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| 1 | Empirical estimates of regional carbon budgets imply reduced global soil heterotrophic respiration显示文摘Resolving regional carbon budgets is critical for informing land-based mitigation policy.For nine regions covering nearly the whole globe,we collected inventory estimates of carbon-stock changes complemented by satellite estimates of biomass changes where inventory data are missing.The net land–atmospheric carbon exchange(NEE)was calculated by taking the sum of the carbon-stock change and lateral carbon fluxes from crop and wood trade,and riverine-carbon export to the ocean.Summing up NEE from all regions,we obtained a global‘bottom-up'NEE for net land anthropogenic CO_(2)uptake of–2.2±0.6 Pg C yr^(-1)consistent with the independent top-down NEE from the global atmospheric carbon budget during 2000–2009.This estimate is so far the most comprehensive global bottom-up carbon budget accounting,which set up an important milestone for global carbon-cycle studies.By decomposing NEE into component fluxes,we found that global soil heterotrophic respiration amounts to a source of CO_(2)of 39 Pg C yr^(-1)with an interquartile of 33–46 Pg C yr^(-1)—a much smaller portion of net primary productivity than previously reported. | Philippe Ciais Yitong Yao Thomas Gasser Alessandro Baccini Yilong Wang Ronny Lauerwald Shushi Peng Ana Bastos Wei Li Peter A.Raymond Josep G.Canadell Glen P.Peters Rob J.Andres Jinfeng Chang Chao Yue A.Johannes Dolman Vanessa Haverd Jens Hartmann Goulven Laruelle Alexandra G.Konings Anthony W.King Yi Liu Sebastiaan Luyssaert Fabienne Maignan Prabir K.Patra Anna Peregon Pierre Regnier Julia Pongratz Benjamin Poulter Anatoly Shvidenko Riccardo Valentini Rong Wang Grégoire Broquet Yi Yin Jakob Zscheischler Bertrand Guenet Daniel SGoll Ashley-P.Ballantyne Hui Yang Chunjing Qiu Dan Zhu | 2021 | National Science Review2021,8,2: | 3 |
| 2 | Development of a lavage solution associated with minimal water and electrolyte absorption or secretion显示文摘 | Davis GR Santa Ana CA Morawski SG Fordtran JS | 1980 | Gastroenterology1980,78,51: | 1 |
| 3 | Develop-ment of a lavage solution associated with minimal water and electrolyte ab- sorption or secretion 显示文摘 | Divas GR santa Ana CA Marawski SG | 1980 | Gastroenter-ology1980,78,51: | 1 |
| 4 | Cardiovascular effects caused by increasing concentrations of diesel exhaust in middle-aged healthy GSTM 1 null human volunteers显示文摘 | Tong HY Ana GR Melissa C | 2014 | lnhal Toxicol2014,26,: | 1 |
| 5 | Development of a layage solution associated with minimal water and electrolyte absorption or secretion显示文摘 | Santa Ana CA Morawski SG | 1980 | Gastroenterology1980,78,51: | 1 |
| 6 | Development of a lavage solution associated with minimal water and electrolyte absorption or secretion 显示文摘 | Davis GR Santa Ana CA Morawski SG | 1980 | Gastroenterology1980,78,51: | 1 |
| 7 | Development of a lavage solution associated with minimal water and electrolyte absorption or secretion显示文摘 | Davis GR Santa Ana CA Morawski SG | 1980 | Gastroenterology1980,78,51: | 1 |
| 8 | Development of a lavage solution associated with minimal water and electrolyte absorption or secretion显示文摘 | Davis GR Santa Ana CA Morawski SG | 1980 | Gastroenterology1980,78,51: | 1 |
| 9 | Development of a lavage solution associated with minimal water and dectrolyte absorption or secretion显示文摘 | Davis GR Santa Ana CA Morawski SG | 1980 | Gastroenterology1980,78,5: | 1 |
| 10 | Environmental risk factors for acute respiratory infections in hospitalized children under 5years of age in Ibadan,Nigeria显示文摘 | Fakunle GA Ana GR Ayede AI | 2014 | Paediatrics and International Child Health2014,34,2: | 1 |
| 11 | Development of a lavage solution associated with minimal water and electrolyte absorption or secretion显示文摘 | Davis GR Santa Ana CA Morawski SG | 1980 | Gastroenterology1980,78,3: | 1 |
| 12 | Global warming scenarios for the Eastern Adriatic Sea indicate a higher risk of invasiveness of non-native marine organisms relative to current climate conditions显示文摘Globally,marine bioinvasions threaten marine ecosystem structure and function,with the Mediterranean Sea being one of the most affected regions.Such invasions are expected to increase due to climate change.We conducted a risk screening of marine organisms(37 fishes,38 invertebrates,and 9 plants),both extant and‘horizon’(i.e.,not present in the area but likely to enter it).Based on expert knowledge for the Eastern Adriatic Sea coasts of Slovenia,Croatia,and Montenegro,screenings were conducted under both current and predicted climate conditions indicating with an increase in sea surface temperature and salinity of the Adriatic Sea together with changes in precipitation regime.Our aims were to:(1)identify non-native extant and horizon marine species that may pose threats to native biodiversity and(2)evaluate the risk of invasiveness of the selected species under current and predicted climate conditions.Of the 84 species screened,there was an increase in those ranked as‘high risk’from 33(39.3%)under current climate conditions and to 47(56.0%)under global warming scenarios.For those ranked as‘very high’risk,the increase was from 6(7.1%)to 21(25.0%).Amongst the screened species,the already established high-risk species Pacific oyster Magallana gigas and Atlantic blue crab Callinectes sapidus represent a threat to ecosystem services.Given the under-representation of marine species in the current European Union List,the species we have ranked as high to very high risk should be included. | Branko Glamuzina Lorenzo Vilizzi Marina Piria Ante Zuljevic Ana Bratos Cetinic Ana Pesic Branko Dragicevic Lovrenc Lipej Marijana Pecarevic Vlasta Bartulovic Sanja Grđan Ivan Cvitkovic Tatjana Dobroslavic Ana Fortic Luka Glamuzina Borut Mavric Jovana Tomanic Marija Despalatovic Domen Trkov Marina Brailo Scepanovic Zoran Vidovic Predrag Simonovic Sanja Matic-Skoko Pero Tutman | 2024 | Marine Life Science & Technology2024,6,1: | 0 |
| 13 | Constructal design method dealing with stiffened plates and symmetry boundaries显示文摘A new computational procedure for modelling the structural behavior of stiffened plates with symmetry boundary conditions is here presented.It uses two-dimensional finite elements as a way to decrease computational time without losing precision thanks to a relatively small number of elements applied for analyzing out-of-plane displacements(deflections)and stresses.Adding,the constructal design method was included in the procedure,together with the exhaustive search technique,with the scope to optimize the stress/strain status of stiffened plates by design changes.For the purpose,a reference plate without stiffeners was initially design and used as starting point.Part of the volume was reshaped into stiffeners:thickness was reduced maintaining unchanged weight,length and width.The main goal was to minimize strains and stresses by geometric changes.Results demonstrated that,thanks to this design procedure,it is always possible to find an adequate geometry transformation from reference plate into stiffeners,allowing significant improvements in mechanical behavior. | Rodrigo R.Amaral Grégori S.Troina Cristiano Fragassa Ana Pavlovic Marcelo L.Cunha Luiz A.O.Rocha Elizaldo D.dos Santos Liércio A.Isoldi | 2020 | Theoretical & Applied Mechanics Letters2020,10,5: | 0 |
| 14 | CXCR5^(+)PD-1^(++)CD4^(+)T cells colonize infant intestines early in life and promote B cell maturation显示文摘Gastrointestinal infections are a major cause for serious clinical complications in infants.The induction of antibody responses by B cells is critical for protective immunity against infections and requires CXCR5+PD-1++CD4+T cells(TFH cells).We investigated the ontogeny of CXCR5+PD-1++CD4+T cells in human intestines.While CXCR5+PD-1++CD4+T cells were absent in fetal intestines,CXCR5+PD-1++CD4+T cells increased after birth and were abundant in infant intestines,resulting in significant higher numbers compared to adults.These findings were supported by scRNAseq analyses,showing increased frequencies of CD4+T cells with a TFH gene signature in infant intestines compared to blood.Co-cultures of autologous infant intestinal CXCR5+PD-1+/−CD4+T cells with B cells further demonstrated that infant intestinal TFH cells were able to effectively promote class switching and antibody production by B cells.Taken together,we demonstrate that functional TFH cells are numerous in infant intestines,making them a promising target for oral pediatric vaccine strategies. | Ana Jordan-Paiz Glòria Martrus Fenja L.Steinert Max Kaufmann Adrian F.Sagebiel Renée R.C.E.Schreurs Anne Rechtien Martin E.Baumdick Johannes M.Jung Kimberly J.Möller Lucy Wegner Cordula Grüttner Laura Richert Roland Thünauer Jennifer Schroeder-Schwarz Johannes Bvan Goudoever Teunis B.H.Geijtenbeek Marcus Altfeld Steven T.Pals Daniel Perez Paul L.Klarenbeek Christian Tomuschat Guido Sauter Ingo Königs Udo Schumacher Manuel A.Friese Nathaniel Melling Konrad Reinshagen Madeleine J.Bunders | 2023 | Cellular & Molecular Immunology2023,20,2: | 0 |