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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Racial and ethnic differences in drug treatment entry of injection drug users in Massachusetts显示文摘 | Lundgren LM Amodeo M Ferguson F | 2001 | J Subst Abuse Treat2001，21，3： | 1 |
| 3 | Evaluation of neutrophil CD64 expression and proealcitonin as useful markers in early diagnosis of sepsis显示文摘 | Cardelli P Ferraironi M Amodeo R Tabaeeo F De Blasi R A Nieoletti M | 2008 | Int J Immunopathol Phar- maeol2008，21，： | 1 |
| 4 | The beneficial vortex and best spatial arrangement in total extracardiac cavopulmonary connection显示文摘 | AMODEO A GRIGIONI M OPPIDO G | 2002 | J Thorac Cardiovasc Surg2002，124，3： | 1 |
| 5 | The beneficialvortex and best spatial arrangement in total extracardiaccavopulmonary connection显示文摘 | Amodeo A Grigioni M Oppido G | 2002 | J Thorac Cardiovasc Surg2002，124，3： | 1 |
| 6 | Pefineural dexmedetomidine provides an increased duration of analgesia to a thermal stimulus when compared with a systemic control in a rat sciatic nerve block显示文摘 | Brummett C M Amodeo F S Janda A M | 2010 | Reg Anesth Pain Med2010，35，5： | 1 |
| 7 | Perineural dexmedetomidine added to ropivacaine causes a dose-depend- ent increase in the duration of thermal antinociception in sciatic nerve block in rat显示文摘 | Brummett C M Padda A K Amodeo F S | 2009 | Anesthesiology2009，111，5： | 1 |
| 8 | Towards the optimal Fontan operation : a single-institution experience显示文摘 | DONATO R M D AMODEO A GR1GIONI M | 2009 | Paediatrics and Child Health2009，19，1： | 1 |
| 9 | Evaluation of nentrophil CD64 expression and procalcitonin as useful markers in early diagnosis of sepsis显示文摘 | Cardelli P Ferraironi M Amodeo R | 2008 | Int J Immunopathol Pharmacol2008，21，1： | 1 |
| 10 | Evaluation of neutrophil CD64 expression and procalcitonin as useful markers in early diagnosis of sepsis显示文摘 | Cardelli P Ferraironi M Amodeo R | 2008 | Int J Immunopathol Pharmacol2008，21，1： | 1 |
| 11 | Gypsum nucleation into sodi um chloride solutions 显示文摘 | Marina P Amodeo L Dino M | 2001 | American Institute of Chemical Journal2001，47，4： | 1 |
| 12 | The beneficial vortex and best spatial arrangement in total extracardiac cavopulmonary connection显示文摘 | Amodeo A Grigioni M Oppido G | 2002 | J Thorac Cardiovasc Surg2002，124，3： | 1 |
| 13 | Wheel Slip Control via Second-Order Sliding-Mode Generation 显示文摘 | Amodeo M Ferrara A Terzaghi R | 2010 | IEEE Transactions on Intelligent Transportation Systems2010，11，1： | 1 |
| 14 | Structural requirements for proinflammatory activity of porin P2 Loop 7 from Haemophilus influenzae显示文摘 | Galdiero S Vitiello M Amodeo P | | 0，，14： | 1 |
| 15 | Structural re- quirements for proinflammatory activity of porin P2 Loop 7 from Haemophilus influenzae显示文摘 | Galdiero S Vitiello M Amodeo P | 2006 | Biochemis- try2006，45，： | 1 |
| 16 | Structural features in EIAV NCp11: a lentivirus nucleocapsid protein with a short linker显示文摘 | Amodeo P Castiglione Morelli M A Ostuni A | 2006 | Biochemistry2006，45，17： | 1 |
| 17 | Evaluation of neutrophil CD64 expression and procalcitonin as useful markers in early diagnosis of sepsis 显示文摘 | Cardelli P Ferraironi M Amodeo R | 2008 | Int J Immunopathol Pharmacol2008，21，1： | 1 |
| 18 | Charged residues distribution modulates selectivity of the open state of human isoforms of the voltage dependent anion-selective channel显示文摘 | Amodeo G F Scorciapino M A Messina A | 2014 | PLoS One2014，9，10： | 1 |
| 19 | Perineuraldexmedetomidine provides an increased duration of analgesia to athermal stimulus when compared with a systemic control in a rat sciaticnerve block显示文摘 | Brummett C M Amodeo F S Janda A M | 2010 | Reg Anesth Pain Med2010，35，5： | 1 |
| 20 | Evaluation of neutrophil CD64 expression and procalcitonin as useful markers in early diagnosis of sepsis显示文摘 | Cardelli P Ferraironi M Amodeo R | | 0，，01： | 1 |
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