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| 1 | Ehealth:Low FODMAP diet vs Lactobacillus rhamnosus GG in irritable bowel syndrome显示文摘AIM:To investigate the effects of a low fermentable,oligosaccharides,disaccharides,monosaccharides and polyols diet(LFD)and the probiotic Lactobacillus rhamnosus GG(LGG)in irritable bowel syndrome(IBS).METHODS:Randomised,unblinded controlled trial on the effect of 6-wk treatment with LFD,LGG or a normal Danish/Western diet(ND)in patients with IBS fulfilling Rome III diagnostic criteria,recruited betweenNovember 2009 and April 2013.Patients were required to complete on a weekly basis the IBS severity score system(IBS-SSS)and IBS quality of life(IBS-QOL)questionnaires in a specially developed IBS web selfmonitoring application.We investigated whether LFD or LGG could reduce IBS-SSS and improve QOL in IBS patients.RESULTS:One hundred twenty-three(median age 37years,range:18-74 years),90(73%)females were randomised:42 to LFD,41 to LGG and 40 to ND.A significant reduction in mean±SD of IBS-SSS from baseline to week 6 between LFD vs LGG vs ND was revealed:133±122 vs 68±107,133±122 vs 34±95,P<0.01.Adjusted changes of IBS-SSS for baseline covariates showed statistically significant reduction of IBS-SSS in LFD group compared to ND(IBS-SSS score75;95%CI:24-126,P<0.01),but not in LGG compared to ND(IBS-SSS score 32;95%CI:18-80,P=0.20).IBS-QOL was not altered significantly in any of the three groups:mean±SD in LFD 8±18 vs LGG 7±17,LFD 8±18 vs ND 0.1±15,P=0.13.CONCLUSION:LFD is efficacious for patients with IBS. | Natalia Pedersen Nynne Nyboe Andersen Zsuzsanna Végh Lisbeth Jensen Dorit Vedel Ankersen Maria Felding Mette Hestetun Simonsen Johan Burisch Pia Munkholm | 2014 | World Journal of Gastroenterology2014，20，43： | 16 |
| 2 | Low-FODMAP diet reduces irritable bowel symptoms in patients with inflammatory bowel disease显示文摘AIM To investigate the effect of a low-FODMAP diet on irritable bowel syndrome(IBS)-like symptoms in patients with inflammatory bowel disease(IBD).METHODS This was a randomised controlled open-label trial of patients with IBD in remission or with mild-to-moderate disease and coexisting IBS-like symptoms(Rome III) randomly assigned to a Low-FODMAP diet(LFD) or a normal diet(ND) for 6 wk between June 2012 andDecember 2013. Patients completed the IBS symptom severity system(IBS-SSS) and short IBD quality of life questionnaire(SIBDQ) at weeks 0 and 6. The primary end-point was response rates(at least 50-point reduction) in IBS-SSS at week 6 between groups; secondary end-point was the impact on quality of life. RESULTS Eighty-nine patients, 67(75%) women, median age 40, range 20-70 years were randomised: 44 to LFD group and 45 to ND, from which 78 patients completed the study period and were included in the final analysis(37 LFD and 41 ND). There was a significantly larger proportion of responders in the LFD group(n = 30, 81%) than in the ND group(n = 19, 46%);(OR = 5.30; 95%CI: 1.81-15.55, P < 0.01). At week 6, the LFD group showed a significantly lower median IBSSSS(median 115; inter-quartile range [IQR] 33-169) than ND group(median 170, IQR 91-288), P = 0.02. Furthermore, the LFD group had a significantly greater increase in SIBDQ(median 60, IQR 51-65) than the ND group(median 50, IQR 39-60), P < 0.01.CONCLUSION In a prospective study, a low-FODMAP diet reduced IBS-like symptoms and increased quality of life in patients with IBD in remission. | Natalia Pedersen Dorit Vedel Ankersen Maria Felding Henrik Wachmann Zsuzsanna Végh Line Molzen Johan Burisch Jens Rikardt Andersen Pia Munkholm | 2017 | World Journal of Gastroenterology2017，23，18： | 15 |
| 3 | 射血分数保留的心力衰竭患者动脉硬化与运动的相关性显示文摘人类衰老以主动脉僵硬度增加为特征,通过降低动脉顺应性和增强收缩期波反射造成收缩期高血压。老年、高血压和肥胖是射血分数保留的心力衰竭(heart failure with preserved ejection fraction, HFpEF)发生发展最大的影响因素. | Reddy YNV Andersen MJ Obokata M Koepp KE Kane GC Melenovsky V Olson TP Borlaug BA 练桂丽 叶鹏 | 2017 | 中华高血压杂志2017，25，10： | 10 |
| 4 | Femtosec- ond laser-assisted cataract surgery with integrated optical coher- ence tomography显示文摘 | Palanker D V Blumenkranz M S Andersen D | 2010 | Sci Transl Med2010，2，58： | 1 |
| 5 | Intrauterine and deep cervical insemination with frozen semen in sheep 显示文摘 | Andersen V K Aamdal J | 1973 | Zuehthygiene1973，8，： | 1 |
| 6 | Characterization of sediments from Copenhagen Harbour by use of biotests显示文摘 | Pedersen F Bernestad E Andersen H V | 1998 | Water Science and Technology1998，37，67： | 1 |
| 7 | The ability of Fos family members to produce phenotypic changes in epitheloid cells is not directly linked to their transactivation potentials显示文摘 | Andersen H Mahmood S Tkach V | | 0，，31： | 1 |
| 8 | Effects of paradoxical sleep deprivation on blood parameters associated with cardiovascular risk in aged rats 显示文摘 | Andersen M L Martins P G F D'Almeida V | 2004 | Exp Gerontol2004，39，6： | 1 |
| 9 | C-Labeling and preliminare evaluation of vortioxetine as a PET radioligand 显示文摘 | Andersen V L Hansen H D Herth M M | 2014 | Bioorg Med Chem Lett2014，24，1： | 1 |
| 10 | Interemispheric correlation of late Fleistocene glacial events显示文摘 | LOWELL T V HEUSSER C J ANDERSEN B G | 1995 | Science1995，269，： | 1 |
| 11 | Fea- sibility of CHP-plants with thermal stores in the German spot market 显示文摘 | STRECKIENE G MARTINAITIS V ANDERSEN A N | 2009 | Applied Energy2009，86，11： | 1 |
| 12 | Endocrinological and catecholaminergic alterations during sleep deprivation and recovery in male rats显示文摘 | Andersen M L Martins P J D 'Almeida V | 2005 | J Sleep Res2005，14，1： | 1 |
| 13 | Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem eells显示文摘 | Nayak T R Andersen H Makam V S | 2011 | ACS Nano2011，5，6： | 1 |
| 14 | ls complete heart blockafter surgical closure of ventricular septum defects still an is- sue? 显示文摘 | Andersen H O de Levai M R Tsang V T | 2006 | Ann ThoracSurg2006，82，3： | 1 |
| 15 | Effect of glass fiber sizing on the cure kinetics of vinyl-ester resins 显示文摘 | Palmese G R Andersen O A Karbhari V M | 1999 | Composites Part A : Applied Science and Manufacturing1999，30，1： | 1 |
| 16 | Interactive Interpretation Of 4D Prestack Inversion Data Using Rock Physics Templates, Dual Classifica- tion, and Real-Time Visualization显示文摘 | Andersen C F Grosfeld V Wijngaarden A V | 2009 | The Leading Edge2009，28，8： | 1 |
| 17 | Supercontinuum generation in a photonic crystal fiber with two zero dispersion wavelengths显示文摘 | Hilligse K M Andersen T V Paulsen H N | 2004 | Optics Express2004，12，6： | 1 |
| 18 | E government Maturity Models: Extension of the Layne and Lee Model显示文摘 | Andersen K V Henriksen H Z | 2006 | Government Information Quarterly2006，23，2： | 1 |
| 19 | Patients with high-bonemass phenotype owing to LRP5-T2531 mutation have low plasma levels of serotonin显示文摘 | Frost M Andersen TE Yadav V | 2010 | J Bone Miner Resm2010，25，3： | 1 |
| 20 | Molecular activities,biosynthesis and evolution of triterpenoidsaponins显示文摘 | Augustin J M Kuzina V Andersen S B | 2011 | Phytochemistry2011，72，6： | 1 |
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