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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Bilateral breast cancer显示文摘 | Amodeo C Caglia P Gandolfo L | 2003 | Tumori2003，89，4： | 1 |
| 3 | Bilateral breast cancer显示文摘 | Amodeo C Caglia P Gandolfo L | 2003 | Tumori2003，89，4： | 1 |
| 4 | Extracardiac Fontan operation for complex cardiac anomalies: seven years' experience 显示文摘 | Amodeo A Galletti L Marianeschi S | 1997 | J Thorac C ardiovasc Surg1997，114，： | 1 |
| 5 | Noven conceptin Ca2+channelselectivity显示文摘 | Amodeo C Kobrin L Ventura H | 1986 | Circulation1986，73，1： | 1 |
| 6 | New multi-objective method to solve reentrant hybrid flow shop scheduling problem显示文摘 | DUGARDIN F YALAOUI F AMODEO L | 2010 | European Journal of Operational Research2010，203，： | 1 |
| 7 | Multi - start iterated local search for the periodic vehicle routing problem with time windows and time spread constraints on services显示文摘 | Michallet J Pfins C Amodeo L | 2014 | Computers & Operations Research2014，41，： | 1 |
| 8 | Multi-start iterated local search for the periodic vehicle routing problem with time windows and time spread constraints on services显示文摘 | Michallet J Prins C Amodeo L | 2014 | Computers & Operations Research2014，41，： | 1 |
| 9 | Multi -start iterated local search for the periodic vehicle routing problem with time windows and time spread constraints on services显示文摘 | Michallet J Prins C Amodeo L | 2014 | Computers & operations research2014，，41： | 1 |
| 10 | Modeling and performance evaluation of supply chains using batch deter- ministic and stochastic Petri nets显示文摘 | CHEN Haoxun AMODEO L CHU Feng | 2005 | IEEE Transactions on Automation and Engineering2005，2，2： | 1 |
| 11 | Undifferentiated carcinoma of the thyroid 显示文摘 | Amodeo C Caglia P Gandolfo L | 2003 | Tumori2003，89，4： | 1 |
| 12 | Multi-start iterated local search for the periodic vehicle routing problem with time win- dows and time spread constraints on services显示文摘 | Michallet J Prins C Amodeo L | 2014 | Computers Operations Research2014，41，1： | 1 |
| 13 | The severity of acute kidney injury predicts progression to chronic kidney disease显示文摘 | CHAWLA L S AMDUR R L AMODEO S | 2011 | Kidney Int2011，79，12： | 1 |
| 14 | Extracardiac Fontan operation for complex cardiac anomalies:seven years'experience显示文摘 | Amodeo A Galletti L Marianeschi S | 1997 | J Thorac Cardiovasc Surg1997，114，6： | 1 |
| 15 | Physical and water sorption properties of chemically modified pectin with an environmentally friendly process显示文摘 | Monfregola L Bugatti V Amodeo P | 2011 | Biomacromolecules2011，12，6： | 1 |
| 16 | Modeling and performance evaluation of supply chains using batch deterministic and stochastic Petri nets 显示文摘 | Chen H Amodeo L Chu F | 2005 | IEEE Transactions on Automation Science and Engineering2005，2，2： | 1 |
| 17 | Gypsum nucleation into sodi um chloride solutions 显示文摘 | Marina P Amodeo L Dino M | 2001 | American Institute of Chemical Journal2001，47，4： | 1 |
| 18 | Ant colony optimiza- tion for solving an industrial layout problem 显示文摘 | Hani Y Amodeo L Yalaoui F | 2007 | European Journal of Operational Research2007，183，2： | 1 |
| 19 | Bi-objective optimiza-tion algorithms for joint production and maintenance scheduling:application to the parallel machine problem 显示文摘 | Berrichi A Amodeo L Yalaoui F | 2009 | Journal of Intel-ligent Manufacturing2009，20，4： | 1 |
| 20 | Bi-Objective Ant Colony Optimization approach to optimize production and maintenance scheduling 显示文摘 | Berrichi A Yalaoui F Amodeo L | 2010 | Computers Operations Research2010，37，9： | 1 |
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