huizing M Claassen DA | 2003 | Hum Genet2003，113，： | 1 |
| 17 | ^64Cu-TETA-octreoti- de as a PET imaging agent for patients with neuroendocrine tumors 显示文摘 | Anderson C J Dehdashti F Cutler PD | 2001 | J Nucl Med2001，42，2： | 1 |
| 18 | Emergency management of chemical weapons inju-ries显示文摘 | Anderson PD | | 0，，01： | 1 |
| 19 | The cilliary neurotrophic factor and its receptor, CNTFR alpha 显示文摘 | Anderson KD Lembert PD | 2000 | Pharm Acta Hdv2000，74，23： | 1 |
| 20 | Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates 显示文摘 | Stapleton PD Shah S Anderson JC | 2004 | Int J Antimicrob Agents2004，23，5： | 1 |
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